[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"subacute-stroke\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:subacute-stroke":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,13,0,[8,41,74,104,131,154,182,211,234,265,291,324,350],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100631656","personalized-music-enhanced-aerobic-training-for-patients-in-subacute-stroke-recovery-100631656",false,"NCT07503522","Personalized Music-Enhanced Aerobic Training for Patients in Subacute Stroke Recovery","Evaluation of the Effectiveness of a Personalized Music-Based Aerobic Exercise Rehabilitation Program for Patients With Subacute Stroke","AMPER-Stroke","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* Clinically and radiologically confirmed diagnosis of subacute stroke.\n* Able to understand and respond to assessment questions.\n* No significant visual or hearing impairment.\n* Mini-Mental State Examination (MMSE) ≥ 10.\n* Able to sit unsupported.\n* Provided informed consent (patient or legal representative).\n\nExclusion Criteria:\n\n* Recent myocardial infarction or congestive heart failure.\n* Severe cardiac arrhythmia or resting systolic blood pressure \\> 200 mmHg.\n* Hypertrophic cardiomyopathy or severe aortic stenosis.\n* Musculoskeletal disorders contraindicating exercise.\n* Psychiatric disorders interfering with participation.\n* Severe aphasia preventing assessment.\n* Moderate-to-severe dementia (MMSE ≤ 9).","ALL","18 Years",{"count":20,"type":21},92,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to evaluate the effectiveness of a personalized music-based aerobic exercise program designed specifically for inpatients in the subacute phase of stroke. All participants will receive the hospital's standard physical therapy program. In addition, the intervention group will participate in 30-minute music-based aerobic exercise sessions, 5 days per week, for a total of 6 weeks.\n\nThe aerobic exercises are gentle and adapted to the functional abilities of individuals with subacute stroke. The exercises incorporate rhythmic music to guide movements of the arms, legs, and trunk, with the goal of improving mobility, balance, and mood. Participants will have their heart rate monitored and will be supervised directly by rehabilitation therapists throughout all sessions to ensure safety.\n\nOutcomes will be assessed before and after the 6-week intervention using standardized measures of motor function, balance, depressive symptoms, and independence in daily activities. The study does not interfere with participants' routine medical treatment and does not require discontinuation of any ongoing therapies.\n\nRisks associated with participation are generally mild and similar to those of routine therapeutic exercise, such as muscle soreness, dizziness, or risk of falls. All potential risks will be minimized through continuous supervision by trained healthcare staff. Participants may withdraw from the study at any time.\n\nPotential benefits for participants include improved mobility, better balance, reduced depressive symptoms, increased independence in daily living, and enhanced motivation during rehabilitation through the use of music. The study also aims to provide scientific evidence for the effectiveness of music-based aerobic exercise in stroke rehabilitation in Vietnam.",[27],"Subacute Stroke","RECRUITING","2026-04-08",{"date":31,"type":32},"2026-04-13","ACTUAL",{"date":34,"type":32},"2026-04-01",{"date":36,"type":21},"2028-05",{"name":38,"class":39},"Trịnh Minh Tú","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":17,"minAge":48,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":22,"phases":51,"briefSummary":52,"conditions":53,"keywords":55,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":40},"100630696","ai-based-customized-tdcs-for-finger-motor-recovery-after-subacute-stroke-100630696","NCT07491029","AI-based Customized tDCS for Finger Motor Recovery After Subacute Stroke","A Multi-center, Randomized, Double-blind, Prospective, Superiority Clinical Trial to Evaluate the Safety and Effectiveness of Artificial Intelligence-based Customized Transcranial Direct Current Stimulation Using MR Images for Improving Finger Motor Function in Patients With Finger Paralysis Due to Subacute Stroke","Inclusion Criteria:\n\nParticipants must meet all of the following criteria to be eligible for this clinical trial:\n\n1. Adults aged 19 years or older\n2. Patients with stroke confirmed by brain imaging\n3. Subacute stroke patients within 2 weeks to 3 months after stroke onset\n4. Patients with unilateral upper-extremity