[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"stellate-ganglion-block\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:stellate-ganglion-block":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,43,73,96,123,149],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100641500","stellate-ganglion-block-and-prognosis-of-neurological-function-after-subarachnoid-hemorrhage-100641500",false,"NCT07652749","Stellate Ganglion Block and Prognosis of Neurological Function After Subarachnoid Hemorrhage","Effect of Stellate Ganglion Block on the Prognosis of Neurological Function After Subarachnoid Hemorrhage","Inclusion Criteria:\n\n* Age range: 18-65 years old;\n* Within 72 hours after onset of aSAH,and planning surgical treatment(aneurysm embolizing or clipping);\n* Preoperative Hunt-Hess grade 2-3\n* Sign informed consent.\n\nExclusion Criteria:\n\n* ASA \\> grade IV;\n* Patients with posterior circulation aneurysm;\n* Patients with severe systemic hemorrhagic diseases;\n* Patients with trauma and local infection in the nerve block area;\n* Local anatomic structure changes (neck structure changes caused by radiotherapy, chemotherapy and surgery);\n* Allergy to known local anesthetics;\n* Pregnant and lactating women.","ALL","18 Years","65 Years",{"count":20,"type":21},560,"ESTIMATED","INTERVENTIONAL",[24],"NA","The incidence of cerebral vasospasm after aneurysm subarachnoid hemorrhage (aSAH) is as high as 70%; cerebral vasospasm（CVS） is closely related to delayed cerebral ischemia （DCI）, which is one of the important reasons for poor outcomes in patients with aSAH.\n\nIn recent years, it has been reported that stellate ganglion block(SGB) can effectively alleviate cerebral vasospasm(CVS), reduce cerebral blood flow velocity and increase cerebral perfusion in patients with aneurysm subarachnoid hemorrhage(aSAH)。However, whether the alleviation of CVS after SGB is beneficial to the long-term neurological prognosis has not been confirmed Therefore, a prospective randomized controlled study is needed to further explore the role of SGB block in improving the outcomes of patients with aSAH.",[27,28,29],"Aneurysmal Subarachnoid Hemorrhage","Stellate Ganglion Block","Neurological Prognosis","NOT_YET_RECRUITING","2026-06-11",{"date":33,"type":34},"2026-06-17","ACTUAL",{"date":36,"type":21},"2026-06-15",{"date":38,"type":21},"2029-03-31",{"name":40,"class":41},"Beijing Tiantan Hospital","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":18,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":22,"phases":53,"briefSummary":54,"conditions":55,"keywords":56,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":72},"100635896","effects-of-stellate-ganglion-block-on-delirium-and-circadian-rhythm-in-geriatric-intensive-care-patients-100635896","NCT07558642","Effects of Stellate Ganglion Block on Delirium and Circadian Rhythm in Geriatric Intensive Care Patients","Effects of Stellate Ganglion Block on Delirium and Circadian Rhythm in Geriatric Intensive Care Patients: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged 65 years or older expected to remain in the intensive care unit for more than 48 hours\n* RASS score \\> -4\n\nExclusion Criteria:\n\n* History of neurodegenerative disease (e.g., Alzheimer's disease, dementia, vascular dementia)\n* Uncontrolled psychiatric disorders\n* Alcohol use disorder and\u002For substance abuse\n* History of traumatic brain injury or ischemic\u002Fhemorrhagic cerebrovascular event\n* Severe hearing and\u002For visual impairment\n* Benzodiazepine use\n* Renal failure (Acute Kidney Injury stage 2-3) and\u002For liver failure\n* Beta-blocker use\n* Contraindications to stellate ganglion block (e.g., coagulopathy, glaucoma, recent myocardial infarction)\n* Sepsis\n* Allergy to bupivacaine\n* Inability to communicate in Turkish or English\n* Severe hyponatremia\n* Hemodynamic instability","99 Years",{"count":52,"type":21},130,[24],"Delirium is a common complication in elderly intensive care unit (ICU) patients and is associated with poor clinical outcomes. Circadian rhythm disruption is considered an important contributing factor in delirium development. Stellate ganglion block (SGB) may modulate autonomic nervous system activity and improve circadian rhythm regulation.