[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"stroke-patients\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:stroke-patients":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,14,0,[8,60,94,124,149,176,200,226,251,273,294,325,350,377],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":36,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":48,"lastUpdatePostDateStruct":49,"startDateStruct":52,"completionDateStruct":54,"leadSponsor":56,"locationsCount":59},"100574927","the-effect-of-non-invasive-brain-stimulation-rtms-on-hand-muscles-in-chronic-stroke-patients-100574927",false,"NCT06765642","The Effect of Non-invasive Brain Stimulation rTMS on Hand Muscles in Chronic Stroke Patients.","Evaluation of 3 Patterned rTMS Stimulation Dosage on Corticospinal Excitability and Motor Learning in Stroke Patients","REALISE","Inclusion criteria:\n\n1. Age \\>=21 years old of any race or gender\n2. First-ever ischemic or hemorrhagic stroke (neuroimaging verified) at least 3 months from stroke onset\n3. Unilateral arm weakness measured by FM-UM scale \\\u003C= 62 out of 66\n4. Inducible rest motor threshold and testing motor threshold recorded from the affected first dorsal interosseous (FDI) muscle from the study subject\n\nExclusion criteria\n\n1. Bilateral strokes (infarcts and\u002For hematoma)\n2. Other co-existent neuromuscular disorders affecting upper extremity motor impairment.\n3. History of medically uncontrolled depression or other neuropsychiatric disorders despite medications either before or after a stroke that may affect the subject's ability to participate in the study.\n4. Uncontrolled hypertension despite medical treatment(s) at the time of randomization, defined as SBP≥185 mmHg or DBP≥110 mmHg (patient can be treated, reassessed and randomized later).\n5. Presence of any MRI\u002FrTMS risk factors including but not limited to:\n\n   1. an electrically, magnetically, or mechanically activated metallic or nonmetallic implant including cardiac pacemaker, intracerebral vascular clips or any other electrically sensitive support system.\n   2. a non-fixed metallic part in any part of the body, including a previous metallic injury to the eye.\n   3. history of seizure disorder before stroke or seizure after stroke.\n   4. preexisting scalp lesion or bone defect or hemicraniectomy.\n6. Concurrent enrollment in another interventional stroke recovery study.\n7. Concerns that the subject cannot comply with study procedures and visits.\n8. Pregnant individuals","ALL","21 Years",{"count":20,"type":21},26,"ESTIMATED","INTERVENTIONAL",[24],"NA","The study is about using a brain stimulation technique called rTMS (Repetitive Transcranial Magnetic Stimulation) to help improve hand muscles in people who had a stroke. Researchers want to understand how this device can help stroke patients use their hands better.",[27,28,29,30,31,32,33,34,35],"Stroke","Stroke Patients","Arm Weakness as a Consequence of Stroke","Brain Stimulation","Transcranial Magnetic Stimulation Repetitive","Transcranial Magnetic Stimulation","Motor Learning","Chronic Stroke Patients","Chronic Stroke Survivors",[37,38,39,40,41,42,43,44,45,46],"stroke","arm weakness","arm weakness as a consequence of stroke","stroke patients","transcranial magnetic stimulation","transcranial magnetic stimulation repetitive","motor learning","chronic stroke","chronic stroke patients","chronic stroke survivors","RECRUITING","2026-05-19",{"date":50,"type":51},"2026-05-22","ACTUAL",{"date":53,"type":51},"2025-06-09",{"date":55,"type":21},"2027-04-30",{"name":57,"class":58},"Duke University","OTHER",1,{"id":61,"slug":62,"hasResults":11,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":4,"eligibilityCriteria":65,"healthyVolunteers":11,"sex":17,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":4,"studyType":70,"phases":4,"briefSummary":71,"conditions":72,"keywords":75,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":93},"100594442","young-stroke-service-deep-phenotyping-exploring-recovery-in-young-adult-survivors-of-stroke-100594442","NCT07019493","Young Stroke Service Deep Phenotyping: Exploring Recovery in Young Adult Survivors of Stroke","Inclusion Criteria:\n\n1. Between 18 and 55 years.\n2. Within one month of acute stroke confirmed with standard of care brain imaging or clinical diagnosis or for those for whom recruitment \\\u003C1 month of stroke is not possible they may be recruited to participate within 3-months of stroke\n\nExclusion Criteria:\n\n1. Severe, intercurrent or progressive illness likely to EITHER\n\n   1. Have a prognosis for survival under 24 months; OR\n   2. In the opinion of the investigator will mask the importance to the individual participant data (e.g. severe MS, dementia, etc)\n2. Major psychiatric condition requiring medical intervention","18 Years","55 Years",{"count":69,"type":21},100,"OBSERVATIONAL","The Investigators are running a small, early-phase research study across several hospitals in Melbourne, Australia. The study will involve up to 100 young adults between the ages of 18 and 55 who have had a stroke. The goal is to test how practical it is to carry out a detailed health assessment process-called \"deep phenotyping\"-with this group.\n\nThis process involves collecting a wide range of information and samples from stroke survivors to better understand each participant's condition. The Investigators will look at how well this approach works in practice, including how easy it is to use, whether it's done consistently, and how acceptable it is to participants.