paralysis\n5. Upper-extremity Fugl-Meyer Assessment (FMA-UE, maximum score 66) score between 20 and 56\n6. Participants who voluntarily provide written informed consent after receiving and understanding the study procedures and requirements\n\nExclusion Criteria:\n\nParticipants will be excluded if they meet any of the following criteria:\n\n1. History of a condition affecting the function of the paralyzed arm\n2. Inability to follow instructions or complete the study due to cognitive impairment or aphasia\n3. Evidence of delirium, confusion, or other disorders of consciousness\n4. Presence of uncontrolled medical or surgical conditions\n5. Severe neurological disorders associated with major psychiatric conditions (e.g., major depressive disorder, schizophrenia, bipolar disorder, or dementia)\n6. History of uncontrolled epilepsy (seizure disorder)\n7. Contraindications to transcranial direct current stimulation (tDCS), including:\n\n   * Scalp disease or metal materials at the electrode attachment site\n   * Presence of a cardiac pacemaker or cochlear implant\n8. Medical contraindications to MRI examination\n9. Pregnant or breastfeeding women, or those planning pregnancy during the study period\n10. Use of a stimulation device similar to the investigational device or participation in a related clinical study within the past 1 year\n11. Individuals judged by the investigator to be medically or ethically unsuitable for participation in this clinical study","19 Years",{"count":50,"type":21},116,[24],"The goal of this clinical study is to evaluate whether AI-based customized transcranial direct current stimulation (tDCS) using MR images is more effective than sham stimulation in improving finger motor function in patients with finger paralysis caused by subacute stroke. The main questions it aims to answer are:\n\n* Does AI-based customized tDCS improve finger motor function compared with sham stimulation?\n* What medical problems or adverse events occur when participants receive AI-based customized tDCS?\n\nResearchers will compare AI-based customized tDCS with sham stimulation (a look-alike stimulation that delivers no electrical current) to determine whether the intervention improves finger motor recovery in patients with subacute stroke.",[27,54],"Upper Extremity Function",[56,57,58,59,60,61,62],"tDCS","stroke","rehabilitation","finger paralysis","upper extremity","transcranial direct current stimulation","upper limb motor function","NOT_YET_RECRUITING","2026-03-19",{"date":66,"type":32},"2026-03-24",{"date":68,"type":21},"2026-04-30",{"date":70,"type":21},"2027-12-31",{"name":72,"class":73},"NEUROPHET","INDUSTRY",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":22,"phases":83,"briefSummary":85,"conditions":86,"keywords":90,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":40},"100629016","phase-1-phase-i-split-belt-treadmill-dosing-for-subacute-stroke-100629016","NCT07469163","Phase I Split-Belt Treadmill Dosing for Subacute Stroke","NeuroRecoVR: Phase I Split-Belt Treadmill Dosing for Subacute Stroke","Inclusion Criteria:\n\n* Ischemic or hemorrhagic stroke survivors\n* First stroke\n* Over 18 years old\n* Between one week and three months post-stroke\n* can understand task instructions.\n\nExclusion Criteria:\n\n* History of significant neurological diseases (e.g. Multiple Sclerosis, Parkinson's disease)\n* Orthopedic issues in lower extremities (e.g. severe knee Osteoarthritis)\n* Excessive pain preventing participants from participating in treadmill-based activities\n* Cerebellar stroke\n* Body weight more than 560 lbs (this exceeds the weight limit of the support harness)",{"count":82,"type":21},72,[84],"PHASE1","After experiencing a stroke, many individuals encounter difficulties with walking and balance, which can significantly impact their independence. Recent studies have indicated that split-belt treadmill (SBT) training is effective for improving gait metrics, including walking speed and step length asymmetry. The SBT allows each leg to move at different speeds, which has been shown to help chronic stroke survivors learn to walk more symmetrically. However, there is limited knowledge about the dose participants should receive and the safety of SBT training in the early stages of recovery, which is a crucial period for rehabilitation. To address this gap, we are evaluating an innovative SBT with virtual reality (VR) features at the Foothills Medical Center. Our objective is to conduct a study to determine the amount of SBT training patients can tolerate in a day. In this study, stroke survivors will engage in a series of walking