[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"skin-brightening\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:skin-brightening":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":5},"100585204","the-effect-of-cosmetic-products-on-skin-brightening-100585204",false,"NCT06899321","The Effect of Cosmetic Products on Skin Brightening","A Clinical Study to Evaluate Test Products for Skin Brightening Benefit Under Controlled UV Exposure, in a 6-week Study Design","Inclusion Criteria:\n\n* Healthy female adult participants in general good health as determined from a recent medical history.\n* Participants in the age group of 18-45 years as on the day of enrolment (both ages inclusive).\n* Participants having very little hair, no burns, no cut\u002Fabrasion; no moles\u002Ftattoo\u002Fbirth marks\u002Fburn marks on the test sites\u002Fareas as identified on screening.\n* Participants with long and broad forearms.\n* Participants having skin photo-type IV and V.\n* Participants with Spectrophotometer L\\* value- 45 to 55 (both values included) on the identified test sites on the volar forearm.\n* Participants having uniform skin color and no sunburn\u002F erythema on the test sites.\n* Participants who do not have very dry or scaly skin, uneven skin tone on their volar forearms or no other signs of significant local irritation or skin disease like psoriasis.\n* Participants who agree to refrain from using pumice stone, scrubber while bathing during the study.\n* Participants who are willing to avoid direct sun exposure to the test sites.\n* Participants who have not participated in any clinical product evaluation test within past 1 month.\n* Participants able to read and sign an appropriate informed consent form indicating her willingness to participate and agree to come for regular study visits.\n* Participants willing to abide by and comply with the study protocol.\n* Participants willing to use umbrella \\& wear full covered attire if she has to go in sun.\n* Participants who are willing not to participate in any other clinical study during participation in the current study.\n\nExclusion Criteria:\n\n* Participants with a known history or present condition of allergic response to any sunscreen products, cosmetic products, bathing soaps, detergent powder or medicine.\n* Participants who have outdoor job, extremely physical (manual) job which could cause excessive sun exposure or sweating\n* Participants who are smokers.\n* Menopausal women.\n* Participants having active skin diseases which will interfere with the test readings.\n* Participants on oral and topical medications (e.g Steroids, anti-oxidant, antibiotics) which will compromise the study.\n* Systemic treatment which may modify the cutaneous state on the day of inclusion or in the previous 30 days, including retinoid therapy.\n* Participants who are pregnant, lactating or nursing.\n* Intense sun exposure\u002F photo allergenicity\u002Ftoxicity.\n* Chronic illness which may influence the cutaneous state.\n* Participants participating in any other cosmetic or therapeutic trial.\n* Participants with any underlying uncontrolled medical illness including diabetes mellitus, hypertension, liver disease or history of alcoholism, HIV, hepatitis, or any other serious medical illness that will pose a health risk due to study participation as per investigator's discretion.\n* For female participants only: be pregnant, planning pregnancy or lactating\u002Fnursing. Urine pregnancy testing (UPT) will be performed at the time of screening.",true,"FEMALE","18 Years","45 Years",{"count":21,"type":22},34,"ESTIMATED","INTERVENTIONAL",[25],"NA","This is a single centre, single cell, blinded study designed to evaluate the effect of 5 cosmetic products on skin brightening, skin hydration and skin barrier function of the volar forearm after controlled UV exposure as compared to baseline and a no-treatment control.",[28],"Skin Brightening","NOT_YET_RECRUITING","2025-03-20",{"date":32,"type":33},"2025-03-27","ACTUAL",{"date":35,"type":22},"2025-03",{"date":37,"type":22},"2025-05",{"name":39,"class":40},"Unilever R&D","INDUSTRY"]