[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"spine\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:spine":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,46,77,103,137,161,193,226,261,290],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100641629","bispectral-index-in-patients-undergoing-vertebral-surgery-using-artificial-intelligence-programs-a-methodological-study-100641629",false,"NCT07650604","Bispectral Index in Patients Undergoing Vertebral Surgery Using Artificial Intelligence Programs: A Methodological Study","INTERPRETATION AND EVULATION OF THE PROXIMITY TO CLINICAL EXPERIENCE OF BISPECTRAL INDEX (BIS) IN PATIENTS UNDERGOİNG VERTEBRAL SURGERY USING ARTIFICIAL INTELLIGENCE PROGRAMS: A METHODOLOGICAL STUDY","BIS","Inclusion Criteria:\n\n* elective vertebra surgery\n* aged 18-65\n* ASA score I-III\n* BMI \\\u003C30 kg\u002Fm2\n\nExclusion Criteria:\n\n* patient's refusal\n* BMI \\>30 kg\u002Fm2\n* serious liver or kidney disease\n* ASA 4 ve more\n* anatomical abnormality at probe site\n* history of mental or neurological disease,\n* history of previous intracranial aneurysm or intracranial tumor surgery\n* history of moderate or severe pulmonary disease,\n* emergency surgery","ALL","18 Years","65 Years",{"count":21,"type":22},63,"ESTIMATED","OBSERVATIONAL","This study aims to interpret the Bispectral Index (BIS) monitoring method, which we routinely use for monitoring in scoliosis surgery, with artificial intelligence (AI) tools and to determine the accuracy and reliability of AI tools in clinical practice by comparing this interpretation with the interpretations of two clinicians experienced in BIS.",[26,27,28],"Artifical Intelligence","Bispectral Index","Spine",[30,31,32],"artificial intelligence","bispectral index","vertebra surgery","NOT_YET_RECRUITING","2026-06-22",{"date":36,"type":37},"2026-06-24","ACTUAL",{"date":39,"type":22},"2026-06-10",{"date":41,"type":22},"2026-12-10",{"name":43,"class":44},"Antalya Health Sciences University","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":62,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":45},"100631902","early-mobilization-following-elective-spine-surgery-trial-of-in-bed-cycling-100631902","NCT07506720","Early Mobilization Following Elective Spine Surgery: Trial of In-bed Cycling","Early Mobilization Following Elective Spine Surgery: Prospective Randomized Trial of In-bed Cycling on Postoperative Day 1","Inclusion Criteria\n\nMale or female ≥ 18 years old.\n\nPostoperative #0 following elective spinal surgery: decompression with or without fusion, or fusion.\n\nPatient able to walk independently before surgery (does not require assistance from another person and does not use a wheelchair).\n\nPatient admitted directly from the operating room to the ward.\n\nHemodynamically stable:\n\nSystolic blood pressure (SBP): ≥ 90 mmHg and \\\u003C 140 mmHg\n\nOxygen saturation \\> 94%\n\nHeart rate: 50-100 bpm\n\nPatient approved for surgery after preoperative internal medicine evaluation.\n\nPatient alert and conscious.\n\nValid informed consent obtained.\n\nExclusion Criteria\n\nNon-ambulatory preoperatively.\n\nBody Mass Index (BMI) \\> 40 kg\u002Fm².\n\nAcute neurological spinal trauma.\n\nNon-neurological musculoskeletal impairment of the lower limbs (e.g., severe osteoarthritis, hip fracture, amputation) limiting the ability to pedal in bed.\n\nUncontrolled comorbidities preventing surgery or intervention (cardiovascular, respiratory, diabetes).\n\nExpected hospital stay of less than 2 days after surgery.\n\nSurgery-related complications: acute neurological deficit, dural tear, cerebrospinal fluid (CSF) leak, residual spinal instability.\n\nTransfer to intensive care unit or hemodynamic instability.\n\nPersistent hemodynamic instability: SBP \\\u003C 90 mmHg or \\> 200 mmHg, oxygen saturation \\\u003C 88%, heart rate \\\u003C 50 or \\> 100 bpm, temperature \\> 38°C.\n\nCapillary blood glucose outside target values: \\\u003C 4.0 or \\> 7.0 mmol\u002FL fasting or pre-meal, \\\u003C 5.0 and \\> 10.0 mmol\u002FL 2 hours post-meal.\n\nPatient confused, disoriented, or agitated.\n\nPatient already evaluated by physiotherapy for discharge planning or intensive functional rehabilitation.\n\nPatient in isolation.\n\nPatient already discharged.",{"count":54,"type":22},88,"INTERVENTIONAL",[57],"NA","The goal of this clinical trial is to learn if early mobilization using an in-bed cycling device can reduce the amount of time patients spend in bed after elective spine surgery in adults.