exercises on the SBT. We will escalate the duration of SBT walking until participants reach a point where they can no longer continue due to dose-limiting criteria such as fatigue or discomfort. The findings from this initial phase will guide future larger trials to explore the effectiveness of this training method. Ultimately, we aspire to improve rehabilitation strategies for stroke survivors, assisting them in regaining mobility and enhancing their quality of life more effectively.",[27,87,88,89],"Stroke","Stroke (Subacute)","Stroke Gait Rehabilitation",[57,91,92,93,94],"subacute stroke","split belt treadmill","gait rehabilitation","stroke recovery","2026-03-09",{"date":97,"type":32},"2026-03-13",{"date":99,"type":32},"2026-03-01",{"date":101,"type":21},"2026-08-31",{"name":103,"class":39},"University of Calgary",{"id":105,"slug":106,"hasResults":11,"nctId":107,"briefTitle":108,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":110,"enrollmentInfo":111,"targetDuration":4,"studyType":22,"phases":113,"briefSummary":114,"conditions":115,"keywords":119,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":127,"leadSponsor":129,"locationsCount":40},"100626310","changes-in-hemodynamic-response-following-transcranial-electrical-stimulation-in-sroke-individuals-100626310","NCT07433972","Changes in Hemodynamic Response Following Transcranial Electrical Stimulation in Sroke Individuals","Inclusion Criteria:\n\n1. Unilateral stroke individuals aged 18-80 years.\n2. A first-ever stroke.\n3. Stroke onset from at least 2 weeks-5 years.\n4. Able to walk independently with or without gait aids (modified Rankin scale (mRS) 1-3)\n5. Montreal cognitive Assessment-Thai version (MoCA-T) greater than or equal to 20 scores.\n6. Ability to read, communicate, follow and understand instructions.\n\nExclusion Criteria:\n\n1. Presence of any psychological or neurological antecedent, unstable medical conditions or condition that may increase risk of stimulation such as epilepsy, seizure, and history of brain injury\n2. Having unstable cardiovascular disease or respiratory disease, and uncontrolled chronic disease such as diabetes mellitus (DM), hypertension (HT) and chronic kidney disease (CKD)\n3. Receiving other non-invasive brain stimulation or additional intervention such as TMS, PMS or acupuncture\n4. Presence of metal implantation, intracranial shunt, cochlear implantation, or cardiac pacemakers.\n5. Presence of an opened wound, infectious wound around scalp or craniectomy with unreplaced bone flap\n6. Moderate pain (numeric pain rating score \\> 4\u002F10) in any joint of the upper or lower limb, whether paretic or non-paretic\n7. Presence of color blindness\n8. Presence of any substance use including cannabis and kratom","80 Years",{"count":112,"type":21},60,[24],"The present study will use transcranial electrical stimulation (tES) which are transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) combined with conventional physical therapy and cognitive-motor dualt ask gait training in sub-acute (at least 2 weeks after stroke onset) to chronic stroke (within 5 years post-stroke) to investigate changes in brain hemodynamics (oxy-hemoglobin and deoxy-hemoglobin concentration) as measured by functional near infrared spectroscopy (fNIRS). The findings may provides insights changes in combining tES with rehabilitation on improvements in brain hemodynamics in sub-acute to chronic stroke.",[116,117,27,118],"Hemorrhagic Stroke","Ischemic Stroke","Chronic Stroke Survivors",[87,120,121,122],"functional near-infrared spectroscopy","rehbailitation","transcranial electrical stimulation","2026-02-19",{"date":125,"type":32},"2026-02-25",{"date":99,"type":21},{"date":128,"type":21},"2026-12-30",{"name":130,"class":39},"Mahidol University",{"id":132,"slug":133,"hasResults":11,"nctId":134,"briefTitle":135,"officialTitle":136,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":110,"enrollmentInfo":137,"targetDuration":4,"studyType":22,"phases":138,"briefSummary":139,"conditions":140,"keywords":142,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":147,"startDateStruct":149,"completionDateStruct":151,"leadSponsor":153,"locationsCount":40},"100611102","effects-of-tes-combined-with-cmdt-gait-training-on-cognition-cortical-activity-spinal-motoneuron-excitability-and-motor-performance-in-stroke-individuals-100611102","NCT07236216","Effects of tES Combined With CMDT Gait Training on Cognition, Cortical Activity, Spinal Motoneuron Excitability and Motor Performance in Stroke Individuals","Effects of Transcranial Electrical Stimulation (tES) Combined With Cognitive-motor Dual-task