[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"stroke-code\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:stroke-code":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100629438","evaluation-of-a-point-of-care-lateral-flow-assay-in-glial-fibrillary-acidic-protein-gfap-and-d-dimer-in-diagnosis-of-large-vessel-occlusion-acute-ischemic-stroke-in-a-pediatric-hospital-100629438",false,"NCT07474675","Evaluation of a Point-of-care Lateral Flow Assay in Glial Fibrillary Acidic Protein (GFAP) and D-dimer in Diagnosis of Large Vessel Occlusion Acute Ischemic Stroke in a Pediatric Hospital","Evaluation of a Point-of-care Lateral Flow Assay in GFAP and D-dimer in Diagnosis of Large Vessel Occlusion Acute Ischemic Stroke in a Pediatric Hospital","Inclusion Criteria:\n\n* Presenting with acute onset (\\\u003C18 hours) spontaneous (no trauma) focal neurologic deficit or altered consciousness\n\nExclusion Criteria:\n\n* Participants with surgery in the past month\n* Participants with known trauma in the past month\n* Participants with known seizure history or anti-seizure medications\n* Participants who are adults with decisional impairment","ALL","0 Years","21 Years",{"count":20,"type":21},250,"ESTIMATED","OBSERVATIONAL","The goal of this study is to test the efficacy of a rapid bedside blood test in determining if a stroke is happening in children who present to the emergency department with stroke symptoms. The main questions it aims to answer are:\n\n* To determine the sensitivity of detecting a large vessel occlusion (LVO) as the etiology of acute ischemic stroke (AIS) in a pediatric population using a point-of-care blood-based assay (LVOne).\n* To determine the positive predictive value (PPV) of LVOne in a pediatric population\n\nParticipants will:\n\n* Provide a small sample of blood to be used to test the accuracy of the device.\n* Participants will still receive all standard of care work-up for stroke, which could include computed tomography\u002Fmagnetic resonance imaging (CT\u002FMRI).",[25,26,27],"Stroke Code","Large Vessel Occlusion","Acute Ischemic Stroke",[29],"Stroke","NOT_YET_RECRUITING","2026-03-12",{"date":33,"type":34},"2026-03-16","ACTUAL",{"date":36,"type":21},"2026-03",{"date":38,"type":21},"2028-07",{"name":40,"class":41},"Boston Children's Hospital","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":54,"conditions":55,"keywords":4,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":42},"100541678","stroke-triage-optimization-by-ambulance-paramedics-in-the-pre-hospital-setting-100541678","NCT06332989","Stroke Triage Optimization by Ambulance Paramedics in the Pre-hospital Setting","Comparison of Prehospital Stroke Screening Scales in the Ambulance Setting; a Multiregional, Multicenter Observational Cohort Study","STROKE-APP","Inclusion Criteria:\n\n* patients for whom a stroke code is activated\n\nExclusion Criteria:\n\n\\\u003C 18 years","18 Years",{"count":53,"type":21},3000,"There are everal scales designed to help ambulance paramedics to identify a patient with a stroke and activate a stroke code. These scales were never tested in the field in a large unselected patient sample. We aim to perform an in-the field head tot head comparison of all published stroke scales designed to be used by ambulance paramedics",[56,57,58,25],"Stroke, Acute","Pre-hospital Triage","Stroke Treatment","RECRUITING","2024-03-20",{"date":62,"type":34},"2024-03-27",{"date":64,"type":34},"2024-02-01",{"date":66,"type":21},"2027-02-01",{"name":68,"class":41},"Leiden University Medical Center"]