[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"sports-related-concussion\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:sports-related-concussion":108},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,53,86],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":35,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100640010","mobile-dual-task-brain-and-balance-intervention-for-concussion-recovery-100640010",false,"NCT07599475","Mobile Dual-Task Brain and Balance Intervention for Concussion Recovery","Boosting Brain and Balance: A Mobile Dual-Task Intervention for Athletes With Concussion and Mild Traumatic Brain Injury (mTBI)","Inclusion Criteria:\n\n* Adults aged 18 to 40 years\n* Self-reported history of sports-related concussion (SRC) or mild traumatic brain injury (mTBI) within the past 3 to 12 months\n* Meets criteria for mTBI based on a standardized screening method (e.g., Ohio State University TBI Identification Method)\n* Able to safely participate in light physical activity (e.g., walking) and simple cognitive tasks based on self-report and observational screening by the research team\n* Able to read and understand English (if applicable for study materials)\n* Able to provide informed consent\n* Has access to and is able to use a smartphone or mobile device to complete daily app-based activities\n\nExclusion Criteria:\n\n* Age younger than 18 years or older than 40 years\n* History of moderate or severe traumatic brain injury\n* Concussion or mTBI occurring less than 3 months or more than 12 months prior to enrollment\n* Self-reported active medical disease or history of neurological or psychiatric conditions unrelated to concussion\n* Self-reported other medical conditions that would limit safe participation in light physical activity (e.g., walking or balance tasks)\n* Currently on prescribed medications that may significantly affect cognitive function, balance, neurological function, or safe participation in light physical activity\n* Inability to use a smartphone or mobile device required for study participation\n* Inability to read or understand English (as study materials and the mobile application are currently available only in English)","ALL","18 Years","40 Years",{"count":20,"type":21},20,"ESTIMATED","INTERVENTIONAL",[24],"NA","This research study examines recovery after a sports-related concussion or mild head injury. Many athletes experience lingering problems with thinking, balance, and mood months after a concussion.\n\nWe are testing a new home-based program called BraW-Day™ (Brain \\& Walk Exercise Every Day). This 14-day program uses a mobile app on your smartphone and combines simple brain exercises (like counting backwards) with walking exercises. The idea is that doing these tasks together may help your brain and body recover more effectively.\n\nWhat You'll Do:\n\n* Two in-person visits at UNLV (baseline and after 14 days) for assessments\n* Daily 15-minute exercises at home using the BraW-Day app\n* Provide a small saliva sample for biomarker testing\n* Complete brief questionnaires about your symptoms and health\n\nPotential Benefits:\n\nYou may experience improvements in thinking, balance, or mood. Even if you don't benefit directly, your participation will help researchers understand how to better support athletes recovering from concussion.\n\nWho Can Join:\n\n* Ages 18-40\n* Had a sports-related concussion or mild head injury within the past 3-12 months\n* Have a smartphone and can safely do light walking and simple tasks\n\nThis study is registered at ClinicalTrials.gov and approved by the UNLV Institutional Review Board to protect your safety and rights.",[27,28,29,30,31,32,33,34],"Mild Traumatic Brain Injury (mTBI)","Sports-related Concussion","Heart Rate Variability (HRV)","Walking","Oculomotor","Saliva","Exosomal microRNA","Cognitive Function",[36,37,38,39],"dual-task","mild traumatic brain injury (mTBI)","sports-related concussion","BraW-Day","NOT_YET_RECRUITING","2026-05-14",{"date":43,"type":44},"2026-05-20","ACTUAL",{"date":46,"type":21},"2026-05-15",{"date":48,"type":21},"2027-04-30",{"name":50,"class":51},"Hyunhwa Lee","OTHER",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":62,"maxAge":4,"enrollmentInfo":63,"targetDuration":4,"studyType":22,"phases":65,"briefSummary":66,"conditions":67,"keywords":72,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":52},"100626106","ecological-test-standardization-for-concussion-assessment-in-football-players-100626106","NCT07431320","Ecological Test Standardization for Concussion Assessment in Football Players","COMOFOOT","Inclusion Criteria:\n\nProfessional football players:\n\n* Male professional football players from French clubs\n* Aged 18 years and older\n* Provided written informed consent to participate\n* Adequate understanding of written and spoken French\n\nYouth football players from training centers:\n\n* Registered in a training center affiliated with a French football club\n* Aged 16 years and older\n* Provided written assent to participate, with parental or legal guardian consent for minors\n* Adequate understanding of written and spoken French\n\nExclusion Criteria:\n\nAll players:\n\n* History of concussion in the past 6 months (for inclusion, a statement from the club physician confirming no concussion in the past 6 months will be requested)\n* Physically unfit (if applicable, a medical certificate from the club physician will be required, e.g., incapacitating musculoskeletal injury)",true,"MALE","16 Years",{"count":64,"type":21},100,[24],"Concussion is a major concern in the sports world. It represents an immediate and transient alteration of neurological functions due to a direct or indirect trauma, with or without loss of consciousness. Concussions affect between 1.6 and 3.8 million people per year in the United States across all sports. The prevalence varies depending on the sport. In France, the incidence of sport-related concussions is estimated at 200,000 cases. According to the French Academy of Medicine (March 2025), concussions account for between 5% and 9% of all sports-related injuries. Among these cases, 30% involve individuals aged 5 to 19. Football (soccer) is one of the most affected sports, with its 2 million registered players. In French professional football (Ligue 1 and 2), during the 2023-2024 season, one concussion was recorded every 55 matches on average (declared concussion). During the 2018-2019 and 2019-2020 seasons, the rate of matches with concussion was approximately 2.5%. In professional rugby, it is estimated that one concussion occurs every three matches in France.