[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"speech-sound-disorder\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:speech-sound-disorder":34},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,15,0,[8,54,89,118,146,178,200,220,245,269,295,320,345,369,391],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":36,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":53},"100371514","orthognathic-speech-pathology-phonetic-contrasts-of-patients-with-dental-discrepancies-pre--and-post-treatment-analyses-100371514",false,"NCT04117360","Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses","Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dentofacial Discrepancies With Pre- and Post-Treatment Analyses","OSP","Inclusion Criteria:\n\n* Jaw surgery patient at UNC with a skeletal open bite, underbite or overjet greater than 5mm.\n* Age 15-40 years\n\nExclusion Criteria:\n\n* Hearing loss\n* Learned English as a second language\n* Significant regional accent, as characterized by a speech pathologist\n* Developmental delay, performing several grade levels below age bracket\n* history of craniofacial disorder\n* genetic syndrome associated with known craniofacial presentation\n* history of craniofacial trauma\n* history of prior craniofacial surgery (excluding extractions and dental procedures)\n* Jaw surgery without fixed orthodontic appliances","ALL","15 Years","40 Years",{"count":21,"type":22},180,"ESTIMATED","OBSERVATIONAL","The investigators are studying how speech is effected by jaw and tooth position in jaw surgery patients. Eighty percent of our jaw surgery patients have speech pathologies, compared to five percent of the general population, but speech pathologists do not understand why. The investigators hypothesize that open bites and underbites prevent most patients from being able to pronounce words normally and surgical correction will lead to improvement in speech. Patients will be audio recorded speaking and patients' tongue gestures ultrasound recorded before and after their jaw surgeries to observe what changes occur in their speech and tongue movements.",[26,27,28,29,30,31,32,33,34,35],"Dentofacial Abnormalities","Dentofacial Deformities","Dentofacial Anomalies, Including Malocclusion","Malocclusion","Malocclusion in Children","Dentofacial Disharmony","Skeletal Malocclusion","Skeletal Malformation","Speech Sound Disorder","Speech Disorders",[31,37,34,38,39,40],"Skeletal malocclusion","Spectral Moment Analysis","Tongue Ultrasound","Orthognathic Surgery","RECRUITING","2026-06-10",{"date":44,"type":45},"2026-06-12","ACTUAL",{"date":47,"type":45},"2019-09-11",{"date":49,"type":22},"2028-03",{"name":51,"class":52},"University of North Carolina, Chapel Hill","OTHER",1,{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":4,"eligibilityCriteria":60,"healthyVolunteers":11,"sex":17,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":4,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":72,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":53},"100639774","exploratory-trial-of-the-hidongdong-language-rehabilitation-app-for-articulation-delay-100639774","NCT07613268","Exploratory Trial of the \"HiDongDong\" Language Rehabilitation App for Articulation Delay.","A Prospective, Single-center, Randomized Controlled, Open-Label, Assessor-Blinded, Investigator-Initiated Exploratory Clinical Trial of the Application-Based Language Rehabilitation Program \"HiDongDong\" for Improving Language Development in Children Suspected of Articulation and Phonological Delay","Inclusion Criteria:\n\n1. Children aged 2 years to under 14 years\n2. Persistent difficulties in speech sound production, or reduced speech intelligibility that interferes with communicative participation, resulting in limitations in social participation, academic performance, or daily activities\n3. Articulation developmental delay suspected based on U-TAP results, with articulation performance more than 1 standard deviation below the mean for the same age group (-1SD)\n4. Sufficient cognitive ability to follow simple instructions via a mobile device (tablet)\n5. For children under 7 years of age: a caregiver who has received sufficient explanation of the study purpose and procedures and has voluntarily provided written informed consent\n6. For children aged 7 years or older: voluntary assent from the child after sufficient explanation of the study purpose and procedures by the investigator,\n\nin addition to written informed consent from the caregiver\n\nExclusion Criteria:\n\n1. Caregiver or child does not consent to study participation, or withdraws consent during the study\n2. U-TAP results indicate articulation development within the normal range, with no suspicion of articulation developmental delay\n3. Difficulty understanding simple instructions or participating in assessments and training due to moderate or severe cognitive impairment, attention deficit, autism spectrum disorder, or similar conditions\n4. Significantly limited speech production due to neuromuscular or anatomical causes, including severe visual impairment or visual field deficits, hearing impairment, cleft palate structural abnormalities, or severe oral\u002Ffacial muscle dysfunction, resulting in difficulty with articulation\n5. Inability to continue study participation due to acute illness or other conditions that may affect assessment or training during the study period, or unwillingness of the caregiver or child to continue participation\n6. Determination by the principal investigator that study participation may pose a risk to the safety or well-being of the child\n\nAny one of the above exclusion criteria is sufficient for exclusion.","2 Years","13 Years",{"count":64,"type":22},48,"INTERVENTIONAL",[67],"NA","The purpose of this study is to evaluate the effectiveness of the AI-based application \"HiDongDong\" in improving articulation development in children aged 2 to under 14 years with suspected articulation delays. The program provides individualized language training based on a personalized assessment of vulnerable speech sounds. This trial aims to determine whether the digital therapeutic solution can enhance articulation skills and inform future strategies for language rehabilitation in children.",[34,70,71],"Language Development Disorders","Phonological Disorder",[73,74,75,76,77,78,34,70],"Phonological Delay","AI-based Therapy","Digital Therapeutic","Pediatric Speech Development","Application-Based Language Rehabilitation","Articulation Delay","NOT_YET_RECRUITING","2026-05-26",{"date":82,"type":45},"2026-05-29",{"date":84,"type":22},"2026-05",{"date":86,"type":22},"2026-08",{"name":88,"class":52},"Seoul National University Bundang Hospital",{"id":90,"slug":91,"hasResults":11,"nctId":92,"briefTitle":93,"officialTitle":94,"acronym":95,"eligibilityCriteria":96,"healthyVolunteers":11,"sex":17,"minAge":97,"maxAge":98,"enrollmentInfo":99,"targetDuration":4,"studyType":65,"phases":101,"briefSummary":103,"conditions":104,"keywords":105,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":117},"100584100","phase-2-generalization-with-ai-navigation-using-start-100584100","NCT06884943","Generalization With AI Navigation Using StaRt","Randomized Trial of AI-Enhanced Maintenance Training With Visual-Acoustic Biofeedback","GAINS","Inclusion Criteria:\n\n* • Must be between 9;0 and 17;11 (years;months) old at the time of enrollment.