[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"stuttering-adult\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:stuttering-adult":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,46,73,100,128,147],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100606828","organization-and-development-of-motor-cortical-circuits-for-speech-production-in-stuttering-100606828",false,"NCT07180628","Organization and Development of Motor Cortical Circuits for Speech Production in Stuttering","Inclusion Criteria:\n\n* Are between the ages of 18-65 years\n* Have otherwise normal speech, language, hearing and cognition\n* Speak English as their primary language\n* Currently stutter\n\nExclusion Criteria:\n\n* Have serious medical or neurological conditions (e.g., stroke, traumatic brain injury, Parkinson's disease, etc.)\n* Have had a closed head injury (e.g., concussion)\n* Have a reading disorder (e.g., dyslexia)\n* Have hearing loss\n* Have metal or electronic implants (e.g., cochlear implants, pacemakers, etc.)\n* Are currently pregnant","ALL","18 Years","65 Years",{"count":19,"type":20},50,"ESTIMATED","INTERVENTIONAL",[23],"NA","The overall objective of this study is to examine inter effector areas (IEAs) activity and functional connectivity during continuous speech production in stuttering adults.",[26,27,28,29],"Stutter","Stuttering, Adult","Stuttering","Stuttering, Developmental",[31,32],"Magnetic Resonance Imaging (MRI) scans","Behavioral assessments","RECRUITING","2026-04-27",{"date":36,"type":37},"2026-04-29","ACTUAL",{"date":39,"type":37},"2026-04-24",{"date":41,"type":20},"2029-03",{"name":43,"class":44},"University of Michigan","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":53,"targetDuration":4,"studyType":21,"phases":55,"briefSummary":56,"conditions":57,"keywords":58,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":45},"100622905","using-transcranial-magnetic-stimulation-to-treat-stuttering-100622905","NCT07389694","Using Transcranial Magnetic Stimulation to Treat Stuttering","Modulating Bilateral Cortical Activation In Adults Who Stutter: A Pilot Study","Inclusion Criteria:\n\n* Age from 18 to 65 years\n* Self-identifies as a person who currently stutters\n* Right-handed or left-handed\n* Normal hearing and (corrected) vision\n* Able to understand and give informed consent\n* Monolingual English speaker\n\nExclusion Criteria:\n\n* Cardiac pacemaker or pacemaker wires; neurostimulators; implanted pumps\n* Metal in the body (rods, plates, screws, shrapnel, dentures, IUD) or metallic particles in the eye\n* Facial tattoos\n* Not having medical insurance\n* Surgical clips in the head or previous neurosurgery\n* Any magnetic particles in the body\n* Cochlear implants\n* Prosthetic heart valves\n* Epilepsy or any other type of seizure history\n* History of significant head trauma (i.e., extended loss of consciousness, neurological sequelae)\n* Known structural brain lesions\n* Pre-existing speech, language, or neurological disorder (except for stuttering)\n* Significant other disease (heart disease, malignant tumors, mental disorders)\n* Significant claustrophobia; Ménière's disease\n* Women who are trying to get pregnant and sexually active women (of reproductive age) not on a reliable contraceptive\n* Pregnancy, breastfeeding\n* Medications increasing the risk for seizures\n* Non-prescribed drug use\n* Use of recreational drugs such as medical marijuana\n* Failure to perform the behavioral tasks or neuropsychological evaluation tests\n* Prisoners",{"count":54,"type":20},2,[23],"The goal of this clinical trial is to learn if repeated transcranial magnetic stimuli (rTMS) can treat stuttering in adults. The main questions it aims to answer are:\n\n* Will there be changes in the brains of people who stutter because of the treatment?\n* Will any changes in the brain result in less stuttering?