[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"spine-health\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:spine-health":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,57,80,121],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":35,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":45,"lastUpdatePostDateStruct":46,"startDateStruct":49,"completionDateStruct":51,"leadSponsor":53,"locationsCount":56},"100606549","neck-and-low-back-pain-in-physical-therapy-students-at-the-university-of-the-west-indies-mona-jamaica-100606549",false,"NCT07177001","Neck and Low Back Pain in Physical Therapy Students at The University of the West Indies, Mona, Jamaica","The Prevalence of Neck and Low Back Pain With a Randomised Controlled Trial Comparing Spine-Specific and Non-Spine Specific Exercise Interventions in Physical Therapy Students at The University of the West Indies, Mona, Jamaica: A Two-Phase Study","Inclusion Criteria:\n\n1. All students enrolled in the Physical Therapy program at the University of the West Indies, Mona Campus, Jamaica during the period November 1, 2025 to October 31, 2026.\n2. Individuals who express a willingness to consent to the study.\n3. Individuals who express a willingness to adhere to the standardised exercise program for the stipulated period.\n\nExclusion Criteria:\n\n1. Individuals with a history of having spine surgery.\n2. Individuals who were previously diagnosed with spine pathology and currently receiving rehabilitation therapy.\n3. Individuals who express an unwillingness to participate in the study.",true,"ALL",{"count":19,"type":20},120,"ESTIMATED","INTERVENTIONAL",[23],"NA","The purpose of this study is to determine the prevalence of neck and low back pain among physical therapy students enrolled at The University of the West Indies, Mona. It also aims to assess students' knowledge, attitudes, and practices regarding spine health and to evaluate the effectiveness of an eight-week standardised spine-specific exercise programme in reducing musculoskeletal pain and improving functional status among those reporting symptoms. The study will be conducted in two phases, beginning with a descriptive cross-sectional assessment of prevalence, followed by a prospective randomised controlled trial in which students experiencing neck and\u002For low back pain will be allocated to either a spine-specific exercise intervention group or a non-spine-specific exercise control group for comparative analysis of outcomes.",[26,27,28,29,30,31,32,33,34],"Back Pain","Low Back Pain","Musculoskeletal Pain","Spine Health","Physical Therapy","Physiotherapist Students","Physiotherapy","Rehabilitation","Neck Pain",[36,37,38,39,40,41,42,43],"lower back pain","low back pain","neck pain","musculoskeletal pain","spine health","physical therapy students","physiotherapy students","rehabilitation","NOT_YET_RECRUITING","2026-02-20",{"date":47,"type":48},"2026-02-24","ACTUAL",{"date":50,"type":20},"2026-04-01",{"date":52,"type":20},"2027-03-31",{"name":54,"class":55},"The University of The West Indies","OTHER",1,{"id":58,"slug":59,"hasResults":11,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":4,"eligibilityCriteria":63,"healthyVolunteers":16,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":64,"targetDuration":4,"studyType":21,"phases":66,"briefSummary":67,"conditions":68,"keywords":73,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":45,"lastUpdatePostDateStruct":76,"startDateStruct":77,"completionDateStruct":78,"leadSponsor":79,"locationsCount":56},"100605850","low-back-and-neck-pain-in-nursing-students-at-the-university-of-the-west-indies-100605850","NCT07167888","Low Back and Neck Pain in Nursing Students at The University of The West Indies","The Prevalence of Neck and Low Back Pain With a Randomised Controlled Trial Comparing Spine-Specific and Non-Spine Specific Exercise Interventions in Nursing Students at The University of the West Indies, Mona: A Two-Phase Study","Inclusion Criteria:\n\n1. All students enrolled in the student nursing program at the University of the West Indies, Mona Campus, Jamaica during the period October 4, 2025 to October 3, 2026.\n2. Individuals who express a willingness to consent to the study.\n3. Individuals who express a willingness to adhere to the standardised exercise program for the stipulated period.\n\nExclusion Criteria:\n\n1. Individuals with a history of having spine surgery.