Gait Training on Cortical Activity, Spinal Motoneuron Excitability, Cognition and Motor Performance in Stroke Individuals",{"count":112,"type":21},[24],"The present study will use transcranial electrical stimulation (tES) which are transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) combined with conventional physical therapy and cognitive-motor dual task gait training in sub-acute (at least 2 weeks after stroke onset) to chronic (within 5 years post-stroke) to investigate the effect on cortical activity, spinal motoneuron excitability, cognition and motor performance. The findings may enhance the evidence to support usages of tES for improvimg cognition, motor performance as well as cortical activity and spinal motoneuron excitability in a clinical setting.",[116,117,27,141],"Chronic Stroke Patient",[57,143,144,58,145,146],"electroencephalography","event related potentials","gait training","High-definition transcranial electrical stimulation",{"date":148,"type":32},"2026-02-23",{"date":150,"type":32},"2025-12-20",{"date":152,"type":21},"2027-12-30",{"name":130,"class":39},{"id":155,"slug":156,"hasResults":11,"nctId":157,"briefTitle":158,"officialTitle":159,"acronym":160,"eligibilityCriteria":161,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":162,"targetDuration":4,"studyType":22,"phases":164,"briefSummary":165,"conditions":166,"keywords":167,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":173,"lastUpdatePostDateStruct":174,"startDateStruct":176,"completionDateStruct":178,"leadSponsor":180,"locationsCount":40},"100590817","efficacy-of-treadmill-walking-with-hidden-vision-for-rehabilitation-in-the-subacute-phase-of-stroke-100590817","NCT06972355","Efficacy of Treadmill Walking With Hidden Vision for Rehabilitation in the Subacute Phase of Stroke","Efficacy of Treadmill Walking With Hidden Vision for Rehabilitation in the Subacute Phase of Stroke, Randomized Controlled Trial","MAVREEC","Inclusion Criteria:\n\n1. 18 years of age or older,\n2. With a confirmed diagnosis of ischemic or hemorrhagic stroke in sub-acute phase (stroke less than 6 months old),\n3. With NIHSS scores between 1 and 15 and MoCA scores between 18 and 30\n4. With a physiotherapy prescription for post Stroke rehabilitation\n5. Able to walk for 20 min on a treadmill with weight reduction with pauses, able to maintain bipodal balance, able to maintain bipodal balance with eyes open and closed for 30 seconds,\n6. Having expressed free, informed and written consent\n7. Affiliated with a social security scheme.\n\nExclusion Criteria:\n\n1. Patients weighing over 200 kg (maximum weight permitted for use of the Lite Gait ®),\n2. Patients with impaired vision:\n\n   1. Best corrected visual acuity below 5\u002F10 on patient examination\n   2. Homonymous lateral hemianopia, quadranopia.\n3. Inability to physically participate in intensive rehabilitation due to severe, unstabilized and comorbidities (heart, lung, kidney disease or diabetes), severe psychiatric disorders cancer active or under treatment.\n4. Patients participating in other interventional research,\n5. Pregnant or breast-feeding women,\n6. Patients under guardianship.",{"count":163,"type":21},36,[24],"Objective: The aim of this study is to compare the efficiency of vision-obscured versus vision-retained treadmill gait training in subacute post-stroke patients.\n\nMethodology: Thirty-six patients with stroke (ischemic or hemorrhagic) less than six months old will be included and randomized into two parallel groups. The experimental group will undergo treadmill gait training using an opaque mask, combined with body weight reduction (Lite Gait® harness). The control group will follow the same walking protocol, but with their eyes open. Each session will last 20 minutes, integrated into one hour of rehabilitation, at a rate of three sessions per week for six weeks. Assessment will include single- and double-task walking speed, balance parameters and proprioception.\n\nExpected results: The hypothesis is that visual deprivation will stimulate the proprioceptive and vestibular systems to a greater extent, resulting in benefits for postural balance, walking and proprioception. The main hypothesis will be the improvement in the difference between single-task and double-task walking speed. Analyses will be conducted on an intention-to-treat basis, using statistical tests adapted to the nature of the variables.