[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"subarachnoid-hemorrhage-spontaneous\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:subarachnoid-hemorrhage-spontaneous":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,38],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":20,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":25,"whyStopped":4,"lastUpdateSubmitDate":26,"lastUpdatePostDateStruct":27,"startDateStruct":30,"completionDateStruct":32,"leadSponsor":34,"locationsCount":37},"100630011","multicenter-registry-of-patients-with-subarachnoid-hemorrhage-100630011",false,"NCT07482124","Multicenter Registry of Patients With Subarachnoid Hemorrhage","MEASURE","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Spontaneous subarachnoid hemorrhage with blood in the basal cisterns and\u002For major fissures on non-contrast head computed tomography (CT), or xanthochromia of cerebrospinal fluid confirmed by spectrophotometric analysis.\n* Eligible etiologies\u002Fpatterns:\n\n  * Aneurysmal SAH\n  * SAH from other intracranial vascular malformation (e.g. AVM, dural AVF)\n  * Perimesencephalic SAH\n  * Non-perimesencephalic angiogram negative SAH\n  * SAH from intracranial artery dissection\n\nExclusion Criteria:\n\n* Traumatic, neoplastic, infection related (except mycotic aneurysms), or iatrogenic SAH\n* Isolated convexity SAH","ALL",{"count":18,"type":19},1000,"ESTIMATED","18 Months","OBSERVATIONAL","The purpose of this registry is to collect detailed information on the characteristics, treatment, and outcomes of patients with a subarachnoid hemorrhage. This information will enable research aimed at improving the safety and effectiveness of current and future treatments. By studying these data, the investigators aim to identify which treatment strategies offer the best results and which factors are most important in the care of patients with a subarachnoid hemorrhage. The knowledge gained from this research will help improve patient care in the future.",[24],"Subarachnoid Hemorrhage, Spontaneous","RECRUITING","2026-03-15",{"date":28,"type":29},"2026-03-19","ACTUAL",{"date":31,"type":29},"2024-02-12",{"date":33,"type":19},"2028-02-01",{"name":35,"class":36},"UMC Utrecht","OTHER",9,{"id":39,"slug":40,"hasResults":11,"nctId":41,"briefTitle":42,"officialTitle":43,"acronym":44,"eligibilityCriteria":45,"healthyVolunteers":11,"sex":16,"minAge":46,"maxAge":4,"enrollmentInfo":47,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":49,"conditions":50,"keywords":4,"overallStatus":25,"whyStopped":4,"lastUpdateSubmitDate":52,"lastUpdatePostDateStruct":53,"startDateStruct":55,"completionDateStruct":57,"leadSponsor":59,"locationsCount":61},"100532887","hemodynamic-instability-of-patient-with-spontaneous-subarachnoid-hemorrhage-100532887","NCT06218654","Hemodynamic Instability of Patient With Spontaneous Subarachnoid Hemorrhage","Hemodynamic Instability of Patient With Spontaneous Subarachnoid Hemorrhage and Systemic Response to Endogenous Stress. Urinary and Serum Factors and Clinical Developments. Pilot Study Toward the Predictivity of Clinical Failure and Variation on Outcome in the Neurosurgical Patient (HISAHES)","HISAHES","Inclusion Criteria:\n\n* Patients with spontaneous subarachnoid hemorrhage, including those with perimesencephalic subarachnoid hemorrhage and aneurysmal subarachnoid hemorrhage.\n* Adult patients.\n* Confirmed presence of spontaneous subarachnoid hemorrhage through neuroimaging.\n* Obtained informed consent for specific study biomarkers\n\nExclusion Criteria:\n\n* Age \\\u003C18 years.\n* Post-traumatic subarachnoid hemorrhage.","18 Years",{"count":48,"type":19},90,"The goal of this observational study is to learn about the role of biomarkers in spontaneous subarachnoid hemorrhage (sSAH) as predictors of severity of clinical outcome. The test of biomarkers is based on regular blood and urinary samples. Blood levels of highly specific cardiac troponin (cTNI), natriuretic peptides (NT-ProBNP), S100 beta protein, neuron-specific enolase (NSE), glial fibrillary acidic protein (GFAP), ubiquitin carboxy-terminal hydrolase (UCH-L1), soluble Tumor Necrosis Factor Receptor-2 (sST2), and soluble urokinase plasminogen activator receptor (suPAR), as well as urinary levels of epinephrine and norepinephrine are the biomarkers explored. All adult participants with spontaneous subarachnoid hemorrhage are involved in the study.\n\nThe main questions aim to answer are:\n\n* which of these molecules can be prognostic for patients' outcome\n* which are the prognostic levels of these biomarkers to predict patients' outcome.\n\nParticipants will undergo blood and urinary samples during hospitalization at 24 hours, 72 hours and after 7 days.",[24,51],"Subarachnoid Hemorrhage, Aneurysmal","2024-04-10",{"date":54,"type":29},"2024-04-11",{"date":56,"type":29},"2024-01-15",{"date":58,"type":19},"2026-07-31",{"name":60,"class":36},"Fondazione Policlinico Universitario Agostino Gemelli IRCCS",1]