[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"skin-graft-wounds\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:skin-graft-wounds":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,40,68],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":4},"100612777","comparison-of-dressing-materials-of-donor-site-of-split-thickness-skin-graft-paraffin-mesh-gauze-vs-povidone-iodine-foam-at-smbb-institute-of-trauma-karachi-100612777",false,"NCT07257991","Comparison of Dressing Materials of Donor Site of Split-thickness Skin Graft; Paraffin Mesh Gauze vs Povidone-Iodine Foam at SMBB Institute of Trauma Karachi","Inclusion Criteria:\n\n* Undergoing skin graft with donor site size between 25 to 200 cm2\n\nExclusion Criteria:'\n\n* Patients wit history of disease impairing wound healing (Diabetes, Malignancy, Cancer, taking immunosuppressants)\n* Pregnant or lactating females",true,"ALL","18 Years","75 Years",{"count":20,"type":21},82,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to learn if povidone-iodine foam dressing is better in achieving complete reepithelialization of donor site wounds after harvest of split-thickness skin graft as paraffin mesh gauze.\n\nThe main questions it aims to answer are:\n\nDoes povidone-iodine foam dressing promotes complete reepithelialization earlier in comparison? Which type of dressing will require fewer replacements? Which type of dressing material is associated with less pain?\n\nNon-probability consecutive sampling method will be used and participants divided in two groups. Donor site wounds after split-thickness skin graft harvest will be dressed using two different dressing materials. Participants will be followed until complete epithelialization with change of dressing on follow-ups if required. Complete epithelialization is usually achieved within two weeks.",[27],"Skin Graft Wounds","NOT_YET_RECRUITING","2025-12-05",{"date":31,"type":32},"2025-12-15","ACTUAL",{"date":34,"type":21},"2026-01-01",{"date":36,"type":21},"2026-05-01",{"name":38,"class":39},"Shaheed Mohtarma Benazir Bhutto Institue of Trauma","OTHER",{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":48,"enrollmentInfo":49,"targetDuration":4,"studyType":22,"phases":51,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":67},"100597366","aloe-vera-vs-paraffin-tulle-dressings-for-pain-management-in-split-thickness-skin-graft-donor-sites-100597366","NCT07057557","Aloe Vera vs Paraffin Tulle Dressings for Pain Management in Split Thickness Skin Graft Donor Sites","Comparison of Postoperative Pain After Application of Aloe Vera Gel Dressings With Conventional Paraffin-Based Tulle Dressings at Split-Thickness Skin Graft Donor Site","AloePaTu","Inclusion Criteria:\n\n* • Patients aged 18-60 years of age of either gender needing Split thickness skin graft\n\nExclusion Criteria:\n\n* • Patients known to have exaggerated\u002Fdiminished pain response due to certain medical conditions (e.g. diabetes, neuropathy, chemotherapy, opioids etc.)\n\n  * Patients allergic to either dressings","60 Years",{"count":50,"type":21},72,[24],"The goal of this clinical trial is to learn if Aloe Vera gel dressing helps reduce pain better than traditional paraffin-based tulle dressing at the donor site of split-thickness skin grafts in adult patients aged 18 to 60. The main questions it aims to answer are:\n\nDoes Aloe Vera gel dressing reduce postoperative pain more effectively than paraffin-based tulle dressing on the 7th day after surgery?\n\nIs there a difference in the need for additional pain medication between the two groups?\n\nResearchers will compare Aloe Vera gel dressing to paraffin-based tulle dressing to see if Aloe Vera leads to better pain control.\n\nParticipants will:\n\nUndergo split-thickness skin graft surgery\n\nReceive either Aloe Vera gel dressing or paraffin-based tulle dressing at the donor site\n\nHave pain measured using a visual analogue scale (VAS) on the 7th day after surgery\n\nBe given pain medication if their pain score is 4 or higher, and the amount used will be recorded",[27,54,55,56],"Donor Site Complication","Pain, Postoperative","Skin Transplantation","RECRUITING","2025-09-21",{"date":60,"type":32},"2025-09-25",{"date":62,"type":32},"2025-08-05",{"date":64,"type":21},"2026-04-14",{"name":66,"class":39},"King Edward Medical University",1,{"id":69,"slug":70,"hasResults":11,"nctId":71,"briefTitle":72,"officialTitle":72,"acronym":4,"eligibilityCriteria":73,"healthyVolunteers":11,"sex":16,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":4,"studyType":22,"phases":78,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":4},"100529148","efficacy-of-a-transparent-silicone-membrane-with-physical-microstructure-for-second-degree-burn-wounds-and-skin-graft-wounds-100529148","NCT06170008","Efficacy of a Transparent Silicone Membrane With Physical Microstructure for Second-degree Burn Wounds and Skin Graft Wounds","Inclusion Criteria:\n\n* Age 12 to 70 years, regardless of gender;\n* Second-degree burns with an area greater than 1% TBSA and a single observable trauma area ≥ 10 cm × 10 cm(jointly determined by two burn specialists with the title of attending physician or above according to the four degrees and five points method);\n* Voluntary signed informed consent form\n\nExclusion Criteria:\n\n* Patients during pregnancy;\n* Significant cardiac, pulmonary and renal insufficiency;\n* Critically ill or with serious complications such as severe sepsis or MODS;\n* Positive for HBV, HCV, HIV or syphilis;\n* Traumatic surface infection;\n* Involving the face, hands, groin, joints, feet and other areas difficult to bandage and fix; previous burn trauma treatment; previous burns on the same site; electrical burns; patients with inhalation injuries.\n* Known sensitivity or allergy to one of the dressings or its components; diabetes mellitus; presence of immune system disorders or long-term hormone or immunotherapy\n* Others who, in the opinion of the investigator, are not suitable for enrollment.","12 Years","70 Years",{"count":77,"type":21},40,[24],"The goal of this clinical trial is to comparison of physical microstructure-modified transparent silicone films and current conventional trauma dressings for second-degree burn wounds and post-skin graft wounds.The main question it aims to answer is :\n\nThe development of a new type of wound dressing is urgently needed because existing wound dressings cannot be transparent, easy to change, easy to store and inexpensive at the same time.\n\nParticipants will receive routine wound treatment, after which they will be covered with a clear silicone membrane with physical microstructure modification.\n\nResearchers will compare vaseline gauze group and decellularised pigskin group o see if transparent silicone film with physical microstructure modifications promotes wound healing, reduces the number of dressing changes, reduces the damage to the wound and painful irritation to the patient during dressing changes, thus improving the quality of wound repair and saving medical costs.",[81,27],"Second-degree Burn Wounds",[83,84,85],"Second-degree burn wounds","skin graft wounds","Wound coverings","2023-12-05",{"date":88,"type":32},"2023-12-14",{"date":90,"type":21},"2023-12-30",{"date":92,"type":21},"2026-12-30",{"name":94,"class":39},"Changhai Hospital"]