[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"stuttering-childhood\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:stuttering-childhood":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,42,73,97,127],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100560535","the-development-of-stuttering-in-young-children-100560535",false,"NCT06578416","The Development of Stuttering in Young Children","Developmental Trajectories to Stuttering Persistence and Recovery","Inclusion Criteria for controls:\n\n* English as first\u002Fprimary language\n* No history of neurological disease\n* Normal or corrected visual acuity\n* No medications expected to affect performance\n* No intellectual impairment, autism spectrum disorder, ADHD\n* Age-appropriate scores on speech and language assessment battery\n* Pass hearing screening at 20 dB at 500, 1000, 2000, and 4000, bilaterally\n\nInclusion Criteria for children who stutter:\n\n* English as first\u002Fprimary language\n* No history of neurological disease\n* Normal or corrected visual acuity\n* No medications expected to affect performance\n* No intellectual impairment or ASD Scores on speech and language assessments indicating stuttering, phonological (speech sound), or language disorders\n* Pass hearing screening at 20 dB at 500, 1000, 2000, and 4000, bilaterally",true,"ALL","3 Years","6 Years",{"count":21,"type":22},120,"ESTIMATED","OBSERVATIONAL","The goal of this longitudinal research is to learn why some children \"grow out\" of stuttering, while others persist. Children who do and do not stutter aged 3-6 years are eligible to participate in our study. During the study, children's speech and language abilities will be assessed with standardized assessments, and they complete several child-friendly experiments. During these experiments, brain activity will be recorded using specialized caps while children describe pictures, children will speak in two virtual-reality scenarios, and produce speech while keeping to a beat.",[26,27,28],"Stuttering","Stuttering, Childhood","Stuttering, Developmental","RECRUITING","2026-04-13",{"date":32,"type":33},"2026-04-16","ACTUAL",{"date":35,"type":33},"2023-06-01",{"date":37,"type":22},"2027-06",{"name":39,"class":40},"Michigan State University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":16,"sex":17,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":58,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":41},"100461247","network-connectivity-and-temporal-processing-in-adolescents-who-stutter-100461247","NCT05286151","Network Connectivity and Temporal Processing in Adolescents Who Stutter","Subcortical Network Connectivity and Temporal Processing in Children With Persistent and Recovered Stuttering","Inclusion Criteria Children who stutter:\n\n* English as primary language\n* Current or past stuttering diagnosis\n\nInclusion Criteria Children who do not stutter:\n\n* English as primary language\n\nExclusion Criteria Children who stutter:\n\n* Diagnosed\u002Funder treatment for any neurological or psychiatric conditions\n* Head trauma with loss of consciousness\n* Major medical illness\n* Hearing loss- Language\u002Fmotor delay (below -2 standard deviations on standardized assessments)\n* Face, motor, or reflex abnormalities\n\nExclusion Criteria Children who do not stutter:\n\n* Personal or family history of stuttering\n* Diagnosed\u002Funder treatment for any neurological or psychiatric conditions\n* Head trauma with loss of consciousness\n* Major medical illness\n* Hearing loss\n* Language\u002Fmotor delay (below -2 standard deviations on standardized assessments\n* Face, motor, or reflex abnormalities","9 Years","13 Years",{"count":52,"type":22},500,"INTERVENTIONAL",[55],"NA","The specific purpose of this clinical trial is to compare performance on rhythm perception and production tasks between children who stutter and children who do not stutter. The overall project also aims to investigate how performance on rhythm tasks may be related to brain activity (non-clinical trial).",[27,26],[59,60,61,62,63],"Rhythm","Temporal processing","Healthy children","Speech disorders","Timing","2025-10-21",{"date":66,"type":33},"2025-10-23",{"date":68,"type":33},"2022-07-23",{"date":70,"type":22},"2027-01-31",{"name":72,"class":40},"University of Michigan",{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":16,"sex":17,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":4,"studyType":53,"phases":84,"briefSummary":85,"conditions":86,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":96},"100490653","speech-signals-in-stuttering-100490653","NCT05668923","Speech Signals in Stuttering","Neural Processing of Speech Signals in Children Who Stutter","Inclusion Criteria:\n\n* Speaks English as primary language\n* Language abilities within the typical range\n* Cognitive abilities within the typical range\n* No contraindications for MRI\n\nInclusion criteria for children who stutter:\n\n* Presence of developmental stuttering (onset in childhood)\n* No history of other communication disorder\n\nInclusion criteria for children who do not stutter:\n\n* No family history of stuttering\n* No history of other communication disorders (e.g., hearing impairment, language impairment, cognitive impairment\u002Finjury)\n\nExclusion Criteria:\n\n* Taking medication that alters neural function\n* Cognitive skills below the typical range\n* Major medical illness\n* Not a fluent speaker of English\n* Pregnant or possibly pregnant\n* Metal implants in your body (including pacemakers, neurostimulators, or other metal objects)\n* Shrapnel injuries\n* Ocular foreign bodies (e.g., metal shavings)\n* Metal piercings that cannot be removed for the scan\n* Tattoos containing iron or metal pigments\n* Prone to claustrophobia\n* For fMRI, those with head circumference greater than 60cm or whose weight is more than 300 pounds will be excluded due to the size of the