[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"stress-and-anxiety\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:stress-and-anxiety":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,50,85,113],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100544195","effects-of-walking-in-greenspace-and-the-built-environment-in-adults-with-prediabetes-a-randomized-crossover-trial-100544195",false,"NCT06365723","Effects of Walking in Greenspace and the Built Environment in Adults With Prediabetes: A Randomized Crossover Trial","Inclusion Criteria:\n\n* 25-64 years old.\n* Classified as overweight or obese with BMI 20.0-39.9 kg\u002Fm2 per self-report and a BMI of 20.0- 41.9 kg\u002Fm2 upon actual measure.\n* Documentation\\* of a PreD diagnosis within one year of enrollment by physician or primary care provider based on lab tests showing a fasted blood glucose of 100-125 mg\u002FdL, a 2-hour oral glucose tolerance test of 140-199 mg\u002FdL, or an HbA1c level of 5.7%-6.49%271; OR a study screening lab value of HbA1C within the aforementioned range.\n* Currently engaged in ≤100 min\u002Fweek of moderate to vigorous exercise -confirmed via a 7-day activity recall.\n* No exercise contraindications as assessed by the Physical Activity Readiness Questionnaire (PAR-Q) -this Questionnaire involves seven \"yes\" or \"no\" questions regarding an individual's health status. Answering \"yes\" to any one of these questions may require a prospective participant to acquire a written doctor's note stating they can safely participate in the trial's exercise intervention. The participant would not be enrolled until this doctor's note is received.\n* Stable weight over the last 3 months (less than 10% change).\n* Not currently pregnant, planning to become pregnant, or currently breastfeeding.\n* Willing to maintain current dietary and exercise habits, aside from any changes to be made per the study exercise protocol.\n* Must own a smartphone and be willing and able to download the Garmin Connect app\n* Ability to speak and understand English.\n* Any level of income\n* Any race\u002Fethnicity\n\nExclusion Criteria:\n\n* Individuals \\\u003C25 or \\>64: younger individuals may have not yet reached physiological maturity and in whom PreD prevalence is low; older individuals are more likely to have contraindications to PA and other comorbidities.\n* BMI \\\u003C20 or ≥42.\n* Individuals with an HbA1c level \\\u003C5.7% or \\>6.4%.\n* Currently engaged in \\>100 min\u002Fwk of PA.\n* Individuals with contraindications to exercise participation as indicated by the PAR-Q.\n* A self-reported physical\u002Fmental disability that would prevent them from being able to adhere to the intervention.\n* Past or current diagnosis of Diabetes (Type 1, 1.5 or 2) or use of diabetic medications (e.g. medications to control blood sugar)\n* Any history of a cardiovascular disease event (e.g. heart attack, ablation, pacemaker, stroke)\n* Current treatment for cancer or heart disease (lipid and hypertensive medications acceptable but will be tracked closely).\n* Any change within the last 3 months, or anticipated changes, of any medications that would affect study outcomes (e.g. medications for lipids, blood pressure, anxiety, depression)\n* The use of any medication that significantly interferes with the autonomic nervous system\n* Current tobacco or nicotine users, or those who have quit within the last six months\n* Excessive alcohol (on average\\>1 drinks\u002Fday for women and \\>2 drinks\u002Fday for men) or excessive recreational drug use (reported usage of once a week or more).\n* Unstable weight over the last three months (\\>10% change).\n* Those with major surgery planned or recent history of bariatric surgery (within last 2 years) or a history of other medical interventions that would interfere with study outcomes\n* Currently within one-year postpartum, currently pregnant, or planning to become pregnant during the study period.\n* Currently breastfeeding.\n* Unwilling to comply with study randomization procedures.\n* Unwilling to maintain current dietary and exercise habits, aside from any changes to be made per the study exercise protocol.\n* Current participation in another interventional clinical trial.\n* Previous randomization in this study.","ALL","25 Years","64 Years",{"count":19,"type":20},216,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this randomized crossover trial is to compare the differences in psychological and physiological effects of walking in two different outdoor environments (urban\u002Fsuburban commercial environments vs. urban\u002Fsuburban nature areas\u002Fpreserves) in adults with prediabetes. The main questions it aims to answer are:\n\n* Do psychological measures of stress, anxiety, and affect improve more in one type of outdoor environment over the other?\n* Do physiological measures of stress improve more in one type of outdoor environment over the other?