[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"substance-use-recovery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:substance-use-recovery":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,65,102],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":31,"overallStatus":52,"whyStopped":4,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":64},"100614348","reducing-parental-substance-use-and-enhancing-family-resilience-among-rural-families-through-ohio-start-100614348",false,"NCT07278427","Reducing Parental Substance Use and Enhancing Family Resilience Among Rural Families Through Ohio START","Reducing Parental Substance Use, Improving Child Health Outcomes, and Enhancing Family Resilience Among Rural Families Through Ohio START (Sobriety, Treatment, and Reducing Trauma)","Ohio START","Inclusion Criteria:\n\n* age 18 or older;\n* currently enrolled in Ohio START;\n* are unemployed or have family income at or below the federal poverty level,\n* designated as the primary parent in the Ohio START case plan.","ALL","18 Years",{"count":20,"type":21},400,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn about the roles played by parental activity spaces and social networks in reducing parental substance use and promoting child and family health outcomes in the context of Ohio START (Sobriety, Treatment, and Reducing Trauma) for families in rural areas. This study will investigate if substance use treatment service referrals and family peer mentoring services provided by Ohio START lead to positive changes in parental activity spaces and social networks, and if these positive changes lead to better child and family outcomes. The main questions it aims to answer are:\n\n* Does having behavioral health services (referred by Ohio START workers) close to where parents spend their time help with substance use recovery and child health?\n* Does peer mentor support through Ohio START help parents build stronger social connections and family resilience, and does this lead to better long-term family health?\n* Do these associations differ in rural areas compared to urban areas?\n\nParticipants will:\n\n* Answer survey questions about their substance use, parenting, child health, and family well-being across three waves (Wave 1: when they enroll in the study, Wave 2: 6-month follow-up, and Wave 3: 12-month follow-up)\n* Share information about places they go regularly (such as work, stores, and healthcare visits)\n* Share information about people in their support network",[25,26,27,28,29,30],"Substance Use Disorder (SUD)","Rural Health","Family Resilience","Child Maltreatment","Child Well-beiing","Substance Use Recovery",[32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,15,48,49,50,51],"Substance use disorder","Child abuse and neglect","Rural health","Child welfare services","Low socioeconomic status","Rurality","Longitudinal study","Prospective study","Family resilience","Social network","Activity spaces","Child maltreatment","Parental substance use","Family peer mentors","Social networks","Rural families","Child well-being","Substance use treatment services","Family health","The START model","RECRUITING","2026-05-12",{"date":55,"type":56},"2026-05-14","ACTUAL",{"date":58,"type":56},"2026-04-27",{"date":60,"type":21},"2030-08-31",{"name":62,"class":63},"Ohio State University","OTHER",1,{"id":66,"slug":67,"hasResults":11,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":11,"sex":17,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":4,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":4,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":64},"100632971","evaluation-of-the-addpro-vocational-reintegration-program-add-pro-eval-100632971","NCT07520617","Evaluation of the ADD'Pro Vocational Reintegration Program (ADD-PRO-EVAL)","Evaluation of the ADD'Pro Program: A Partnership-Based Approach to Support Vocational Reintegration of Patients Receiving Addiction Care (ADD-PRO-EVAL)","ADD-PRO-EVAL","Inclusion Criteria:\n\n* Adult of working age (18 years or older)\n* Diagnosed substance use disorder receiving medical care\n* Unemployed or on sick leave with a vocational reorientation project\n* Motivated to work in the competitive labour market\n* Living in or wishing to work in the Puy-de-Dôme department (63), France\n* Legally authorised to work\n* Capable of providing written informed consent\n* Affiliated with a French social security scheme\n\nExclusion Criteria:\n\n* Medical care provided under a court-ordered treatment obligation\n* Previously included in the ADD'Pro program\n* Residing outside the Puy-de-Dôme with no plan to work in the department\n* Under legal guardianship (tutelle, curatelle, or sauvegarde de justice)\n* Deprived of liberty","16 Years","70 Years",{"count":76,"type":21},100,"INTERVENTIONAL",[79],"NA","The goal of this clinical trial is to evaluate whether an integrated medico-psychosocial vocational support program (ADD'Pro) can improve employment outcomes in adults with substance use disorders receiving care at a specialized addiction day hospital.