[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"stone-urinary\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:stone-urinary":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,51],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100615688","fans-furs-vs-suction-mini-pcnl-for-2-3-cm-renal-stones-a-multicenter-randomized-trial-100615688",false,"NCT07295860","FANS-FURS vs Suction Mini-PCNL for 2-3 cm Renal Stones: A Multicenter Randomized Trial","A Multicenter Randomized Trial Comparing FANS-Based Flexible Ureteroscopy Versus Suction Mini-Percutaneous Nephrolithotomy for Renal Stones 2-3 cm. The National Innovative Large Egyptian (NILE) Stone Study.","NILE","Inclusion Criteria:\n\n* Adults ≥18 years old.\n* Single or multiple renal stones measuring 2 -3 cm (diagnosed by NCCT).\n* Negative urine culture prior to surgery.\n* Suitable for general\u002Fspinal anesthesia.\n* Signed informed consent.\n\nExclusion Criteria:\n\n* Active urinary tract infection.\n* Anomalous renal anatomy (e.g., horseshoe kidney).\n* Severe ureteral strictures preventing retrograde access.\n* Coagulopathy or inability to discontinue anticoagulation.","ALL","18 Years",{"count":20,"type":21},254,"ESTIMATED","INTERVENTIONAL",[24],"NA","This multicenter, prospective, randomized clinical trial compares FANS-assisted flexible ureteroscopy (FURS) with suction-assisted mini-percutaneous nephrolithotomy (mini-PCNL) for the treatment of renal stones measuring 2-3 cm. A total of 280 patients will be enrolled across nine tertiary centers and randomized 1:1 to either technique. The primary endpoint is stone-free rate (SFR) at 1 month, assessed by non-contrast CT. Secondary outcomes include operative time, intraoperative complications, postoperative morbidity (Clavien-Dindo), pain scores, hospital stay, reinterventions, and quality of life (EQ-5D-5L). The study aims to provide the first high-quality head-to-head evidence comparing these two modern suction-enhanced technologies, with the goal of defining the optimal minimally invasive approach for medium-sized renal stones.",[27,28],"Stone, Kidney","Stone, Urinary",[30,31,32,33,34,35,36,37],"Renal stones","Nephrolithiasis","Urolithiasis","RIRS","FANS","mini-PCNL","Suction technology","Stone-free rate","NOT_YET_RECRUITING","2025-12-19",{"date":41,"type":42},"2025-12-26","ACTUAL",{"date":44,"type":21},"2026-01-01",{"date":46,"type":21},"2027-03-01",{"name":48,"class":49},"Mansoura University","OTHER",9,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":61,"briefSummary":62,"conditions":63,"keywords":4,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":76},"100616531","comparison-between-two-methods-for-renal-stone-treatment-mini-percutaneous-nephrolithotomy-and-flexible-ureteroscopy-with-suction-sheath-100616531","NCT07306819","Comparison Between Two Methods for Renal Stone Treatment Mini Percutaneous Nephrolithotomy and Flexible Ureteroscopy With Suction Sheath","Flexible Ureteroscopy Using a Tip-Bendable Suction Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotomy for the Treatment of 2-3 cm Renal Stones: A Randomized Controlled Trial","mini-PCNL\u002FFANS","Inclusion Criteria:\n\n* Adult patients aging 18 years old or more.\n* Patients with renal stones between 2-3 cm in size confirmed by CT scan.\n\nExclusion Criteria:\n\n* Patients with previous ureteric injury.\n* Patients with uncontrolled diabetes mellitus or hypertension.\n* Patients with uncontrolled hepatic dysfunction.\n* Patients with uremia or renal failure.\n* Pregnant patients.\n* patients with active urinary tract infection.\n* Patients with bleeding tendency or uncontrolled coagulopathy.\n* Patients with congenital anomalies as horse-shoe kidney and pelvi-ureteric junction obstruction.",{"count":60,"type":21},120,[24],"This study aims to compare the efficacy and safety of two modern, minimally invasive surgical techniques for the removal of kidney stones: Mini-Percutaneous Nephrolithotomy (Mini-PCNL) and Flexible Ureteroscopy (FURS) with Flexible and navigable suction sheath\n\nThe primary objective is to determine which procedure results in a higher stone-free rate, as measured by post-operative imaging. Secondary objectives include comparing operative time, hospitalization length andcomplication rates between the two treatment groups.\n\nPatients with two to three centimeter kidney stones who are candidates for either procedure will be randomly assigned to undergo either Mini-PCNL or suctioning FURS. The outcomes will be critically assessed to help establish a higher level of evidence for guiding surgical management of kidney stones.",[64,28,27,65],"Stone;Renal","Stone Clearance","RECRUITING","2025-12-13",{"date":69,"type":42},"2025-12-29",{"date":71,"type":42},"2025-10-15",{"date":73,"type":21},"2026-09-15",{"name":75,"class":49},"Ain Shams University",1]