[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"spatial-neglect\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:spatial-neglect":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,43,73,105],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100632871","dosing-and-deployment-trial-a-home-based-optokinetic-treatment-100632871",false,"NCT07519317","Dosing and Deployment Trial: A Home-based Optokinetic Treatment","Dosing and Deployment Trial: A Home-based Optokinetic Treatment for Ipsilesional Gaze Deviation","Inclusion Criteria for stroke group:\n\n1. first and unilateral right brain damage stroke, confirmed by medical records,\n2. time post stroke \\>6 months,\n3. moderate to severe SN, classified using the Catherine Bergego Scale (CBS) via the Kessler Foundation Neglect Assessment Process (KF-NAP),\n4. over age of 60 years, and\n5. IGD noted either on the KF-NAP or neuroimaging from medical records.\n\nExclusion Criteria for stroke group:\n\n1. history of multiple strokes or neurological incidents (e.g., traumatic brain injury, seizures, or brain tumor),\n2. unable to communicate through spoken English, screened using the Aphasia Rapid Test (ART), as instructions for treatment and assessment tasks will be provided verbally in English,\n3. cognitive impairment as defined by the Blind-MoCA,\n4. dependent in mobility- walking or wheelchair via medial chart,\n5. legally blind per medical chart,\n6. home located out of a 50-mile radius from Duke University, making it too costly for the frequent home visits, and\n7. no IGD present.\n\nInclusion Criteria for caregiver group:\n\n1. a current care partner (defined as someone providing care and assistance) of a stroke survivor living with SN,\n2. English speaker,\n3. the stroke survivor they are caring for has been enrolled into the study.\n\nExclusion Criteria for caregiver group:\n\n1. not a care partner currently,\n2. can't speak English,\n3. the stroke survivor didn't consent",true,"ALL","60 Years","110 Years",{"count":21,"type":22},90,"ESTIMATED","INTERVENTIONAL",[25],"NA","Several interventions exist for remediation of spatial neglect, but they have mixed evidence. Optokinetic stimulation is a bottom-up intervention; in other words, it is a stimulus-driven process, with Level A (strongest) evidence, and is recommended in clinical practice guidelines such as the American Heart Association's stroke guidelines. The studies currently published all use varing doses (number of sessions a week), did not assess the impact on mobility and risk of falls, and have not been implemented in the home setting. It is imperative to understand how to successfully implement this intervention at home, and learn how it will impact mobility in order to better support a large population of individuals living with chronic spatial neglect and who face barriers to accessing care because they require caregiver support to leave the home. This will be done using both qualitative and quantitative methods.",[28],"Spatial Neglect",[30],"spatial neglect; optokinetic stimulation; stroke","NOT_YET_RECRUITING","2026-06-22",{"date":34,"type":35},"2026-06-25","ACTUAL",{"date":37,"type":22},"2027-01-04",{"date":39,"type":22},"2028-06-16",{"name":41,"class":42},"Duke University","OTHER",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":16,"sex":17,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":23,"phases":54,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":72},"100520188","spatial-motor-stroke-rehab-study-100520188","NCT06053320","Spatial-Motor Stroke-Rehab Study","Novel Spatial-Motor Approaches to Improve Spatial Neglect and Walking Deficits Post-Stroke","Inclusion Criteria:\n\nYoung Adults Able Bodied (YAB) Individuals\n\n* 18-30 years\n* Able-Bodied (healthy without any physical disability or neurological disorder)\n\nOlder Adults Able-Bodied Individuals (OAB)\n\n* 45-90 years\n* Able-Bodied (healthy without any physical disability or neurological disorder)\n\nIndividuals with right hemisphere stroke (40-90 years)\n\n* \\>3 months following stroke.\n* Presence of Aiming SN\n* Ability to walk \\>10m with or without assistive devices.\n* Unilateral left-sided hemiparesis with gross arm strength of ≤ grade 4\u002F5 on the Medical Research Council Scale\n* Ability to follow 3-stage commands and provide informed consent.\n\nExclusion Criteria:\n\nYoung Adults Able-Bodied (YAB) Individuals and Older Adults Able-Bodied Individuals (OAB)\n\n* History or evidence of orthopedic or physical disability\n* History or evidence of neurological pathology\n* Pregnancy (female)\n* Uncontrolled hypertension\n* Cardiac pacemaker or other implanted electronic system\n* Presence of skin conditions preventing the electrical stimulation setup\n* Impaired sensation in the left upper limb.\n* Bruises or cuts at the stimulation electrode placement site\n* Concurrent enrollment in rehabilitation or another investigational study.\n* History or evidence of orthopedic or physical disability interfering with study procedures\n* History or evidence of neurological pathology or disorder\n* Severe uncontrolled medical problems (e.g., hypertension, cardiovascular disease, rheumatoid arthritis, active cancer or renal disease, epilepsy) that may interfere with study procedures\n* Contraindications to TMS, such as metal implants, medications that can increase cortical excitability, and unexplained dizziness in the past 6 months\n\nIndividuals with right hemisphere stroke (40-90 years)\n\n* History or brainstem strokes\n* Cerebellar disorders\n* Impaired sensation in the left upper limb.