\n\nAt the same time, the Investigators will also explore how different factors-such as biological markers (biomarkers), age, sex, type of stroke, lifestyle, and environment-might be related to stroke recovery. This pilot study will prepare for larger studies in the future.",[28,27,73,74],"Stroke; Sequelae","Young Adults",[76,77,78,79,80,81,82,83],"recovery","young stroke","ischemic stroke","hemorrhagic stroke","poststroke fatigue","post-stroke cognitive impairment","function","mood","2026-04-16",{"date":86,"type":51},"2026-04-21",{"date":88,"type":51},"2025-07-19",{"date":90,"type":21},"2027-12",{"name":92,"class":58},"The Florey Institute of Neuroscience and Mental Health",2,{"id":95,"slug":96,"hasResults":11,"nctId":97,"briefTitle":98,"officialTitle":99,"acronym":100,"eligibilityCriteria":101,"healthyVolunteers":11,"sex":17,"minAge":66,"maxAge":4,"enrollmentInfo":102,"targetDuration":4,"studyType":22,"phases":104,"briefSummary":105,"conditions":106,"keywords":109,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":93},"100571630","stroke-and-cpap-outcome-study-3-randomized-controlled-trial-100571630","NCT06722755","Stroke and CPAP Outcome Study 3 Randomized Controlled Trial","Optimizing Adherence to the Treatment of Sleep Apnea Among Patients With Stroke Undergoing Inpatient Rehabilitation","SCOUTS3","Inclusion criteria include:\n\n1. Age 18 years or older\n2. Head CT or brain MRI demonstrating an acute ischemic infarction or intraparenchymal hemorrhage within past 30 days\n3. Person providing consent (patient or legally authorized representative (LAR)) able to be consented in English or Spanish.\n\nExclusion criteria include:\n\n1. Unable to obtain informed consent from participant or LAR in English or Spanish\n2. Incarcerated\n3. Known pregnancy-determined by reviewing clinical data\n4. Current mechanical ventilation, tracheostomy, or supplemental oxygen use \\> 4L\u002Fmin\n5. Use of positive airway pressure within 14 days prior to stroke\n6. History of pneumothorax, bullous emphysema or other serious co-morbid conditions which limit CPAP use\n7. Stroke related to tumors, vascular malformations or subarachnoid hemorrhage\n8. Active use of sedative drugs that can interfere with testing for obstructive sleep apnea (OSA) including any benzodiazepine, barbiturate, general anesthesia, or conscious sedation within the prior 48 hours of the planned portable sleep apnea study\n9. Anticipated inpatient rehabilitation length of stay \\\u003C 5 nights\n10. Co-morbid conditions that limit OSA testing or CPAP use in the judgement of the study team\n11. Recent cranial or spinal surgery with known or possible CSF leak or pneumocephalus within past 3 months\n12. Patients at significant risk of aspiration that could render the patient at risk of harm from use of CPAP, in the opinion of the site PI.",{"count":103,"type":21},250,[24],"The SCOUTS 3 study aims to test the effectiveness of an intensive CPAP (Continuous Positive Airway Pressure) therapy support program compared to usual care in stroke patients with obstructive sleep apnea (OSA) during inpatient rehabilitation (IPR).\n\nThe study is a multicenter randomized controlled trial (RCT) involving recruitment of about 250 participants across two institutions and randomization of about 200 participants. It compares an intensive support (IS) program for CPAP use with standard support (SS) to evaluate the effectiveness of the IS intervention in increasing CPAP usage during and after stroke rehabilitation. The Intensive Support (IS) group will receive a multicomponent intensive behavioral adherence program, which includes a CPAP technical support intervention, Motivational Enhancement Therapy (MET), and a Mobile Health intervention. Outcomes measured include CPAP adherence as measured by average nightly use in minutes between randomization and 3 months and the modified Rankin Scale (mRS-9Q) to evaluate stroke recovery.",[28,107,108],"CPAP","OSA - Obstructive Sleep Apnea",[110,111,112,113,114],"behavioral therapy","continuous positive airway pressure","stroke recovery","self determination","sleep apnea","2026-03-25",{"date":117,"type":51},"2026-03-30",{"date":119,"type":51},"2025-01-15",{"date":121,"type":21},"2028-05",{"name":123,"class":58},"University of Washington",{"id":125,"slug":126,"hasResults":11,"nctId":127,"briefTitle":128,"officialTitle":128,"acronym":4,"eligibilityCriteria":129,"healthyVolunteers":11,"sex":17,"minAge":130,"maxAge":131,"enrollmentInfo":132,"targetDuration":4,"studyType":22,"phases":134,"briefSummary":135,"conditions":136,"keywords":137,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":59},"100535954","effects-of-circuit-training-combining-different-types-of-distal-robot-assisted-and-task-oriented-therapy-on-motor-control-motor-and-daily-functions-and-quality-of-life-after-stroke-100535954","NCT06258538","Effects of Circuit Training Combining Different Types of Distal Robot-assisted and Task-oriented Therapy on Motor Control, Motor and Daily Functions, and Quality of Life After Stroke","Inclusion Criteria:\n\n1. unilateral stroke ≥ 3 months onset\n2. Fugl-Meyer Assessment for Upper Extremity (FMA-UE) score between 18 to 56, indicating different levels of motor impairments ;\n3. without excessive