\n\nAs this is a crossover trial, participants will serve as their own controls. Researchers will compare both the psychological and physiological effects walking in the two types of outdoor environments.\n\nParticipants will:\n\n* Walk 150-minutes per week for six weeks in each of the two outdoor conditions.\n* Visit the clinic four times, including before and after each six-week walking period.\n* Collect saliva samples immediately proceeding or following the four clinic visits.\n* Return to their pre-study level of physical activity for a 5-week washout period between each of the two walking interventions.",[26,27,28,29],"PreDiabetes","Heart Rate Variability (HRV)","Stress and Anxiety","Stress Biomarkers",[31,32,33,34,35,36],"walking intervention","built environment","outdoor environment","prediabetes","stress","urban","RECRUITING","2026-06-16",{"date":40,"type":41},"2026-06-18","ACTUAL",{"date":43,"type":41},"2024-06-06",{"date":45,"type":20},"2028-11-30",{"name":47,"class":48},"University of Minnesota","OTHER",3,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":58,"minAge":59,"maxAge":4,"enrollmentInfo":60,"targetDuration":4,"studyType":21,"phases":62,"briefSummary":63,"conditions":64,"keywords":69,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":84},"100637032","effects-of-mindful-eating-on-female-nutrition-students-100637032","NCT07573410","Effects of Mindful Eating on Female Nutrition Students","Efficacy of a Mindful Eating Intervention on Eating Behavior, Body Image, and Mental Health in Female Nutrition Students: a Pilot Randomized Clinical Trial","Inclusion Criteria:\n\n* Female gender\n* Active enrollment in the Nutrition undergraduate program at the time of data collection\n* Agreement to participate in the study\n\nExclusion Criteria:\n\n* Diagnosis of severe cognitive or mental disorders; Regular practice (at least once a week in the last six months) of meditation, yoga, or mindfulness\n* Regular practice (at least once a week in the last six months) of meditation, yoga, or mindfulness",true,"FEMALE","18 Years",{"count":61,"type":20},88,[23],"The goal of this pilot randomized clinical trial is to evaluate the efficacy of a mindful eating intervention (\"Eat for Life\") on eating behavior, body image, and mental health in female nutrition students. The main questions it aims to answer are: Does a mindful eating intervention reduce disordered eating behaviors in female nutrition students? Does the intervention improve body appreciation, mindfulness levels, and mental health?\n\nResearchers will compare an active control group receiving nutritional guidance to an intervention group participating in the \"Eat for Life\" mindful eating program to see if the mindful eating intervention reduces disordered eating behaviors and improves overall psychological well-being and body appreciation.\n\nParticipants will: Complete online questionnaires evaluating eating behavior, mindfulness, mental health, and body image at three distinct time points: before the intervention (baseline), post-intervention, and at a 3-month follow-up.\n\nIf assigned to the intervention group, attend 12 weekly face-to-face mindful eating sessions lasting approximately two hours each. If assigned to the active control group, receive weekly informative leaflets via WhatsApp with nutritional guidance based on the Dietary Guidelines for the Brazilian Population for 12 weeks",[65,66,67,68,28],"Mental Health","Body Image","Feeding Behavior","Feeding and Eating Disorders",[70,71,72,73],"mindful eating","feeding behavior","Students","mental health","NOT_YET_RECRUITING","2026-05-06",{"date":77,"type":41},"2026-05-11",{"date":79,"type":20},"2026-06-01",{"date":81,"type":20},"2027-12-01",{"name":83,"class":48},"Federal University of Uberlandia",1,{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":91,"eligibilityCriteria":92,"healthyVolunteers":57,"sex":15,"minAge":59,"maxAge":93,"enrollmentInfo":94,"targetDuration":4,"studyType":96,"phases":4,"briefSummary":97,"conditions":98,"keywords":100,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":84},"100629309","heart-rate-variability-in-benign-paroxysmal-positional-vertigo-100629309","NCT07472998","Heart Rate Variability in Benign Paroxysmal Positional Vertigo","Evaluation of Autonomic Function Using Short-Term Heart Rate Variability in Patients With Benign Paroxysmal Positional Vertigo: A Prospective Case-Control Study","BPPV-HRV","Inclusion Criteria:\n\n* BPPV Group\n\nAge 18 years or older\n\nClinical diagnosis of benign paroxysmal positional vertigo (BPPV) confirmed by positional testing (Dix-Hallpike and\u002For Roll test) with positional nystagmus\n\nNo known history of cardiac disease\n\nAbility and willingness to provide written informed consent\n\nHealthy Control Group\n\nAge 18 years or older\n\nNo history of vertigo or known vestibular disorder\n\nAge- and sex-matched to the BPPV group\n\nNo known history of cardiac disease\n\nAbility and willingness to provide written informed consent\n\nExclusion