[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"soft-tissue\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:soft-tissue":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,69],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100641906","evaluation-of-multilayered-prf-in-comparison-with-connective-tissue-graft-by-sohn-ponchos-technique-on-peri-implant-mucosal-enhancement-in-the-esthetic-zone-100641906",false,"NCT07649239","Evaluation of Multilayered PRF in Comparison With Connective Tissue Graft by Sohn Poncho's Technique on Peri-implant Mucosal Enhancement in the Esthetic Zone","Evaluation of Multilayered PRF in Comparison With Connective Tissue Graft by Sohn Poncho's Technique on Peri-implant Mucosal Enhancement in the Esthetic Zone. A Randomized Clinical Trial","-Inclusion Criteria: Patients with single bounded missing tooth in the esthetic zone Patients in the age group of 21-65 years Patients having good oral hygiene (mean plaque score of \\\u003C 25%) and with stable periodontal status.\n\n-Exclusion Criteria: Smokers patients Patients with poor maintenance of oral hygiene, as determined by a mean plaque score of ≥ 25% despite efforts by the clinician to improve oral hygiene maintenance.\n\nPatients with medically compromised conditions like uncontrolled diabetes mellitus or any systemic diseases that may result in compromised hard and soft tissue healing.",true,"ALL","20 Years","70 Years",{"count":21,"type":22},26,"ESTIMATED","INTERVENTIONAL",[25],"NA","An effective biological seal is crucial for protecting and supporting dental implants, particularly in the anterior region for the desired esthetic outcome.PRF membrane and CTG has been utilized to improve peri-implant soft tissue thickness and increase the width of keratinized tissue around dental implants. The stability of the PRF membrane is maintained by securing it with the healing abutment of the implant. While a few longitudinal studies have assessed the benefits of using PRF membrane with Sohn's Poncho technique in the posterior region, its effectiveness in the anterior region of the mouth remains to be evaluated.",[28,29,30,31,32],"Soft Tissue","Peri-Implant Health","Soft Tissue Augmentation at Dental Implants","Connective Tissue Graft","PRF","RECRUITING","2026-06-12",{"date":36,"type":37},"2026-06-16","ACTUAL",{"date":39,"type":37},"2026-01-10",{"date":41,"type":22},"2027-02-01",{"name":43,"class":44},"Gulf Medical University","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":4,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":45},"100320952","pediatric-petmr-image-registry-100320952","NCT03458520","Pediatric PET\u002FMR Image Registry","Inclusion Criteria:\n\n* Patients with proven solid tumors or newly diagnosed mass strongly suspected to represent a solid tumor.\n* We might also include some patients with leukemia if there is concern for a focal lesion in any of their organs.\n* Participant's parents (if participant is under 18) or the participant (if participant is 18 years or older) must willingly give written informed consent prior to any image transfer to the image registry.\n\nExclusion Criteria:\n\n* Patient has contraindications for MRI or PET\u002FMR. This includes patients with cardiac pacemakers or intracranial vascular clips as well as patients with a blood glucose level \\> 200 mg\u002Fdl.\n* Lack of parental permission (if participant is younger than 18) or lack of informed consent (if participant is at least 18 years of age).\n* Patient has a CNS primary tumor.\n* Pregnant women and fetuses","40 Years",{"count":54,"type":22},100,"OBSERVATIONAL","The purpose of this study is to compare whole body magnetic resonance (MR) imaging, whole body positron emission tomography (PET)\u002FMR imaging, and (if available) PET\u002FComputed Tomography (CT) imaging for the diagnosis of tumors in children and young adults. Sensitivities, specificities and diagnostic accuracies of the different imaging modalities will be compared for significant differences.",[28,58,59],"Lymphoma","Osteosarcoma","2026-02-05",{"date":62,"type":37},"2026-02-09",{"date":64,"type":37},"2018-02-01",{"date":66,"type":22},"2026-12-31",{"name":68,"class":44},"Stanford University",{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":17,"minAge":76,"maxAge":4,"enrollmentInfo":77,"targetDuration":4,"studyType":23,"phases":79,"briefSummary":81,"conditions":82,"keywords":86,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":45},"100622498","phase-4-application-of-topical-oxygen-therapy-around-customized-healing-collar-100622498","NCT07384403","Application of Topical Oxygen Therapy Around Customized Healing Collar","Evaluation of Linear and Volumetric Soft Tissue Changes Following the Application of Topical Oxygen Therapy Around Customized Healing Collars: Case Series","Inclusion Criteria:\n\n* Adults aged 21 years and above.\n\n  * Indicated for customized healing collar placement after second-stage surgery.\n  * Good general health.\n  * Able and willing to provide written informed consent.\n  * Committed to follow-up visits.\n\nExclusion Criteria:\n\n* Individuals below 21 years old.\n* Systemic diseases affecting healing.\n* Smokers\u002Ftobacco users.\n* Pregnant\u002Flactating women.\n* Medications affecting soft tissue healing.\n* Chemotherapy\u002Fradiotherapy patients.","21 Years",{"count":78,"type":22},6,[80],"PHASE4","The preservation and enhancement of peri-implant soft tissues are essential for the long-term success and esthetic integration of dental implants. Customized healing abutments have been introduced to support individualized soft tissue shaping; however, optimizing soft tissue healing around implants remains a clinical challenge. Oxygen plays a critical role in wound healing by promoting angiogenesis, fibroblast proliferation, and collagen synthesis. Topical oxygen therapy has shown promise in accelerating tissue regeneration, yet its application in oral implantology, particularly in conjunction with customized healing abutments, has not been adequately studied. This study aims to provide clinical evidence regarding the effectiveness of topical oxygen therapy in improving linear and volumetric soft tissue changes around dental implants. The findings may guide clinicians in refining soft tissue management protocols and contribute to establishing evidence-based practices in implant dentistry.",[28,83,84,85],"Healing Abutment Influence on Gingival Volume","Soft Tissue Healing","Dental Implant Healing",[87,88,89],"Oxygen gel","volumetic change of soft tissue","implant","2026-01-25",{"date":92,"type":37},"2026-02-03",{"date":94,"type":37},"2026-01-01",{"date":96,"type":22},"2026-09",{"name":98,"class":44},"Cairo University"]