spasticity in any of the UE joint (modified Ashworth scale ≤3 in proximal joints and modified Ashworth scale ≤2 in distal joints);\n4. Mini Mental State Exam (MMSE) score \\> 24, indicating no serious cognitive impairment;\n5. between the ages of 20 and 75 years -\n\nExclusion Criteria:\n\n1. histories of other neurological diseases such as dementia, Parkinson's disease, and peripheral polyneuropathy;\n2. difficulties in following and understanding instructions such as global aphasia;\n3. enroll in other rehabilitation or drug studies simultaneously;\n4. receiving Botulinum toxin injections within 3 months. -","20 Years","75 Years",{"count":133,"type":21},87,[24],"This study proposes a novel stroke rehabilitation approach for upper extremity training by firstly combining different types of distal robot-assisted and task-oriented therapy in a circuit training program. The program could enhance UE functions, improving daily function, decrease caregiver burden and lower medical expenses associated with long-term care. Professionals can use these findings to promote the application of clinically empirical research and better understand the effects and mechanisms of circuit training.",[28],[138,139],"Stroke rehabilitation","distal upper extremity","2026-03-18",{"date":142,"type":51},"2026-03-20",{"date":144,"type":51},"2024-06-01",{"date":146,"type":21},"2026-12-31",{"name":148,"class":58},"Chang Gung Memorial Hospital",{"id":150,"slug":151,"hasResults":11,"nctId":152,"briefTitle":153,"officialTitle":154,"acronym":4,"eligibilityCriteria":155,"healthyVolunteers":11,"sex":17,"minAge":156,"maxAge":131,"enrollmentInfo":157,"targetDuration":4,"studyType":22,"phases":159,"briefSummary":160,"conditions":161,"keywords":163,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":167,"lastUpdatePostDateStruct":168,"startDateStruct":170,"completionDateStruct":172,"leadSponsor":174,"locationsCount":59},"100583619","individualized-exercise-prescription-with-a-data-driven-approach-in-individuals-with-stroke-100583619","NCT06878677","Individualized Exercise Prescription With a Data-driven Approach in Individuals With Stroke","Individualized Exercise Prescription With a Data-driven Approach in Individuals With Stroke - A Feasible Study","Inclusion Criteria:\n\n* between 45 and 75 years old;\n* have received a diagnosis of stroke more than six months earlier;\n* able to walk 10 m independently;\n* able to score at least 6 of 10 on the Abbreviated Mental Test;\n* able to follow instructions and give informed consent.\n\nExclusion Criteria:\n\n* any existing medical condition such as uncontrolled hypertension that hindered training or assessment;\n* unable to offer consent due to impaired cognitive function.","45 Years",{"count":158,"type":21},52,[24],"The goal of this clinical trial is to evaluate if the exercised via data-driven approach is effective in enhance the gait pattern in people with stroke. It will reduce burdun of patient consultations for clinicians in reality.The main questions it aims to answer are:\n\nDoes individualized exercise training programmes via data-driven approach could improve gait patterns in individuals with chronic stroke? Does individualized exercise training programmes via data-driven approach could improve improve motor recovery, motor functions (including gait speed and balance performance), and community integration in individuals with chronic stroke?\n\nParticipants will:\n\nUndergo 12 supervised-exercise (training sessions (60 minutes, two times a week, for six weeks), Participants will receive a data-driven exercise prescription or conventional exercise prescription which consists of 5 different exercises.\n\nThey will be assessed on Baseline assessment before training (A0); after six sessions (A1); after 12 sessions (A2); and three months after training (A3).",[162,28,27],"Stroke Gait Rehabilitation",[37,164,165,166],"lower extremities","gait","rehabilitation","2025-09-08",{"date":169,"type":51},"2025-09-15",{"date":171,"type":51},"2024-07-01",{"date":173,"type":21},"2026-10-31",{"name":175,"class":58},"The Hong Kong Polytechnic University",{"id":177,"slug":178,"hasResults":11,"nctId":179,"briefTitle":180,"officialTitle":181,"acronym":4,"eligibilityCriteria":182,"healthyVolunteers":11,"sex":17,"minAge":66,"maxAge":4,"enrollmentInfo":183,"targetDuration":4,"studyType":22,"phases":185,"briefSummary":186,"conditions":187,"keywords":4,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":190,"lastUpdatePostDateStruct":191,"startDateStruct":193,"completionDateStruct":195,"leadSponsor":197,"locationsCount":199},"100569318","afo-prescription-to-optimize-post-stroke-function-100569318","NCT06692686","AFO Prescription to Optimize Post-Stroke Function","The Development of Patient-Centered Clinical AFO Prescription Guidelines to Optimize Post-Stroke Function and Quality of Life","Inclusion Criteria:\n\n* be a minimum of three months post-stroke\n* be greater than 18 years of age\n* have been prescribed either a semi-rigid or a custom-made articulating AFO\n* wear their prescribed AFO for all primary mobility activity outside the house\n* be able to walk at least 20 meters without manual assistance\n* walk at least 10 meters per minute (12% of normal velocity) during a 6-meter self-selected velocity walking test.