\n\nConclusion: This study could highlight the value of temporary visual suppression as a therapeutic lever in stroke rehabilitation.",[27],[87,168,169,170,171,172],"Gait","Treadmill","Double task","Proprioception","Postural balance","2025-09-30",{"date":175,"type":32},"2025-10-01",{"date":177,"type":32},"2025-06-04",{"date":179,"type":21},"2027-07-19",{"name":181,"class":39},"Centre Hospitalier Régional Metz-Thionville",{"id":183,"slug":184,"hasResults":11,"nctId":185,"briefTitle":186,"officialTitle":187,"acronym":4,"eligibilityCriteria":188,"healthyVolunteers":11,"sex":17,"minAge":189,"maxAge":190,"enrollmentInfo":191,"targetDuration":4,"studyType":22,"phases":193,"briefSummary":194,"conditions":195,"keywords":196,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":203,"lastUpdatePostDateStruct":204,"startDateStruct":206,"completionDateStruct":208,"leadSponsor":209,"locationsCount":40},"100587347","segmental-vibrator-with-nmes-on-lower-limb-function-in-subacute-stroke-100587347","NCT06927206","Segmental Vibrator With NMES on Lower Limb Function in Subacute Stroke","Combined Effects of Segmental Vibrator With Neuromuscular Electrical Stimulation for Dorsiflexors on Lower Limb Function in Subacute Stroke","Inclusion Criteria:\n\n* Both male and female patients were included in the study.\n* The age range of participants was between 45 and 60 years.\n* Participants that were diagnosed with ischemic stroke patient.\n* Participants had experienced sub-acute ischemic stroke, specifically 15 days to 12 weeks post-stroke.\n* Montreal Cognitive Assessment scores falling within the range of 18-24 were necessary.\n* Modified Ashworth scale scores had to be less than +1\n* National Institutes of Health Stroke Scale (NIHSS) score falling within the range of 1 to 15 were necessary.\n* Participants feel no pain from the vibrator.\n* It was anticipated that participants would either be able to give informed consent or have a legal representative who could do so.\n\nExclusion Criteria:\n\n* People who had a history of serious neurological or mental conditions that would have impeded lower limb motor recovery-aside from stroke-were not included.\n* Individuals with severe arthritis or joint injuries, among other illnesses that would have interfered with treatment or evaluations, were not allowed to participate.\n* Individuals who had significant hearing or vision impairments that would have hampered treatment or evaluations were not included.\n* Individuals undergoing anti-spatial therapy or other clinical trials, those with bilateral brain lesions, and those with ischemic involvement of the cerebellum or basal ganglia were not allowed to participate.\n* Participants having metal implants e. g cardiac pacemaker and skin lesion at the site of stimulation electrodes were excluded.","45 Years","60 Years",{"count":192,"type":21},50,[24],"Stroke is one of the world's leading causes of death and disability. It can cause a variety of motor disorders, such as apraxia, sensory deficits, abnormal muscle tone, inadequate weight transfer, lack of fine motor skills, incoordination, and balance deficit. These disorders can have a significant negative impact on a person's quality of life.",[27,117],[197,198,199,200,87,201,202],"Dorsiflexion","FMA","NEMS","Segmental muscle vibrator","Spasticity","Vibration","2025-08-18",{"date":205,"type":32},"2025-08-19",{"date":207,"type":32},"2025-04-10",{"date":173,"type":21},{"name":210,"class":39},"Riphah International University",{"id":212,"slug":213,"hasResults":11,"nctId":214,"briefTitle":215,"officialTitle":216,"acronym":4,"eligibilityCriteria":217,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":218,"targetDuration":4,"studyType":22,"phases":219,"briefSummary":220,"conditions":221,"keywords":222,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":226,"lastUpdatePostDateStruct":227,"startDateStruct":229,"completionDateStruct":231,"leadSponsor":232,"locationsCount":40},"100573932","migo-tracker-remote-monitoring-of-home-exercise-after-stroke-100573932","NCT06752707","MiGo Tracker Remote Monitoring of Home Exercise After Stroke","MiGo Tracker: Seamless Remote Therapeutic Monitoring of Exercise Adherence After Stroke","Inclusion Criteria:\n\n* Experienced one or more strokes less than one month (30 days) prior\n* Upper Extremity Fugl-Meyer Score \\> 5 and \\\u003C= 55 out of 66\n* Absence of moderate to severe pain (\\\u003C= 4 on the 10 point visual-analog pain scale)\n\nExclusion Criteria:\n\n* age \\\u003C18 years old\n* Unable to follow 2-step commands\n* Other neurological diagnosis (e.g. Parkinson's Disease)\n* Other severe concurrent medical conditions that may prevent the participants from completing the 3-month study",{"count":192,"type":21},[24],"This project will determine the safety and effectiveness of a MiGo Tracker RTM program