\n* History of other neurological disorders\n* Uncontrolled hypertension\n* Cardiac pacemaker or other implanted electronic system\n* Pregnancy (female)\n* Presence of skin condition\n* Bruises at the electrode placement site\n* Severe uncontrolled medical problems (e.g., hypertension, cardiovascular disease, rheumatoid arthritis, active cancer or renal disease, epilepsy) or other medical conditions that can interfere with study procedures\n* Contraindications to TMS, such as metal implants in the brain, medications that will increase cortical excitability, etc.","18 Years","90 Years",{"count":53,"type":22},65,[25],"The purpose of this study is to understand how prism adaptation training with and without electrical stimulation changes visuospatial behavior, motor system neurophysiology, and walking dysfunction.",[28,57],"Stroke",[59,60,61],"Post-stroke","Prism Adaptation Therapy (PAT)","Walking","RECRUITING","2026-05-18",{"date":65,"type":35},"2026-05-20",{"date":67,"type":35},"2023-04-11",{"date":69,"type":22},"2026-09",{"name":71,"class":42},"Emory University",3,{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":16,"sex":17,"minAge":50,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":83,"phases":4,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":104},"100634314","validation-of-web-based-star-cancellation-and-line-bisection-tests-in-hemiplegic-stroke-100634314","NCT07538076","Validation of Web-Based Star Cancellation and Line Bisection Tests in Hemiplegic Stroke","Development and Validity of Web Based Star Cancellation Test and Line Bisection Test in the Assessment of Visuospatial Neglect in Hemiplegic Stroke Patients","Inclusion Criteria:\n\n* Age 18 to 80 years\n* First-ever ischemic or hemorrhagic stroke\n* Hemiplegia secondary to stroke\n* Stroke in the subacute or chronic phase, defined as 1 to 24 months after stroke onset\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* History of neurological or severe psychiatric disease before stroke that could significantly affect cognitive function or attention, such as brain tumor, traumatic brain injury, vasculitis, multiple sclerosis, or schizophrenia\n* Severe visual field defect not attributable to visuospatial neglect, such as isolated homonymous hemianopia\n* Severe upper extremity motor impairment or apraxia preventing interaction with the tablet or stylus pen\n* Inability to understand test instructions, cooperate with the assessment, or complete the evaluation process","80 Years",{"count":82,"type":22},105,"OBSERVATIONAL","The goal of this observational study is to evaluate the clinical usability and diagnostic performance of newly developed web-based Star Cancellation and Line Bisection tests in assessing visuospatial neglect in hemiplegic stroke patients. It will also compare these digital tests with conventional paper-and-pencil assessments.\n\nThe main questions it aims to answer are:\n\nCan the web-based Star Cancellation and Line Bisection tests accurately distinguish between stroke patients with and without visuospatial neglect? Do digital test parameters (such as completion time, search speed, and search patterns) provide additional clinical information beyond conventional test scores? Researchers will compare the results of the web-based tests with standard paper-and-pencil tests to evaluate their diagnostic accuracy and clinical validity.\n\nParticipants will:\n\nComplete conventional paper-and-pencil Star Cancellation and Line Bisection tests Perform web-based (digital) versions of the same tests using a tablet and stylus Undergo routine clinical and cognitive assessments as part of standard care Provide demographic and clinical information",[57,28,86],"Spatial Neglect After Stroke",[88,28,89,90,91,92,93,94],"Visuospatial Neglect","Stroke Rehabilitation","Digital Assessment","Web-Based Assessment","Star Cancellation Test","Line Bisection Test","Neuropsychological Testing","2026-04-12",{"date":97,"type":35},"2026-04-20",{"date":99,"type":22},"2026-04-15",{"date":101,"type":22},"2026-12-01",{"name":103,"class":42},"Istanbul Medeniyet University",1,{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":111,"eligibilityCriteria":112,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":113,"targetDuration":4,"studyType":23,"phases":115,"briefSummary":116,"conditions":117,"keywords":118,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":5},"100485023","engaging-mobile-prism-adaptation-treatment-at-home-100485023","NCT05595668","Engaging Mobile Prism Adaptation Treatment at Home","Feasibility and Effectiveness of a New Computerized Treatment Protocol for Spatial Neglect Post Stroke During Inpatient and Outpatient Rehabilitation","EMPATH","Inclusion Criteria:\n\n1. Have experienced a right hemisphere stroke (confirmed by a clinician)\n2. Experience mild to severe symptoms of neglect\n3. Be willing and able to consent to participate\n4. Be medically stable\n5. Have self-reported normal to corrected-to-normal vision\n6. Be able to point to targets presented on a computer screen\n7. Live within a two-hour radius of Halifax\n\nExclusion Criteria:\n\nOther existing neurological disorders (e.g., dementia, multiple sclerosis, epilepsy).",{"count":114,"type":22},80,[25],"Spatial neglect is a common disorder after stroke which leads to problems with noticing or responding to information from the left side of the body or space. This condition has been linked to reduced independence in a wide range of daily life activities including eating, dressing, and mobility. Despite its high prevalence in stroke patients, there is currently no standard of care for spatial neglect. Prism adaptation (PA) is a promising treatment, however, there are limitations to using PA in standard clinical care as it requires daily exposure for at least two weeks, yet access to equipment and supervision is limited. To solve this problem, the investigators have developed a new game-like PA treatment (Peg-the-Mole, PTM) that can be used at home without the need for daily in person therapist set-up and supervision. In this study the investigators aim to evaluate the feasibility and effectiveness of the gamified and portable PA procedure in an inpatient and home setting, with the hypothesis that the PA procedure will improve patient's neglect symptoms.",[28],[28,119,120,57],"Prism Adaptation","Rehabilitation","2025-07-25",{"date":123,"type":35},"2025-07-30",{"date":125,"type":35},"2023-09-15",{"date":127,"type":22},"2026-11",{"name":129,"class":42},"Nova Scotia Health Authority"]