\n\nExclusion Criteria:\n\n* having a condition that could significantly limit ambulation, including severe osteoarthritis, rheumatoid arthritis, congestive heart failure, or pre-existing neurological disorder other than post-stroke\n* having cognitive deficits that preclude their ability to provide consent for participation\n* having an ankle plantar flexion contracture equal to or greater than 15 degrees plantar flexion with full knee extension",{"count":184,"type":21},120,[24],"The overall goal of this study is to attain the highest possible health-related quality of life for individuals with lower-limb impairment through a clinical trial examining three different modern carbon fiber ankle-foot orthosis (AFO) treatment options targeting the rehabilitation of individuals post-stroke. To achieve this goal, the investigators will:\n\n1. Identify the factors that significantly contribute to an individual's highest potential quality of life when considering each of the three available AFO design options, and\n2. Develop prediction models of clinical performance using biomechanical function linked to the three AFO designs.\n\nParticipants will be asked to:\n\n* Wear each of the three modern AFO designs for one month, after receiving therapy training and\n* Complete questionnaires and performance tests with each AFO.\n\nIn addition, the subset of individuals participating in goal 2) will also be asked to:\n\n* Perform biomechanical analyses using high-speed cameras and force plates during different walking and balance tests with each AFO design.",[188,28,189],"Ankle Foot Orthosis (AFO)","Post-Stroke Hemiparesis","2025-08-15",{"date":192,"type":51},"2025-08-21",{"date":194,"type":51},"2025-07-08",{"date":196,"type":21},"2027-10",{"name":198,"class":58},"University of Texas at Austin",4,{"id":201,"slug":202,"hasResults":11,"nctId":203,"briefTitle":204,"officialTitle":204,"acronym":205,"eligibilityCriteria":206,"healthyVolunteers":11,"sex":17,"minAge":66,"maxAge":207,"enrollmentInfo":208,"targetDuration":4,"studyType":70,"phases":4,"briefSummary":210,"conditions":211,"keywords":212,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":217,"lastUpdatePostDateStruct":218,"startDateStruct":220,"completionDateStruct":222,"leadSponsor":224,"locationsCount":59},"100578926","predicting-language-recovery-in-acute-stroke-patients-in-the-neurovascular-intensive-care-unit-an-exploratory-study-with-the-core-assessment-of-language-processing-100578926","NCT06817642","Predicting Language Recovery in Acute Stroke Patients in the Neurovascular Intensive Care Unit: An Exploratory Study With the Core Assessment of Language Processing.","PREDICT-CALAP","Inclusion Criteria:\n\n* Age: between 18 and 85 years old\n* Inpatient in the initial phase of stroke (between 0 and 21 days after stroke)\n* Hemispheric stroke, ischemic or haemorrhagic\n* Ability to participate in tests\n* Francophone\n* 4≤ NIHSS score ≤21 or if NIHSS score \\\u003C 4, LAST score \\[0-13\\]\n* Non-opposition to participation in tests\n\nExclusion Criteria:\n\n* Severe alertness impairment incompatible with test participation, NIHSS score 1a. different from 0\n* Severe overall intellectual deterioration incompatible with test participation\n* Patients who may have a visual or hearing impairment incompatible with participation in CALAP\n* History of stroke\n* Posterior fossa stroke","85 Years",{"count":209,"type":21},570,"Introduction:\n\nStroke affects one person every 4 minutes in France (i.e. more than 140,000 new cases per year) resulting in cognitive and motor disorders. Aphasia is one of the most devastating cognitive disorders that persist in the late phase. However, early treatment of aphasia can improve the effects of rehabilitation.\n\nIdentifying, as early as possible, the patients most at risk of presenting persistent language disorders in the late phase would make it possible to improve their management and increase the effects of cognitive rehabilitation on their language abilities.\n\nThe aim of this project is to evaluate whether the Core Assessment of Language Processing (CALAP) assessed in the acute phase of stroke can predict language abilities in the late phase.\n\nHypothesis\u002FObjective:\n\nThe primary objective is to determine whether the language abilities of patients in the acute phase of stroke can be used to predict language abilities in the late phase. Secondary objectives are to determine whether prediction can be improved with (1) brain MRI data and (2) neuropsychological assessment data. The (3) secondary objective is to determine whether cognitive abilities at the chronic phase can be predicted by language performance in the acute phase. The (4) secondary objective is to assess whether language rehabilitation modifies the predictive power of the language abilities assessed with the CALAP.\n\nMethod:\n\nPatients will be included during their hospitalization after a brain vascular injury (acute phase, up to 21 days of hospitalization). After discharge, they will return for a post-stroke assessment between 3 and 18 months after the acute phase.\n\nDuring these two visits, a clinical and neurological examination, a neuropsychological assessment and an MRI will be performed.\n\nA prediction model (development and validation) will be used for all objectives using a linear regression model with cross validation. The entire sample consists of stroke patients.\n\nThe study is single-center and will have a total duration of 6 years with an estimated 570 patients included.