in a randomized controlled trial with individuals with subacute stroke (N=50). Participants will be randomly assigned to either the MiGo Tracker RTM program (intervention group) or prescription of home exercises with no monitoring (usual care\u002Fcontrol group). All participants will still receive usual post-stroke care, including outpatient rehabilitation. The main question this study aims to answer is: Does a MiGo Tracker RTM program lead to significantly greater motor recovery at three-months post stroke than the usual care group. If successful, MiGo Tracker will lead to increased home exercise adherence and improved health outcomes for thousands of individuals following stroke.",[27],[223,87,224,225],"Remote Therapeutic Monitoring","Home Exercise Therapy","MiGo Tracker","2025-07-11",{"date":228,"type":32},"2025-07-16",{"date":230,"type":32},"2025-06-11",{"date":101,"type":21},{"name":233,"class":73},"Flint Rehabilitation Devices, LLC",{"id":235,"slug":236,"hasResults":11,"nctId":237,"briefTitle":238,"officialTitle":239,"acronym":4,"eligibilityCriteria":240,"healthyVolunteers":11,"sex":17,"minAge":241,"maxAge":242,"enrollmentInfo":243,"targetDuration":4,"studyType":22,"phases":245,"briefSummary":246,"conditions":247,"keywords":252,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":257,"lastUpdatePostDateStruct":258,"startDateStruct":260,"completionDateStruct":262,"leadSponsor":263,"locationsCount":40},"100593753","effect-of-virtual-reality-based-music-therapy-on-cognitive-and-motor-skills-in-subacute-stroke-patients-100593753","NCT07010536","Effect of Virtual Reality-Based Music Therapy on Cognitive and Motor Skills in Subacute Stroke Patients","Effect of Immersive Virtual Reality-Based Music Therapy on Cognitive and Motor Skills in Subacute Stroke Patients","Inclusion Criteria:\n\n* Voluntary participation\n* Age between 50 and 75 years\n* Stroke onset more than 2 weeks and less than 6 months prior\n* Diagnosis of unilateral hemiplegic stroke\n* Preserved understanding, hearing, and speech abilities sufficient to engage with virtual reality games\n\nExclusion Criteria:\n\n* Medically unstable condition\n* Wheelchair use or inability to sit in a chair\n* Cognitive impairment preventing comprehension of study procedures\n* Hearing loss\n* Severe visual impairment\n* Refusal to participate in the study\n* Epilepsy\n* Migraine with aura\n* History of motion sickness","50 Years","75 Years",{"count":244,"type":21},30,[24],"This clinical trial aims to investigate the effects of immersive virtual reality-based music therapy on cognitive and motor functions in individuals aged 50 to 75 years with subacute stroke (between 2 weeks and 6 months post-stroke). Participants will be randomly assigned to either a control group receiving conventional physiotherapy or an experimental group receiving conventional physiotherapy plus virtual reality-based music therapy.\n\nThe study will assess cognitive performance, upper extremity motor skills, stroke impact, balance, and spatial neglect before and after a 6-week intervention. All participants will be treated at Istanbul Aydın University VM Medical Park Hospital. The study has been approved by the ethics committee, and written informed consent will be obtained from all participants.",[87,27,248,249,250,251],"Virtual Reality","Immersive Virtual Reality","Cognitive Dysfunction","Motor Impairment",[87,253,248,254,255,256],"Music Therapy","Cognition Disorders","Motor Skills Disorders","Postural Balance","2025-05-30",{"date":259,"type":32},"2025-06-08",{"date":261,"type":32},"2025-03-22",{"date":150,"type":21},{"name":264,"class":39},"Suzan Aydın",{"id":266,"slug":267,"hasResults":11,"nctId":268,"briefTitle":269,"officialTitle":269,"acronym":4,"eligibilityCriteria":270,"healthyVolunteers":11,"sex":17,"minAge":189,"maxAge":4,"enrollmentInfo":271,"targetDuration":4,"studyType":22,"phases":272,"briefSummary":273,"conditions":274,"keywords":279,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":282,"lastUpdatePostDateStruct":283,"startDateStruct":285,"completionDateStruct":287,"leadSponsor":289,"locationsCount":40},"100588894","effect-of-action-observation-therapy-in-comparison-to-motor-relearning-program-on-balance-and-mobility-among-subacute-stroke-patients-100588894","NCT06947343","Effect of Action Observation Therapy in Comparison to Motor Relearning Program on Balance and Mobility Among Subacute Stroke Patients","Inclusion Criteria:\n\n* Both genders, male and female\n* Ischemic stroke patients\n* Age 45 years and above\n* MMSE\\>24\n* Able to stand independently for 1 minute\n* Patient can maintain starting