[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"stereoscopic-vision\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:stereoscopic-vision":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":4},"100635052","effectiveness-of-tdcs-in-paediatric-amblyopia-100635052",false,"NCT07547670","Effectiveness of tDCS in Paediatric Amblyopia.","tDCS","Inclusion Criteria:\n\n* Children aged 4-14 years.\n* Strabismic amblyopia resistant to patching (PEDIG criteria).\n* Anisometropic amblyopia resistant to patching (PEDIG criteria).\n\nExclusion Criteria:\n\n* Ocular pathology.\n* Nystagmus.\n* Mental disability.\n* Cognitive delay.\n* Neurological problems incompatible with treatment.\n* Pacemakers.\n* Intracranial electrodes.\n* Implanted defibrillators.\n* Cranial pathologies.\n* Cranial lesions.\n* Withdrawal will occur upon adverse events, protocol deviation, refusal, or loss to follow-up.","ALL","4 Years","14 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this randomized, double-blind clinical trial is to determine whether transcranial direct current stimulation (tDCS) can effectively and safely improve vision in children aged 4-14 years with strabismic or anisometropic amblyopia that has not responded to conventional patching therapy.\n\nThe main questions it aims to answer are:\n\nDoes tDCS produce significant and sustained improvements in visual acuity, contrast sensitivity, and stereopsis in children with amblyopia?\n\nIs tDCS a safe, well-tolerated, and faster alternative or complementary treatment compared with standard occlusion therapy?\n\nDoes tDCS induce functional and structural changes in the visual cortex associated with increased neuroplasticity, including modulation of GABAergic activity?\n\nIf there is a comparison group:\n\nResearchers will compare active tDCS with sham (placebo) stimulation to see if active treatment leads to greater visual recovery and cortical changes than placebo.\n\nParticipants will:\n\nReceive several sessions of active or sham tDCS using low-intensity electrical stimulation applied to visual brain areas.\n\nUndergo standard visual assessments, including visual acuity, contrast sensitivity, and stereopsis.\n\nComplete neurophysiological and neuroimaging evaluations (EEG, pattern visual evoked potentials, and functional MRI).\n\nProvide biochemical measures related to GABA levels.\n\nThis study aims to validate tDCS as a non-invasive, child-friendly, and effective therapy that may overcome the limitations of patching and support its inclusion in paediatric clinical practice.",[27,28,29,30],"Amblyopia","Amblyopia Strabismic","Visual Acuity","Stereoscopic Vision",[14,32],"Ambyopia","NOT_YET_RECRUITING","2026-04-23",{"date":36,"type":37},"2026-04-29","ACTUAL",{"date":39,"type":21},"2026-06-01",{"date":41,"type":21},"2029-08-31",{"name":43,"class":44},"Universidad de Murcia","OTHER"]