[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"statin-associated-myopathy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:statin-associated-myopathy":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":34,"leadSponsor":36,"locationsCount":4},"100580244","evaluation-of-neuromuscular-blockade-responses-in-statin-using-and-non-using-patients-100580244",false,"NCT06834776","Evaluation of Neuromuscular Blockade Responses in Statin-Using and Non-Using Patients","Evaluation of Neuromuscular Blockade Responses in Statin-Using and Non-Using Patients Undergoing Elective Surgery Under General Anesthesia, Monitored by Train-of-Four (TOF)","Inclusion Criteria:\n\n* Age 18-75 years\n* ASA classification I, II, III\n* BMI 18-30\n* Statin use for at least 3 months or no prior statin use\n* Elective surgery requiring general anesthesia with endotracheal intubation\n* Signed informed consent for participation in the study\n\nExclusion Criteria:\n\n* ASA classification IV or higher\n* BMI \\\u003C18 or \\>30\n* History of liver or renal insufficiency (creatinine \\>1.6, liver function tests \\>2x normal)\n* Neuromuscular, psychiatric, or neurological disorders\n* Pregnancy\n* Use of drugs affecting neuromuscular function (e.g., anticonvulsants, aminoglycosides)\n* History of malignant hyperthermia\n* Respiratory disorders, including sleep apnea\n* Allergy to anesthetic drugs used in the study","ALL","18 Years","75 Years",{"count":20,"type":21},104,"ESTIMATED","OBSERVATIONAL","This study aims to compare the neuromuscular blockade responses in patients undergoing elective surgery under general anesthesia, with a focus on the use of statins. The study will assess the depth of neuromuscular blockade, recovery time, and postoperative residual curarization using Train-of-Four (TOF) monitoring, with the primary goal of determining whether statin use alters the neuromuscular blockade management.",[25,26,27],"Neuromuscular Blockade","Statin-Associated Myopathy","Neuromuscular Monitoring","NOT_YET_RECRUITING","2025-02-15",{"date":31,"type":32},"2025-02-19","ACTUAL",{"date":29,"type":21},{"date":35,"type":21},"2025-12-15",{"name":37,"class":38},"Ankara City Hospital Bilkent","OTHER"]