[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"subglottic-stenosis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:subglottic-stenosis":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,39,64],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":38},"100612838","rna-sequencing-of-discarded-tracheal-stenosis-tissue-to-characterize-cellular-and-molecular-pathogenesis-100612838",false,"NCT07258784","RNA Sequencing of Discarded Tracheal Stenosis Tissue to Characterize Cellular and Molecular Pathogenesis","Inclusion Criteria:\n\n* Patients with benign tracheal stenosis\n\nExclusion Criteria:\n\n* Malignancy. active infection","ALL","18 Years","80 Years",{"count":19,"type":20},10,"ESTIMATED","OBSERVATIONAL","Benign tracheal stenosis is a rare but potentially life-threatening condition, typically resulting from fibroinflammatory scarring. It can be secondary to iatrogenic etiologies such as intubation or tracheostomy , as well as autoimmune diseases and being idiopathic. Patients typically undergoes endoscopic or surgical interventions to open up the airways. This project will analyze resected or biopsied tissue from patients with benign tracheal stenosis to define disease-specific RNA expression profiles.",[24,25],"Tracheal Stenosis","Subglottic Stenosis","RECRUITING","2025-11-20",{"date":29,"type":30},"2025-12-02","ACTUAL",{"date":32,"type":30},"2025-09-11",{"date":34,"type":20},"2026-12-31",{"name":36,"class":37},"University of Maryland, Baltimore","OTHER",1,{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":43,"acronym":4,"eligibilityCriteria":44,"healthyVolunteers":11,"sex":15,"minAge":4,"maxAge":4,"enrollmentInfo":45,"targetDuration":4,"studyType":47,"phases":48,"briefSummary":50,"conditions":51,"keywords":52,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":38},"100586580","slide-tracheoplasty-versus-tracheal-resection-anastomosis-in-acquired-tracheal-stenosis-100586580","NCT06917222","Slide Tracheoplasty Versus Tracheal Resection Anastomosis in Acquired Tracheal Stenosis","Inclusion Criteria:\n\n* All patients with grade III, IV acquired tracheal stenosis (e.g., due to trauma, prolonged intubation) regardless their age or sex.\n\n  * Patient with symptomatic high grade II acquired laryngotracheal stenosis after failure of endoscopic interventions.\n  * Clinical indications for surgical intervention (Symptoms of airway obstruction).\n  * Feasible for surgical intervention.\n\nExclusion Criteria:\n\n* congenital tracheal stenosis\n\n  * Malignant stenosis.\n  * Severe comorbidities that contraindicate the surgery.\n  * Patients refusing to sign the consent.",{"count":46,"type":20},30,"INTERVENTIONAL",[49],"NA","Aim of the Work To compare the clinical outcomes between patients will undergo slide tracheoplasty and those will undergo tracheal resection anastomosis for acquired tracheal stenosis.",[24,25],[53,54],"Slide tracheoplasty","Tracheal resection anastomosis","2025-09-22",{"date":57,"type":30},"2025-09-25",{"date":59,"type":30},"2025-05-01",{"date":61,"type":20},"2026-08-01",{"name":63,"class":37},"Mansoura University Hospital",{"id":65,"slug":66,"hasResults":11,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":4,"eligibilityCriteria":70,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":71,"enrollmentInfo":72,"targetDuration":4,"studyType":47,"phases":74,"briefSummary":75,"conditions":76,"keywords":77,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":38},"100537241","endoscopic-mucosal-injection-versus-ultrasound-guided-injection-of-triamcinolone-to-treat-subglottic-stenosis-100537241","NCT06275269","Endoscopic Mucosal Injection Versus Ultrasound-Guided Injection of Triamcinolone to Treat Subglottic Stenosis","Comparison of the Safety and Economics of Translaryngeal Endoscopic Mucosal Injection Versus Ultrasound-Guided Injection of Triamcinolone for the Treatment of Subglottic Stenosis: a Multicenter, Randomized Controlled Study.","Inclusion Criteria:\n\n* 1: \"Diagnosed with subglottic stenosis through laryngoscopic examination or imaging studies such as CT.\"\n* 2: \"Experiencing symptoms related to subglottic stenosis, such as breathing difficulties, hoarseness, etc.\"\n\nExclusion Criteria:\n\n* 1: \"Severe cardiopulmonary dysfunction, patients extremely debilitated and unable to tolerate the procedure.\"\n* 2: \"Patients allergic to lidocaine, midazolam, triamcinolone, or any of their components.\"\n* 3: \"Pregnant or lactating women.\"\n* 4: \"Unstable angina, congestive heart failure, severe bronchial asthma.\"\n* 5: \"Severe hypertension and arrhythmias, hemodynamically unstable, and severe respiratory failure (PaO2 \\\u003C60mmHg after oxygen therapy or mechanical ventilation).\"\n* 6: \"Known coagulation dysfunction, inability to stop anticoagulants, antiplatelet agents, aspirin, or nonsteroidal anti-inflammatory drugs before treatment.\"\n* 7: \"Patients do not agree to participate in this study.\"\n* 8: \"Participation in other studies within the last three months and not withdrawn or concluded, or having received triamcinolone treatment less than 1 month ago.\"\n* 9: \"Researchers believe there are any circumstances making the patient unsuitable for inclusion.\"","65 Years",{"count":73,"type":20},40,[49],"This study employs a multicenter, randomized controlled trial method, where patients meeting the inclusion criteria for subglottic stenosis are randomly divided into two groups. These groups are respectively undergoing translaryngeal endoscopic mucosal injection and ultrasound-guided injection of triamcinolone treatment. The comparison will focus on various indicators such as therapeutic effect, incidence of adverse reactions, treatment costs, and hospital resource utilization between the two groups. The safety and effectiveness will be compared to determine the relative merits of the two treatment methods.",[25],[25,78,79,80],"Triamcinolone","Translaryngeal Endoscopic Mucosal Injection","Ultrasound-Guided Injection","2025-02-07",{"date":83,"type":30},"2025-02-10",{"date":85,"type":30},"2024-03-10",{"date":87,"type":20},"2025-12-31",{"name":89,"class":37},"China-Japan Friendship Hospital"]