Criteria:\n\n* Age younger than 18 years\n\nInability to provide informed consent or impaired mental capacity\n\nKnown arrhythmia, heart failure, ischemic heart disease, or other clinically significant cardiac disorder\n\nUse of medications that may directly affect heart rate variability, including beta-blockers, non-dihydropyridine calcium channel blockers, antiarrhythmic drugs, digoxin, systemic corticosteroids, centrally acting sympatholytic agents, or psychotropic medications that may influence autonomic balance\n\nActive infection or systemic inflammatory disease","65 Years",{"count":95,"type":20},104,"OBSERVATIONAL","Benign paroxysmal positional vertigo (BPPV) is the most common peripheral vestibular disorder. Although the pathophysiology of BPPV is mainly attributed to the displacement of otoconia within the semicircular canals, recent studies suggest that psychological stress and anxiety may be associated with the onset or recurrence of the disease. However, the biological mechanisms underlying this relationship remain poorly understood, and objective evaluation of autonomic nervous system function in patients with BPPV is limited.\n\nHeart rate variability (HRV) is a non-invasive method widely used to assess autonomic nervous system activity. Short-term HRV measurements provide information about autonomic balance and vagal tone. In particular, parameters such as the root mean square of successive differences (RMSSD) and the coefficient of variation of RR intervals (COV RR\u002FR) are considered indicators of parasympathetic activity.\n\nThe aim of this prospective case-control study is to evaluate vagal tone in patients with BPPV using short-term HRV analysis and to compare the findings with age-, sex-, and body mass index-matched healthy controls. Participants will undergo standardized HRV measurements at rest and during controlled breathing. Perceived stress levels will also be assessed using the Perceived Stress Scale (PSS-10).\n\nThe primary outcomes of the study are RMSSD and the coefficient of variation of RR intervals (COV RR\u002FR), obtained from short-term HRV recordings. These parameters will be compared between BPPV patients and healthy controls, and their associations with perceived stress levels will also be explored. The findings of this study may provide insights into the role of autonomic regulation and stress-related mechanisms in the pathophysiology of BPPV.",[99,28],"BPPV",[99,35,101,102,103],"HRV","heart rate variability","Benign paroxysmal positional vertigo","2026-04-13",{"date":106,"type":41},"2026-04-16",{"date":108,"type":41},"2026-04-01",{"date":110,"type":20},"2026-09-01",{"name":112,"class":48},"Istanbul Aydın University",{"id":114,"slug":115,"hasResults":11,"nctId":116,"briefTitle":117,"officialTitle":118,"acronym":4,"eligibilityCriteria":119,"healthyVolunteers":57,"sex":15,"minAge":59,"maxAge":120,"enrollmentInfo":121,"targetDuration":4,"studyType":21,"phases":123,"briefSummary":124,"conditions":125,"keywords":127,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":132,"lastUpdatePostDateStruct":133,"startDateStruct":135,"completionDateStruct":137,"leadSponsor":139,"locationsCount":84},"100604269","virtual-vs-traditional-cpr-training-effects-on-stress-100604269","NCT07147322","Virtual vs. Traditional CPR Training: Effects on Stress","The Effect of Basic Life Support Training in a Virtual Environment on Perceived Stress and Measured Stress Responses Compared to Conventional Basic Life Support Training","Inclusion Criteria:\n\n* Volunteers (18-30 years old) will be recruited from first- and second-year medical students\n* Participants must be healthy young individuals with no known heart disease, normal physical performance capacity, and no current physical limitations that would affect the ability to perform chest compressions.\n\nExclusion Criteria:\n\n* Pregnant individuals will not be included\n* Individuals with previous healthcare experience will not be included.\n* Participants must not have received basic life support training within the past six months.","30 Years",{"count":122,"type":20},60,[23],"This medical education study investigates stress levels among undergraduate medical students during basic life support (BLS) training. It compares traditional face-to-face teaching session with virtual reality (VR) training simulating a resuscitation scenario in a public place. We will measure heart rate, heart rate variability, and self-reported stress to assess acute stress responses. The study also examines physical sensations related to VR, the realism of the virtual environment, and the suitability of VR for BLS training.",[126,28],"Heart Rate Variability, Biomarker of Stress",[102,128,129,130,131],"perceived mental workload","Virtual reality","Medical education","Basic life support","2025-08-21",{"date":134,"type":41},"2025-08-29",{"date":136,"type":41},"2025-08-13",{"date":138,"type":20},"2026-08-31",{"name":140,"class":48},"Oulu University Hospital"]