\n2. Individuals who were previously diagnosed with spine pathology and currently receiving rehabilitation therapy.\n3. Individuals who express an unwillingness to participate in the study.",{"count":65,"type":20},400,[23],"The purpose of this study is to identify the prevalence of neck and low back pain in nursing students enrolled at the University of the West Indies, Mona; to assess their knowledge, attitude and practice of good spine health and to determine the outcome of a standardised spine exercise program on nursing students experiencing neck and low back pain, using a prospective randomised control design.",[26,27,28,34,29,69,70,71,72],"Musculoskeletal Pain Disorder","Lower Back Pain","Nursing Students","Preclinical Education",[36,37,39,38,43,74,75,40],"university student","nursing students",{"date":47,"type":48},{"date":50,"type":20},{"date":52,"type":20},{"name":54,"class":55},{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":4,"eligibilityCriteria":86,"healthyVolunteers":16,"sex":17,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":4,"studyType":21,"phases":91,"briefSummary":92,"conditions":93,"keywords":97,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":56},"100621170","occupational-exposure-to-whole-body-vibration-among-us-military-veterans-acute-and-chronic-contributions-to-musculoskeletal-disorders-and-spine-area-pain-100621170","NCT07367139","Occupational Exposure to Whole Body Vibration Among U.S. Military Veterans: Acute and Chronic Contributions to Musculoskeletal Disorders and Spine-Area Pain","Occupational Exposure to Whole Body Vibration Among U.S. Military Veterans: Acute and Chronic Contributions to Musculoskeletal Disorders and Spine-Area Pain, and the Role of Water","Inclusion Criteria:\n\n* English speaking; Male\u002FFemale Veterans age 20-45 years; BMI \\\u003C 30; ability to sit upright for 60 mins; ability to drive to Deerfield, IL; ambulatory\n\nExclusion Criteria:\n\n* Previous spinal surgery; conditions\u002Fdiseases associated with altered pain perception including neurological diseases (e.g., multiple sclerosis, trigeminal neuralgia, central sensitization), major psychiatric disorders, diabetes, neoplasm and cardiovascular disorders, chronic widespread pain diagnosis, pregnant women, MRI contraindications.","20 Years","45 Years",{"count":90,"type":20},112,[23],"Significance to VA: There is a lack of prospective longitudinal studies investigating the relationship between risk factors to Veterans and development and progression of musculoskeletal (MSK) spine injury and pain. Military operational exposure to whole body vibration (WBV) is known to contribute to MSK disorders and pain. Our preliminary studies identified accelerated lumbar and cervical spine degenerative changes in military fighter pilots and helicopter aircrew compared to age- and sex-matched civilian controls. Those changes were likely associated with WBV that military aircrew experience during flight training, primarily affected intervertebral discs (IVDs) and endplates, were associated with neck and back pain symptoms and reduced functional capacity, and are likely to lead to lifelong spine-related issues. Therefore, these aircrew, and other military personnel that experience occupational WBV, are likely to enter the VA Healthcare system with pre-existing degenerative changes and spine-related pain symptoms that can progress over time. Similarly, many Veterans enter civilian occupations that involve WBV such as truck drivers and heavy equipment operators that may also have detrimental effects to the spine and lead to spine-related pain. Development of informed interventions and treatment protocols requires a mechanistic understanding of how the spine is acutely and chronically affected by occupational WBV from both structural and physiological perspectives. Innovation and Impact: Novel multi-parametric application of noninvasive magnetic resonance imaging (MRI) techniques such as arterial spin labeling (ASL), T2\\* decay from ultra short TE, and diffusion MRI can provide early objective indications of endplate degenerative state and IVD hydration and perfusion, and novel application of upright MR imaging allows for gravitational loading of the IVD while observing segmental and region IVD fluid distribution and transport patterns. Specific Aims: The goal of the proposed effort is to characterize