\n\nThis prospective randomized placebo-controlled trial aims to evaluate the effects of ultrasound-guided stellate ganglion block on delirium incidence and circadian rhythm in ICU patients aged 65 years and older. Delirium will be assessed using validated clinical scales, and circadian rhythm will be evaluated through serial measurements of serum melatonin and plasma cortisol levels",[28],[28,57,58,59,60,61],"Delirium","Intensive Care Unit","Circadian Rhythm","Melatonin","Cortisol","2026-05-11",{"date":64,"type":34},"2026-05-13",{"date":66,"type":21},"2026-05-06",{"date":68,"type":21},"2027-02-01",{"name":70,"class":71},"Antalya Training and Research Hospital","OTHER_GOV",2,{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":80,"targetDuration":82,"studyType":83,"phases":4,"briefSummary":84,"conditions":85,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":42},"100614060","stellate-ganglion-block-on-postoperative-sleep-status-in-patients-with-prolonged-disorders-of-consciousness-100614060","NCT07274683","Stellate Ganglion Block on Postoperative Sleep Status in Patients With Prolonged Disorders of Consciousness","Effect of Stellate Ganglion Block on Postoperative Sleep Status in Patients With Prolonged Disorders of Consciousness: a Single--Centre Cohort Study","Inclusion Criteria:\n\n* Aged 18-65 years;\n* Prolonged disorders of consciousness after acquired brain injury;\n* Scheduled to undergo spinal cord electronic stimulator implantation under general anesthesia;\n* The skull is intact;\n* Informed consent is obtained;\n\nExclusion Criteria:\n\n* Continuous sedation therapy is performed within 72 hours prior to the study;\n* The integrity of brain structure is disrupted due to causes such as open head injury and cerebral parenchymal resection;\n* Decreased intracranial compliance caused by hydrocephalus and other reasons;\n* Airway stenosis or severe dysfunction of ventilation or gas exchange due to various causes;\n* Known or suspected severe cardiac, pulmonary, and renal dysfunction;\n* History of sedative drug allergy;\n* Complicated by other mental or neurological disorders;\n* Local anesthetic allergy;\n* Other reasons for ineligibility in this study;\n* Informed consent is not obtained;",{"count":81,"type":21},25,"6 Months","OBSERVATIONAL","The goal of this clinical trial is to learn about the effect of preoperative administration of stellate ganglion block on postoperative sleep status in patients with prolonged disorders of consciousness. The main aims to answer are: • To explore the effect of preoperative administration of stellate ganglion block on postoperative polysomnography and total sleep time in patients with prolonged disorders of consciousness. • To explore the effect of preoperative administration of stellate ganglion block on postoperative cerebral oxygen saturation, cerebral hemodynamic parameters and recovery of consciousness. Participants will be pDoC patients with intact skulls after acquired brain injury who will undergo spinal cord electronic stimulator implantation under general anesthesia at Beijing Tiantan Hospital. Stellate ganglion block will be administrated before the surgery. Polysomnography, total sleep time, cerebral oxygen saturation, cerebral hemodynamic parameters, CRS-R scores, GCS scores, WHIM scores and NCS scores will be investigated.",[28,86,87],"Prolonged Disorders of Consciousness","Sleep","2025-11-27",{"date":90,"type":34},"2025-12-10",{"date":92,"type":21},"2026-01-01",{"date":94,"type":21},"2027-01-01",{"name":40,"class":41},{"id":97,"slug":98,"hasResults":11,"nctId":99,"briefTitle":100,"officialTitle":101,"acronym":4,"eligibilityCriteria":102,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":103,"targetDuration":4,"studyType":22,"phases":105,"briefSummary":107,"conditions":108,"keywords":111,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":42},"100609191","phase-4-percutaneous-blockade-of-the-stellate-ganglion-in-electrical-storm-100609191","NCT07211347","Percutaneous Blockade of the Stellate Ganglion in Electrical Storm","Percutaneous Blockade Protocol of the Stellate Ganglion in Patients With Refractory Electrical Storm","Inclusion Criteria:\n\n* Patients over 18 years old with structural heart disease and a diagnosis of refractory electrical storm, or those who require discontinuation of antiarrhythmics due to adverse events or contraindications to standard therapy.\n\nExclusion Criteria:\n\n* Patients under 18\n* History of heart transplant or prior cardiac denervation surgery\n* Anatomical contraindications for the procedure (prior neck surgery, burns, large scars, or thyroid goiter).\n* Genetically related polymorphic VT\n* End-stage renal disease on dialysis",{"count":104,"type":21},64,[106],"PHASE4","There is no randomized clinical study in the literature that evaluated the efficacy and safety of the stellate ganglion infiltration procedure in patients with electrical storm. So far, case reports and retrospective studies suggest that such a strategy should be considered in cases refractory to initial therapy. In this scenario, the European and American guidelines for the treatment of ventricular arrhythmias recommend autonomic modulation in this setting, but only with a level of recommendation IIb (1,2). This project aims to evaluate the effect of stellate ganglion infiltration in patients with electric storm refractory to initial clinical measures. It is a randomized clinical trial where patients