\n\nThe main questions it aims to answer are:\n\nDoes in-bed cycling on the day after surgery reduce the amount of time patients spend in bed over the next 24 hours?\n\nDoes in-bed cycling reduce the length of hospital stay and improve participation during physiotherapy assessment?\n\nResearchers will compare patients who receive an in-bed cycling session plus standard postoperative care to patients who receive standard postoperative care alone to see if early in-bed cycling improves mobility and recovery after spine surgery.\n\nParticipants will:\n\nBe randomly assigned to either a standard care group or an in-bed cycling group\n\nWear a fitness tracker to measure activity levels and time spent in bed\n\nReceive standard postoperative care\n\nComplete a 30-minute in-bed cycling session on the day after surgery (intervention group only)\n\nBe monitored for pain and vital signs during the study period\n\nUndergo a physiotherapy assessment to evaluate mobility and participation",[28,60,61],"Post Surgery Patients","Recovery Method",[63,64,65,66,67],"Spine Surgery","Postoperative Recovery","Early Mobilization","In-Bed Cycling","Kinesiophobia","RECRUITING","2026-06-17",{"date":34,"type":37},{"date":72,"type":37},"2025-08-01",{"date":74,"type":22},"2029-01",{"name":76,"class":44},"Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":84,"sex":17,"minAge":18,"maxAge":85,"enrollmentInfo":86,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":88,"conditions":89,"keywords":90,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":4},"100632193","the-use-of-two-different-smartphone-applications-in-measuring-sagittal-spinal-curvature-100632193","NCT07510503","THE USE OF TWO DIFFERENT SMARTPHONE APPLICATIONS IN MEASURING SAGITTAL SPINAL CURVATURE","AN INVESTIGATION OF THE INTRA- AND INTER-RATER RELIABILITY OF TWO DIFFERENT SMARTPHONE APPLICATIONS USED IN THE MEASUREMENT OF SAGITTAL SPINAL CURVATURE","Inclusion Criteria:\n\n* Being over 18 years of age,\n* being able to stand and walk without an assistive device,\n* not having experienced back pain or lower extremity pain in the last 6 months,\n* and being willing to participate in the study.\n\nExclusion Criteria:\n\n* Lack of consent,\n* lower extremity injuries (dislocation, sprain) within one month prior to measurement,\n* lower extremity fractures within the last 6 months,\n* tactile sensitivity that prevents the adoption of a free and habitual posture.",true,"25 Years",{"count":87,"type":22},60,"This study will include healthy volunteers aged 18-25 years. Demographic information will be recorded, and an experienced physiotherapist will mark five reference points on the spine of the participants, starting from the cervical spine and extending to the lumbar spine. Angle measurements will then be taken from these five reference points using a gravity inclinometer, an Android smartphone, and an iOS phone. Measurements will be repeated twice on the same day and twice again 24-48 hours later using three different devices. The accuracy and similarity of the measurements taken with these three devices will then be compared.",[28],[91,92,93],"spine","inclinometer","smartphone","2026-04-03",{"date":96,"type":37},"2026-04-08",{"date":98,"type":22},"2026-03-14",{"date":100,"type":22},"2026-04-30",{"name":102,"class":44},"Ahi Evran University Education and Research Hospital",{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":84,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":110,"targetDuration":4,"studyType":55,"phases":112,"briefSummary":113,"conditions":114,"keywords":121,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":45},"100607914","the-prevalence-of-neck-and-low-back-pain-in-fmstrc-staff-at-the-uwi-mona-100607914","NCT07194746","The Prevalence of Neck and Low Back Pain in FMSTRC Staff At the UWI Mona","The Prevalence of Neck and Low Back Pain With a Randomised Controlled Trial Comparing Spine-Specific and Non-Spine Specific Exercise Interventions in Staff of the Faculty of Medical Sciences Teaching & Research Complex at The University of the West Indies, Mona, Jamaica: A Two-Phase Study","Inclusion Criteria\n\n1. All full time academic\u002Foffice\u002Fsupplementary\u002Fancillary staff employed to the Faculty of Medical Science, Training and Research Complex, UWI, Mona.\n2. Individuals with a willingness to adhere to exercise program given in a handout.\n3. Individuals age 18-65\n4. Individuals with at least 1 year experience in their current position.