\n\nThere are no precise statistics on the number or frequency of concussions in amateur football in France, due to a lack of reporting and insufficient diagnosis. Currently, practical recommendations exist for managing football players from the moment of impact on the field, implemented within the French Football Federation. The current concussion protocol includes a standardized tool for evaluating concussion intended for healthcare professionals, the SCAT6. However, this protocol is not always sufficient, and return-to-play sometimes occurs too early. Indeed, current assessments are too brief and do not evaluate all cognitive functions. They do not allow a clear understanding of the real on-field consequences. It is estimated that 50% of athletes return to play too early after a concussion, with risks of neurological complications or prolonged symptoms.\n\nHowever, defining rest time and return-to-play criteria is not straightforward. In practice, return to play relies, among other things, on neuropsychological tests, whose interpretation is difficult in the absence of baseline data. The concussion protocol does not allow for an accurate determination of whether performance has normalized without this neuropsychological baseline.\n\nRecent European and international recommendations advise conducting pre-season assessments to provide comparative values. Several studies have been published on the type of pre-season assessments to perform, most using paper-and-pencil or computerized neurocognitive tests.\n\nThe current concussion protocol relies mainly on paper-and-pencil tests. However, the literature shows dissociations between cognitive performance measured in ecological environments and performance measured through paper-and-pencil tests. Ecological tasks have the advantage of closely approximating the daily actions of a player and assessing cognitive functioning more precisely.\n\nThus, these ecological tasks, combined with a baseline assessment, would improve the evaluation of athletes following a concussion. These tasks would facilitate return-to-play decisions through more objective observations and normed data. Finally, ecological tasks would enhance player monitoring and allow a more accurate understanding of their health status.\n\nFor this reason, it seems necessary to develop a standardized ecological test performed in real-game situations. This would improve decision-making regarding return to play without medically endangering the player and would allow better understanding of the cognitive effects of concussion. These tasks will first be reviewed and tested by experts (players, football staff members, national concussion reference physician, and neuropsychologists) for feedback and refinement.",[68,28,69,70,71],"Concussion, Brain","Football Players","Traumatic Brain Injury, Mild","Healthy Volunteer Male Subjects",[73,74,75,76],"ecological test","reliability","standardization","cognitive assessments","2026-02-18",{"date":79,"type":44},"2026-02-24",{"date":81,"type":21},"2026-04",{"date":83,"type":21},"2028-04",{"name":85,"class":51},"Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de Kerpape",{"id":87,"slug":88,"hasResults":11,"nctId":89,"briefTitle":90,"officialTitle":90,"acronym":4,"eligibilityCriteria":91,"healthyVolunteers":11,"sex":16,"minAge":92,"maxAge":17,"enrollmentInfo":93,"targetDuration":4,"studyType":22,"phases":95,"briefSummary":96,"conditions":97,"keywords":4,"overallStatus":98,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":52},"100534514","assessing-the-effects-of-photobiomodulation-on-clinical-recovery-from-concussion-in-adolescents-100534514","NCT06239818","Assessing the Effects of Photobiomodulation on Clinical Recovery From Concussion in Adolescents","Inclusion Criteria:\n\n* current participants in a school- or club-sponsored sport (contact or non-contact)\n* access to wireless internet service at home\n* diagnosis of sports-related concussion (SRC) (according to consensus diagnostic criteria) by a licensed healthcare provider,3-7 days from the concussive injury at the time of enrolment\n* considered at-risk for protracted recovery based on Immediate Post-concussion Assessment and Cognitive Testing (ImPACT) performance and symptom reporting on the Post-Concussion Symptom Scale (PCSS)\n\nExclusion Criteria:\n\n* acute neurologic deterioration to a Glasgow Coma Scale score less than 13\n* neurosurgical intervention\n* abnormal CT scan\n* concomitant extracranial injury worse than mild\n* pre-injury conditions which confound effects of SRC (e.g., epilepsy, schizophrenia, bipolar illness, mental deficiency, hospitalization for TBI)\n* substance dependence\n* inability to speak fluent English\n* Individuals who are taking benzodiazepines, anti-convulsants, mood stabilizers, stimulants, opioids, sleep aids, or other neuropsychiatric medications","13 Years",{"count":94,"type":21},30,[24],"The purpose of this study is to compare effects of Photobiomodulation therapy (PBMt) to standard of care in adolescent athletes at risk for delayed recovery from subacute sports concussion, to substantiate the impact of subacute PBMt over time on functional and structural connectivity of the brain using advanced MRI sequences and to correlate the psychological and behavioral outcomes to neuroimaging findings",[28],"RECRUITING","2025-07-16",{"date":101,"type":44},"2025-07-20",{"date":103,"type":44},"2024-04-17",{"date":105,"type":21},"2026-04-01",{"name":107,"class":51},"The University of Texas Health Science Center, Houston","Sports Related Concussion"]