\n\n  * Must speak English as the dominant or equally dominant language\n  * Must have begun learning English by age 3, per parent report.\n  * Must hear a rhotic dialect of English from at least one speaker in the home if the home language is English.\n  * Must pass a pure-tone hearing screening.\n  * Must pass a brief examination of oral structure and function.\n  * Must demonstrate age-appropriate receptive and expressive language abilities on the Clinical Evaluation of Language Fundamentals-5 (CELF-5).\n  * Must have access to a laptop or desktop computer for study sessions.\n  * Must have home wifi sufficient to support video calls in the event of randomization to the telepractice condition.\n  * Must have completed participation in the VISIT randomized controlled trial.\n  * Must score at least 60% correct in at least one treatment session during the related previous study, VISIT.\n\nExclusion Criteria:\n\n* • Must not exhibit voice or fluency disorder of a severity judged likely to interfere with the ability to participate in study activities.\n\n  * Must not currently have orthodontia that crosses the palate and cannot be removed.\n  * Must not have history of permanent hearing loss.\n  * Must not have an existing diagnosis of developmental disability such as cerebral palsy or Down Syndrome.\n  * Must not have history of major brain injury, surgery, or stroke in the past year.\n  * Must not have epilepsy with active seizure incidents with in the past 6 months.\n  * Must not show clinically significant signs of apraxia of speech or dysarthria.","9 Years","17 Years",{"count":100,"type":22},76,[102],"PHASE2","Speech Sound Disorder (SSD) affects a significant portion of school-aged children, leading to social and emotional challenges that can persist into adolescence and adulthood. The number of productions necessary for a remediated speech sound to generalize to connected speech is challenging to achieve in practice, leading clinicians to call for accessible, reliable resources allowing children to continue therapy outside of direct clinical interactions. Artificial intelligence (AI) tools hold promise as a means to extend direct service delivery in speech-language pathology, but research investigating the topic has been limited. This study (Generalization with AI Navigation using staRt, or GAINS) will measure the effects of a course of AI-mediated home practice intended to promote generalization of gains made through biofeedback treatment in a related study, Visual-acoustic Intervention with Service Delivery In-person and Via Telepractice Trial (VISIT; NCT06517225).",[34],[106,107],"speech","articulation","2026-05-11",{"date":110,"type":45},"2026-05-13",{"date":112,"type":45},"2024-12-18",{"date":114,"type":22},"2029-07-01",{"name":116,"class":52},"New York University",2,{"id":119,"slug":120,"hasResults":11,"nctId":121,"briefTitle":122,"officialTitle":123,"acronym":4,"eligibilityCriteria":124,"healthyVolunteers":11,"sex":17,"minAge":125,"maxAge":126,"enrollmentInfo":127,"targetDuration":4,"studyType":65,"phases":129,"briefSummary":130,"conditions":131,"keywords":132,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":137,"lastUpdatePostDateStruct":138,"startDateStruct":140,"completionDateStruct":142,"leadSponsor":144,"locationsCount":53},"100579984","effectiveness-of-ultrasound-aided-articulation-therapy-for-children-with-speech-sound-disorders-100579984","NCT06831396","Effectiveness of Ultrasound-Aided Articulation Therapy for Children With Speech Sound Disorders","Communication in Children With or Without Biomedical Conditions: Speech and Language Profile, Related Outcomes and Articulation Treatment With Ultrasound","Inclusion Criteria:\n\n* Primary diagnosis of speech sound disorder with errors on lingual target sounds\n* Probe accuracy \\\u003C70% on the primary target sound at baseline\n* Cantonese as the first language\n* Hearing thresholds ≤25 dB in at least one ear, with no hearing loss exceeding 50 dB in the other ear\n* No syndromes or obvious dysmorphic features\n* No language disorders associated with biomedical conditions (e.g., cerebral palsy, autism spectrum disorder)\n* No oronasal fistula identified on oral examination or diagnosed velopharyngeal insufficiency\n\nExclusion Criteria:\n\n* Presence of syndromes or dysmorphic features\n* Language disorder associated with biomedical conditions (e.g., cerebral palsy, autism spectrum disorder)\n* Hearing thresholds \\>25 dB in one ear and \\>50 dB in the other ear Planned surgical intervention during the study period","5 Years","12 Years",{"count":128,"type":22},60,[67],"This prospective randomized controlled trial investigates the effect of ultrasound visual biofeedback as an adjunct to articulation therapy in children with speech sound disorders involving lingual targets. The intervention aims to facilitate acquisition of misarticulated sounds by providing real-time visualization of tongue movements. Participants are randomized 1:1 to immediate treatment or wait-list control, with stratification by disorder type, age, and gender where feasible. The wait-list control group continues usual care for 4 weeks before crossing over to receive the same intervention (ethical crossover design).",[34],[133,134,135,136],"Speech and Language","Children","Treatment","Ultrasound","2026-03-07",{"date":139,"type":45},"2026-03-10",{"date":141,"type":45},"2023-11-11",{"date":143,"type":22},"2026-10-30",{"name":145,"class":52},"The University of Hong Kong",{"id":147,"slug":148,"hasResults":11,"nctId":149,"briefTitle":150,"officialTitle":151,"acronym":4,"eligibilityCriteria":152,"healthyVolunteers":11,"sex":17,"minAge":125,"maxAge":153,"enrollmentInfo":154,"targetDuration":4,"studyType":65,"phases":156,"briefSummary":157,"conditions":158,"keywords":160,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":169,"lastUpdatePostDateStruct":170,"startDateStruct":172,"completionDateStruct":174,"leadSponsor":176,"locationsCount":53},"100626341","speech-intervention-via-telepractice-for-children-with-repaired-cleft-palate-100626341","NCT07434375","Speech Intervention Via Telepractice for Children With Repaired Cleft Palate","Speech Intervention Via Telepractice for Children With Repaired Cleft Palate: Randomized Controlled Trial and Assessment of Speech Production