\n\nExclusion Criteria\n\n1. Individuals with a history of having spine surgery\n2. Individuals previously diagnosed with a spine pathology\n3. Individuals currently receiving physiotherapy for a spine problem",{"count":111,"type":22},200,[57],"The purpose of this study is to determine the prevalence of neck and low back pain among full-time staff at the Faculty of Medical Sciences Teaching and Research Complex (FMSTRC), The University of the West Indies, Mona. It also seeks to assess staff members' knowledge, attitudes, and practices regarding spine health and to evaluate the effectiveness of an eight-week standardised spine-specific exercise programme in reducing musculoskeletal discomfort among those experiencing neck and low back pain. The study will be conducted in two phases using a descriptive cross-sectional design followed by a prospective randomised controlled trial, in which participants reporting pain will be allocated to either a spine-specific exercise intervention group or a non-spine-specific exercise control group for comparative analysis of outcomes.",[115,116,117,118,28,119,120],"Neck Pain","Back Pain","Musculoskeletal Pain","Low Back Pain","Work Related Illnesses","Work Related Musculoskeletal Disorders",[122,123,124,125,126,127],"neck pain","back pain","Musculoskeletal pain","low back pain","spinal health","work related musculoskeletal disorders","2026-02-20",{"date":130,"type":37},"2026-02-24",{"date":132,"type":22},"2026-04-01",{"date":134,"type":22},"2027-03-31",{"name":136,"class":44},"The University of The West Indies",{"id":138,"slug":139,"hasResults":11,"nctId":140,"briefTitle":141,"officialTitle":141,"acronym":142,"eligibilityCriteria":143,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":144,"targetDuration":4,"studyType":55,"phases":146,"briefSummary":147,"conditions":148,"keywords":149,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":153,"lastUpdatePostDateStruct":154,"startDateStruct":155,"completionDateStruct":157,"leadSponsor":159,"locationsCount":45},"100592004","differences-in-mechanistic-measures-oxytocin-and-cortisol-of-therapeutic-alliance-between-a-talk-based-therapy-and-soft-tissue-mobilization-in-individuals-with-chronic-spinal-pain-100592004","NCT06987786","Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain","COTHA","Inclusion Criteria include:\n\n* Individuals with chronic spine pain (3 months or greater) (and);\n* who are 18 years of age and older (and)\n* who experience persistent pain of ≥3 on a 10-point scale for the majority of days during the previous 3-months\n\n(The study operationally defines chronic pain using the International Association of the Study of Pain (IASP) pragmatic criteria of pain lasting for 3 months or more that cannot be attributed to another diagnosis or condition).\n\n\\-\n\nExclusion Criteria include:\n\n* Participants with medical conditions that may influence hormone levels during the study (e.g., Cushing's Syndrome, Addison's Disease, etc.) (or),\n* Use of medications (e.g., steroids, antidepressants, or hormonal treatments) that could influence the results (or)\n* Previously diagnosed conditions or factors known to affect cortisol or oxytocin levels, such as chronic stress disorders, hormonal imbalances, or pregnancy.\n\n(After obtaining consent and prior to treatment), the study will screen for potential massage contraindications or other clinical safety considerations and will exclude if:\n\n* participants have infection, skin lesions, (or)\n* Fractures in the region of the massage",{"count":145,"type":22},25,[57],"The goal of this randomized cross-over mechanistic trial is to compare pre- and post-level cortisol and oxytocin changes in patients with chronic spine pain who receive either a hand's on (massage) or a hand's off (talk-based) approach. The study plans to address two primary aims.\n\nSpecific Aim One: Directly compare pre- and post-session oxytocin and cortisol levels across two sessions of massage and talk-based therapy. Hypothesis 1: It is expected that in both treatments, oxytocin will increase and cortisol will decrease, demonstrating no significant between-group differences in hormone levels.\n\nSpecific Aim Two: The study plans to compare pre- and post-session oxytocin and cortisol change scores a therapeutic alliance (TA) scale change scores and PROMIS patient-reported outcomes associated with pain, depression, and disability. Hypothesis 2a: It is projected that there will be moderate +\u002F- relationships (R\\>.4) between the therapeutic alliance change score and oxytocin and cortisol levels, suggesting that the hormones moderately reflect the construct associated with TA. Hypothesis 2b: It is expected that there will be weak (R\\>.1) +\u002F-relationships between hormone measures and PROMIS pain\u002Fdisability\u002Fdepression measures, which reflects similar findings to preliminary work.