[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"sport-related-concussion\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:sport-related-concussion":86},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,70],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100631943","pilot-study-on-the-correlation-between-accelerations-experienced-100631943",false,"NCT07507253","Pilot Study on the Correlation Between Accelerations Experienced","Pilot Study on the Correlation Between Accelerations Experienced During Matches by Professional Rugby Players and a Profile of Salivary Biomarkers Identified in the Literature as Related to Concussion.","BIOIMPACT","Inclusion Criteria:\n\n* Male subject\n* Subject aged between 19 and 20 years\n* Subject willing to follow the study procedures\n* Subject capable of understanding the purpose, nature, and methodology of the study\n* Subject affiliated with a French social security scheme or a beneficiary of such a scheme\n* Subject who has signed the non-opposition to participation in the research\n* Subject who has signed the informed consent for salivary micro-RNA analysis\n* Subject selected in the French under-20 rugby team (U20).\n\nExclusion Criteria:\n\n* Subject not affiliated with a French Social Security scheme or not a beneficiary of such a scheme\n* Subject deprived of liberty, protected adults, vulnerable persons, or minors\n* Subject with proven or suspected chronic infectious disease that may pose a risk of contamination during sample handling (laboratories not equipped to handle this type of sample)\n* Subject suffering from Gougerot-Sjögren syndrome (dry syndrome)\n* Refusal to sign the non-opposition\n* Refusal to sign the informed consent for salivary micro-RNA analysis.\n\nSpecific Non-Inclusion Criteria:\n\n* Subject who has suffered a recent stroke or epileptic event (within the last two months)\n* Subject suffering from neurological diseases.",true,"MALE","19 Years","20 Years",{"count":22,"type":23},66,"ESTIMATED","OBSERVATIONAL","Concussion, or mild traumatic brain injury, accounts for 85% of brain injuries and is common in both professional and amateur sports. It results from kinetic impacts causing a temporary disruption of brain function, often without visible abnormalities on imaging, making diagnosis difficult.\n\nThe majority of concussions remain undetected, without specific management. To facilitate detection, the development of reliable salivary BMs is essential, as they offer a non-invasive, rapid, and simple method for early identification of biological changes related to concussions.",[27],"Sport Related Concussion",[29,30,31,32],"Concussion","Biomarkers","Sport","Instrumented mouthguards","RECRUITING","2026-04-03",{"date":36,"type":37},"2026-04-09","ACTUAL",{"date":39,"type":37},"2025-01-22",{"date":41,"type":23},"2028-01-21",{"name":43,"class":44},"Sys2Diag","OTHER_GOV",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":17,"sex":18,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":58,"conditions":59,"keywords":60,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":45},"100527560","salivary-biomarkers-for-concussion-100527560","NCT06149351","Salivary Biomarkers for Concussion","Determination of the Physiological Profile and Evaluation of the Effect of Intense Physical Exertion Among Professional Athletes","SportCo","Inclusion Criteria:\n\n* Male participants aged between 18 and 50 years old.\n* Participants willing to comply with the study procedures.\n* Participants capable of understanding the purpose, nature, and methodology of the study.\n* Participants affiliated to a French social security system or beneficiaries of such a system.\n* Participants who have signed the non-opposition form to participate in the research.\n\nNon-inclusion Criteria:\n\n* Participant not affiliated to a French social security system or not a beneficiary of such a system.\n* Participants deprived of liberty, protected adults, vulnerable individuals, or minors.\n* Participants with a proven or suspected chronic infectious disease that may introduce a risk of contamination during sample handling (laboratories not equipped to handle this type of sample).\n* Refusal to sign the non-opposition form to participate in the research.\n\nNon-inclusion specific criteria\n\n* Subject who has had a recent stroke or epilepsy event (within the past two months).\n* Subject suffering from neurological diseases.","18 Years","50 Years",{"count":57,"type":23},80,"Concussion (CC) (also called mild head trauma), which accounts for 85% of all head injuries, is very common in professional and amateur athletes. CC is an injury to the brain resulting from the direct or indirect impact of external mechanical forces, momentarily disrupting its function on a cellular level. Unlike more serious head injury (moderate and severe), which can be diagnosed using neuroimaging techniques (CT, MRI, etc.), patients suffering from CC do not necessarily show visible signs of structural abnormalities. As a result, diagnosis of CC is offen difficult.\n\nRecently, several salivary biomarkers (proteins and nucleic acids) of sport related concussion have been identified in professional athletes. However, their reference values have not been determined with sufficient robustness to enable their employment in concussion diagnostic tests.",[27],[61],"Concussion, Biomarkers, Sport","2026-03-12",{"date":64,"type":37},"2026-03-16",{"date":66,"type":37},"2023-12-12",{"date":68,"type":23},"2027-12-12",{"name":43,"class":44},{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":4,"eligibilityCriteria":76,"healthyVolunteers":17,"sex":77,"minAge":78,"maxAge":4,"enrollmentInfo":79,"targetDuration":4,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":45},"100575645","effect-of-neck-training-on-outcomes-related-to-sport-related-concussion-100575645","NCT06774976","Effect of Neck Training on Outcomes Related to Sport-Related Concussion","Efficacy and Acceptability of an Evidence-Based Neck Resistance Training Program on Head Acceleration and Isometric Neck Strength in Female Soccer Players: A Pilot Quasi-Experimental Trial","Inclusion Criteria:\n\n* Teams that are located in Skåne county\n* Teams that are trained by professional trainers who are financially compensated for their work\n* Teams that are not engaged in any targeted neck-strengthening exercises during the trial period beyond those prescribed within the trial\n* Players that are 16 years of age or older\n* Players that regularly attend all senior-level team activities, including training and match sessions\n* Players that free of any injuries to their upper or lower limbs, torso, neck, or head at the time of enrolment\n* Players with no history of undiagnosed neck pain within the previous three months.","FEMALE","16 Years",{"count":80,"type":23},50,"INTERVENTIONAL",[83],"NA","Sport-related concussion (SRC) is a significant concern in soccer. This pilot quasi-experimental trial aims to investigate the efficacy and acceptability of an evidence-based neck resistance exercise program in female soccer athletes for SRC prevention. The 8-week intervention includes dynamic and static neck exercises designed to reduce linear and rotational head accelerations, improve neck muscle strength, and minimise SRC risk. The study will evaluate program outcomes through laboratory testing, questionnaires, and user feedback. Findings from this pilot study will inform the design and implementation of a full-scale study, aiming to advance preventive strategies in SRC and address the underrepresentation of female athletes in research.",[86],"Sport-related Concussion",[88,89,90,91],"Sport-related concussion","Neck muscles","Primary prevention","Resistance training","NOT_YET_RECRUITING","2025-03-14",{"date":95,"type":37},"2025-03-17",{"date":97,"type":23},"2025-09",{"date":99,"type":23},"2026-12",{"name":101,"class":102},"Lund University","OTHER"]