\n\nParticipants will:\n\n* Visit the lab 3 times before treatment for tests\n* Complete 10 rTMS sessions\n* Visit the lab 2 times after treatment for tests",[27],[59,60,61,62,63],"stuttering","noninvasive treatment","transcranial magnetic stimulation","eye tracking","EEG","2026-02-04",{"date":66,"type":37},"2026-02-06",{"date":68,"type":20},"2026-02-15",{"date":70,"type":20},"2027-12-15",{"name":72,"class":44},"Kansas State University",{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":77,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":79,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":80,"targetDuration":4,"studyType":21,"phases":82,"briefSummary":84,"conditions":85,"keywords":86,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":45},"100609538","phase-1-dopamine-and-sensorimotor-function-in-stuttering-100609538","NCT07215884","Dopamine and Sensorimotor Function in Stuttering","Inclusion Criteria:\n\n* native speakers of American English\n* for adults who stutter, presence of stuttering will be confirmed, with onset before age 6 years\n* Normal hearing\n* Ages of 18 to 65 years\n* healthy adults without hearing-language difficulties\n\nExclusion Criteria:\n\n* self-reported speech-language-hearing difficulties other than stuttering\n* self-reported neurological or psychological problems\n* other medications (drugs that affect dopaminergic system and\u002For benzodiazepines)",true,{"count":81,"type":20},40,[83],"PHASE1","This study is being done to understand the effect of aripiprazole on adults who stutter. Stuttering is a disorder that affects speech fluency. This study aims to understand sensorimotor pathways of stuttering and possible interventions.",[27],[28,87,88,89,90],"Aripiprazole","Adults with Stuttering","Speech Fluency","Auditory Feedback","2025-10-08",{"date":93,"type":37},"2025-10-14",{"date":95,"type":37},"2025-09-30",{"date":97,"type":20},"2026-06-30",{"name":99,"class":44},"University of California, San Francisco",{"id":101,"slug":102,"hasResults":11,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":4,"eligibilityCriteria":106,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":107,"targetDuration":4,"studyType":21,"phases":109,"briefSummary":110,"conditions":111,"keywords":113,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":45},"100573030","transcranial-alternating-current-stimulation-tacs-in-stuttering-100573030","NCT06740968","Transcranial Alternating Current Stimulation (tACS) in Stuttering","Improving Neural Oscillation and Synchrony Between Motor and Auditory Regions in Stuttering Using Personalized Transcranial Alternating Current Stimulation (tACS)","Inclusion Criteria for stutterers:\n\n* Have normal language, hearing, and cognition\n* Speak English as the primary language\n* Currently stutter\n* Score (per protocol) a certain value on the Stuttering Severity Instrument (SSI-4).\n* Have not received any treatment for stuttering within the past year\n\nExclusion Criteria for stutterers:\n\n* History of seizures\n* Major medical or neurological illness (e.g., stroke, serious head trauma, brain infection, Parkinson's disease, etc.)\n* History of closed head injury with loss of consciousness (e.g., concussion)\n* Metal or electronic implants such as cochlear implants and pacemakers anywhere in the body\n* Braids or other hair styling that prevents direct access to the scalp (if removal not possible)\n* Currently pregnant",{"count":108,"type":20},80,[23],"The purpose of this study is to investigate how mild, noninvasive electrical brain stimulation affects speech relevant brain areas, which may in turn affect speech fluency and speaking-related brain activity in people that stutter. The long-term goal of this study is to test the therapeutic potential of transcranial alternating current stimulation (tACS) for the treatment of stuttering.\n\nThe study team hypothesizes that if stuttering involves impaired initiation of motor programs, delta-tuned tACS will strengthen communication between brain regions and decrease stuttering. Therefore, delta-tuned sensorimotor tACS will be paired with fluency-induced speech (choral reading), which is hypothesized to decrease stuttering via improved auditory motor integration.",[27,112,29],"Stuttering, Childhood",[114,115,116,117,118,119],"tACS","Magnetic resonance imaging","Electroencephalogram","Auditory perturbation","Neural oscillations","Brain stimulation","2025-09-05",{"date":122,"type":37},"2025-09-12",{"date":124,"type":37},"2025-08-05",{"date":126,"type":20},"2029-12",{"name":43,"class":44},{"id":129,"slug":130,"hasResults":11,"nctId":131,"briefTitle":132,"officialTitle":133,"acronym":4,"eligibilityCriteria":134,"healthyVolunteers":79,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":135,"targetDuration":4,"studyType":21,"phases":136,"briefSummary":137,"conditions":138,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":142,"completionDateStruct":144,"leadSponsor":145,"locationsCount":45},"100548549","information-processing-biases-in-adults-who-stutter-100548549","NCT06422442","Information Processing Biases in Adults Who Stutter","Information Processing Biases in Adults