the effects of previous military and current civilian occupational WBV on IVD and endplate health and degeneration (Aim 1), and segmental and regional IVD fluid distribution and transport differences (Aim 2). The endplates contain vasculature that permits IVD fluid exchange and may be linked to IVD fluid dynamics. We propose looking for connections between segmental and regional IVD fluid dynamics, degenerative state of the associated endplates, and WBV exposure (acute-controlled and longitudinal-occupational). Finally, we propose evaluating the impact of body hydration state on IVD fluid distribution and transport following acute (30 min) controlled WBV (Aim 3). Cumulatively, these results inform population-specific preventative measures to preserve endplate health for Veterans in occupations that present with WBV and identify potential areas for further research and targeted treatment of MSK disorders and MSK pain. Methodology: This study will explore acute and chronic changes to the structure and physiology of the spine by enrolling Veterans with prior military or current civilian occupation that involves daily WBV. Advanced MRI sequences will identify endplate sclerosis and physiological changes including disc hydration and perfusion. Acute effects of WBV will be assessed using pre\u002Fpost MRI scans with experimental WBV. Path to translation\u002FImplementation: Our existing relationships with VA clinicians, including spine surgeons, physical medicine and rehabilitation, and pain medicine, will ensure VA patient applicability of these findings and will help to translate any outcomes from this research and future studies directly into patient care.",[29,94,95,96],"Spine Injuries and Disorders","Spine Degeneration","Whole Body Vibration",[98,99,96,100,101,102,103,104,105,106,107,108,109,110],"Biomechanics","Magnetic Resonance Imaging (MRI)","Lumbar Spine","Degeneration","Intervertebral Disc","Hydration","Oswestry Disability Index","PainDETECT","Pain Catastrophizing","PROMIS","Brief Pain Inventory","Longitudinal","Endplate","2026-01-16",{"date":113,"type":48},"2026-01-26",{"date":115,"type":20},"2026-07-01",{"date":117,"type":20},"2030-06-30",{"name":119,"class":120},"Milwaukee VA Medical Center","FED",{"id":122,"slug":123,"hasResults":11,"nctId":124,"briefTitle":125,"officialTitle":126,"acronym":4,"eligibilityCriteria":127,"healthyVolunteers":16,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":128,"targetDuration":4,"studyType":21,"phases":130,"briefSummary":131,"conditions":132,"keywords":134,"overallStatus":138,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":142,"completionDateStruct":144,"leadSponsor":146,"locationsCount":147},"100340036","neck-and-low-back-pain-in-medical-students-at-the-university-of-the-west-indies-mona-jamaica-100340036","NCT03707288","Neck and Low Back Pain in Medical Students at The University of the West Indies, Mona, Jamaica","The Prevalence of Neck and Low Back Pain in Medical Students at The University of the West Indies, Mona, Jamaica","Inclusion Criteria:\n\n1. All students enrolled in the medical program at the University of the West Indies, Mona Campus, Jamaica during the period October 1, 2018 to January 2, 2026.\n2. Individuals who express a willingness to consent to the study.\n3. Individuals who express a willingness to adhere to the standardised exercise program for the stipulated period.\n\nExclusion Criteria:\n\n1. Individuals with a history of having spine surgery.\n2. Individuals who were previously diagnosed with spine pathology and currently receiving rehabilitation therapy.\n3. Individuals who express an unwillingness to participate in the study.",{"count":129,"type":20},1000,[23],"The purpose of this study is to identify the prevalence of neck and low back pain in medical students enrolled at the University of the West Indies, Mona; to assess their knowledge, attitude and practice of good spine health and to determine the outcome of a standardised spine exercise program on medical students experiencing neck and low back pain, using a prospective randomised control design.",[26,27,34,133,70,29,28,69],"Neck Pain Musculoskeletal",[36,37,38,135,40,136,137,39],"neck and back pain","medical students","university students","RECRUITING","2025-09-03",{"date":141,"type":48},"2025-09-10",{"date":143,"type":48},"2018-10-01",{"date":145,"type":20},"2026-12-02",{"name":54,"class":55},2]