[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"stage-iii-prostate-cancer\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:stage-iii-prostate-cancer":38},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,58],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":45,"whyStopped":4,"lastUpdateSubmitDate":46,"lastUpdatePostDateStruct":47,"startDateStruct":50,"completionDateStruct":52,"leadSponsor":54,"locationsCount":57},"100353326","nutrition-and-exercise-interventions-for-androgen-deprivation-therapy-induced-obese-frailty-in-elderly-and-non-elderly-survivors-of-advanced-prostate-cancer-100353326",false,"NCT03880422","Nutrition and Exercise Interventions for Androgen Deprivation Therapy-Induced Obese Frailty in Elderly and Non-Elderly Survivors of Advanced Prostate Cancer","Inclusion Criteria:\n\n* Biopsy-confirmed prostate adenocarcinoma of any stage\u002Fgrade\n* Prescribed or already receiving continuous ADT for \\\u003C 5 years\n* Hemoglobin \\> 11 g\u002FdL\n* Creatinine \\\u003C 1.5 x upper limit of normal (ULN), AST or ALT \\\u003C2 x ULN within 6 months prior to enrollment\n* Liver function tests \\\u003C 2 x ULN\n* Able to walk unassisted at least 100 meters (200 steps) or ECOG \\\u003C= 1\n* No contraindications to any aspect of participation, including aerobic exercise\n* Participant must be able to read, write, and understand the English language and be able to provide written consent\n* Participant must understand the investigational nature of this study and sign an Independent Ethics Committee\u002FInstitutional Review Board approved written informed consent form prior to receiving any study related procedure\n\nExclusion Criteria:\n\n* Known clinically significant severe chronic obstructive pulmonary disease (COPD), ischemic heart disease, congestive heart failure, and\u002For significant cardiac arrhythmias\n* Limiting orthopedic, musculoskeletal or psychological conditions (clinician discretion)\n* Overall medical frailty (clinician discretion)\n* Any condition contraindicating additional blood collection beyond standard of care\n* Unwilling or unable to follow protocol requirements\n* Any condition which in the investigator's opinion deems the participant an unsuitable candidate to receive study intervention","MALE","18 Years",{"count":18,"type":19},50,"ESTIMATED","INTERVENTIONAL",[22],"NA","This trial studies how well nutrition and exercise interventions work in reducing androgen deprivation therapy-induced obese frailty in prostate cancer survivors. Individualized nutrition and exercise advice for prostate cancer patients on androgen deprivation therapy may help to reduce obese frailty and change the levels of myokines in blood.",[25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44],"Cancer Survivor","Obesity","Overweight","Prostate Adenocarcinoma","Stage A Prostate Cancer","Stage B Prostate Cancer","Stage C Prostate Cancer","Stage D Prostate Cancer","Stage I Prostate Cancer","Stage II Prostate Cancer","Stage IIA Prostate Cancer","Stage IIB Prostate Cancer","Stage IIC Prostate Cancer","Stage III Prostate Cancer","Stage IIIA Prostate Cancer","Stage IIIB Prostate Cancer","Stage IIIC Prostate Cancer","Stage IV Prostate Cancer","Stage IVA Prostate Cancer","Stage IVB Prostate Cancer","RECRUITING","2026-05-01",{"date":48,"type":49},"2026-05-07","ACTUAL",{"date":51,"type":49},"2019-05-02",{"date":53,"type":19},"2029-05-02",{"name":55,"class":56},"Roswell Park Cancer Institute","OTHER",1,{"id":59,"slug":60,"hasResults":11,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":4,"eligibilityCriteria":64,"healthyVolunteers":11,"sex":65,"minAge":4,"maxAge":4,"enrollmentInfo":66,"targetDuration":4,"studyType":20,"phases":68,"briefSummary":69,"conditions":70,"keywords":79,"overallStatus":81,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":57},"100578450","mindfulness-based-intervention-for-depressive-symptoms-sent-via-text-mindset-100578450","NCT06811454","Mindfulness-based Intervention for Depressive Symptoms Sent Via Text (MINDSET)","A Daily, Digital Mindfulness-Based Intervention for Depressive Symptoms After Serious Medical Illness","Inclusion Criteria:\n\n1. Self-reported mild to moderately-severe symptoms of depression (score 5-19 on PHQ-9).\n2. A diagnosis of stage 0-III breast, prostate, or colorectal cancer.\n3. Completion of primary cancer treatment within 2 years (excludes hormone therapy).\n4. An ability to provide informed consent.\n5. An ability to read and speak English.\n6. Access to a web-enabled device (phone, tablet, computer).\n\nExclusion Criteria:\n\n1. Self-reported minimal and severe depressive symptoms (\\\u003C4 and \\> 20 on PHQ-9).\n2. Self-reported suicidal ideation (\\>1 on item 9 PHQ-9).\n3. Another psychological, medical, or other condition\u002Fissue determined that necessitates priority treatment and\u002For that would interfere with participation (e.g., schizophrenia, borderline personality disorder)\n4. Current or recent substance abuse\u002Fdependence.\n5. Stage IV cancer diagnosis.\n6. A cancer recurrence actively requiring treatment.\n7. Self-reported active mindfulness practice.\n8. Prior participation in a formal mindfulness program (e.g., MBCT, Mindfulness-Based Stress Reduction Program, Mindfulness-Based Cancer Recovery","ALL",{"count":67,"type":19},76,[22],"The purpose of this study is to develop and test a new intervention to reduce depressive symptoms in post-treatment cancer participants.",[71,72,73,74,75,38,34,33,76,77,78],"Depression","Cancer","Stage III Breast Cancer","Stage II Breast Cancer","Stage I Breast Cancer","Stage III Colorectal Cancer","Stage II Colorectal Cancer","Stage I Colorectal Cancer",[80],"Post treatment Depression","NOT_YET_RECRUITING","2026-01-22",{"date":84,"type":49},"2026-01-23",{"date":86,"type":19},"2026-08-03",{"date":88,"type":19},"2029-03-31",{"name":90,"class":56},"Case Comprehensive Cancer Center"]