[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"sleep-architecture\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:sleep-architecture":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,51],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100622552","evaluation-of-cognitive-behavioral-therapy-for-insomnia-cbt-i-in-individuals-with-mild-traumatic-brain-injury-mtbi-100622552",false,"NCT07385105","Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI)","Exploring Cognitive Behavioral Therapy for Insomnia (CBT-I) in Mild Traumatic Brain Injury (mTBI)","Inclusion Criteria:\n\n* A history of mTBI documented by a physician and sleep problems for more than 4 weeks\n* A score ≥ 10 on the Insomnia Severity Index (ISI)\n* Speak, read, and write English\n\nExclusion Criteria:\n\n* History of other neurological or psychological conditions\n* Patient Health Questionnaire-9 (PHQ-9) score higher than 20 (severe depressive symptoms)\n* Generalized Anxiety Disorder-7 (GAD-7) score higher than 15 (severe anxiety symptoms)\n* Montreal Cognitive Assessment (MoCA) score less than 24","ALL","18 Years","60 Years",{"count":20,"type":21},15,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study will employ cognitive behavioral therapy for insomnia (CBT-I) among individuals with mild traumatic brain injury (mTBI) who experience sleep disturbances. The research aims to evaluate the effects of CBT-I on sleep, mTBI symptoms, and, in particular, the ability of individuals with mTBI to engage in their desired daily life activities. The main questions this study aims to answer are:\n\n1. Does CBT-I positively impact symptoms of mTBI?\n2. Does CBT-I improve functional performance in individuals with mTBI?",[27,28,29,30],"Sleep Architecture","Mild Traumatic Brain Injury","Sleep","Sleep and Circadian Problems",[32,33,34,35,36,37],"Sleep problems","Cognitive behavioral Therapy for insomnia","CBT-I","mild traumatic brain injury","mTBI","Functional performance","RECRUITING","2026-04-27",{"date":41,"type":42},"2026-05-01","ACTUAL",{"date":44,"type":42},"2026-03-01",{"date":46,"type":21},"2027-01-01",{"name":48,"class":49},"University of Missouri-Columbia","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":61,"briefSummary":62,"conditions":63,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":5},"100576153","combining-light-therapy-and-cpap-in-depression-100576153","NCT06781593","Combining Light Therapy and CPAP in Depression","Effects of Light Therapy on Compliance With Continuous Positive Airway Pressure in a Population of Depressed Patients Newly Fitted With Devices for Obstructive Sleep Apnea","LUCIOPRESS","Inclusion Criteria:\n\n* Adults consulting at the MICHEL JOUVET unit, CH Le Vinatier, Bron\n* Adults with a diagnosis of major depressive episode (DSM-V) and with a MADRS score ≥ 15\n* Adults with a diagnosis of OSAS on ventilatory polygraphy or polysomnography (AASM 2017 criteria) requiring CPAP.\n\nExclusion Criteria:\n\n* Refusal to participate.\n* Pregnant and breast-feeding women\n* Under guardianship or curatorship.\n* Unstable psychiatric or physical pathology (e.g., hypomania, high suicidal risk) considered incompatible with the study by the investigators.\n* Other psychiatric, neurologic or somatic conditions\n* Contraindication to light therapy: retinopathy, retinitis pigmentosa, diabetic retinopathy, macular degeneration, glaucoma, recent eye surgery (less than 3 months).\n\npatient wishing to choose a provider other than the protocol provider.\n\n* Patient wishing to choose a device other than SEFAM's S-BOX or a mask other than the nasal mask at the time of introduction.\n* Nasal obstruction.\n* Refusal to use actimetry, refusal to use light therapy, refusal to use CPAP.",{"count":60,"type":21},130,[24],"In a double-blind, parallel-group controlled trial, we aim to measure the effect of two weeks of light therapy combined with the CPAP on compliance CPAP in patients with major depressive disorder.",[64,27,65,66,67,68],"Major Depression","Obstructive Sleep Apnea","Compliance","Continuous Positive Airway Pressure (CPAP)","Light Therapy","2025-04-24",{"date":71,"type":42},"2025-04-29",{"date":73,"type":42},"2025-01-17",{"date":75,"type":21},"2027-10-30",{"name":77,"class":49},"Hôpital le Vinatier"]