sitting static position for 10 seconds without arm rest\n\nExclusion Criteria:\n\n* Any other neurological disorder\n* Orthopedic conditions(fracture) affecting balance and mobility\n* Visual or auditory impairments",{"count":244,"type":21},[24],"This study is a randomized controlled trial. The purpose of this study is to determine the effect of Action Observation Therapy in Comparison to a Motor Relearning Program on Balance and Mobility among subacute stroke patients.",[27,275,276,277,278],"Cerebral Stroke","Cerebrovascular Stroke","Posture","Functional Performance",[280,281],"Action observation therapy","Motor relearning program","2025-04-20",{"date":284,"type":32},"2025-04-27",{"date":286,"type":32},"2024-07-22",{"date":288,"type":21},"2025-06-15",{"name":290,"class":39},"Foundation University Islamabad",{"id":292,"slug":293,"hasResults":11,"nctId":294,"briefTitle":295,"officialTitle":296,"acronym":297,"eligibilityCriteria":298,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":299,"targetDuration":4,"studyType":22,"phases":301,"briefSummary":302,"conditions":303,"keywords":305,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":315,"lastUpdatePostDateStruct":316,"startDateStruct":318,"completionDateStruct":320,"leadSponsor":322,"locationsCount":40},"100572035","aggregated-system-of-sensors-and-multimedia-monitors-technology-for-innovation-and-personalization-of-rehabilitation-care-roommate-100572035","NCT06728020","AggRegated System Of sensOrs and Multimedia Monitors: Technology for innovAtion and personalizaTion of rEhabilitation Care. (ROOMMATE)","ROOMMATE - AggRegated System Of sensOrs and Multimedia Monitors: Technology for innovAtion and personalizaTion of rEhabilitation Care.","ROOMMATE","Inclusion Criteria:\n\n* outcome of ischemic or hemorrhagic stroke in subacute phase (\\\u003C 3 months after the event)\n* willingness to participate in the project, with informed consent signed by the subject or, when necessary, by the support administrator.\n\nExclusion Criteria:\n\n* severe visual and\u002For auditory impairments that cannot be corrected\n* severe cognitive and\u002For speech impairments that interfere with the ability to use the HKK system and the SensoMode accessory independently and\u002For in the\n* absence of a caregiver who can assist the patient in using the system;\n* skin lesions that prevent wearing the inertial sensors;\n* presence of signs of clinical instability, defined by a score greater than zero on the Clinical Instability Scale (SIC).",{"count":300,"type":21},200,[24],"The aim of this clinical trial is to assess whether the ROOMMATE system can effectively support the rehabilitation of adults recovering from subacute strokes. The study will be conducted at the neuromotor rehabilitation inpatient clinics of IRCCS Fondazione Don Carlo Gnocchi in Florence, Italy, and the rehabilitation inpatient unit of Elias University Emergency Hospital in Bucharest, Romania.\n\nPrimary Objectives:\n\n-To assess the effects on functional recovery in subacute stroke survivors of a technological rehabilitation station placed at patients' bedsides, combined with dedicated coaching provided to all users (patients, informal caregivers, and formal caregivers).\n\nSecondary Objectives:\n\n* Evaluation of the effects of the experimental treatment on patient satisfaction, upper limb motor skills, manual dexterity, global cognitive functioning, anxiety, and depression.\n* Assessment of user experience, acceptance, and usability of the technology by patients and caregivers.\n* Evaluation of social impact using the Social Return on Investment (SROI) ratio of the experimental treatment.\n\nParticipants randomized into one of the experimental groups, in addition to receiving conventional care, will use the ROOMMATE system during their hospitalization. The system will be made available to patients and will be free for them to use at their discretion.\n\nThe station will include:\n\nMultimedia monitors (Khymeia home kit): These will deliver cognitive and motor serious games, educational and rehabilitative content, as well as infotainment specifically developed by the clinical partners of the project.