\n\nConclusion:\n\nPredicting the language abilities of a post-stroke patient will improve clinical management and direct patients requiring language rehabilitation to appropriate care.",[28],[27,213,214,215,216],"Aphasia","Language abilities","Cognitive abilities","Prediction of function recovery","2025-05-30",{"date":219,"type":51},"2025-06-04",{"date":221,"type":51},"2023-01-01",{"date":223,"type":21},"2029-12-01",{"name":225,"class":58},"Assistance Publique - Hôpitaux de Paris",{"id":227,"slug":228,"hasResults":11,"nctId":229,"briefTitle":230,"officialTitle":231,"acronym":4,"eligibilityCriteria":232,"healthyVolunteers":233,"sex":17,"minAge":66,"maxAge":4,"enrollmentInfo":234,"targetDuration":4,"studyType":70,"phases":4,"briefSummary":236,"conditions":237,"keywords":238,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":242,"lastUpdatePostDateStruct":243,"startDateStruct":245,"completionDateStruct":247,"leadSponsor":249,"locationsCount":59},"100536057","relationship-between-respiratory-muscle-strength-balance-trunk-control-functional-capacity-in-stroke-patients-100536057","NCT06259877","Relationship Between Respiratory Muscle Strength, Balance, Trunk Control, Functional Capacity in Stroke Patients","Determination of the Relationship Between Respiratory Muscle Strength, Respiratory Functions, Balance, Trunk Control, Functional Capacity and Motor Functions in Stroke Patients and Comparison With Healthy Individuals","Inclusion Criteria:\n\n* Stroke individuals over the age of 18\n\nExclusion Criteria:\n\n* Patients with another neurological problem (Parkinson, Multiple sclerosis, etc.) that will affect functionality and balance other than stroke\n* Patients with orthopedic problems (short limbs, spine and lower extremity surgery) with pulmonary disease\n* Patients with cooperation and communication problems",true,{"count":235,"type":21},44,"The purpose of this study; To determine the relationship between respiratory muscle strength, balance, trunk control, functional capacity and motor functions in stroke patients and compare them with healthy individuals.",[28],[239,240,241],"Respiratory Function","Postural Control","Balance","2025-04-27",{"date":244,"type":51},"2025-04-30",{"date":246,"type":51},"2021-03-01",{"date":248,"type":21},"2025-07-01",{"name":250,"class":58},"Kırıkkale University",{"id":252,"slug":253,"hasResults":11,"nctId":254,"briefTitle":255,"officialTitle":255,"acronym":4,"eligibilityCriteria":256,"healthyVolunteers":11,"sex":17,"minAge":156,"maxAge":4,"enrollmentInfo":257,"targetDuration":4,"studyType":22,"phases":259,"briefSummary":260,"conditions":261,"keywords":262,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":265,"lastUpdatePostDateStruct":266,"startDateStruct":268,"completionDateStruct":270,"leadSponsor":271,"locationsCount":59},"100588731","task-oriented-mirror-therapy-for-upper-limb-motor-function-in-stroke-patient-100588731","NCT06945211","Task Oriented Mirror Therapy for Upper Limb Motor Function in Stroke Patient","Inclusion Criteria:\n\n* Both genders.\n* Age of patient 45 years and above\n* Both ischemic and hemorrhagic stroke ( subacute and chronic stroke). Cognitive function relatively intact score \\> 24 MoCA\n* The patient can sit with \u002F without support for more than 30 min\n\nExclusion Criteria:\n\n* Subjects with visual impairments or unilateral neglect.\n* having global aphasia.\n* unstable medical conditions or comorbidities.\n* score 3 and above on modified ashworth scale.\n* patient with orthopedic condition or any fractures.",{"count":258,"type":21},36,[24],"Stroke remains a major public health disease worldwide ,it usually associating with damage to the motor function and other functional disabilities. Persistent upper extremity dysfunction affects many post strokepatients and is strongly associated with decreased activities of daily living . Mirror therapy one of the rehabilitation that is beneficial for neuroplasticity .This therapy is used to improve motor function after stroke .",[28],[263,27,264],"Mirror Therapy","Neurorehabilitation","2025-04-18",{"date":267,"type":51},"2025-04-25",{"date":269,"type":51},"2024-09-10",{"date":217,"type":21},{"name":272,"class":58},"Foundation University Islamabad",{"id":274,"slug":275,"hasResults":11,"nctId":276,"briefTitle":277,"officialTitle":278,"acronym":4,"eligibilityCriteria":279,"healthyVolunteers":11,"sex":17,"minAge":66,"maxAge":4,"enrollmentInfo":280,"targetDuration":282,"studyType":70,"phases":4,"briefSummary":283,"conditions":284,"keywords":4,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":285,"lastUpdatePostDateStruct":286,"startDateStruct":288,"completionDateStruct":290,"leadSponsor":292,"locationsCount":59},"100582464","short-term-effect-of-using-non-immersive-gamified-exercises-on-chronic-pain-in-people-with-stroke-100582464","NCT06863649","Short-term Effect of Using Non-immersive Gamified Exercises on Chronic Pain in People With Stroke.","Measuring Biomarkers for Health in Community Environments: eMBraCE Activity Program; Short Term Effect of Using Non-immersive Gamified Exercises on Chronic Shoulder Pain in People With Chronic Stroke.","Inclusion Criteria:\n\n* Experiencing motor difficulties in using the paretic arm, with some use of hand\u002Farm as determined by therapist\n* Not participating any other intervention studies\n* Male\u002Ffemale ≥18 years old\n* Had a stroke requiring with any degree of arm mobility.