[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"spinal-anesthesia-duration\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:spinal-anesthesia-duration":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,41],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100598954","phase-4-comparative-analysis-of-intraoperative-effect-dexmedetomidine-and-fentanyl-as-an-adjuvant-to-heavy-bupivacaine-in-spinal-anaesthesia-in-lower-limb-orthopedic-surgeries-to-evaluate-the-hemodynamic-stability-and-onset-and-duration-of-motor-block-of-using-intrathecal-dexmedetomidine-and-fentanyl-100598954",false,"NCT07078201","Comparative Analysis of Intraoperative Effect Dexmedetomidine and Fentanyl as an Adjuvant to Heavy Bupivacaine in Spinal Anaesthesia in Lower Limb Orthopedic Surgeries to Evaluate the Hemodynamic Stability and Onset and Duration of Motor Block of Using Intrathecal Dexmedetomidine and Fentanyl","Comparative Analysis of Intraoperative Effect Dexmedetomidine and Fentanyl as an Adjuvant to Heavy Bupivacaine in Spinal Anaesthesia in Lower Limb Orthopedic Surgeries.","Inclusion Criteria:\n\n1. The patient aged range from 20 to 60 years\n2. ASA 1 and 2\n3. Patient prepared for elective lower limb orthopaedic surgeries.\n4. Height 150-180 cm.\n5. Weight 50-70 kg. 6- Either sex male or female.\n\nExclusion Criteria:\n\n\\- 1- Patient refusal. 2- Patient had absolute contraindication to spinal anaesthesia. 3-Patients with neurological disorders, pregnancy, local infection at the site of injection.\n\n4- Patients suffering from dysrhythmia or heart block. 5- Patients with ASA 3 or more.","ALL","20 Years","60 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","Spinal anesthesia is the most widely employed procedure for lower limb orthopedic operations, as it is very cost-effective and simple to apply. These advantages could be restricted because presently existing local anesthetic drugs had relatively short length of action. (1) Spinal anesthesia with 0.5% heavy bupivacaine (hyperbaric) is a common technique, still there was burden of its short duration of action. To overcome this issue, there was a continuous search for an ideal adjuvant.(2) Adjuvants were mostly added to local anesthetic drugs to increase their effectiveness, speedy onset, increase the period of the block, and reduce the local anesthetics dosage, thus reduction their adverse effects.(3) Such adjuvants had been beneficial in extension of analgesia along with initiation of movement though their related side effects.(4)",[27],"Spinal Anesthesia Duration","RECRUITING","2025-12-28",{"date":31,"type":32},"2025-12-30","ACTUAL",{"date":34,"type":32},"2025-07-01",{"date":36,"type":21},"2025-12-25",{"name":38,"class":39},"Nashwa Ahmed","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":48,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":4,"briefSummary":52,"conditions":53,"keywords":59,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":40},"100612666","machine-learning-for-predicting-spinal-anesthesia-duration-100612666","NCT07256548","Machine Learning for Predicting Spinal Anesthesia Duration","Comparative Evaluation of Machine Learning Algorithms for Predicting Spinal Anesthesia Termination Time","Inclusion Criteria:\n\n1. Patients scheduled to undergo total knee arthroplasty between November 2025 and March 2026 at the Kocaeli City Hospital Operating Theaters.\n2. Patients who have provided written informed consent to participate in the study.\n3. Patients whose surgery is planned under spinal anesthesia.\n4. Patients for whom complete clinical data can be obtained during the study period.\n5. Adults aged 18 years or older, classified as American Society of Anesthesiologist's (ASA) Physical Status I or II.\n\nExclusion Criteria:\n\n1. Patients who were converted to general anesthesia during surgery or initially operated under general anesthesia.\n2. Patients who required postoperative intensive care unit (ICU) admission following anesthesia.\n3. Patients who developed surgical complications and for whom postoperative mobilization could not be planned.\n4. Patients with cognitive impairment preventing them from completing pain assessment scales in the postoperative period.\n5. Patients with neuropathic pain, multiple sclerosis, or other neuromotor disorders will be excluded from the study.","18 Years",{"count":50,"type":21},140,"OBSERVATIONAL","Spinal anesthesia provides significant advantages over general anesthesia in knee arthroplasty, including reduced blood loss, faster recovery, and fewer complications. However, predicting its duration is critical for patient safety and effective postoperative management. This study evaluates the usability of machine learning (ML) algorithms to predict the termination time of spinal anesthesia and the patient's readiness for mobilization. Using demographic, surgical, and anesthetic variables, ML models were trained to estimate anesthesia duration. Accurate predictions may improve intraoperative planning, optimize postoperative care, and enhance patient outcomes. Integrating ML-based predictive systems into anesthesia practice can contribute to safer, more efficient, and personalized perioperative management.",[54,55,56,27,57,58],"Spinal Anesthesia","Machine Learning","Knee Arthroplasty, Total","Postoperative Care","Postoperative Acute Pain",[60,61,62,63,64],"spinal anesthesia","machine learning","Knee arthroplasty","spinal anesthesia duration","Acute postoperative pain","2025-12-01",{"date":67,"type":32},"2025-12-08",{"date":69,"type":32},"2025-10-31",{"date":71,"type":21},"2026-03-01",{"name":73,"class":74},"Kocaeli City Hospital","OTHER_GOV"]