and Perception Skills","Inclusion Criteria:\n\n* Within the ages 5;0 and 11;11 (years; months) at enrollment and for enrollment duration\n* Having normal hearing based on a pure-tone hearing screening at 20 dB HL bilaterally at 500, 1000, 2000 and 4000Hz. Children with a history of hearing loss or children who currently are properly equipped with amplification will be included if they pass the hearing screening\n* Having typical nonverbal IQ, language, and socioemotional function as determined by a T-score with no more than -1.5 SD from the mean on Kauffman Brief Intelligence Test-2 (KBIT-2), receptive language of Clinical Evaluation Language Fundamentals-5 (CELF-5 Core Language), and Childhood Autism Rating Scale-2 (CARS-2)\n* Having a speech sound disorder as determined by a score ≤ 30th percentile on the Goldman-Fristoe Test of Articulation-3 (GFTA-3)\n* Demonstrate a cleft-related or a phonological error on at least one phoneme. For the sound, a cleft-related or a phonological error appears at word-initial phoneme on any two of the following tests; single words on GFTA-3, American English Phrase Samples (AEPS) and Sentence Sample (AESS) on the CAPS-A AM\n* Willing to comply with all study procedures and availability for the study duration.\n\nExclusion Criteria:\n\n* Demonstrates a medically diagnosed sensory or neurological disorder based on parents' report\n* Presents with velopharyngeal insufficiency (VPI) due to structural anomalies or an oronasal fistula\n* English is not the primary language spoken at home. Bilingual children will not be excluded.\n* Children who do not demonstrate cleft speech characteristics.","11 Years",{"count":155,"type":22},64,[67],"The goal of this interventional study is to see if online speech therapy works just as well as face-to-face speech therapy in children with cleft palate. The main purposes are:\n\nTo compare the speech accuracy of target sounds in words produced by children with cleft palate between online and face-to-face speech therapy.\n\nTo compare the gain in speech accuracy in sentences produced by children with cleft palate between online and face-to-face speech therapy.\n\nTo assess whether changes in speech intelligibility are perceived by parents. To explore what kinds of factors influence speech accuracy. To explore speech training accuracy and speech understandability training accuracy during speech therapy sessions in children with CP\n\nParticipants will participate in 30-minute speech intervention sessions twice a week for 10 weeks, either in-person or online.",[159,34],"Cleft Palate Children",[161,162,163,164,165,166,167,168],"non-inferiority","telepractice","speech therapy","intervention","speech perception","speech production","cleft palate","children","2026-02-25",{"date":171,"type":45},"2026-02-27",{"date":173,"type":22},"2026-03-02",{"date":175,"type":22},"2029-01-01",{"name":177,"class":52},"Texas Tech University Health Sciences Center",{"id":179,"slug":180,"hasResults":11,"nctId":181,"briefTitle":182,"officialTitle":182,"acronym":183,"eligibilityCriteria":184,"healthyVolunteers":11,"sex":17,"minAge":97,"maxAge":98,"enrollmentInfo":185,"targetDuration":4,"studyType":65,"phases":187,"briefSummary":189,"conditions":190,"keywords":4,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":191,"lastUpdatePostDateStruct":192,"startDateStruct":194,"completionDateStruct":196,"leadSponsor":198,"locationsCount":53},"100510701","phase-1-intensive-speech-motor-chaining-treatment-for-residual-speech-sound-disorders-100510701","NCT05929859","Intensive Speech Motor Chaining Treatment for Residual Speech Sound Disorders","iChain","Inclusion Criteria:\n\n* Must speak American English as a dominant language.\n* Must have began learning English by at least the age of 3 years.\n* Must be between 9;0 to 17;11 years of age.\n* Must have reported difficulty with \u002Fɹ\u002F and\u002For \u002Fs\u002F production\n* Must pass pure tone hearing screening at 25 dB at 1000, 2000, and 4000 Hz.\n* Must receive a scaled score of at least 5 on the Listening Comprehension and Story Retelling subtests of the Test of Integrated Language and Literacy Skills (TILLS)\n* Must receive a percentile score of 5 or below on the Goldman-Fristoe Test of Articulation-3 (GFTA-3) Sounds in Words subtest.\n* Must have 1 scorable response with 5+ consecutive correct \u002Fpataka\u002F with \\> 3.4 syllables per second in the MRR-Tri task of the Maximum Performance Tasks OR must demonstrate no childhood apraxia of speech (CAS-only) features in BOTH articulatory and rate\u002Fprosody domains of the ProCAD.\n* Must score \\\u003C40% accurate on \u002Fɹ\u002F and\u002For \u002Fs\u002F probes assessing these sounds at the word level.\n* Must express a desire to modify their speech.\n\nExclusion Criteria:\n\n* Must have no known history of autism spectrum disorder, Down Syndrome, cerebral palsy, intellectual disability, permanent hearing loss, or brain injury.\n* Must not have current cleft palate or voice disorder.",{"count":186,"type":22},84,[188,102],"PHASE1","The goal of this randomized-controlled trial is to compare distributed treatment schedules and intensive treatment schedules in 84 school-age children with residual speech sound disorders. The main question it aims to answer is:\n\n* How does intensive and distributed treatment affect speech sound learning in residual speech sound disorder?\n\nSome participants will be treated with a traditional Distributed schedule of 2 sessions per weeks for 8 weeks (16 hours total), whereas others will be treated with an Intensive schedule and will complete 16 hours of treatment in 4 weeks.",[34],"2026-01-12",{"date":193,"type":45},"2026-01-13",{"date":195,"type":45},"2023-10-26",{"date":197,"type":22},"2028-02-29",{"name":199,"class":52},"Syracuse University",{"id":201,"slug":202,"hasResults":11,"nctId":203,"briefTitle":204,"officialTitle":204,"acronym":4,"eligibilityCriteria":205,"healthyVolunteers":206,"sex":17,"minAge":97,"maxAge":98,"enrollmentInfo":207,"targetDuration":4,"studyType":65,"phases":209,"briefSummary":210,"conditions":211,"keywords":4,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":212,"lastUpdatePostDateStruct":213,"startDateStruct":215,"completionDateStruct":217,"leadSponsor":219,"locationsCount":53},"100515208","ai-assisted-treatment-for-residual-speech-sound-disorders-100515208","NCT05988515","AI-Assisted Treatment for Residual Speech Sound Disorders","Inclusion Criteria:\n\n* Must speak a rhotic dialect of American English as a dominant language.\n* Must have begun learning English by at least the age of 3 years.\n* Must be between 9;0 to 17;11 years of age.\n* Must have reported difficulty with \u002Fɹ\u002F production.\n* Must have reported hearing within normal limits.\n* Must receive a Scaled Score of 5 or above on both the Listening Comprehension and Story Retelling subtests from the Test of Integrated Language \\& Literacy Skills (TILLS).