Who Stutter: Behavioral and Eye-tracking Indices of Threat-related Attention Allocation","Inclusion Criteria:\n\n* Speaks English as their primary language\n* Normal hearing (based on pure tone screening)\n* Normal or corrected vision (based on report)\n* Normal color vision (based on Ishihara Test, Concise Edition)\n* Nonverbal intelligence within at least average range based on Test of Nonverbal Intelligence, 4th Edition\n* Expressive language within at least average range score based on Expressive One-Word Picture Vocabulary Test\n\nAdditional inclusion criteria for adults who stutter:\n\n* Self-identification as a person who stutters\n* Score of at least 11 (mild stuttering) on Stuttering Severity Index, 4th Edition\n\nExclusion Criteria:\n\n* Reported significant medical history\n* Psychological or emotional disorder\n* History of frank neurological injury\n* Known speech, language, or learning disorder(s) other than stuttering\n* Reading difficulties\n* Score within clinically significant range for ADHD on Adults ADHD Self-Rating Scale\n* Score within clinically significant range for depression on Beck Depression Inventory\n* Score within clinically significant range for anxiety on State-Trait Anxiety Inventory",{"count":108,"type":20},[23],"The goal of this clinical trial is to examine whether stuttering is associated with a tendency to attend more quickly or for longer durations to threat-related information in the environment (threat-related attention bias). The main questions it aims to answer are:\n\nDo adults who stutter, relative to adults who do not stutter, attend to threat-related stimuli more than neutral information? Are attentional biases observed across different types of threat or are they specific to threats related to stuttering experiences? Do measures of attention bias explain individual differences in psychological reactions among adults who stutter?",[27],"2024-05-15",{"date":141,"type":37},"2024-05-21",{"date":143,"type":37},"2023-09-11",{"date":97,"type":20},{"name":146,"class":44},"University of Memphis",{"id":148,"slug":149,"hasResults":11,"nctId":150,"briefTitle":151,"officialTitle":152,"acronym":4,"eligibilityCriteria":153,"healthyVolunteers":79,"sex":15,"minAge":154,"maxAge":155,"enrollmentInfo":156,"targetDuration":4,"studyType":21,"phases":158,"briefSummary":159,"conditions":160,"keywords":161,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":163,"lastUpdatePostDateStruct":164,"startDateStruct":166,"completionDateStruct":168,"leadSponsor":170,"locationsCount":45},"100509030","exploring-the-nature-assessment-and-treatment-of-stuttering-100509030","NCT05908123","Exploring the Nature, Assessment and Treatment of Stuttering","The Blank Center CARE Model™: An Anti-Ableist Approach to Treatment","Inclusion Criteria:\n\nA participant will be considered a child who stutters (ages 2-17 years) if\n\n* their parent\u002Fcaregiver reports concern that their child is a person who stutters,\n* they exhibit three of more stuttering-like disfluencies (e.g., sound\u002Fsyllable repetitions, (in)audible sound prolongations, whole-word repetitions) per 300-word speech sample, or\n* they present with an overall score of 11 or higher on the Stuttering Severity Instrument - 4th Edition (SSI-4).\n\nA participant will be considered an adult who stutters (18+ years) if\n\n* they report they are a person who stutters,\n* they have received a formal diagnosis of stuttering from a certified speech-language pathologist,\n* they exhibit three of more stuttering-like disfluencies (e.g., sound\u002Fsyllable repetitions, (in)audible sound prolongations, whole-word repetitions) per 300-word speech sample, or\n* they present with an overall score of 11 or higher on the Stuttering Severity Instrument - 4th Edition (SSI-4).\n\nExclusion Criteria:\n\n• There are no exclusion criteria for persons who stutter.","2 Years","85 Years",{"count":157,"type":20},3000,[23],"The purposes of this study are to 1) investigate potential speech, language, and psychosocial contributions to the experience of stuttering in monolingual and multilingual speakers, and to 2) evaluate interdisciplinary, telehealth, and speech-language pathology treatment methods and clinical training specific to fluency disorders.",[28,27,112,29],[162],"stuttering, communication competence, adult, treatment","2023-06-20",{"date":165,"type":37},"2023-06-22",{"date":167,"type":37},"2015-05-22",{"date":169,"type":20},"2035-05-22",{"name":171,"class":44},"University of Texas at Austin"]