[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"speech-disorders-in-children\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:speech-disorders-in-children":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,51,81,103],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":33,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100555444","measuring-aided-language-development-100555444",false,"NCT06512168","Measuring Aided Language Development","MALD","Inclusion Criteria:\n\n* Clinical Identification of Down Syndrome or Cerebral Palsy + Significant Speech Impairment\n* Must Speak English as a Primary Language\n* Must Be Able to Express At Least 25 Words (using any communication mode)\n* Must Be Able to Accurately Select Picture Symbols on iPad Communication App with at Least 50% Accuracy\n* Vision and Hearing within Functional Limits or Corrected to be within Functional Limits for Study Activities\n\nExclusion Criteria:\n\n* Clinical Diagnosis of Autism or Social Communication Disorder\n* Primary Language Spoken is A Language Other than English","ALL","42 Months","60 Months",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","The focus of the current study is to systematically investigate the psychometric properties of a range of aided language measures, which are based on the Graphic Symbol Utterance and Sentence Development Framework (Binger \\& Kent-Walsh).",[27,28,29,30,31,32],"Down Syndrome","Cerebral Palsy","Apraxia of Speech","Speech Sound Disorder","Speech Disorders in Children","Speech and Language Disorder",[34,35,36,37],"Augmentative and Alternative Communication","Complex Communication Needs","Assistive Technology","AAC","RECRUITING","2025-05-13",{"date":41,"type":42},"2025-05-16","ACTUAL",{"date":44,"type":42},"2025-04-01",{"date":46,"type":21},"2028-03-31",{"name":48,"class":49},"University of Central Florida","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":16,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":61,"studyType":62,"phases":4,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":50},"100584902","high-and-low-intensity-speech-intervention-in-children-with-a-cleft-palate-perceptions-of-children-their-caregivers-and-speech-language-pathologists-100584902","NCT06895395","High and Low Intensity Speech Intervention in Children With a Cleft Palate: Perceptions of Children, Their Caregivers and Speech-language Pathologists","Inclusion Criteria:\n\n* Belgian Dutch-speaking children with a cleft palate with or without a cleft lip\n* Aged between 4 and 12 years,\n* Presence of at least one compensatory speech error in their speech based on the perceptual assessment of one experienced speech-language pathologist\n\nExclusion Criteria:\n\n* Children with syndromic clefts\n* Oronasal fistula\n* Velopharyngeal insufficiency\n* Hearing disabilities based on pure tone audiometry (\\>25 dB HL)\n* Cognitive and\u002For related learning disabilities or neuromuscular disorders","4 Years","12 Years",{"count":60,"type":21},175,"1 Month","OBSERVATIONAL","A cleft (lip and) palate (CP±L) is the most common congenital abnormality of the face and skull with a significant social impact, affecting speech, hearing, feeding, oral behavior, dentition and satisfaction with appearance. These consequences have a long-term and negative impact on social integration and well-being. The World Health Organization (WHO) highlights the significant financial costs, including morbidity, health care costs, emotional distress and social exclusion for patients, their families and society. The purpose of this study is to compare high- and low-intensity speech intervention in children with CP±L based on the perceptions of the providers of the intervention (primary care speech-language pathologists) and the recipients of the intervention (children with CP±L and their caregivers). Individual semi-structured interviews will be conducted with both intervention providers and recipients to explore perceptions and experiences, as well as acceptability of the two speech intervention intensities. Potential participants will be told that the interview will be recorded. The actual interviews will take place at a location and time that is most convenient for the participants. Each interview will be recorded using a Roland R-05 high-quality audio recorder. After conducting the interviews, all participants will be asked to complete a questionnaire regarding their demographics. In addition, data regarding the type of cleft, time and manner of closure of the cleft, any secondary surgery and otological\u002Faudiological data will be collected from the medical records of the children with CP±L. Based on this qualitative study, possible adjustments to the high-intensity therapy protocol can be made. In doing so, these modifications will be relevant to these key stakeholders. This will also facilitate the implementation and widespread use of high-intensity speech therapy in clinical speech therapy practice.",[65,31],"Cleft Lip and Palate",[67,68,69,70,71],"Cleft lip and palate","Qualitative research","Speech therapy","Interviews","Speech intervention