\n\nParticipants will participant in a massage based treatment and a talk-based treatment approach. Participants will also complete patient report outcomes and will receive a total of four salivary swabs.",[28,118,115],[150,151,152],"Oxytocin","Cortisol","spinal pain","2026-02-18",{"date":128,"type":37},{"date":156,"type":22},"2026-06-01",{"date":158,"type":22},"2026-11-30",{"name":160,"class":44},"Duke University",{"id":162,"slug":163,"hasResults":11,"nctId":164,"briefTitle":165,"officialTitle":166,"acronym":167,"eligibilityCriteria":168,"healthyVolunteers":11,"sex":17,"minAge":169,"maxAge":4,"enrollmentInfo":170,"targetDuration":4,"studyType":55,"phases":172,"briefSummary":173,"conditions":174,"keywords":179,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":184,"lastUpdatePostDateStruct":185,"startDateStruct":187,"completionDateStruct":189,"leadSponsor":191,"locationsCount":45},"100625370","evaluation-of-the-accuracy-of-the-ecential-robotics-robot-in-spinal-surgery-100625370","NCT07421752","Evaluation of the Accuracy of the eCential Robotics Robot in Spinal Surgery","Evaluation of the Accuracy of the eCential Robotics Robot in Spinal Surgery at Amiens Picardie University Hospital","Robotec Amiens","Inclusion Criteria:\n\n* Patients aged 5 years or older.\n* Treated at CHU Amiens Picardie for spinal surgery requiring implantation of pedicle screws.\n* Informed consent signed by patient or legal representative and child.\n* Membership of a social security scheme.\n* Negative pregnancy test for adolescent women of childbearing age\n\nExclusion Criteria:\n\n* Patient managed by a practitioner with no experience of the eCential Robotics robot.\n* Patient requiring a technique without implantation of pedicle screws.\n* Patients already suffering from deterministic radiation effects\n* Pregnant, parturient or breast-feeding women.\n* Patients under guardianship or curators, under safeguard of justice or deprived under public law.","5 Years",{"count":171,"type":22},45,[57],"Spinal surgery has evolved considerably over the years, and the introduction of advanced technologies has played a crucial role in improving clinical outcomes. The use of surgical robots, such as the eCential Robotic system, has emerged as an innovative solution for optimizing the precision and safety of procedures, particularly the placement of pedicle screws in the spine.\n\nThe eCential Robotics surgical robot offers several advantages for the placement of pedicle screws in the spine. Various studies have demonstrated a significant improvement in screw accuracy and stability, reducing revision surgery rates with surgical robots. The system enables advanced preoperative planning based on three-dimensional imaging, improving understanding of the patient's specific anatomy. This study will also provide a clinical basis for the CE marking process.\n\nThe objective of this prospective study is to collect data confirming safety, performance and clinical benefits of the eCential Robotics robot when used during spine and pelvic surgeries.",[175,176,177,28,178],"Pedicle Screw Accuracy","Robot","Navigation","Scoliosis",[180,181,182,91,183],"Pedicle screw accuracy","robot","navigation","scoliosis","2026-02-17",{"date":186,"type":37},"2026-02-19",{"date":188,"type":37},"2025-11-21",{"date":190,"type":22},"2028-11",{"name":192,"class":44},"Centre Hospitalier Universitaire, Amiens",{"id":194,"slug":195,"hasResults":11,"nctId":196,"briefTitle":197,"officialTitle":198,"acronym":4,"eligibilityCriteria":199,"healthyVolunteers":11,"sex":17,"minAge":200,"maxAge":4,"enrollmentInfo":201,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":203,"conditions":204,"keywords":212,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":216,"lastUpdatePostDateStruct":217,"startDateStruct":219,"completionDateStruct":221,"leadSponsor":223,"locationsCount":225},"100565112","comparison-of-the-diagnosis-time-of-vet-and-scl-in-patients-with-intraoperative-coagulopathy-100565112","NCT06637943","Comparison of the Diagnosis Time of VET and SCL in Patients With Intraoperative Coagulopathy","Comparison of Time Taken for Diagnosing Intraoperative Coagulopathies: Point-of-care Viscoelastic Tests vs Standard Central Laboratory Tests","Inclusion Criteria:\n\n* patients who