\n* Capacity to consent to participate\n* Able to communicate adequately in English with the research team\n* Mild or moderate pain in shoulder or upper limb (below 6 and more than 2on the VAS scale).\n* Able to walk without any assistant at least for ten meters\n\nExclusion Criteria:\n\n* Any medical condition compromising the safety or the ability to take part to the study as determined by the therapist (such as insufficient vision or hearing, upper limb condition not linked to stroke, uncontrolled blood pressure, uncontrolled diabetes, co-morbidity)\n* History of more than one epileptic seizures since stroke onset or uncontrolled epileptic seizure\n* Unable to follow two stage command\n* Moderate to severe hemi-spatial neglect compromising the ability to take part to the study, as determined by rehab team\n* Severe spasticity (more than 2 on the modified Ashworth scale)\n* Any device preventing use of EMG, FNIRS i.e. DBS or pacemaker",{"count":281,"type":21},30,"1 Day","Rehabilitation after stroke is essential to minimize permanent disability. Gamification of exercises has emerged as a promising strategy for increasing motivation and rehabilitation efficacy in people with stroke. However, there is a gap in understanding how exercise gamification can aid in pain management among people with stroke who are experiencing shoulder pain difficulties.\n\nThis study aims to evaluate the short-term effect of using gamified non-immersive exercises on shoulder pain level, upper limb range of motion, and shoulder and elbow muscle activities while doing different activities in people with chronic stroke. The study will be conducted using an observational study design. Various lab assessments include measuring the ROM of the shoulder (MOCAP), EMG, FNIRS, pain intensity using VAS scale, and muscles activities patterns across upper limb joints.",[28],"2025-04-15",{"date":287,"type":51},"2025-04-16",{"date":289,"type":51},"2025-03-01",{"date":291,"type":21},"2025-09",{"name":293,"class":58},"University of Exeter",{"id":295,"slug":296,"hasResults":11,"nctId":297,"briefTitle":298,"officialTitle":299,"acronym":300,"eligibilityCriteria":301,"healthyVolunteers":11,"sex":17,"minAge":302,"maxAge":4,"enrollmentInfo":303,"targetDuration":4,"studyType":22,"phases":305,"briefSummary":306,"conditions":307,"keywords":308,"overallStatus":315,"whyStopped":4,"lastUpdateSubmitDate":316,"lastUpdatePostDateStruct":317,"startDateStruct":319,"completionDateStruct":321,"leadSponsor":323,"locationsCount":4},"100583096","feasibility-of-a-physiotherapy-programme-with-integrated-telerehabilitation-to-increase-rehabilitation-time-and-improve-motor-function-100583096","NCT06871878","Feasibility of a Physiotherapy Programme, with Integrated TelerehabIlitation to Increase Rehabilitation Time and Improve Motor Function","PeRsonAlised Community Based TelerehabIlitation Post StrokE to Increase Rehabilitation Time and Improve Motor Recovery: a Feasibility Study","PRACTISE","1. Individuals who have experienced a stroke.\n\n   Inclusion criteria:\n   * Over 16 years old\n   * Within two months of first stroke\n   * Requiring community physiotherapy and discharged home from in-patient care\n   * Scores 2-4 on the modified Rankin Score on discharge\n   * Able to use a computer\u002Ftablet or mobile phone with\u002Fwithout help from carers' (participants who lack digital connectivity skills\u002F Products will be assisted through AbilityNet)\n   * Able to understand\u002Fcommunicate in English\n   * Capacity to provide informed consent\n\n   Exclusion criteria:\n   * Participating in another physical interventional research study\n   * Discharged to a nursing home or other long-term care facility\n   * Absolute contra-indication to exercise\n2. Carers or family members of individuals who have experienced a stroke.\n\n   Inclusion criteria:\n   * Significant other\u002Fcarer of an individual who is part of the PRACTISE study either as a control participant or as an intervention participant\n   * Over the age of 16 years\n   * Able to join and contribute to an interview, either in-person or via a video conference platform, in English.\n3. Treating physiotherapist who will deliver the PRACTISE intervention.\n\nInclusion criteria:\n\n* UK-based Physiotherapist who has delivered the PRACTISE intervention\n* Able to join and contribute to an interview via video conference platform or in person\n* Over the age of 18 years","16 Years",{"count":304,"type":21},60,[24],"About two thirds of people after stroke have some level of disability. Rehabilitation helps to reduce disability and supports people to return to a meaningful life. We know that the more rehabilitation you do especially, within the first six months after stroke, the better the outcome. However, rehabilitation services, especially in the community, are often lacking, non-specialist or provide only a limited number of therapy sessions. Recently national guidelines for care of people after stroke recommend that people receive up to three hours\u002Fday of therapy on at least five days\u002Fweek. NHS services cannot provide this level of therapy so new ways to support people to increase the amount of therapy they do on their own is needed.\n\nThe aim of the research is to test a 16 week community, home-based physiotherapy programme to improve the amount of therapy exercise a stroke survivor does, therefore improving the outcome and reducing the level of disability.