[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"soft-tissue-grafting\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:soft-tissue-grafting":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100638981","evaluating-the-barrier-function-regenerative-capacity-and-soft-tissue-outcomes-of-acellular-dermal-matrix-100638981",false,"NCT07613047","Evaluating the Barrier Function, Regenerative Capacity, and Soft Tissue Outcomes of Acellular Dermal Matrix","A Prospective, Double-Arm, Randomized Controlled Trial Evaluating the Barrier Function, Regenerative Capacity, and Soft Tissue Outcomes of Acellular Dermal Matrix Compared to Resorbable Collagen Membranes in Edentulous Ridge Augmentation","Inclusion Criteria:\n\n* English speaking\n* At least 18 years old\n* Must be a patient of the UAB Dental School\n* Able to read and understand informed consent document\n* Patients presenting with a diagnosed need horizontal ridge augmentation with GBR without simultaneous implant placement, to allow for future dental implant placement.\n* Presence of periodontally healthy, non-carious neighboring teeth and\u002For healthy restored dental implants on either side of the edentulous span planned for GBR, or unhealthy adjacent teeth to be extracted during the same visit.\n* ≤4 mm ridge width in a Seibert Class I Edentulous span19\n* No anticipated need for surgical and\u002For endodontic care at planned teeth adjacent to the proposed surgical site during the study period.\n\nExclusion Criteria:\n\n* Non-English speaking\n* Less than 18 years old\n* Smokers\u002Fnicotine users (defined as currently reporting use of any form of tobacco\u002Fnicotine products)\n* Patients with systemic pathologies or conditions contraindicating oral surgical procedures or adversely affecting wound healing, including:\n\n  * Uncontrolled diabetes (HbA1c \\> 7%)\n  * Untreated periodontal disease\n  * History of head\u002Fneck radiation\n  * IV bisphosphonates\n  * Immunocompromised state\n  * Pregnancy\n  * Acute infection at site\n* Documented or suspected allergy or sensitivity to any study product",true,"ALL","18 Years","85 Years",{"count":21,"type":22},70,"ESTIMATED","INTERVENTIONAL",[25],"NA","This investigator-initiated study will compare ADM and resorbable cross-linked collagen membrane barriers for guided bone regeneration at atrophic lateral ridge augmentation sites.",[28,29,30],"Acellular Dermal Matrix","Bone Grafting","Soft Tissue Grafting",[32],"soft tissue graft","NOT_YET_RECRUITING","2026-05-28",{"date":36,"type":37},"2026-06-01","ACTUAL",{"date":39,"type":22},"2026-10",{"date":41,"type":22},"2028-10",{"name":43,"class":44},"University of Alabama at Birmingham","OTHER"]