[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"staphylococcus-aureus-bacteraemia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:staphylococcus-aureus-bacteraemia":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":5},"100571910","phase-4-comparison-of-cloxacillin-and-benzylpenicillin-in-penicillin-susceptible-s-aureus-bacteraemia-100571910",false,"NCT06726395","Comparison of Cloxacillin and Benzylpenicillin in Penicillin Susceptible S. Aureus Bacteraemia","Randomized Controlled Clinical Trial Comparing Treatment With Cloxacillin Versus Benzylpenicillin in Bacteraemia Caused by Penicillin-susceptible Staphylococcus Aureus (PSSA)","COMeBAC","Inclusion Criteria:\n\nAged ≥18 with penicillin susceptible S. aureus bacteraemia (PSSA), and able to provide written informed consent.\n\nExclusion Criteria:\n\n* allergy to penicillin,\n* inability to give informed consent,\n* concomitant growth of other clinically significant bacteria in blood cultures\n* neutropenia\n\n  -≥ 96h with prior antibiotics\n* When the per oral follow up medication can not be flukloxacillin or penicillinV\u002FAmoxicillin (ie prosthetic joint infection)\n* Patients in terminal palliation, where death is expected within 7 days.\n* Where the treating physician believes cloxacillin is not a first-line treatment.","ALL","18 Years",{"count":20,"type":21},420,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","The goal of this study is to investigate if benzylpenicillin is a better treatment option than cloxacillin in patients with penicillin-susceptible Staphylococcus aureus bacteraemia.",[27,28,29,30],"Staphylococcus Aureus Bacteraemia","Staphylococcal Bacteraemia","Staphylococcus Aureus Bloodstream Infections (BSI; Bacteremia)","Staphylococcus (S.) Aureus Infection",[32,33,34,35,36],"Penicillin treatment","benzylpenicillin","cloxacillin","Penicillin susceptible S. aureus","Staphylococcus aureus bacteraemia","RECRUITING","2026-04-24",{"date":40,"type":41},"2026-04-30","ACTUAL",{"date":43,"type":41},"2025-03-10",{"date":45,"type":21},"2028-07",{"name":47,"class":48},"Region Skane","OTHER"]