[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"sleep-inertia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:sleep-inertia":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100624457","association-between-slow-wave-activity-and-sleep-inertia-100624457",false,"NCT07409883","Association Between Slow Wave Activity and Sleep Inertia","Association Between Slow Wave Activity and Sleep Inertia in Nighttime Simulated Naps: An Observational Study With Nap Intervention","Inclusion Criteria:\n\n1. Age between 18 and 60 years\n2. History of appropriate sleep duration at least 6 hours\u002Fnight for a minimum of 2 weeks assessed by sleep diary before the trial\n\nExclusion Criteria:\n\n1. STOP-BANG ≥3 or previous diagnosis of obstructive sleep apnea\n2. Presence of restless legs syndrome as assessed with IRLSSG criteria\n3. Presence of depression as assessed by HADS (Exclude participants with HADS-Depression sub-scale score ≥8 (possible depression)\n4. History of irregular work hours or shift work within 2 weeks\n5. Use of sedative\u002Fhypnotic medications on a regular-basis (3 days\u002Fweek or above)\n6. History of epilepsy and brain tumor",true,"ALL","18 Years","80 Years",{"count":21,"type":22},28,"ESTIMATED","OBSERVATIONAL","Observational study:\n\nThe goal of this observational study is to learn about the association between slow wave activity before awakening and post-awakening psychomotor vigilance task in time-fixed, 2-hour, simulated night naps in healthy individuals.\n\nThe main question aims to answer is:\n\nIs the quantity of slow wave activity immediately before awakening associated with post-awakening psychomotor vigilance task metrics when awakened after 2-hour nap at night?",[26,27,28],"Sleep, Slow-wave Sleep, Sleep Enhancement, Sleep Optimization","Sleep Inertia","Night Shift Work",[30,31],"sleep inertia","nap","NOT_YET_RECRUITING","2026-02-06",{"date":35,"type":36},"2026-02-13","ACTUAL",{"date":38,"type":22},"2026-02-04",{"date":40,"type":22},"2026-08-30",{"name":42,"class":43},"Mahidol University","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":44},"100572362","study-of-sleep-inertia-in-major-depressive-disorder-by-the-psychomotor-vigilance-task-100572362","NCT06732284","Study of Sleep Inertia in Major Depressive Disorder by the Psychomotor Vigilance Task","IN-DEP","Inclusion Criteria:\n\n* The patient must have given their free and informed consent and signed the consent form\n* The patient must be a member or beneficiary of a health insurance plan\n* Ability to understand, write and read French Inclusion criteria for patients with major depression\n* Diagnosis of depression according to DSM-5 criteria\n* Suspicion of a sleep disorder requiring polysomnographic screening\n* Score for IHSS items 3 and 4\n\n  * Score ≥ 1 for group with sleep inertia\n  * Score = 0 for the group without sleep inertia Inclusion criteria for controls\n* No complaints of sleep inertia (score = 0 on IHSS items 3 and 4)\n* No excessive daytime sleepiness (Epworth Sleepiness Scale score ≤10),\n* No depressive symptoms (Hospital Anxiety Depression Scale score \\\u003C 8 on items 2, 4, 6, 8, 10, 12, 14).\n\nExclusion Criteria:\n\n* The patient is participating in an interventional study\n* The patient is under safeguard of justice or state guardianship\n* Unweaned from the following medications for at least 5 half-lives prior to inclusion: wake-promoting or psychostimulant drugs (modafinil, methylphenidate, mazindol, amphetamine, pitolisant, solriamfetol, sodium oxybate), neuroleptics, hypnotics, antidepressants, anxiolytics, antiepileptics, budipine, dopamine agonist and antagonist antiemetics (except domperidone), opiates, gabapentin, pregabalin, benzodiazepines, Z-hypnotics (zolpidem and zopiclone), monoamine oxidase inhibitors, catechol-O-methyltransferase or sedative antihistamines.\n* Patients with central nervous system diseases: Parkinson's disease, mild cognitive impairment and dementia, progressive supranuclear palsy, multisystem atrophy, Huntington's chorea, amyotrophic lateral sclerosis, epilepsy, history of head trauma with loss of consciousness.\n* Patients with a malignant neoplastic disease requiring therapeutic treatment in the 12months prior to the screening visit\n* Other medical or psychiatric illnesses (with the exception of depression in he depression group) which, in the investigator's opinion, could interfere with the study.\n* History of suicide attempt (including failed attempt), or suicidal ideation in the past month\n* Chronic alcohol consumption or drug abuse in the previous 6 months\n* Sleep-wake circadian rhythm disorders and presence of sleep insufficiency according to ICSD-3 criteria\n* Pregnant, parturient or breast-feeding women.","54 Years",{"count":54,"type":22},110,"The study population comprises three groups of 30 analyzable participants: Patients with sleep inertia and Major Depressive Disorder, patients with Major Depressive Disorder but without sleep inertia, and controls without mood disorders or sleep inertia. Controls will be patients referred to the Sleep Disorders and Acupuncture Unit for polysomnography as part of the screening process for a sleep disorder. Only controls presenting an apnea-hypopnea index \\\u003C 15\u002Fh, a periodic leg movements index during sleep \\\u003C 15\u002Fh and a total sleep time ≥ 6 hours on the video-polysomnography will be analyzed.",[57,27],"Major Depression",[59],"psychomotor vigilance task","RECRUITING","2025-12-04",{"date":63,"type":36},"2025-12-11",{"date":65,"type":36},"2025-11-04",{"date":67,"type":22},"2027-03",{"name":69,"class":43},"Centre Hospitalier Universitaire de Nīmes"]