\n\nAn inertial sensor kit: This integrates with the monitors to guide users through virtual reality environments.",[27,304],"Stroke; Subacute",[91,306,307,308,309,310,311,312,313,314],"Neurorehabilitation","Assistive\u002Frehabilitation robotics","Digital health","Continuum of care","People-centered care","Accessible care","Innovation adoption","cmRCT","Enriched environment","2025-03-18",{"date":317,"type":32},"2025-03-21",{"date":319,"type":21},"2025-04",{"date":321,"type":21},"2026-05",{"name":323,"class":39},"Francesca Cecchi",{"id":325,"slug":326,"hasResults":11,"nctId":327,"briefTitle":328,"officialTitle":328,"acronym":4,"eligibilityCriteria":329,"healthyVolunteers":11,"sex":17,"minAge":189,"maxAge":190,"enrollmentInfo":330,"targetDuration":4,"studyType":22,"phases":332,"briefSummary":333,"conditions":334,"keywords":337,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":342,"lastUpdatePostDateStruct":343,"startDateStruct":345,"completionDateStruct":347,"leadSponsor":349,"locationsCount":40},"100573647","additional-effects-of-functional-muscle-training-with-turning-based-specific-training-during-turning-in-post-stroke-patients-100573647","NCT06749002","Additional Effects of Functional Muscle Training With Turning Based Specific Training During Turning in Post Stroke Patients","Inclusion Criteria:\n\n* Age group: 45-60 years onwards\n* Both males and females\n* Subacute and chronic stroke (MCA \\>6months)\n* MMSE score 25 or higher.\n* FAC -3\n\nExclusion Criteria:\n\n* Hemorrhagic stroke.\n* Patients with Epilepsy.\n* Patients with other neurological conditions like Alzheimer, Parkinson and other Dementias.",{"count":331,"type":21},32,[24],"Stroke is the leading cause of disability leading to Gait and balance dysfunction leading to decreased Quality of Life. Difficulty in turning is a major target in Gait Rehabilitation. Task specific exercises has proven to be effective in all stages of stroke rehabilitation, therefore Turning based specific training is to be used in order to improve turning and balance in post stroke patients moreover functional strength training of lower extremities prove to be more effective than traditional training.",[27,335,336],"Chronic Stroke","Balance",[87,338,339,340,341],"chronic stroke","functional muscle training","Turning based specific training","Turning in Gait","2024-12-19",{"date":344,"type":32},"2024-12-27",{"date":346,"type":32},"2024-06-20",{"date":348,"type":21},"2025-01-20",{"name":290,"class":39},{"id":351,"slug":352,"hasResults":11,"nctId":353,"briefTitle":354,"officialTitle":354,"acronym":4,"eligibilityCriteria":355,"healthyVolunteers":11,"sex":17,"minAge":356,"maxAge":357,"enrollmentInfo":358,"targetDuration":4,"studyType":22,"phases":360,"briefSummary":361,"conditions":362,"keywords":368,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":374,"lastUpdatePostDateStruct":375,"startDateStruct":377,"completionDateStruct":378,"leadSponsor":379,"locationsCount":40},"100567889","additional-effects-of-kinesio-taping-along-with-conservative-physical-therapy-on-upper-limb-function-range-of-motion-and-spasticity-in-the-patients-with-subacute-stroke-100567889","NCT06674057","Additional Effects of Kinesio-Taping Along with Conservative Physical Therapy on Upper Limb Function, Range of Motion and Spasticity in the Patients with Subacute Stroke","Inclusion Criteria:\n\n* Age group: 40-65 years onwards\n* Both males and females\n* Patients with history of diagnosed stroke and lie within subacute stage of stroke\n* MAS scale score of 1\\_2\n\nExclusion Criteria:\n\n* Any congenital deformities\n* cognitive deficits\n* Fractures\n* Upper limb surgery","40 Years","65 Years",{"count":359,"type":21},40,[24],"A randomized control trial will be done on diagnosed stroke patients of subacute stage in Fauji Foundation Hospital Rawalpindi and leading edge physical therapy and rehabilitation clinic.The purpose of the study is to determine Additional Effects of Kinesio-Taping along with conservative Physical Therapy on upper limb function, Range of motion and Spasticity in the patients with Subacute Stroke. The conservational physical therapy includes Passive and active ROMs 25 repetitions each, 3 times per week. PNF stretching (hold relax) for spastic muscles for 20 repetitions with a 10 second hold and 10 second relaxation of the muscle group 3 times per week.\n\nD1 flexion and extension for 20 repetitions 3 times per week. Kinesio tape 3 times per week. (Anchor opposed to effected compartment to provide facilitation and sustained stretch). with srtrngth training included in week 3-6 with a resistance band of medium resistance.\n\ntreatment time will be 30 minutes on alternate days for six weeks.",[27,363,364,201,365,366,87,367],"Upper Limb","Range of Motion","CVA (Cerebrovascular Accident)","KINESIOTAPING","Function",[369,91,370,371,372,373],"Stroke.","kinesio taping","proprioceptive neuromuscular facilitation","Upper limb function.","range of motion","2024-11-04",{"date":376,"type":32},"2024-11-05",{"date":346,"type":32},{"date":348,"type":21},{"name":290,"class":39}]