[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"stone-ureter\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:stone-ureter":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,39,68,96,120,142],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":4},"100638125","application-of-traditional-chinese-medicine-five-element-music-therapy-combined-with-acupoint-patch-therapy-based-on-the-holistic-mind-body-treatment-theory-in-upper-urinary-tract-calculi-treated-with-ureteroscopic-lithotripsy-under-local-anesthesia-100638125",false,"NCT07607626","Application of Traditional Chinese Medicine Five-Element Music Therapy Combined With Acupoint Patch Therapy Based on the \"Holistic Mind-Body Treatment\" Theory in Upper Urinary Tract Calculi Treated With Ureteroscopic Lithotripsy Under Local Anesthesia","Inclusion Criteria:\n\n1. Age 18 years or older.\n2. Computed tomography confirmed diagnosis of upper urinary tract calculi.\n3. Stone size less than 2 cm in maximum diameter.\n4. Scheduled to undergo primary ureteroscopic lithotripsy.\n5. Normal hearing ability.\n6. Willing and able to provide written informed consent.\n\nExclusion Criteria:\n\n1. Congenital malformation of the urinary system\n2. History of allergy to local anesthetics\n3. Mental disorder that precludes cooperation with the surgical procedure\n4. Uncontrolled urinary tract infection before surgery\n5. Pregnancy\n6. Pre-existing chronic pain syndrome or long-term use of analgesic medications\n7. Long-term use of anti-anxiety medications -","ALL","18 Years",{"count":18,"type":19},60,"ESTIMATED","INTERVENTIONAL",[22],"NA","This study aims to evaluate whether the combination of Traditional Chinese Medicine Five-Element Music Therapy and acupoint patch therapy can effectively reduce intraoperative pain and anxiety in patients undergoing ureteroscopic lithotripsy for upper urinary tract calculi under local anesthesia, compared to conventional local anesthesia alone.",[25,26],"Stone;Renal","Stone Ureter","NOT_YET_RECRUITING","2026-05-19",{"date":30,"type":31},"2026-05-26","ACTUAL",{"date":33,"type":19},"2026-06",{"date":35,"type":19},"2027-07",{"name":37,"class":38},"Li Fang","OTHER",{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":4,"eligibilityCriteria":45,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":46,"targetDuration":4,"studyType":20,"phases":48,"briefSummary":49,"conditions":50,"keywords":52,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":67},"100505799","stent-omission-after-ureteroscopy-and-lithotripsy-in-the-michigan-urological-surgery-improvement-collaborative-100505799","NCT05866081","Stent Omission After Ureteroscopy and Lithotripsy in the Michigan Urological Surgery Improvement Collaborative","Stent Omission After Ureteroscopy and Lithotripsy in the Michigan Urological Surgery Improvement Collaborative (SOUL MUSIC)","Inclusion Criteria:\n\n* Undergoing unilateral ureteroscopy and lithotripsy for stone disease (participants may have contralateral stones, as long as these are asymptomatic and not being treated concurrently)\n* Largest stone less or equal to 10 millimeter in size as measured on abdominal x-ray, ultrasound, or computed tomography scan\n* Access to means of communication with the study team (email, text messaging, and\u002For telephone)\n* Adequate independent cognitive function and English language proficiency to complete study surveys\n* Written informed consent\n\nExclusion Criteria:\n\n* Planned bilateral ureteroscopy\n* Indwelling ureteral stent or percutaneous nephrostomy tube preoperatively in either kidney\n* Anatomic abnormalities of the ipsilateral upper urinary tract (for example, horseshoe kidney, crossed fused ectopia, pelvic kidney, urinary diversion)\n* Anatomic or functional solitary kidney\n* Planned secondary or staged ureteroscopy\n* Planned use of ureteral access sheath\n* Pregnancy\n* Patients who use opiate medication daily for greater than 3 months to manage a painful condition\n\nSecond Stage Exclusion Criteria:\n\n* ureteral perforation\n* unanticipated anatomic abnormality\n* greater than expected bleeding\n* ureteral dilation greater than 12 French\n* ureteral access sheath utilized\n* failed ureteroscopy\n* no or incomplete lithotripsy performed\n* unable to complete case due to medical or anesthetic event.",{"count":47,"type":19},792,[22],"This is a multicenter prospective trial with randomized and observational cohorts assessing patient-reported outcomes and unplanned healthcare utilization following ureteroscopic treatment of renal and ureteral stones, with placement versus omission of a ureteral stent.\n\nEligible participants in the randomization trial will be randomized to ureteroscopy with stent placement or stent omission.