\n* Must receive a percentile score of 8 or below on the Goldman-Fristoe Test of Articulation-3 (GFTA-3) Sounds in Words subtest.\n* Must have 1 scorable response with 5+ consecutive correct \u002Fpataka\u002F with \\> 3.4 syllables per second in the MRR-Tri task of the Maximum Performance Tasks OR must demonstrate no childhood apraxia of speech (CAS-only) features in BOTH articulatory and rate\u002Fprosody domains of the ProCAD.\n* Must score \\\u003C40% accurate based on word-level items from our \u002Fɹ\u002F probe list.\n* Must score \\>=15% accuracy on \u002Fɹ\u002F on 45 syllables following Dynamic Assessment.\n* Must express interest in changing their \u002Fɹ\u002F production.\n* Must have oral structure and function that are appropriate for \u002Fɹ\u002F production.\n* Must have access to broadband internet with videoconferencing capabilities\n\nExclusion Criteria:\n\n* Must have no known history of autism spectrum disorder, Down Syndrome, cerebral palsy, intellectual disability, permanent hearing loss, epilepsy\u002Fantiepileptic medication, or brain injury\u002Fneurosurgery\u002Fstroke.\n* Must not have diagnosis of attention deficit disorder, attention deficit hyperactivity disorder, Tourette's, or Obsessive-compulsive disorder.\n* Must have no orthodontic appliances that block the roof of the mouth (e.g., palate expanders).\n* Must not have current cleft palate, fluency disorder, or voice disorder.\n* Must not demonstrate childhood apraxia of speech (CAS-only) features in BOTH articulatory and rate\u002Fprosody domains of the ProCAD.",true,{"count":208,"type":22},26,[67],"The goal of this randomized-controlled trial is to determine how artificial intelligence-assisted home practice may enhance speech learning of the \"r\" sound in school-age children with residual speech sound disorders. All child participants will receive 1 speech lesson per week, via telepractice, for 5 weeks with a human speech-language clinician. Some participants will receive 3 speech sessions per week with an Artificial Intelligence (AI)-clinician during the same 5 weeks as the human clinician sessions (CONCURRENT treatment order group), whereas others will receive 3 speech sessions per week with an AI-clinician after the human clinician sessions end (SEQUENTIAL treatment order group.",[34],"2026-01-07",{"date":214,"type":45},"2026-01-08",{"date":216,"type":45},"2024-09-05",{"date":218,"type":22},"2027-12-31",{"name":199,"class":52},{"id":221,"slug":222,"hasResults":11,"nctId":223,"briefTitle":224,"officialTitle":225,"acronym":4,"eligibilityCriteria":226,"healthyVolunteers":206,"sex":17,"minAge":227,"maxAge":228,"enrollmentInfo":229,"targetDuration":4,"studyType":65,"phases":231,"briefSummary":232,"conditions":233,"keywords":4,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":236,"lastUpdatePostDateStruct":237,"startDateStruct":239,"completionDateStruct":241,"leadSponsor":243,"locationsCount":117},"100405374","a-developmental-framework-for-linking-phonological-and-morpho-syntactic-sequential-pattern-rules-in-dld-production-100405374","NCT04558541","A Developmental Framework For Linking Phonological And Morpho-syntactic Sequential Pattern Rules In DLD: Production","A Developmental Framework For Linking Phonological And Morpho-syntactic Sequential Pattern Rules In Developmental Language Disorder: Production","Inclusion Criteria:\n\nBecause clinical precision is required, 4- to 8-year-olds will complete a large test battery.\n\n* All children (TD, DLD, DLD + SSD, SSD) will score above 75 on the Nonverbal Scale of the Kaufman Assessment Battery for Children (KABC-II), which is above the Diagnostic and Statistical Manual cut-off for intellectual disability, even considering the standard error of measurement.\n* Hearing will be within normal limits\n* Oral structures will be within normal limits (Robbins \\& Klee, 1987).\n* The Childhood Autism Rating Scale (Schopler et al., 2010) and parent report, will be used to rule out autism.\n\nChildren with DLD will meet standard criteria.\n\n* Children with DLD will score below the cutoff of 87 on the Structured Photographic Expressive Language Test-P2 (SPELT-P2; Dawson et al., 2005) that has demonstrated high diagnostic accuracy for DLD.\n* Children with DLD will perform below 80% in their spontaneous production of finite verb morphemes.\n* Performance on a nonword repetition task will also support DLD status. Scores below 70% for total phonemes correct across all nonword lengths are greater than 1 SD below the mean for typical children.\n* Speech production skills will be measured via the Goldman-Fristoe Test of Articulation-3 (GFTA-3; Goldman \\& Fristoe, 2015) and the inconsistency subtest of the Diagnostic Evaluation of Articulation and Phonology (DEAP, Dodd, et al., 2006). Many 4- to 6-year-old children with DLD are expected to perform below expected levels on the GFTA-3; for this study half of the children with DLD will show performance below expected levels and half above a standard score of 85. Children with SSD will show impaired performance on the GFTA-3, but typical performance on grammatically weighted language measures (SPELT-P2 and finite verb morphemes). The DEAP serves as a standardized measure of segmental inconsistency and will provide a post hoc analysis that may be related to sequence pattern variability.\n\nPerformance on the following measures will serve as covariates and will not be exclusionary for DLD or SSD:\n\n* Peabody Picture Vocabulary Test, 4th ed (Dunn \\& Dunn, 1997)\n* Expressive Vocabulary Test, 2nd ed (Williams, 1997)\n* Verbal and nonverbal memory span.\n* Because of the emphasis on English phonological and morpho-syntactic patterns, all participants will be monolingual English learners or report dominant exposure to English from infancy. Exposure to other languages will be documented.\n\nExclusion Criteria for all participants:\n\n* Hearing impairment\n* Intellectual impairment\n* Autism\n* Significant motor impairment.