[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"stroke-rehabilitaion\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:stroke-rehabilitaion":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,49,72],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100634990","comparative-effects-of-mirror-therapy-and-cognitive-orientation-to-daily-occupational-performance-in-stroke-a-randomized-controlled-trial-100634990",false,"NCT07546864","Comparative Effects of Mirror Therapy and Cognitive Orientation to Daily Occupational Performance in Stroke: A Randomized Controlled Trial","Comparative Effects of Mirror Therapy, Cognitive Orientation to Daily Occupational Performance, and Conventional Occupational Therapy in Individuals With Stroke: A 3-Month Follow-Up Randomized Controlled Trial","Inclusion Criteria:\n\n* \\- Individuals diagnosed with ischemic or hemorrhagic stroke\n* Age 18 years and older\n* Subacute (3-6 months post-stroke) or chronic stage (6-12 months post-stroke)\n* Brunnstrom Motor Recovery Stage ≥3 for upper extremity, ≥4 for hand, and ≥4 for lower extremity\n* Mini-Mental State Examination (MMSE) score ≥24\n* No severe visual, orthopedic, or additional neurological impairments\n* Not participating in another study during the research period\n* Voluntary consent to participate in the study\n\nExclusion Criteria:\n\n* \\- Poor motor coordination or major medical problems that would prevent participation\n* Presence of Wernicke's aphasia\n* Botulinum toxin injection within the last 3 months\n* Psychiatric conditions that may interfere with participation (e.g., depression, ongoing psychiatric treatment, low motivation)","ALL","18 Years",{"count":19,"type":20},45,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study aims to compare the effectiveness of three rehabilitation approaches in individuals with stroke: mirror therapy (MT), cognitive orientation to daily occupational performance (CO-OP), and conventional occupational therapy (COT), all combined with robotic balance training.\n\nA total of 45 individuals with subacute and chronic stroke will be randomly assigned to one of three groups. Each group will receive 4 weeks of intervention (5 sessions per week), followed by a 3-month follow-up period.\n\nOutcomes related to motor function, somatosensory function, activities of daily living, participation, and quality of life will be assessed at baseline, after intervention, and at follow-up.\n\nThe study aims to determine which intervention approach is more effective in improving functional outcomes in individuals with stroke.",[26,27],"Stroke","Stroke Rehabilitaion",[29,30,26,31,32,33,34,35],"mirror therapy","Randomized Controlled Trial","Cognitive Orientation to Daily Occupational Performance Occupational Therapy","somatosensory","participation","activity daily of life","occupational therapy","RECRUITING","2026-04-17",{"date":39,"type":40},"2026-04-23","ACTUAL",{"date":42,"type":40},"2026-02-15",{"date":44,"type":20},"2027-06-15",{"name":46,"class":47},"Hacettepe University","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":21,"phases":58,"briefSummary":60,"conditions":61,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":48},"100502003","phase-2-transcranial-direct-current-stimulation-for-post-stroke-fatigue-100502003","NCT05816603","Transcranial Direct Current Stimulation for Post-stroke Fatigue","Home-based Post-stroke Fatigue Treatment Using Transcranial Direct Current Stimulation (tDCS)","Inclusion Criteria:\n\n* Male or female patients aged \\>18 years\n* Greater than 3 months from first hemorrhagic or ischemic stroke (subacute to chronic), confirmed through neuroimaging (CT or MRI).\n* Fatigue severity score average \\>4 (severe fatigue)\n* Willingness to remain stable on pharmacologic therapy through the duration of the study.\n* Availability of a caregiver, family member, or friend to be present during the administration of the tDCS intervention.\n\nExclusion Criteria:\n\n* Metal in the head (except mouth) or implanted cranial or thoracic devices (i.e. pacemaker, DBS stimulator)\n* History of seizure\n* History of moderate to severe traumatic brain injury\n* A score of 10 or more on the PHQ-9 or GAD-7 scale, suggestive of moderate to severe depression\u002Fanxiety.\n* A score of less than 21 on the MoCA suggesting major neurocognitive disorder.\n* Signs of skin rash, infection, or laceration in the supraorbital region where the tDCS will be applied.\n* Inability to provide informed consent\n* Other major neurological, medical, or psychiatric illnesses that could confound results in the opinion of the site investigator.",{"count":57,"type":20},24,[59],"PHASE2","The investigators hypothesize that delivery of anodal tDCS to the left frontal head region will reduce fatigue severity following stroke.",[62,27],"Fatigue","2026-02-24",{"date":65,"type":40},"2026-02-27",{"date":67,"type":40},"2023-05-23",{"date":69,"type":20},"2027-12",{"name":71,"class":47},"Weill Medical College of Cornell University",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":80,"targetDuration":4,"studyType":21,"phases":82,"briefSummary":84,"conditions":85,"keywords":86,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":98},"100574862","phase-3-investigating-the-efficacy-of-combining-virtual-reality-based-mirror-therapy-vrmt-and-transcranial-direct-current-stimulation-tdcs-to-improve-upper-limb-recovery-in-patients-with-stroke-100574862","NCT06764797","Investigating the Efficacy of Combining Virtual Reality-Based Mirror Therapy (VRMT) and Transcranial Direct Current Stimulation (tDCS) to Improve Upper Limb Recovery in Patients with Stroke","Investigating the Efficacy of Combining Virtual Reality-Based Mirror Therapy and Transcranial Direct Current Stimulation to Improve Upper Limb Recovery in Patients with Stroke","tDCS","Inclusion Criteria:\n\n* At least 18 years old.\n* Stroke patients with unilateral cerebral infarction or hemorrhage, more than three months following the stroke.\n* Adequate cognitive ability to follow instructions (The Arabic version of the Mini-Mental State Examination scores \\> 24).\n* Modified Ashworth scale score \\\u003C 3.\n* Fugl-Meyer Assessment (FMA) score of 10-58 indicating moderate-to-severe arm impairment.\n\nExclusion Criteria:\n\n* visual impairment and field defect or hemi-sensory inattention and unilateral neglect.\n* Wernicke's aphasia, or global aphasia, leads to difficulty following instructions.\n* Any contraindication to NIBS.\n* Other neurological conditions or participation in another study.",{"count":81,"type":20},300,[83],"PHASE3","This study will investigate whether combining virtual reality-based mirror therapy (VRMT) and transcranial direct current stimulation (tDCS) alongside conventional physical therapy (CPT) will significantly improve hand function for patients with stroke compared to using VRMT or tDCS alone.",[27,26],[87,88],"Virtual reality, Mirror therapy, non invasive brain stimulation, tDCS, stroke","transcranial direct current stimulation","2025-01-02",{"date":91,"type":40},"2025-01-08",{"date":93,"type":40},"2023-09-19",{"date":95,"type":20},"2025-07-21",{"name":97,"class":47},"King Saud University",2]