[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"sleep-inadequate\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:sleep-inadequate":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100471583","impact-of-sleep-duration-on-immune-balance-in-urban-children-with-asthma-100471583",false,"NCT05420766","Impact of Sleep Duration on Immune Balance in Urban Children With Asthma","AIMS","Inclusion:\n\n* Children 7-11 years old\n* Has physician-diagnosed asthma, per parent and pediatrician report\n* Meets criteria for current persistent asthma with a current prescription for an asthma controller medicine\n* Obtains 9.0-11.0 h of sleep per 24 h day in the past month\n* Has a positive allergy skin test performed at the clinic visit\n* Resides and attend school in one of the targeted urban areas (Rhode Island: East Providence, North Providence, Providence, Warwick, Cranston, Woonsocket, Central Falls, Pawtucket, Lincoln, Johnston. Massachusetts: Attleboro, North Attleboro, Fall River.\n* Has a primary caregiver who speaks English\n\nExclusion:\n\n* No asthma diagnosis\n* No use of asthma controller medication\n* Severe persistent asthma that is poorly controlled\n* Diagnosis of additional pulmonary disease or medical condition or immune deficiency disorders\n* Use of systemic steroids \\\u003C30 days of screening\n* Asthma-related emergency department visit and\u002For asthma-related hospitalization in past 90 days\n* Marked developmental delay, psychiatric conditions, academic\u002Fbehavioral problems, learning disabilities\n* Tanner stage 3-5 of pubertal development\n* Diagnosed ADHD; Use of stimulants to treat ADHD\n* An Apnea-Hypoxia Index \\>5 (indicator of sleep disordered breathing)","ALL","7 Years","11 Years",{"count":20,"type":21},204,"ESTIMATED","INTERVENTIONAL",[24],"NA","Urban children with asthma are at high risk for short sleep, due to an environment that jeopardizes both sleep and asthma management. Further, urban children with asthma suffer from altered immune balance, a key biological process contributing to individual differences in asthma morbidity and sleep health. In the proposed research, the researchers will examine the effects of shortened and recovery sleep on immune balance and associated changes in lung function in urban children with allergic asthma through an experimental design.",[27,28,29],"Asthma in Children","Sleep Hygiene","Sleep, Inadequate",[28,31,32],"Children with asthma","Immune function in children","RECRUITING","2025-09-19",{"date":36,"type":37},"2025-09-22","ACTUAL",{"date":39,"type":37},"2022-05-15",{"date":41,"type":21},"2026-07-31",{"name":43,"class":44},"Rhode Island Hospital","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":16,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":45},"100576380","the-effects-of-repeated-operational-stress-and-limited-recovery-on-resilience-capacity-100576380","NCT06784544","The Effects of Repeated Operational Stress and Limited Recovery on Resilience Capacity","REP DEF","Inclusion Criteria:\n\n* Men and women aged 18 - 39 years (17 - 39 years if military personnel)\n* Weight stable in the past 2 months (± approximately 5 kg)\n* Healthy without evidence of chronic illness or musculoskeletal injury as determined by the USARIEM Office of Medical Support and Oversight (OMSO) or home duty station medical support (HMS)\n* Functional exercise (i.e., step ups, box jumps, body mass movements) and\u002For aerobic exercise trained defined by self-report as performing ≥ 2 sessions\u002Fwk for previous 6 months\n* Willing to refrain from alcohol, smoking any nicotine product (includes e-cigarettes); vaping, chewing tobacco, caffeine not provided in the study, and dietary supplement use throughout the dietary interventions\n* Biological females must be on sustained (i.e., approximately \\>3 months) oral\u002Fhormonal contraceptive use which acts to maintain continuous hormonal levels (i.e., contains low-dose estrogen\u002Fprogesterone with no oral placebos, hormonal IUD)\n* Supervisor approval for federal civilian employees and non-HRV active duty military personnel)\n\nExclusion Criteria:\n\n* Musculoskeletal injuries that compromise exercise capability as determined by OMSO or HMS\n* Metabolic or cardiovascular abnormalities, sleep disorders (i.e., sleep apnea) gastrointestinal disorders (e.g., kidney disease, diabetes, cardiovascular disease, etc.) as determined by OMSO or HMS\n* Abnormal or problems with blood clotting as determined by OMSO or HMS\n* History of complications with lidocaine or similar local anesthetic analogue\n* Present condition of alcoholism, anabolic steroids, or other substance abuse issues\n* Blood donation within 8-wk of beginning or completing study blood draws\n* Current diagnosis of Anemia (hemoglobin \\\u003C 13 g\u002FdL for males, hemoglobin \\\u003C 12 g\u002FdL for females) and Sickle Cell Anemia\u002FTrait as determined by OMSO or HMS\n* Pregnant, trying to become pregnant, and\u002For breastfeeding (results of urine pregnancy test or self-report for breastfeeding will be obtained before body composition testing)\n* Claustrophobia or discomfort related to having enclosed equipment around the head\n* Unwillingness or inability to consume study diets or foods provided due to personal preference or food allergies\u002Fsensitivities\n* Unwillingness or inability to adhere to study exercise restrictions and prescriptions",true,"17 Years","39 Years",{"count":57,"type":21},24,[24],"This longitudinal study will examine the effects of repeated bouts of operational stress and limited recovery on integrated MPS, whole-body protein balance, iron absorption, and aerobic performance. Following baseline characterization measures, active adults (n=24) representative of normal weight phenotype (NW; n=12) and overweight phenotype (OW; n=12) will complete a 48h balance phase preceding two rounds of repeated 72h energy deficit exposure each immediately followed by a 48h recovery phase. NW cutoff will be defined ≤ 22% body fat for males and ≤ 32% body fat for females. OW cutoff will be defined as \\>22% body fat for males and \\>32% body fat for females. These body composition cutoffs are informed by the maximum allowable percent body fat standards outlined in current Army Regulation 600-9. Additional details for determining % body fat are outlined in the experimental procedures section of the protocol.",[29,61,62,63],"Energy Deficit","Iron Absorption","High Physical Activity","NOT_YET_RECRUITING","2025-01-14",{"date":67,"type":37},"2025-01-20",{"date":69,"type":21},"2025-05",{"date":71,"type":21},"2025-11",{"name":73,"class":74},"United States Army Research Institute of Environmental Medicine","FED"]