intensity","2025-03-25",{"date":74,"type":42},"2025-03-26",{"date":76,"type":21},"2025-05-01",{"date":78,"type":21},"2027-12",{"name":80,"class":49},"University Ghent",{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":16,"minAge":57,"maxAge":58,"enrollmentInfo":87,"targetDuration":4,"studyType":22,"phases":89,"briefSummary":90,"conditions":91,"keywords":94,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":102,"locationsCount":50},"100545423","effect-and-cost-utility-of-of-high-intensity-vs-low-intensity-speech-intervention-in-children-with-cleft-palate-100545423","NCT06381713","Effect and Cost-utility of of High Intensity vs. Low Intensity Speech Intervention in Children With Cleft Palate","Short and Long Term Effect and Cost-utility of High Intensity vs. Low Intensity Speech Intervention in Children With Cleft Palate",{"count":88,"type":21},70,[24],"Achieving speech that is understandable and acceptable to others is the key outcome in cleft treatment. Therefore, speech therapy provided by a speech-language pathologist is necessary. This intervention is traditionally provided twice per week for 30 minutes for months or even years by first-line speech-language pathologists. Unfortunately, this low intensity intervention is based on a historical context rather than scientific evidence. This means that current speech therapy knows several shortcomings including poor outcomes, treatment fatigue and high costs related to year-long therapy. Because of these issues, the use of high intensity speech intervention is proposed. Even though solid proof-of-concepts exist for this model, it has not yet found its way into clinical practice.\n\nBefore this intensity can be implemented and utilized in clinical practice, the effect of this novel program on a larger societal scale must be determined. This project will compare the effect of high intensity and low intensity speech intervention in children with a cleft palate in terms of speech, quality of life, and cost-utility as provided by first-line speech-language pathologists by conducting a large-scale randomized controlled trial. The final goal is to utilize this program in clinical practice and to create awareness of the benefits for children with a cleft palate among stakeholders.",[92,93,31,65],"Cleft Palate Children","Speech Therapy",[95,69,67],"Randomized controlled trial","2025-01-09",{"date":98,"type":42},"2025-01-13",{"date":100,"type":42},"2024-11-26",{"date":78,"type":21},{"name":80,"class":49},{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":11,"sex":16,"minAge":57,"maxAge":58,"enrollmentInfo":110,"targetDuration":4,"studyType":22,"phases":112,"briefSummary":113,"conditions":114,"keywords":115,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":50},"100524159","effect-of-performance-specific-cleft-speech-intervention-and-long-term-learning-in-children-with-a-cleft-palate-100524159","NCT06105099","Effect of Performance-specific Cleft Speech Intervention and Long-term Learning in Children With a Cleft Palate","One Size Does Not Fit All: From a Common Approach Towards Performance-specific Speech Intervention and Long-term Learning in Children With a Cleft Palate","Inclusion Criteria:\n\n* Belgian Dutch-speaking children with a cleft palate with or without a cleft lip\n* Aged between 4 and 12 years\n* Presence of at least one compensatory speech error in their speech based on the perceptual assessment of one experienced speech-language pathologist\n\nExclusion Criteria:\n\n* Children with syndromic clefts\n* Oronasal fistula\n* Velopharyngeal insufficiency\n* Hearing disabilities based on pure tone audiometry (\\>25 dB HL)\n* Cognitive and\u002For related learning disabilities or neuromuscular disorders",{"count":111,"type":21},135,[24],"Speech therapy in children with a palate deals with two scientific challenges that will be addressed in this project.\n\nThe first challenge is selecting the best speech approach for a child with a specific cleft speech characteristic (CSC). Many speech therapists use a 'one-size-fits-all' approach to treat compensatory CSCs resulting in poor short- and long-term speech outcomes. To increase the effectiveness and quality of cleft speech care, it is necessary to find the best match between a specific therapy and a given type of CSC. Therefore, this proposal will compare the effect of 3 different speech approaches on the speech and quality of life in Dutch speaking children with different types of CSCs.\n\nThe second challenge is selecting the best speech approach to enhance long-term learning and transfer of newly established speech skills to untrained consonants. To date, research mainly focused on immediate therapy effects. It is unknown if permanent speech changes occur. Hence, this project will also investigate the short-term and long-term learning effects (retention and transfer) of the different speech approaches from the first objective.\n\nThis proposal will improve evidence-based and patient-tailored cleft speech therapy.",[92,31,65,93],[95,69,67],"2023-10-23",{"date":118,"type":42},"2023-10-27",{"date":120,"type":42},"2022-10-01",{"date":122,"type":21},"2026-09-30",{"name":80,"class":49}]