\n\nTypical participants will be excluded if they show:\n\n-Histories of developmental, speech, language, or hearing disorders.","4 Years","8 Years",{"count":230,"type":22},400,[67],"The broad aim of this clinical study is to assess the hypothesis that morphological and phonological deficits are linked by a broader deficit in sequential pattern learning. This hypothesis applies to learning in general, but is especially critical as an avenue for developing earlier assessments and more powerful interventions for children with developmental language disorder (DLD; also known as specific language impairment). Other populations, such as at-risk toddlers, may also benefit from this new approach.",[234,34,235],"Developmental Language Disorder","Specific Language Impairment","2025-10-24",{"date":238,"type":45},"2025-10-27",{"date":240,"type":45},"2022-08-07",{"date":242,"type":22},"2026-12-31",{"name":244,"class":52},"Father Flanagan's Boys' Home",{"id":246,"slug":247,"hasResults":11,"nctId":248,"briefTitle":249,"officialTitle":250,"acronym":251,"eligibilityCriteria":252,"healthyVolunteers":11,"sex":17,"minAge":253,"maxAge":153,"enrollmentInfo":254,"targetDuration":4,"studyType":65,"phases":256,"briefSummary":257,"conditions":258,"keywords":259,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":261,"lastUpdatePostDateStruct":262,"startDateStruct":264,"completionDateStruct":266,"leadSponsor":268,"locationsCount":53},"100609430","treatment-for-s-production-errors-in-children-with-speech-sound-errors-100609430","NCT07214480","Treatment for \u002Fs\u002F Production Errors in Children With Speech Sound Errors","An Alternative Service Delivery Model and Target Selection Approach for the Treatment of \u002Fs\u002F Errors","SPLITS-S","Inclusion Criteria:\n\n1. Age: Participants must be between the ages of 7;0 and 11;11.\n2. \u002Fs\u002F Errors: Participants must experience difficulty on \u002Fs\u002F.\n3. English Language Status: Participants must speak English as a dominant language and must have begun learning English before age 3\n4. Hearing Status: Participants must have no reported hearing loss.\n5. Neurodevelopmental Status: Participants must have no reported neurodevelopmental diagnosis. A reported diagnosis of ADHD\u002FADD is admissible if participants meet all other inclusionary criteria.\n6. Technology Access: Participants must have access to a Windows or Apple computer with the ability to join a Zoom session. Additionally, participants must have wired broadband internet connection at home.\n7. Location: Participants must reside in the United States or Canada.\n8. Orthodontic Appliances: Participants must have no orthodontic retainers or appliances that would prevent them from touching the roof of their mouth with their tongue.\n9. Prescreener Recordings: Participants must accurately produce at least 3 items on the \u002Fs\u002F prescreener probe list. Additionally, participants must accurately produce no more than 36 items on the \u002Fs\u002F prescreener probe list.\n10. Dynamic Assessment Probes: Participants must accurately produce at least 5 out of 45 \u002Fs\u002F syllables correctly and must accurately produce no more than 60% of 75 \u002Fs\u002F words correctly. Additionally, participants must produce at least 75% of \u002Fs\u002F errors as dental or lateral distortion errors.\n11. Oral Mechanism Examination: Participants must demonstrate adequate range of motion of the tongue during a brief oral mechanism examination.\n12. Goldman Fristoe Test of Articulation - 3rd Edition (GFTA-3): Participants must score below the 7th percentile on the GFTA-3 and must not demonstrate errors on more than two sounds other than \u002Fs\u002F and \u002Fz\u002F on the GFTA-3.\n13. Test of Integrated Language and Literacy Skills (TILLS): Must receive a scaled score of at least 5 on the Listening Comprehension and Story Retelling subtests of the Test of Integrated Language and Literacy Skills (TILLS).\n14. Linguisystems Articulation Test (LAT) Inconsistency Screener: Participants must produce less than three inconsistencies on the LAT Inconsistency Screener.\n15. Syllable Repetition Task (SRT): Participants must produce less than four additions on the SRT.\n16. Recording: Consent\u002Fassent to recording of assessment and treatment sessions.\n17. General consent\u002Fassent: Consent\u002Fassent provided for study procedures.\n\nExclusion Criteria:\n\n* 1\\. Age: Participants less than 7;0 or greater than 11;11. 2. \u002Fs\u002F Errors: Participants who do not experience difficulty on \u002Fs\u002F. 3. English Language Status: Participants who do not speak English as a dominant language and\u002For who began learning English prior to age 3 4. Hearing Status: Participants who have reported hearing loss, per parent report.\n\n  5\\. Neurodevelopmental Status: Participants who have a reported neurodevelopmental diagnosis. A reported diagnosis of ADHD\u002FADD is admissible if participants meet all other inclusionary criteria.\n\n  6\\. Technology Access: Participants who do not have access to a Windows or Apple computer with the ability to join a Zoom session. Additionally, participants who do not have wired broadband internet connection at home.\n\n  7\\. Location: Participants who do not reside in the United States or Canada. 8. Orthodontic Appliances: Participants who have orthodontic retainers or appliances that would prevent them from touching the roof of their mouth with their tongue.\n\n  9\\. Prescreener Recordings: Participants who accurately produce less than 3 items on the \u002Fs\u002F prescreener probe list. Additionally, participants who accurately produce more than 36 items on the \u002Fs\u002F prescreener probe list.\n\n  10\\. Dynamic Assessment Probes: Participants who accurately produce less than 5 out of 45 \u002Fs\u002F syllables correctly and\u002For who accurately produce more than 60% of 75 \u002Fs\u002F words correctly. Additionally, participants who produce less than 75% of \u002Fs\u002F errors as dental or lateral distortion errors.\n\n  11\\. Oral Mechanism Examination: Participants who do not demonstrate adequate range of motion of the tongue during a brief oral mechanism examination.\n\n  12\\. Goldman Fristoe Test of Articulation - 3rd Edition (GFTA-3): Participants who score above the 7th percentile on the GFTA-3 and\u002For who demonstrate errors on more than two sounds other than \u002Fs\u002F and \u002Fz\u002F on the GFTA-3.\n\n  13\\. Test of Integrated Language and Literacy Skills (TILLS): Participants who receive a scaled score below 5 on the Listening Comprehension and Story Retelling subtests.\n\n  14\\. Linguisystems Articulation Test (LAT) Inconsistency Screener: Participants who produce greater than three inconsistencies on the LAT Inconsistency Screener.\n\n  15\\. Syllable Repetition Task (SRT): Participants who produce greater than four additions on the SRT.\n\n  16\\. Recording: No consent\u002Fassent provided to recording of assessment and treatment sessions.\n\n  17\\. General consent\u002Fassent: No consent\u002Fassent provided for study procedures.","7 Years",{"count":255,"type":22},24,[67],"We want to learn about a new way to help people make the \u002Fs\u002F sound, like in the word \"snake.\" We will be studying a way to teach the \u002Fs\u002F sound that uses very short speech sessions. This study will also collect recordings from people as they say words with the \u002Fs\u002F sound. We will listen to these recordings and check if the words are said clearly.