will undergo elective surgery with a high risk of moderate to severe amount of intraoperative bleeding or coagulopathy (e.g., cardiac surgery, joint replacement, spine surgery, hepatectomy, radical prostatectomy)\n* patients who provide written informed consent\n* patients who may warrant the intraoperative use of POC viscoelastic test or SCL test\n\nExclusion Criteria:\n\n* pregnancy\n* withdrawal of consent\n* termination of surgery without performing either POC viscoelastic test or SCL tests\n* when the study conductor deems it inappropriate to proceed with the protocol with the patient","19 Years",{"count":202,"type":22},210,"The present study is a prospective, multi-center observational trial comparing the times taken to diagnose coagulopathies using point-of-care (POC) viscoelastic tests or standard central laboratory tests (SCL tests) in patients with intraoperative bleeding.",[205,206,28,207,208,209,210,211],"Arthritis of Knee","Arthritis of Hip","Prostate Cancer","Hepatic Cancer","Valvular Disorder","Ischemic Heart Disease","Aortic Diseases",[213,214,215],"viscoelastic test","standard central laboratory test","coagulation","2025-12-01",{"date":218,"type":37},"2025-12-08",{"date":220,"type":22},"2026-02-01",{"date":222,"type":22},"2026-05-31",{"name":224,"class":44},"Konkuk University Medical Center",4,{"id":227,"slug":228,"hasResults":11,"nctId":229,"briefTitle":230,"officialTitle":230,"acronym":4,"eligibilityCriteria":231,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":232,"targetDuration":4,"studyType":55,"phases":234,"briefSummary":236,"conditions":237,"keywords":243,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":252,"lastUpdatePostDateStruct":253,"startDateStruct":255,"completionDateStruct":257,"leadSponsor":259,"locationsCount":45},"100610247","phase-4-evaluation-of-the-efficacy-of-stratafix-for-neurosurgical-cranial-and-spine-procedures-100610247","NCT07225101","Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures","Inclusion Criteria:\n\n* Elective or emergent surgical approaches for cranial or spine neurosurgical approaches, requiring sutures for wound closure, requiring multilayer wound closure\n\nExclusion Criteria:\n\n* Patients with prior surgical wound dehiscence or infection\n* Patients with allergy to suture material",{"count":233,"type":22},160,[235],"PHASE4","This research is studying a device already approved by the Food and Drug Administration (FDA) to treat wound closures. Researchers are studying a large group of people to continue to learn information about the safety of the STRATAFIX suture and how people's bodies react to using it over a long period of time. This research will provide additional information about using STRATAFIX sutures to close surgical wounds.",[238,239,28,240,241,242],"Wound Closure","Brain Tumor Adult","Neurovascular","Hemorrhagic Stroke, Intracerebral","Traumatic Brain Injury",[244,245,246,247,91,248,249,250,251],"Superficial surgical site infection","Suture material","Wound closure techniques","brain tumor","spine trauma","neurosurgery","hemorrhagic stroke","traumatic brain injury","2025-11-03",{"date":254,"type":37},"2025-11-05",{"date":256,"type":37},"2025-11-01",{"date":258,"type":22},"2026-12-31",{"name":260,"class":44},"University of Michigan",{"id":262,"slug":263,"hasResults":11,"nctId":264,"briefTitle":265,"officialTitle":266,"acronym":4,"eligibilityCriteria":267,"healthyVolunteers":11,"sex":17,"minAge":268,"maxAge":19,"enrollmentInfo":269,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":271,"conditions":272,"keywords":275,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":282,"lastUpdatePostDateStruct":283,"startDateStruct":285,"completionDateStruct":287,"leadSponsor":288,"locationsCount":45},"100585863","reliability-of-phas-in-postural-hyperkyphosis-100585863","NCT06907901","Reliability of PHAS in Postural Hyperkyphosis","Reliability Analysis of the Postural Habits and Awareness Scale (PHAS) in Patients With Postural Hyperkyphosis","Inclusion Criteria:\n\n* Age between 8 and 65 years\n* Diagnosed with postural hyperkyphosis (Cobb angle ≥ 50° confirmed by clinical and radiological evaluation)\n* Ability to perform daily activities independently\n* Voluntary participation and signed informed consent\n\nExclusion Criteria:\n\n* Presence of scoliosis or other spinal deformities\n* Kyphosis due to severe osteoporosis or pathological fractures\n* Diagnosis of ankylosing spondylitis or other inflammatory spinal diseases\n* Functional limitations due to acute or chronic pain\n* Previous