[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"sleep-apnea-central\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:sleep-apnea-central":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,41],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":4},"100600278","assessing-the-performance-of-wesper-lab-for-obstructive-and-central-sleep-apnea-100600278",false,"NCT07095413","Assessing the Performance of Wesper Lab for Obstructive and Central Sleep Apnea","Assessing the Performance of Wesper Lab for Obstructive and Central Sleep Apnea Diagnosis in Adult Populations","Inclusion Criteria:\n\n* Be at least 21 years of age\n* Have a referral to the study site from a physician to complete an overnight polysomnogram test for sleep apnea detection or follow-up.\n* Be willing and able to wear two Wesper Lab patches and an FDA-cleared pulse oximeter in conjunction with a polysomnogram, for a single night.\n* Be able and voluntarily willing to sign a written informed consent form prior to the initiation of any study procedures. Adult patients unable to provide written informed consent on their own behalf will not be eligible for the study.\n\nExclusion Criteria:\n\n* Women who are pregnant, trying to get pregnant or who have a positive urine pregnancy test on the day of the study.\n* Women who are breast-feeding\n* History of severe insomnia\n* Any known health condition that, in the opinion of the Investigator, would exclude the patient from participating in the study.","ALL","21 Years",{"count":19,"type":20},100,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical trial is to evaluate the effectiveness of the Wesper Lab home sleep apnea test as a tool to aid in the diagnosis of sleep apnea in adult patients (age ≥21 years) who are recommended for an overnight polysomnography (PSG) evaluation. The main questions it aims to answer are:\n\n1. Is Wesper Lab home sleep apnea test as accurate as an in-laboratory sleep study (polysomnography) for the diagnosis of obstructive and central sleep apnea?\n2. Is Wesper Lab accurate in a wide range of body types and skin types?\n\nParticipants will:\n\n1. Provide informed consent and complete a brief medical history.\n2. Undergo an overnight polysomnography sleep study while wearing two Wesper Lab patches and a compatible pulse oximeter.\n3. Have a follow-up communication within 5 days post-study to assess any adverse events.",[26,27,28],"Sleep Apnea","Sleep Apnea, Obstructive","Sleep Apnea, Central","NOT_YET_RECRUITING","2025-07-23",{"date":32,"type":33},"2025-07-31","ACTUAL",{"date":35,"type":20},"2025-09-01",{"date":37,"type":20},"2026-02-01",{"name":39,"class":40},"Wesper Inc","INDUSTRY",{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":53,"phases":4,"briefSummary":54,"conditions":55,"keywords":60,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":74},"100393144","apnea-stroke-and-incident-cardiovascular-events-100393144","NCT04399200","Apnea, Stroke and Incident Cardiovascular Events","Sleep Apnea Syndrome and Incidence of Major Adverse Cardiac and Cerebrovascular Events (MACCEs) After a First Stroke","ASCENT","Inclusion Criteria:\n\n* Male or female, aged 18 to 85 years\n* Admitted in the stroke unit no later than 72h after the onset of stroke symptoms:\n\n  * First stroke confirmed by computed tomography scan or magnetic resonance imaging, whatever the localization\n  * Initial or recurrent TIA, as defined by a brief and sudden neurological dysfunction for which an ischemic cause is presumed, with symptoms lasting less than 24 hours, and\u002For with no visible lesion on neuroimaging evaluation.\n* Score on the Modified Ranking scale (mRS) ≤1 before stroke\n* Signed informed consent by patient or his\u002Fher relative if not able\n* Patient eligible to carotid endarterectomy (for ancillary study only)\n\nExclusion Criteria:\n\n* Pregnant or breastfeeding women\n* Past history of stroke\n* Inability to follow rehabilitation procedure\n* Patients with ongoing treatment for SDB\n* Exclusion period for another study\n* Patients not affiliated to a French social and health insurance system or equivalent\n* Prisoners or patients who require protection by the law","18 Years","85 Years",{"count":52,"type":20},1620,"OBSERVATIONAL","This prospective cohort study aims to compare the proportion of cardiac or cerebrovascular events after a first stroke, a first transient ischemic attack (TIA) or recurrent TIA, between sleep-disordered breathing (SDB) and non-SDB (control) patients, one year after SDB diagnosis, performed 3 months after stroke onset.\n\nThe primary outcome is a composite endpoint composed of cardiac or cerebrovascular events regrouping: death from any cardiac or cerebrovascular cause, non-fatal stroke, and non-fatal acute coronary disease.\n\n1620 patients, in the acute phase of a first stroke, TIA or recurrent TIA will be included in the cohort.\n\nClinical, neuroimaging, sensorimotor, cognitive and biological parameters will be collected at inclusion. Three months after stroke or TIA onset, polysomnography will be performed for SDB diagnosis. Patients will be considered as having SDB for an Apnea-Hypopnea Index (AHI) \\> 15 events\u002Fhour, or to the control group otherwise. The same clinical, imaging, cognitive and biological assessments than during the first visit will be performed; incident (new) cardiovascular events will be collected. Three months later, and at 1, 2, 3, 4 and 5 years after SDB diagnosis, the same clinical, cognitive, sensorimotor, and sleep-related evaluations will be performed. In addition to the aforementioned parameters, incident cardiovascular outcomes will be collected, at the same time points. The primary study outcome will be retrieved one year after stroke onset.",[56,57,58,27,28,59],"Stroke","Sleep-disordered Breathing","Sleep Apnea Syndromes","Fragmentation, Sleep",[56,57,61,62],"Cardio-Vascular Events","Atherosclerosis","RECRUITING","2025-02-07",{"date":66,"type":33},"2025-02-11",{"date":68,"type":33},"2020-07-13",{"date":70,"type":20},"2035-06-01",{"name":72,"class":73},"University Hospital, Grenoble","OTHER",1]