[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"spatial-memory-disorder\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:spatial-memory-disorder":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100515462","sevoflurane-general-anesthetic-and-spatial-memory-in-humans-100515462",false,"NCT05991817","Sevoflurane General Anesthetic and Spatial Memory in Humans","Study of the Effect of Sevoflurane General Anesthetic on Spatial Memory in Humans","Inclusion Criteria:\n\n* Candidate for elective laparoscopic surgery of cholecystectomy.\n* Age 30 to 50 years.\n\nExclusion Criteria:\n\n* Visual or hearing difficulties.\n* Malignant hyperthermia.\n* Being treated with centrally acting drugs, such as anxiolytics, antidepressants, antipsychotics, anticonvulsants, anticholinergics, and first-generation antihistamines.\n* Present a disorder of the sphere of neuropsychiatry\n* Substance abuse disorder.","ALL","30 Years","50 Years",{"count":20,"type":21},22,"ESTIMATED","30 Days","OBSERVATIONAL","The goal of this observational study is to learn about the effect of general anesthetic on spatial memory in adults who will undergo to an elective surgery. The main question it aims to answer is:\n\n• A surgical event under general anesthesia with sevoflurane transiently impairs spatial memory in humans and induces an increase in inflammatory cytokines.\n\nParticipants will perform a virtual maze test and plasma samples will be taken before and after surgery.",[26],"Spatial Memory Disorder","RECRUITING","2025-11-17",{"date":30,"type":31},"2025-11-20","ACTUAL",{"date":33,"type":31},"2023-08-14",{"date":35,"type":21},"2025-12-30",{"name":37,"class":38},"University of Chile","OTHER",2]