\n\nParticipants will be recruited as they transition from inpatient services to community physiotherapy. Participants will be randomised to either the control or intervention arm. Participants in the intervention arm will take part in a 16-week community, home-based physiotherapy programme. Within the 16-week intervention, participants will receive 5 home based and 4 remote appointments which will comprise of usual physiotherapy assessment and exercise prescription that incorporates 1) Personalised online exercise programme delivered through the Giraffe platform; 2) Goal setting and Action Planning (G-AP); and 3) Supported self-management approaches. Participants will receive an intervention workbook to support them with strategies to achieve their goals and build their self-management skills e.g. how to integrate therapy into their daily life, dealing with barriers, identifying social support networks.\n\nParticipants randomised to the control group will receive usual multi-disciplinary rehabilitation from their care team (e.g., physiotherapist, Occupational Therapists, Speech and Language Therapists) as per their NHS Health boards care plan.\n\nThe study will measure both feasibility outcomes associated with the implementing the study alongside clinical and wellbeing measures.\n\nTo test the feasibility of the study we will assess how many people agree to take part, complete the exercise sessions and complete the outcome measurements. We will also interview people affected by stroke, their significant others if appropriate, and therapists to get their views on the programme. We will do clinical assessments too at four time points across the study looking at walking ability, arm function, level of disability, confidence level, fatigue and quality of life.",[28,27],[27,309,310,311,312,313,314],"Physiotherapy","Exercise","TelerehabIlitation","Feasibility","Goal-Setting","Self-managment","NOT_YET_RECRUITING","2025-03-17",{"date":318,"type":51},"2025-03-19",{"date":320,"type":21},"2025-05",{"date":322,"type":21},"2027-02",{"name":324,"class":58},"Glasgow Caledonian University",{"id":326,"slug":327,"hasResults":11,"nctId":328,"briefTitle":329,"officialTitle":330,"acronym":331,"eligibilityCriteria":332,"healthyVolunteers":233,"sex":17,"minAge":66,"maxAge":333,"enrollmentInfo":334,"targetDuration":4,"studyType":70,"phases":4,"briefSummary":336,"conditions":337,"keywords":338,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":341,"lastUpdatePostDateStruct":342,"startDateStruct":344,"completionDateStruct":346,"leadSponsor":348,"locationsCount":59},"100569609","feasibility-and-reliability-of-using-becuretm-virtual-reality-in-patients-with-stroke-100569609","NCT06696469","Feasibility and Reliability of Using BeCureTM Virtual Reality in Patients With Stroke","Feasibility and Reliability of Using BeCureTM Virtual Reality in the Evaluation of Upper Extremity Motor Functions in Patients With Stroke","cros-sectional","Inclusion Criteria:\n\n1. Patients diagnosed with stroke according to the World Health Organization with an age range of 18-80 years\n2. Patients with subacute to chronic stroke\n3. Patients who can understand commands\n4. Patients with sitting balance\n5. Patients with a first stroke attack\n6. Patients who have never received virtual reality therapy\n7. Upper extremity Brunnstrom Stage III and above\n8. Patients with a spasticity level below 3 according to the Modified Ashworth Scale (MAS) in the affected upper extremity (MAS 1-5 rating system)\n9. Patients who agreed to participate in the study and signed the informed consent form\n\nExclusion Criteria:\n\n1. History of seizures or epilepsy (except childhood febrile seizures),\n2. Arthritis or pain in the affected upper limb that limits repetitive exercise,\n3. Severe aphasia, cognitive impairment (premorbid dementia) or psychiatric disorders,\n4. Spasticity in the affected arm is 3 or more compared to MAS,\n5. Patients without sitting balance,\n6. Patients with posterior cerebral artery infarction,\n7. Patients with subarachnoid hemorrhage,\n8. Patients with visual impairments that may affect the virtual reality application","80 Years",{"count":335,"type":21},34,"The aim of this study is to demonstrate the feasibility and reliability of using virtual reality-based BeCureTM in the assessment of upper extremity motor functions in stroke patients.It is necessary to define the appropriate patient profile for the evaluation of upper extremity motor functions in stroke patients with virtual reality method. We aimed to examine the effects of demographic characteristics, accompanying cognitive disorders and upper extremity motor disorders that may affect the evaluation and response to treatment on virtual reality applications. Therefore, BeCure TM virtual reality system can be feasibly used in the evaluation and rehabilitation of stroke patients.",[28],[339,37,340],"upper limb motor functions","virtual reality","2024-11-20",{"date":343,"type":51},"2024-11-22",{"date":345,"type":51},"2024-06-22",{"date":347,"type":21},"2026-06-22",{"name":349,"class":58},"Ankara University",{"id":351,"slug":352,"hasResults":11,"nctId":353,"briefTitle":354,"officialTitle":355,"acronym":4,"eligibilityCriteria":356,"healthyVolunteers":11,"sex":17,"minAge":357,"maxAge":358,"enrollmentInfo":359,"targetDuration":4,"studyType":22,"phases":361,"briefSummary":362,"conditions":363,"keywords":364,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":368,"lastUpdatePostDateStruct":369,"startDateStruct":371,"completionDateStruct":373,"leadSponsor":375,"locationsCount":59},"100567867","effects-of-vestibular-rehabilitation-on-balance-and-post-stroke-fatigue--100567867","NCT06673771","Effects of Vestibular Rehabilitation on Balance and Post Stroke Fatigue :","Effects of Vestibular Rehabilitation on Balance and Post Stroke Fatigue: a Randomized Control Trial","Inclusion Criteria:\n\n* Patient diagnosed with stroke.