\n\nEligible participants that consent to the observational only cohort will complete surveys and the treating physicians will decide the treatment options for the participants.\n\nThe study team hypothesizes that:\n\n* Pain interference change from pre-surgery to Day 7-10 will differ between the two treatment arms. This hypothesis will be evaluated separately in the randomized and observational cohorts.\n* Unplanned healthcare utilization in the treatment arms will have different unplanned healthcare utilization ranks leading to a win proportion significantly higher or lower than 0.5 in the stent omission arm compared to the stent placement arm. This hypothesis will be evaluated separately in the randomized and observational cohorts.",[51,26],"Stone, Kidney",[53,54,55,56],"Unilateral ureteroscopy and lithotripsy","Ureteral stent","Pain assessment","Quality of life","RECRUITING","2025-12-08",{"date":60,"type":31},"2025-12-15",{"date":62,"type":31},"2023-06-01",{"date":64,"type":19},"2026-05-01",{"name":66,"class":38},"University of Michigan",16,{"id":69,"slug":70,"hasResults":11,"nctId":71,"briefTitle":72,"officialTitle":72,"acronym":4,"eligibilityCriteria":73,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":74,"targetDuration":4,"studyType":20,"phases":76,"briefSummary":77,"conditions":78,"keywords":81,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":95},"100572105","efficacy-of-intra-ureteric-aminophylline-installation-after-failed-stone-accessibility-by-semi-rigid-ureteroscopy-prospective-trial-100572105","NCT06728943","Efficacy of Intra-Ureteric Aminophylline Installation After Failed Stone Accessibility by Semi-rigid Ureteroscopy. Prospective Trial","Inclusion Criteria:\n\n* The study will include patients with failed stone accessibility by semi-rigid ureteroscopy.\n\nExclusion Criteria:\n\n* Child age group\n* Pre stented patients\n* Contraindications to aminophylline (hypersensitivity to drug components, pregnancy or lactation ,…)\n* Contraindications to ureteroscopy (active urinary tract infection - Contraindications to general or spinal anesthesia - Uncorrected bleeding disorders)",{"count":75,"type":19},300,[22],"In this study we will test the effect of local intraureteric aminophylline instillation through Ureteric stent and Reaching stone without the need of ballon dilataion",[79,26,80],"Ureterocopic Lithotripsy","Ureteric Stone",[82,83,84,85],"ureteroscopy","stone ureter","ureteral dilatation","failed ureteroscopy","2024-12-08",{"date":88,"type":31},"2024-12-11",{"date":90,"type":31},"2024-12-01",{"date":92,"type":19},"2028-12-01",{"name":94,"class":38},"Al-Azhar University",1,{"id":97,"slug":98,"hasResults":11,"nctId":99,"briefTitle":100,"officialTitle":100,"acronym":4,"eligibilityCriteria":101,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":102,"targetDuration":4,"studyType":20,"phases":104,"briefSummary":105,"conditions":106,"keywords":107,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":4},"100571626","eswl-vs-flexible-uretroscopy-in-management-of-upper-ureteric-stones-a-prospective-randomized-study-100571626","NCT06722703","ESWL vs Flexible Uretroscopy in Management of Upper Ureteric Stones a Prospective Randomized Study","Inclusion Criteria:\n\n* patients age\\>18 years old. Stone site: upper ureteric stone. Stone side: unilateral stones Stone size: stones diameter up to 1cm Stone number: single or multiple Radio-opaque stone\n\nExclusion Criteria:\n\n* patients with solitary kidney or only function kidney renal impairment present of distal obstruction pregnancy, current breast feeding. Bleeding tendency or anticoagulation. ipsilateral ureterolithiasis, Acute or chronic nephritis, or Renal tuberculosis aneurysm of the aorta or renal artery. inability to position the patient on the SWL table (eg, due to severe skeletal deformity or morbid obesity).\n\nradiolucent stones that are not visible on ultrasound. severe metabolic disturbances (eg, cystinuria, primary hyperparathyroidism, or renal tubular acidosis)",{"count":103,"type":19},42,[22],"This comparison between ESWL and flexible ureteroscopy aims to explore the efficacy, safety, and outcomes of these treatments for upper ureteric stones under 15 mm, focusing on stone-free rates, procedural risks, recovery times, and recurrence rates. A thorough understanding of these techniques is essential for optimizing patient outcomes and personalizing treatment strategies.