\n\nThe main question it aims to answer is:\n\n\\- Does participation in the ADD'Pro program increase the rate of competitive employment (at least one day worked in the open labour market) at 6 months compared to standard employment services?\n\nResearchers will compare participants enrolled in the ADD'Pro program to participants referred to conventional employment services (France Travail or Cap Emploi) to see if structured, dual medico-psychosocial support leads to higher rates of vocational reintegration, better employment preparation, improved quality of life, and reduced physiological stress reactivity.\n\nParticipants will:\n\n* Be randomly assigned to either the ADD'Pro program or standard employment services\n* If assigned to ADD'Pro: receive immediate individualised support from a vocational counsellor (CIP) at the CeCler Association, running in parallel with their hospital addiction care, with no fixed end date\n* If assigned to standard care: be referred to conventional employment services with monthly follow-up interviews at the hospital, and the option to join ADD'Pro after 6 months\n* Complete structured interviews and validated questionnaires at inclusion, 3, 6, and 12 months\n* A sub-sample of up to 50 participants will additionally take part in a simulated job interview stress test (adapted TSST) with salivary biomarker collection and heart rate monitoring at inclusion and 6 months",[82,83,30,84,85,86,25,87,88,89,90,91],"Addiction","Addiction Disorders","Return to Work","Recovery","Recovery Outcomes","Employment, Supported","Employment","Substance Related Disorders","Vocational Rehabilitation","Substance Use (Drugs, Alcohol)","NOT_YET_RECRUITING","2026-04-02",{"date":95,"type":56},"2026-04-09",{"date":97,"type":21},"2026-04",{"date":99,"type":21},"2029-04",{"name":101,"class":63},"University Hospital, Clermont-Ferrand",{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":109,"targetDuration":4,"studyType":77,"phases":111,"briefSummary":112,"conditions":113,"keywords":123,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":130,"lastUpdatePostDateStruct":131,"startDateStruct":133,"completionDateStruct":135,"leadSponsor":137,"locationsCount":64},"100591839","khanya-ekhaya-a-home-based-intervention-100591839","NCT06985641","Khanya Ekhaya: A Home-Based Intervention","Home-Based Community Health Worker Support for Mental Health Among People Living With HIV in South Africa: A Hybrid Effectiveness Implementation Trial","Inclusion Criteria:\n\nCHWs:\n\n* at least 18 years old\n* must conduct home visits for people with HIV newly initiating or re-initiating ART at the approved clinic site\n\nPATIENTS:\n\n* at least 18 years old\n* seen by a CHW after newly initiating or re-initiating ART in the past three months\n* screen positive for depressive symptoms or harmful alcohol use\n\nExclusion Criteria:\n\nCHWs:\n\n-Unable or unwilling to complete informed consent and study procedures in English, isiXhosa, or Afrikaans\n\nPATIENTS:\n\n-Unable or unwilling to complete informed consent and study procedures in English, isiXhosa, or Afrikaans",{"count":110,"type":21},119,[79],"Mental health conditions, such as depression, anxiety, and harmful alcohol use are prevalent among people with chronic diseases, including HIV, and contribute to poor engagement in care. There is a need to address untreated mental health problems. Community health workers (CHWs) are frontline workers who play a central role in supporting vulnerable individuals to stay in care, including seeking people living with HIV who are newly initiating antiretroviral therapy (ART) or re-initiating after a period of care disengagement. CHW-delivered interventions are promising for improving engagement and retention in care. Yet, these programs rarely address mental health -a significant barrier to chronic disease care engagement and treatment. An approach that moves beyond providing care in the clinic setting is needed. Community-delivered home-based mental health care has been shown to be feasible and acceptable and shows promise for integration into broader community health care services for people with chronic conditions, such as HIV.",[114,115,116,117,118,119,120,121,122,30],"HIV","HIV Antiretroviral Therapy (ART) Adherence","Mental Health","Substance Use Disorders","Stigma","Community Health Workers","Training","Global Health","Mental Health Recovery",[119,124,121,30,122,114,125,126,127,128,129,117],"Health Personnel","Health Care Seeking Behavior","Treatment Adherence and Compliance","Attitude of Health Personnel","Substance Use Stigma","Mental health Stigma","2025-05-14",{"date":132,"type":56},"2025-05-22",{"date":134,"type":21},"2025-09-01",{"date":136,"type":21},"2026-06-15",{"name":138,"class":63},"University of Maryland, College Park"]