\n* Ability to stand for at least 1 minute without support.\n* Fatigue Assessment Scale (FAS) score ≥ 24.\n* Willingness to participate\n\nExclusion Criteria :\n\n* Cognitive Impairment.\n* Severe unilateral spatial neglect.\n* Severe aphasia.\n* Patients who are not willing.","30 Years","65 Years",{"count":360,"type":21},56,[24],"The objective of the study is to determine the effects of stroke conventional therapy compared with the effects of vestibular rehabilitation therapy on balance and post stroke fatigue. The study will be randomized control trial including 2 experimental groups with estimated 28 individual in each group",[28],[365,366,367],"conventional treatment","VRT Treatment","stroke population","2024-11-04",{"date":370,"type":51},"2024-11-05",{"date":372,"type":51},"2024-11-01",{"date":374,"type":21},"2025-03-21",{"name":376,"class":58},"Riphah International University",{"id":378,"slug":379,"hasResults":11,"nctId":380,"briefTitle":381,"officialTitle":381,"acronym":382,"eligibilityCriteria":383,"healthyVolunteers":11,"sex":17,"minAge":66,"maxAge":4,"enrollmentInfo":384,"targetDuration":386,"studyType":70,"phases":4,"briefSummary":387,"conditions":388,"keywords":391,"overallStatus":315,"whyStopped":4,"lastUpdateSubmitDate":395,"lastUpdatePostDateStruct":396,"startDateStruct":398,"completionDateStruct":400,"leadSponsor":402,"locationsCount":59},"100566925","acquired-brain-injury-and-neurorehabilitation-the-influence-of-psychological-characteristics-100566925","NCT06661512","Acquired Brain Injury and Neurorehabilitation: the Influence of Psychological Characteristics","DANEA","Inclusion Criteria:\n\n1. Age over 18 years\n2. Present acquired brain damage (stroke, head trauma, encephalopathy, brain tumor, or anoxia) after less than 6 months of evolution.\n3. Participants must present a cognitive alteration objectified through a neuropsychological examination.\n4. Be correctly oriented in person, space and time (assessed by psychometric tests).\n5. Have a good command of Spanish.\n\n   Exclusion Criteria:\n6. Presenting a neurological or psychiatric history.\n7. Presenting a language disorder or severe visual-perceptive disorder - hemineglect - that prevents participation in the study (does not allow for correct administration of the questionnaire).\n8. A posteriori criterion (once the study has begun): Answering incorrectly to any of the validity items included in the questionnaire. This situation leads to automatic exclusion from studies.\n\nThe initial neuropsychological examination will be used to check whether participants meet inclusion criteria 3 and 4, as well as exclusion criterion 7. This examination includes orientation tests (subtest of the Barcelona Orientation Test), language tests (subtests of the Barcelona Word Repetition Test, Word Naming and Command Comprehension Test) and visual-perception tests (subtests of the Barcelona Superimposed Figures Test). Only those participants who correctly answer all the items will be selected.",{"count":385,"type":21},200,"4 Months","Acquired brain damage generates motor, cognitive, behavioral and emotional deficits. Neurorehabilitation aims to reduce these deficits and develop compensatory strategies that increase the person's functionality. However, the success of neurorehabilitation process varies and is influenced by the type of injury, the characteristics of the patient or the treatment received. Despite all the studies about patient characteristics, psychological aspects currently continue to be a field to be explored.\n\nThe main objective of the study is to study the psychological characteristics of people with brain damage. Secondary objectives include analyzing its link with other indicators, exploring possible differences depending on the etiology of brain damage, assessing its evolution during neurorehabilitation and exploring its prognostic value.\n\nTo carry out this prospective longitudinal observational study, adult patients with acquired brain damage to less than 6 months of evolution who present an objective cognitive alteration will be selected. Patients with a neurological or psychiatric history will be excluded.\n\nPatients included in the study will be administered computerized questionnaires at the beginning of the neurorehabilitation program. The same questionnaires will be administered again 2 months later. In those hospitalized patients who subsequently continue outpatient treatment, a third administration will be performed (2 months after the second administration).",[389,28,390],"Brain Injury","TBI-Traumatic Brain Injury",[392,393,394],"brain injury","neurorehabilitation","psychological characteristics","2024-10-25",{"date":397,"type":51},"2024-10-28",{"date":399,"type":21},"2024-11",{"date":401,"type":21},"2029-11",{"name":403,"class":58},"Institut Guttmann"]