\n\nstudy aim to evaluate the effectiveness, safety, and cost of SWL compared to flexible uretroscopy in management patients with upper ureteric stone less than 15 mm in size",[26],[108,109,110],"upper ureteric stones","ESWL","flexible uretroscopy","2024-12-04",{"date":113,"type":31},"2024-12-09",{"date":115,"type":19},"2025-01-01",{"date":117,"type":19},"2026-02-01",{"name":119,"class":38},"Assiut University",{"id":121,"slug":122,"hasResults":11,"nctId":123,"briefTitle":124,"officialTitle":125,"acronym":4,"eligibilityCriteria":126,"healthyVolunteers":11,"sex":15,"minAge":4,"maxAge":4,"enrollmentInfo":127,"targetDuration":4,"studyType":129,"phases":4,"briefSummary":130,"conditions":131,"keywords":132,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":134,"lastUpdatePostDateStruct":135,"startDateStruct":137,"completionDateStruct":139,"leadSponsor":141,"locationsCount":95},"100561615","outcome-of-urs-in-fresh-versus-recurrent-cases-of-stone-ureter-100561615","NCT06592469","Outcome of URS in Fresh Versus Recurrent Cases of Stone Ureter","The Outcome of Ureteroscopy in Fresh Versus Recurrent Cases of Stone Ureter (Post-ESWL, Endoscopy, or Open Surgery)","Inclusion Criteria:\n\n* • all cases with middle and lower ureteric stone candidate for endoscopy.\n\n  * Stone 15mm or less.\n\nExclusion Criteria:\n\n* • Patients with a ureteral stent.\n\n  * Patient refusing participation.\n  * Pregnant woman.\n  * Active urinary tract infection.\n  * Comorbidities prevent intervention including bleeding tendency or uncorrectable coagulation profile.",{"count":128,"type":19},80,"OBSERVATIONAL","Comparison of Ureteroscopy in fresh versus recurrent cases of stone ureter",[26],[133],"URS","2024-09-11",{"date":136,"type":31},"2024-09-19",{"date":138,"type":19},"2024-10-01",{"date":140,"type":19},"2025-11",{"name":119,"class":38},{"id":143,"slug":144,"hasResults":11,"nctId":145,"briefTitle":146,"officialTitle":146,"acronym":4,"eligibilityCriteria":147,"healthyVolunteers":148,"sex":15,"minAge":16,"maxAge":149,"enrollmentInfo":150,"targetDuration":4,"studyType":20,"phases":151,"briefSummary":153,"conditions":154,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":4},"100551629","early-phase-1-extra-corporeal-shock-wave-lithotripsy-for-renal-and-upper-ureteral-stones-in-adults-under-locally-infiltrate-d-anaesthetics--a-clinical-randomized-controlled-study-100551629","NCT06462573","Extra-Corporeal Shock Wave Lithotripsy for Renal and Upper Ureteral Stones in Adults Under Locally Infiltrate d Anaesthetics ; a Clinical Randomized Controlled Study","Inclusion Criteria:\n\n* Patients aged 18 years or older whether males or females with renal or upper ureteric stone(s) candidate for ESWL therapy 2. Renal stones should be between 1- 2 cm and upper ureteric stones should be less than 15 mm\n\nExclusion Criteria:\n\n* 1.. Patients refusing to participate in the study or patients not compliant with follow up 2. Renal stones in ectopic kidneys 3. Radiolucent upper ureteric stones 4. Patients with myo-skeletal deformities e.g. kyphoscoliosis",true,"75 Years",{"count":18,"type":19},[152],"EARLY_PHASE1","There are many treatment modalities available for managing renal and upper ureteric stones. They range from completely non-invasive outpatient procedures to invasive procedures requiring hospital admission and increased risks of complications. Extracorporeal shockwave lithotripsy (ESWL) is a truly non-invasive procedure as opposed to other surgical treatments used, such as retrograde intrarenal surgery and percutaneous nephrolithotomy (1).\n\nThe choice between shockwave lithotripsy (SWL) and other treatment modalities depends on several factors, including stone site, stone burden, stone CT density, etc. Another compounding factor in choosing the treatment modality is patient preference and expectation (1).\n\nExtracorporeal Shock Wave Lithotripsy is one of the treatment options for patients with renal and ureteral calculi. Even though the procedure is less invasive compared to others. Pain caused by the procedure is a major concern. Several studies recommended the use of either local or systemic analgesia with varying results (2).\n\nAs a truly non-invasive treatment option, ESWL has been widely used for treating renal, as well as ureteric, stones with satisfactory efficacy and minimal morbidity. However, the pain caused by ESWL is a major limitation of its efficacy, in addition to the associated patient dissatisfaction and negative experience that may result in the patient refraining from further sessions.\n\nThe relationship between pain and ESWL efficacy can be explained by multiple facts: firstly, the pain leads to inability to increase the energy delivered by the shockwaves to optimum levels; secondly, the pain usually leads to significant movement of the patient, as well as excessive respiratory movements, both of which move the stone away from the focus of shockwaves; lastly, the pain may be severe that the session is discontinued before delivery of effective number of shockwaves",[26],"2024-06-12",{"date":157,"type":31},"2024-06-17",{"date":159,"type":19},"2024-09-01",{"date":161,"type":19},"2026-09-01",{"name":119,"class":38}]