fMRI magnet bore","5 Years","17 Years",{"count":83,"type":22},600,[55],"The purpose of this research study is to understand how speech and language are processed in the brain. This study will provide information that may help with the understanding how speech and language are processed in children and whether there may be differences between children who stutter and children who do not stutter. This project will evaluate these neural processes for speech signals in children who stutter and control subjects through a battery of behavioral speech and language tests, electroencephalography-based (EEG) tasks, functional magnetic resonance imaging (fMRI), and computational modeling.",[27],"2025-09-08",{"date":89,"type":33},"2025-09-15",{"date":91,"type":33},"2022-09-21",{"date":93,"type":22},"2027-12",{"name":95,"class":40},"University of Pittsburgh",2,{"id":98,"slug":99,"hasResults":11,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":4,"eligibilityCriteria":103,"healthyVolunteers":11,"sex":17,"minAge":104,"maxAge":105,"enrollmentInfo":106,"targetDuration":4,"studyType":53,"phases":108,"briefSummary":109,"conditions":110,"keywords":112,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":41},"100573030","transcranial-alternating-current-stimulation-tacs-in-stuttering-100573030","NCT06740968","Transcranial Alternating Current Stimulation (tACS) in Stuttering","Improving Neural Oscillation and Synchrony Between Motor and Auditory Regions in Stuttering Using Personalized Transcranial Alternating Current Stimulation (tACS)","Inclusion Criteria for stutterers:\n\n* Have normal language, hearing, and cognition\n* Speak English as the primary language\n* Currently stutter\n* Score (per protocol) a certain value on the Stuttering Severity Instrument (SSI-4).\n* Have not received any treatment for stuttering within the past year\n\nExclusion Criteria for stutterers:\n\n* History of seizures\n* Major medical or neurological illness (e.g., stroke, serious head trauma, brain infection, Parkinson's disease, etc.)\n* History of closed head injury with loss of consciousness (e.g., concussion)\n* Metal or electronic implants such as cochlear implants and pacemakers anywhere in the body\n* Braids or other hair styling that prevents direct access to the scalp (if removal not possible)\n* Currently pregnant","18 Years","65 Years",{"count":107,"type":22},80,[55],"The purpose of this study is to investigate how mild, noninvasive electrical brain stimulation affects speech relevant brain areas, which may in turn affect speech fluency and speaking-related brain activity in people that stutter. The long-term goal of this study is to test the therapeutic potential of transcranial alternating current stimulation (tACS) for the treatment of stuttering.\n\nThe study team hypothesizes that if stuttering involves impaired initiation of motor programs, delta-tuned tACS will strengthen communication between brain regions and decrease stuttering. Therefore, delta-tuned sensorimotor tACS will be paired with fluency-induced speech (choral reading), which is hypothesized to decrease stuttering via improved auditory motor integration.",[111,27,28],"Stuttering, Adult",[113,114,115,116,117,118],"tACS","Magnetic resonance imaging","Electroencephalogram","Auditory perturbation","Neural oscillations","Brain stimulation","2025-09-05",{"date":121,"type":33},"2025-09-12",{"date":123,"type":33},"2025-08-05",{"date":125,"type":22},"2029-12",{"name":72,"class":40},{"id":128,"slug":129,"hasResults":11,"nctId":130,"briefTitle":131,"officialTitle":132,"acronym":4,"eligibilityCriteria":133,"healthyVolunteers":16,"sex":17,"minAge":134,"maxAge":135,"enrollmentInfo":136,"targetDuration":4,"studyType":53,"phases":138,"briefSummary":139,"conditions":140,"keywords":141,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":143,"lastUpdatePostDateStruct":144,"startDateStruct":146,"completionDateStruct":148,"leadSponsor":150,"locationsCount":41},"100509030","exploring-the-nature-assessment-and-treatment-of-stuttering-100509030","NCT05908123","Exploring the Nature, Assessment and Treatment of Stuttering","The Blank Center CARE Model™: An Anti-Ableist Approach to Treatment","Inclusion Criteria:\n\nA participant will be considered a child who stutters (ages 2-17 years) if\n\n* their parent\u002Fcaregiver reports concern that their child is a person who stutters,\n* they exhibit three of more stuttering-like disfluencies (e.g., sound\u002Fsyllable repetitions, (in)audible sound prolongations, whole-word repetitions) per 300-word speech sample, or\n* they present with an overall score of 11 or higher on the Stuttering Severity Instrument - 4th Edition (SSI-4).\n\nA participant will be considered an adult who stutters (18+ years) if\n\n* they report they are a person who stutters,\n* they have received a formal diagnosis of stuttering from a certified speech-language pathologist,\n* they exhibit three of more stuttering-like disfluencies (e.g., sound\u002Fsyllable repetitions, (in)audible sound prolongations, whole-word repetitions) per 300-word speech sample, or\n* they present with an overall score of 11 or higher on the Stuttering Severity Instrument - 4th Edition (SSI-4).\n\nExclusion Criteria:\n\n• There are no exclusion criteria for persons who stutter.","2 Years","85 Years",{"count":137,"type":22},3000,[55],"The purposes of this study are to 1) investigate potential speech, language, and psychosocial contributions to the experience of stuttering in monolingual and multilingual speakers, and to 2) evaluate interdisciplinary, telehealth, and speech-language pathology treatment methods and clinical training specific to fluency disorders.",[26,111,27,28],[142],"stuttering, communication competence, adult, treatment","2023-06-20",{"date":145,"type":33},"2023-06-22",{"date":147,"type":33},"2015-05-22",{"date":149,"type":22},"2035-05-22",{"name":151,"class":40},"University of Texas at Austin"]