[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"sleep-disorder-breathing-related\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:sleep-disorder-breathing-related":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100526576","the-effect-of-sarcopenic-obesity-on-sleep-in-individuals-with-obesity-hypoventilation-syndrome-100526576",false,"NCT06136533","The Effect of Sarcopenic Obesity on Sleep in Individuals With Obesity Hypoventilation Syndrome","Inclusion Criteria:\n\n* \\>50 years old\n* 30\\\u003C BMI\\\u003C 45 kg\u002Fm2\n* Patients who have undergone polysomnography evaluation within the last 6 months\n\nExclusion Criteria:\n\n* Patient who have immobilized for more than 15 days in the last 6 months\n* Patient who have used corticosteroids in the last 6 months\n* Patient who have been significant weight loss in the last 6 months\n* Patient who have been significant serious comorbidities (cognitive impairments, neuromuscular diseases, unstable heart problems, uncontrolled respiratory problems, unresolved thyroid problems, etc.) that may affect participation in the study","ALL","50 Years",{"count":18,"type":19},64,"ESTIMATED","OBSERVATIONAL","Obesity Hypoventilation Syndrome(OHS) is characterized by daytime hypercapnia and sleep-disordered breathing without other causes of hypoventilation in individuals with a body mass index above 30 kg\u002Fm2. It is stated that obesity is at the basis of the metabolic changes seen in individuals diagnosed with OHS. Also sedentary lifestyle habits, which are common in obese individuals, cause the risk of sarcopenia due to loss of muscle strength and mass, accumulation of adipose tissue in the body, and decreased exercise capacity. Reduced exercise capacity due to obesity has been shown in the literature to strongly interact with mortality risk. As a result of obesity and all this negative picture, impaired emotional state and decreased quality of life are observed in individuals. Simultaneously, sleep parameters are also negatively affected. In particular, increased adipose tissue leads to loss of muscle mass and strength, increased risk of sarcopenia and sleep-related problems. The association of obesity and sarcopenia is referred to as 'sarcopenic obesity'. Sarcopenic obesity is defined as the coexistence of sarcopenia and obesity. The concept of sarcopenic obesity has recently taken its place in the literature. In particular, there are very few studies on its relationship with sleep parameters. However, while obesity is the basis of OHS, there are no studies on the presence and effects of sarcopenic obesity in this patient group. Based on this point, we aim to investigate the effects of sarcopenic obesity on sleep parameters, exercise capacity and quality of life in individuals with OHS.",[23,24,25,26,27,28,29],"Obesity Hypoventilation Syndrome (OHS)","Obesity","Hypoventilation","Respiration Disorders","Sleep Disorder; Breathing-Related","Sarcopenia","Sarcopenic Obesity",[23,24,28,29,31,32,27,33],"Sleep","Quality of Sleep","Polysomnography","NOT_YET_RECRUITING","2024-08-11",{"date":37,"type":38},"2024-08-13","ACTUAL",{"date":40,"type":19},"2025-07-10",{"date":42,"type":19},"2025-10-01",{"name":44,"class":45},"Istanbul University","OTHER"]