will receive treatment with a lidocaine and bupivacaine anesthetic solution or no intervention. The effect of the intervention will be considered positive when there is a reduction of arrhythmic events of at least 50% in the 12 hours immediately after.",[109,28,110],"Electrical Storm","Ventricular Arrhythmia",[110,109,112],"Stellate ganglion block","RECRUITING","2025-09-29",{"date":116,"type":34},"2025-10-07",{"date":118,"type":34},"2025-06-06",{"date":120,"type":21},"2028-12",{"name":122,"class":41},"University of Sao Paulo General Hospital",{"id":124,"slug":125,"hasResults":11,"nctId":126,"briefTitle":127,"officialTitle":128,"acronym":4,"eligibilityCriteria":129,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":130,"enrollmentInfo":131,"targetDuration":4,"studyType":22,"phases":133,"briefSummary":134,"conditions":135,"keywords":136,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":42},"100602922","stellate-ganglion-block-in-complex-regional-pain-syndrome-100602922","NCT07129811","Stellate Ganglion Block in Complex Regional Pain Syndrome","The Effect of Ultrasound-Guided Stellate Ganglion Block on Pain, Functionality, and Quality of Life in Type 1 Complex Regional Pain Syndrome in Stroke Patients","Inclusion Criteria:\n\n* Volunteer male and female patients aged 18-75\n* Diagnosed with Complex Regional Pain Syndrome according to the IASP 2012 Diagnostic Criteria\n* Patient's pain level must be VAS \\>4\n\nExclusion Criteria:\n\n* Presence of existing neurological diseases other than rheumatic diseases and stroke\n* General impairment\n* Conditions that would constitute a contraindication to application, such as an open wound or sensory deficit in the application area\n* Presence of active infection\n* Presence of malignancy\n* Cognitive dysfunction (mini mental test result \\\u003C23)","75 Years",{"count":132,"type":21},32,[24],"The aim was to investigate the effect of Stellate Ganglion Blockade, which will be applied in addition to conventional physical therapy, on pain and functionality in patients with poststroke complex regional pain syndrome.",[28],[137,138,139],"Stroke","chronic pain","Complex regional pain syndrome","2025-08-29",{"date":142,"type":34},"2025-09-05",{"date":144,"type":34},"2025-01-15",{"date":146,"type":21},"2025-10-31",{"name":148,"class":41},"Ankara City Hospital Bilkent",{"id":150,"slug":151,"hasResults":11,"nctId":152,"briefTitle":153,"officialTitle":154,"acronym":4,"eligibilityCriteria":155,"healthyVolunteers":156,"sex":16,"minAge":17,"maxAge":157,"enrollmentInfo":158,"targetDuration":4,"studyType":22,"phases":160,"briefSummary":161,"conditions":162,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":164,"lastUpdatePostDateStruct":165,"startDateStruct":167,"completionDateStruct":169,"leadSponsor":171,"locationsCount":42},"100557607","efficacy-safety-and-neural-mechanism-of-stellate-ganglion-block-in-the-treatment-of-anxiety-disorder-100557607","NCT06540313","Efficacy, Safety and Neural Mechanism of Stellate Ganglion Block in the Treatment of Anxiety. Disorder.","Efficacy, Safety and Neural Mechanism of Stellate Ganglion Block in the Treatment of Anxiety.","Inclusion Criteria:\n\n1. Aged 18-60 years old\n2. Diagnosed with various types of anxiety disorders according to the DSM-5, and meet the diagnostic criteria for pain disorders\n3. Right-handed\n4. Voluntarily join the study and sign the informed consent.\n\nExclusion Criteria:\n\n1. Suicidal thoughts and behaviors\n2. serious physical disease\n3. diseases of the nervous system or other mental diseases\n4. Contraindications for MRI examination\n5. During pregnancy or lactation\n6. Allergy to narcotic drugs\n7. Contraindications with stellate ganglion block",true,"60 Years",{"count":159,"type":21},60,[24],"1. In this study, ultrasound-guided Stellate Ganglion Block(SGB) will be used in the treatment of anxiety disorders, combined with relevant scales, HRV indicators and resting state functional magnetic resonance data, to explore the safety and effectiveness of SGB in the treatment of anxiety disorders, and to explore whether its mechanism of action is related to the excitability of sympathetic nervous system and the activity changes of insular cortex.\n2. Verify the following hypothesis:\n\n(1) SGB is a safe, well-tolerated and acceptable treatment technique; (2) After SGB treatment, the anxiety symptoms of the patients were relieved to a certain extent and the psychological function was restored; (3) The sympathetic excitability of patients after SGB treatment is reduced, and this effect can be monitored by heart rate variability; (4) The activity of insular cortex decreased after SGB treatment.",[163,28],"Anxiety Disorders","2024-08-01",{"date":166,"type":34},"2024-08-06",{"date":168,"type":21},"2024-09-01",{"date":170,"type":21},"2026-06-10",{"name":172,"class":41},"Nanjing Medical University"]