[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"spinal-anesthesia-in-elderly-patients\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:spinal-anesthesia-in-elderly-patients":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100620924","height-based-and-conventional-spinal-anaesthetic-dosing-in-geriatric-patients-100620924",false,"NCT07363941","HEIGHT-BASED AND CONVENTIONAL SPINAL ANAESTHETIC DOSING IN GERIATRIC PATIENTS","COMPARISON OF HEMODYNAMIC AND ANAESTHETIC OUTCOMES BETWEEN HEIGHT-BASED AND CONVENTIONAL SPINAL ANAESTHETIC DOSING IN GERIATRIC PATIENTS UNDERGOING LOWER LIMB ORTHOPAEDIC SURGERIES","Inclusion Criteria:\n\nIndividuals aged 60 to 80 years. Either gender (male or female). Patients who are ASA physical status I-III. Individuals scheduled to undergo elective lower limb orthopaedic surgeries (e.g., fracture fixation, total knee replacement, open reduction and internal fixation).\n\nPatients planned to receive spinal anaesthesia as the primary anaesthetic technique.\n\nThose who provide informed written consent for participation in the study.\n\nExclusion Criteria:\n\nIndividuals exhibiting a stature inferior to 150 cm. Patients receiving anti-hypertensive drugs or those on beta blockers or beta-agonists.\n\nPatients with a history of neurological disease like CVA or Parkinsonism. Patients presenting with sepsis (≥ 2 positive SIRS criteria with positive aseptically obtained blood or wound culture).\n\nPatients with a history of coagulation disorders like haemophilia or vWD or those with a history of anti-platelet drug intake in the last 2 weeks.\n\nIndividuals possessing a documented history of hypersensitivity reactions to pharmacological agents utilized in the research.\n\nPatients who will be diagnosed with a skin infection at the spinal needle puncture site.\n\nPatients undergoing emergency orthopaedic procedures requiring immediate intervention","ALL","60 Years","80 Years",{"count":20,"type":21},104,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to find out whether height-based dosing of spinal anaesthesia provides better hemodynamic stability and anesthetic outcome than conventional fixed dosing in elderly patients undergoing lower limb orthopaedic surgery.The main questions this study aims to answer are:\n\n1. Does height-based spinal anaesthetic dosing reduce the risk of hypotension and bradycardia during surgery as compared to conventional fixed dosing?\n2. Does it improve anaesthetic outcomes, such as the onset and duration of sensory and motor block?",[27,28,29],"Geriatric Population","Spinal Anesthesia Induced Hypotension","Spinal Anesthesia in Elderly Patients","RECRUITING","2026-01-15",{"date":33,"type":34},"2026-01-23","ACTUAL",{"date":36,"type":34},"2026-01-03",{"date":38,"type":21},"2026-05-04",{"name":40,"class":41},"Shaheed Mohtarma Benazir Bhutto Institue of Trauma","OTHER"]