\n\nIn the first visit, we'll do a speech lesson on how to make a clear\n\n\u002Fs\u002F sound. We will also have the participant say some words while we record them talking. If they are a good fit for the study, we will invite them to do a second visit. In the second visit, they will name some pictures, answer some questions, repeat words and sentences, and do some mouth movements. After the second visit, if they are a good fit for the study, we will invite them to do the speech lessons. The speech lessons will each take 10 minutes, and they will have lessons 4 times a week for 8 weeks. They will do these lessons on video chat. They will be randomized to either start right away or after 8 weeks. We'll also ask them to participate in 3 other visits to track progress by having them repeat words with \u002Fs\u002F.",[34],[260],"articulation disorder","2025-10-07",{"date":263,"type":45},"2025-10-09",{"date":265,"type":45},"2025-06-09",{"date":267,"type":22},"2027-01",{"name":199,"class":52},{"id":270,"slug":271,"hasResults":11,"nctId":272,"briefTitle":273,"officialTitle":274,"acronym":4,"eligibilityCriteria":275,"healthyVolunteers":11,"sex":17,"minAge":276,"maxAge":228,"enrollmentInfo":277,"targetDuration":4,"studyType":65,"phases":279,"briefSummary":280,"conditions":281,"keywords":282,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":286,"lastUpdatePostDateStruct":287,"startDateStruct":289,"completionDateStruct":291,"leadSponsor":293,"locationsCount":53},"100548078","phase-1-treatment-targets-in-spanish-and-english-bilingual-speech-intervention-100548078","NCT06416306","Treatment Targets in Spanish and English Bilingual Speech Intervention","Speech Intervention for Bilingual Children","Inclusion Criteria:\n\n* Participants will be regularly exposed to English for at least 3 months in one of the following ways: a) an English-speaking caregiver or sibling who interacts with the child on a daily basis in English, b) attendance at an English-speaking daycare, preschool, or elementary school.\n* Caregivers will have reported concern with their child's speech development and\u002For reduced intelligibility on the Intelligibility in Context Scale in Spanish or English.\n* Participants will present with 5 or more consonants or clusters missing from their phonetic inventories in each language to confirm presence of a speech sound disorder and sufficient gaps in phonological knowledge to warrant treatment.\n\nExclusion Criteria:\n\n* Participants receiving speech or language treatment elsewhere during their participation in this project.","3 Years",{"count":278,"type":22},16,[188],"The goal of this clinical trial is to learn which speech treatment targets result in the greatest amount of speech learning in Spanish-English bilingual children with speech sound disorders. The main questions it aims to answer are:\n\n* Does linguistic complexity of the treatment target increase the amount of generalized learning within the treated language?\n* Does linguistic complexity of the treatment target increase the amount of generalized speech across languages?\n\nResearchers will compare intervention effects across treatment provided in English and Spanish to see if the effect differs according to the language of intervention.\n\nParticipants will:\n\n* Attend between 12 and 18 45-minute speech intervention sessions in Spanish or English for up to 6 weeks\n* Attend assessment visits before and after intervention\n* Attend follow-up assessment visits 1 month and 2 months after intervention",[34],[106,283,284,285],"speech sound disorder","bilingual","treatment targets","2025-08-29",{"date":288,"type":45},"2025-09-05",{"date":290,"type":45},"2024-05-08",{"date":292,"type":22},"2027-03-31",{"name":294,"class":52},"Philip Combiths",{"id":296,"slug":297,"hasResults":11,"nctId":298,"briefTitle":299,"officialTitle":300,"acronym":301,"eligibilityCriteria":302,"healthyVolunteers":11,"sex":17,"minAge":228,"maxAge":98,"enrollmentInfo":303,"targetDuration":4,"studyType":65,"phases":305,"briefSummary":306,"conditions":307,"keywords":308,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":312,"lastUpdatePostDateStruct":313,"startDateStruct":315,"completionDateStruct":316,"leadSponsor":318,"locationsCount":53},"100596151","biofeedback-online-for-sibilant-treatment-100596151","NCT07041723","BiOfeedback, Online for Sibilant Treatment","Online Assessment and Enhancement of Auditory Perception for Speech Sound Errors: BiOfeedback, Online for Sibilant Treatment","BOOST","Inclusion Criteria:\n\n* Age between 8;0 and 17;11 years at the time of enrollment\n* English as the dominant language (must have begun learning English by age 3, per parent report)\n* Passes pure-tone hearing screening at 30 dB hearing level\n* Passes brief examination of oral structure and function\n* Less than 30% accuracy, based on consensus across 2 trained listeners, on a probe list eliciting fricative \u002Fs, z\u002F in various phonetic contexts at the word level\n* No more than 3 sounds other than \u002Fs\u002F in error on the Goldman-Fristoe Test of Articulation-3 (GFTA-3)\n* Diagnosis of ADHD, learning disability, dyslexia, or neurodiversity is admissible if participant meets cutoff scores on evaluation day 1\n* History of CAS is admissible if participant meets cutoff scores on evaluation day 1\n* Braces and removable retainers are admissible\n* Access to a laptop or desktop computer and a quiet space for study sessions\n\nExclusion Criteria:\n\n* Scaled score of 7 or higher on the Recalling Sentences and Formulated Sentences subtests of the Clinical Evaluation of Language Fundamentals-5 (CELF-5)\n* History of permanent hearing loss (temporary hearing loss due to otitis media, including recurrent OM\u002Ftubes, is admissible)\n* History of developmental disorder (e.g., Down syndrome, cerebral palsy)\n* History of major brain injury, surgery, or stroke in the past year (mild concussion is admissible)\n* Active diagnosis of epilepsy or other neurological disorder (permissible if well-controlled for at least 6 months)\n* Current diagnosis of voice or fluency disorder\n* Current presence of orthodontia that crosses the palate (braces and removable retainers are admissible)\n* Lack of access to a laptop or desktop computer and a quiet space for study sessions",{"count":304,"type":22},6,[67],"The goal of this clinical trial is to evaluate the efficacy of sibilant biofeedback treatment delivered via telepractice in six children ages 8:0-17;11 who present with distortions of \u002Fs\u002F. The main questions it aims to answer are:\n\n* Primary hypothesis: Biofeedback treatment for sibilants delivered via telepractice will produce positive gains compared to a no-treatment baseline phase.\n* Secondary hypothesis: Participants will experience positive changes in social-emotional well-being after receiving biofeedback treatment for sibilants as reported by the participants and their guardians.