postural awareness training or spinal rehabilitation within the last 6 months\n* Cognitive impairment or severe psychiatric disorder preventing independent questionnaire completion","8 Years",{"count":270,"type":22},128,"This observational, cross-sectional study aims to evaluate the reliability of the Postural Habits and Awareness Scale (PHAS) in patients with postural hyperkyphosis. The PHAS is designed to assess individuals' postural awareness and habits through four subscales. A total of 128 participants diagnosed with postural hyperkyphosis will complete the PHAS and the Kyphosis-Specific Spinal Appearance Questionnaire (KSSA). Test-retest reliability will be assessed by reapplying the PHAS after two weeks. Internal consistency, test-retest reliability, and concurrent validity will be analyzed. The study aims to provide a valid and reliable tool for evaluating postural awareness in clinical practice and future rehabilitation studies.",[273,28,274],"Postural Kyphosis","Assessment, Self",[276,277,278,279,280,281],"Hyperkyphosis","Postural Habits","Postural Awareness","Psychometric Analysis","Spinal Deformity","Postural Evaluation","2025-09-25",{"date":284,"type":37},"2025-10-01",{"date":286,"type":37},"2025-06-01",{"date":156,"type":22},{"name":289,"class":44},"Istanbul University - Cerrahpasa",{"id":291,"slug":292,"hasResults":11,"nctId":293,"briefTitle":294,"officialTitle":295,"acronym":296,"eligibilityCriteria":297,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":298,"targetDuration":4,"studyType":55,"phases":300,"briefSummary":301,"conditions":302,"keywords":307,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":313,"lastUpdatePostDateStruct":314,"startDateStruct":316,"completionDateStruct":318,"leadSponsor":319,"locationsCount":45},"100591026","phase-4-effect-of-magnesium-on-neuromonitoring-100591026","NCT06975072","Effect of Magnesium on Neuromonitoring","Pharmacokinetics and Impact of Magnesium Sulfate on Neuromonitoring in Spinal Surgery","MgNm","Inclusion Criteria:\n\nAdult patients (\\>18 years of age) undergoing open thoracolumbar fusion with planned neuromonitoring\n\nExclusion Criteria:\n\n1. Patients with a history of significant cardiac disease (LVEF \\\u003C35%, 2nd\u002F3rd-degree block without a pacemaker, or significant arrhythmia)\n2. Patients with kidney disease (GFR \\\u003C30), or hepatic dysfunction (history of cirrhosis)\n3. Allergy or sensitivity to magnesium\n4. Patient with neuromuscular disease such as myasthenia graves",{"count":299,"type":22},20,[235],"Intraoperative neurophysiologic monitoring (IONM) is commonly used during complex spinal surgery to monitor the integrity of neural structures and improve the perioperative safety profile. Transcranial Motor Evoked Potentials (TcMEPs) monitor the integrity of the motor pathways and are one of the most commonly used monitoring modalities in spinal surgery. Because inhaled anesthetics can negatively affect the ability to monitor TcMEPs, anesthesiologists commonly use a combination of propofol and opioids to maintain the anesthetic state. Additionally, anesthesiologists will frequently administer intravenous infusions of medications that can decrease postoperative pain and opioid use (called opioid-sparing adjuncts) because spinal surgeries result in significant postoperative pain. Despite the increasing use of these agents, there is scant clinical data about how they may affect the integrity of TcMEP monitoring. Magnesium (Mg), a N-methyl-d-aspartate receptors (NMDA) receptor antagonist, is one of the adjuncts with robust data supporting clinical efficacy to decrease pain and opioid use on TcMEPs. Mg has been used clinically for decades. The investigators commonly utilize intravenous magnesium as a component of our spinal anesthesia protocol. However, there is only a single case report that discusses the effects of Mg on TcMEPs. Here the investigators propose a prospective clinical trial to quantitatively assess the effects of various Mg plasma levels on TcMEPs. There is a lack of literature on the pharmacokinetics of magnesium in non-pregnant patients.",[28,303,63,304,305,306],"Pain","Spine Surgery With Neuromonitoring","Spine Surgery With Motor Evoked Potential Monitoring","Spine Fusion",[91,308,309,310,311,312],"spine surgery","spine fusion","magnesium","neuromonitoring","motor evoked potential monitoring","2025-07-02",{"date":315,"type":37},"2025-07-08",{"date":317,"type":37},"2025-07-01",{"date":100,"type":22},{"name":320,"class":44},"University of California, San Francisco"]