\n\nFollowing the initial evaluation, participants will be randomly assigned to transition from baseline to treatment at one of seven possible points, ranging from 4-10 baseline sessions in which \u002Fs\u002F production will be probed but not treated. All participants will then receive 20, 1-hour biofeedback treatment sessions over 10 weeks with a certified Speech-Language Pathologist via teletherapy, followed by three maintenance sessions.",[34],[309,310,260,311],"speech intervention","biofeedback","lisp","2025-07-30",{"date":314,"type":45},"2025-08-03",{"date":312,"type":45},{"date":317,"type":22},"2027-07",{"name":319,"class":52},"Montclair State University",{"id":321,"slug":322,"hasResults":11,"nctId":323,"briefTitle":324,"officialTitle":325,"acronym":326,"eligibilityCriteria":327,"healthyVolunteers":11,"sex":17,"minAge":125,"maxAge":98,"enrollmentInfo":328,"targetDuration":4,"studyType":65,"phases":330,"briefSummary":331,"conditions":332,"keywords":333,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":337,"lastUpdatePostDateStruct":338,"startDateStruct":340,"completionDateStruct":342,"leadSponsor":344,"locationsCount":53},"100597687","evaluating-the-effectiveness-of-hybrid-and-traditional-speech-therapy-for--and-s-sound-production-100597687","NCT07061730","Evaluating the Effectiveness of Hybrid and Traditional Speech Therapy for \u002Fɹ\u002F and \u002Fs\u002F Sound Production","Genesis: Clinical Trial of Better Speech's Artificial Intelligence Helper for Speech Therapy","GENESIS","Inclusion Criteria:\n\n\\- Response to be filled out by the Parent after sign up.\n\n* Does the child speak American English as one of their primary languages: Yes\n* At what age did the child first begin to learn English? Age 4 or younger\n* Child's current age: \\> 5 years or \\\u003C 17 years 8 months\n* Does the child have any known history of any of the following: autism spectrum disorder, Down Syndrome, cerebral palsy, intellectual disability, permanent hearing loss, epilepsy\u002Fantiepileptic medication, or brain injury\u002Fneurosurgery\u002Fstroke: NO\n* Does the child have a diagnosis of ADD\u002FADHD, Tourette's Syndrome, or OCD? NO\n* Does the child currently have orthodontic appliances that block the roof of the mouth (e.g., palate expanders)? NO\n* Does the child currently have a cleft palate, fluency disorder (e.g., stuttering), or voice disorder? NO\n* Is one of your goals for your child to work on saying the \"r\" or \"s\" sounds? YES\n\nExclusion Criteria:\n\n* EXCLUSIONARY Response to be filled out by the Parent after sign up.\n* Does the child speak American English as one of their primary languages: No\n* At what age did the child first begin to learn English? Age 4 or older\n* Child's current age: \\\u003C5 years or \\> 17 years 8 months\n* Does the child have any known history of any of the following: autism spectrum disorder, Down Syndrome, cerebral palsy, intellectual disability, permanent hearing loss, epilepsy\u002Fantiepileptic medication, or brain injury\u002Fneurosurgery\u002Fstroke: YES\n* Does the child have a diagnosis of ADD\u002FADHD, Tourette's Syndrome, or OCD? YES\n* Does the child currently have orthodontic appliances that block the roof of the mouth (e.g., palate expanders)? YES\n* Does the child currently have a cleft palate, fluency disorder (e.g., stuttering), or voice disorder? YES\n* Is one of your goals for your child to work on saying the \"r\" or \"s\" sounds? NO",{"count":329,"type":22},120,[67],"The purpose of this research study is to evaluate the effectiveness of a hybrid Artificial Intelligence-assisted speech therapy model, which combines the use of an AI speech therapist (Jessica) with traditional speech therapy sessions led by a Speech-Language Pathologist (SLP). This study aims to determine whether the hybrid model improves articulation in children more effectively than traditional SLP-only therapy. Over the course of 8 weeks, participants will receive weekly therapy sessions, and those in the hybrid therapy group will also practice with Jessica between sessions. The study will also gather feedback from parents and speech therapists to assess their experiences and satisfaction with treatment.",[34],[334,335,336,135],"Artificial Intelligence","Articulation","Speech Language Pathology","2025-07-08",{"date":339,"type":45},"2025-07-11",{"date":341,"type":45},"2025-05-01",{"date":343,"type":22},"2026-02",{"name":199,"class":52},{"id":346,"slug":347,"hasResults":11,"nctId":348,"briefTitle":349,"officialTitle":350,"acronym":351,"eligibilityCriteria":352,"healthyVolunteers":11,"sex":353,"minAge":97,"maxAge":98,"enrollmentInfo":354,"targetDuration":4,"studyType":65,"phases":355,"briefSummary":356,"conditions":357,"keywords":358,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":360,"lastUpdatePostDateStruct":361,"startDateStruct":363,"completionDateStruct":365,"leadSponsor":367,"locationsCount":368},"100555833","phase-2-visual-acoustic-intervention-with-service-delivery-in-person-and-via-telepractice-trial-100555833","NCT06517225","Visual-acoustic Intervention With Service Delivery In-person and Via Telepractice Trial","Visual-acoustic Intervention With Service Delivery In-person and Via Telepractice (VISIT) Non-Inferiority Trial","VISIT","Inclusion Criteria:\n\n* Must be between 9;0 and 17;11 (years;months) old at the time of enrollment.\n* Must speak English as the dominant or equally dominant language\n* Must have begun learning English by age 3, per parent report.\n* Must hear a rhotic dialect of English from at least one speaker in the home if the home language is English.\n* Must pass a pure-tone hearing screening.\n* Must pass a brief examination of oral structure and function.\n* Must exhibit less than thirty percent accuracy, based on trained listener ratings, on a probe list eliciting \u002Fr\u002F in various phonetic contexts at the word level.\n* Must demonstrate age-appropriate receptive and expressive language abilities on the Clinical Evaluation of Language Fundamentals-5 (CELF-5).\n* Must have access to a laptop or desktop computer for study sessions in the event of randomization to the telepractice condition.\n* Must have home wifi sufficient to support video calls in the event of randomization to the telepractice condition.\n\nExclusion Criteria:\n\n* Must not exhibit voice or fluency disorder of a severity judged likely to interfere with the ability to participate in study activities.\n* Must not currently have orthodontia that crosses the palate and cannot be removed.\n* Must not have history of permanent hearing loss.\n* Must not have an existing diagnosis of developmental disability such as cerebral palsy or Down Syndrome.\n* Must not have history of major brain injury, surgery, or stroke in the past year.\n* Must not have epilepsy with active seizure incidents with in the past 6 months.\n* Must not show clinically significant signs of apraxia of speech or dysarthria.","FEMALE",{"count":100,"type":22},[102],"Children with speech sound disorder show diminished intelligibility in spoken communication and may thus be perceived as less capable than peers, with negative consequences for both socioemotional and socioeconomic outcomes. New technologies have the potential to transform interventions for speech sound disorder, but there is a lack of rigorous evidence to substantiate this promise. This research will meet a public health need by systematically evaluating the efficacy of visual-acoustic biofeedback intervention delivered in-person versus via telepractice.\n\nThe objective of this study is to test the hypothesis that treatment incorporating visual-acoustic biofeedback can be delivered via telepractice without a significant loss of efficacy. Participants will be randomly assigned to receive identical treatment either via online telepractice or in the laboratory setting. The same software for visual-acoustic biofeedback, staRt, will be used in both conditions. Participants' progress in treatment will be evaluated based on blinded listeners' perceptual ratings of probes produced before and after treatment. Pre and post treatment evaluations will be carried out in person for all participants.",[34],[106,107,359],"motor development","2025-06-23",{"date":362,"type":45},"2025-06-25",{"date":364,"type":45},"2024-07-01",{"date":366,"type":22},"2028-12-31",{"name":116,"class":52},3,{"id":370,"slug":371,"hasResults":11,"nctId":372,"briefTitle":373,"officialTitle":374,"acronym":375,"eligibilityCriteria":376,"healthyVolunteers":11,"sex":17,"minAge":228,"maxAge":98,"enrollmentInfo":377,"targetDuration":4,"studyType":65,"phases":378,"briefSummary":379,"conditions":380,"keywords":381,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":383,"lastUpdatePostDateStruct":384,"startDateStruct":386,"completionDateStruct":388,"leadSponsor":390,"locationsCount":53},"100590600","online-rotating-delivery-of-perceptionproduction-enhanced-treatment-for-rhotics-100590600","NCT06969521","Online Rotating Delivery of Perception\u002FProduction Enhanced Treatment for Rhotics","Online Assessment and Enhancement of Auditory Perception for Speech Sound Errors: Online Rotating Delivery of Perception\u002FProduction Enhanced Treatment for Rhotics","ORDER","Inclusion Criteria:\n\nMust be between 8;0 and 17;11 years of age at the time of enrollment. Must speak English as the dominant language (i.e., must have begun learning English by age 2, per parent report).\n\nMust speak a rhotic dialect of English. Must pass a pure-tone hearing screening at 20dB hearing level. Must pass a brief examination of oral structure and function. Must exhibit less than 30% accuracy, based on consensus across 2 trained listeners, on a probe list eliciting rhotics in various phonetic contexts at the word level.\n\nMust exhibit no more than 3 sounds other than \u002Fr\u002F in error on the Goldman-Fristoe Test of Articulation-3 (GFTA-3).\n\nExclusion Criteria:\n\nMust not receive a T score more than 1.3 SD below the mean on the Wechsler Abbreviated Scale of Intelligence-2 (WASI-2) Matrix Reasoning Must not receive a scaled score of 7 or higher on the Recalling Sentences and Formulated Sentences subtests of the Clinical Evaluation of Language Fundamentals-5 (CELF-5).\n\nMust not have an existing diagnosis of developmental disability or major neurobehavioral syndrome such as cerebral palsy, Down Syndrome, or Autism Spectrum Disorder",{"count":128,"type":22},[67],"The goal of this clinical trial is to determine whether perceptual training enhances speech perception and production outcomes in children with Residual Speech Sound Disorders (RSSD). The main questions it aims to answer are:\n\nDoes pre-treatment speech production accuracy predict treatment response?\n\nDoes perceptual acuity influence the effectiveness of perception-first versus production-first interventions?\n\nResearchers will compare TAU+Perception-first and TAU-first treatment conditions to see if the order of intervention affects speech improvement outcomes, particularly based on participants' initial perception and production accuracy.\n\nParticipants will:\n\nComplete pre-treatment evaluations to assess \u002Fr\u002F production and speech perception.\n\nBe grouped into high or low production and perception accuracy categories based on established thresholds.\n\nBe randomly assigned (using a blocked randomization procedure) to one of two treatment arms via telepractice.\n\nParticipate in the assigned treatment condition designed to target speech sound accuracy.\n\nRandomization is stratified to ensure treatment groups are balanced based on pre-treatment severity in both the perception and production domains.",[34],[283,382,107],"auditory perception","2025-05-22",{"date":385,"type":45},"2025-05-29",{"date":387,"type":45},"2025-05-10",{"date":389,"type":22},"2027-07-01",{"name":319,"class":52},{"id":392,"slug":393,"hasResults":11,"nctId":394,"briefTitle":395,"officialTitle":395,"acronym":396,"eligibilityCriteria":397,"healthyVolunteers":11,"sex":17,"minAge":398,"maxAge":399,"enrollmentInfo":400,"targetDuration":4,"studyType":65,"phases":401,"briefSummary":402,"conditions":403,"keywords":409,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":414,"lastUpdatePostDateStruct":415,"startDateStruct":417,"completionDateStruct":419,"leadSponsor":421,"locationsCount":53},"100555444","measuring-aided-language-development-100555444","NCT06512168","Measuring Aided Language Development","MALD","Inclusion Criteria:\n\n* Clinical Identification of Down Syndrome or Cerebral Palsy + Significant Speech Impairment\n* Must Speak English as a Primary Language\n* Must Be Able to Express At Least 25 Words (using any communication mode)\n* Must Be Able to Accurately Select Picture Symbols on iPad Communication App with at Least 50% Accuracy\n* Vision and Hearing within Functional Limits or Corrected to be within Functional Limits for Study Activities\n\nExclusion Criteria:\n\n* Clinical Diagnosis of Autism or Social Communication Disorder\n* Primary Language Spoken is A Language Other than English","42 Months","60 Months",{"count":128,"type":22},[67],"The focus of the current study is to systematically investigate the psychometric properties of a range of aided language measures, which are based on the Graphic Symbol Utterance and Sentence Development Framework (Binger \\& Kent-Walsh).",[404,405,406,34,407,408],"Down Syndrome","Cerebral Palsy","Apraxia of Speech","Speech Disorders in Children","Speech and Language Disorder",[410,411,412,413],"Augmentative and Alternative Communication","Complex Communication Needs","Assistive Technology","AAC","2025-05-13",{"date":416,"type":45},"2025-05-16",{"date":418,"type":45},"2025-04-01",{"date":420,"type":22},"2028-03-31",{"name":422,"class":52},"University of Central Florida"]