[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"substance-use-risk\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:substance-use-risk":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,45,78],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100533132","structural-racism-reward-related-decision-making-and-substance-use-risk-100533132",false,"NCT06221839","Structural Racism, Reward Related Decision Making and Substance Use Risk","Structural Racism, Neurocognition in Reward Related Decision Making and Substance Use Risk","Inclusion Criteria:\n\n1. The adolescent participant is a biological or non-biological child of a member of the original Boricua Youth Study (BYS) sample.\n2. The adolescent is between the ages of 11 to 14.5 at the time of recruitment, and 11 to \\\u003C15 at the time of study participation.\n3. If the parent\u002Fcaregiver is not an original BYS member, they have provided a consent to contact form.\n4. Parent\u002Fcaregiver is between the ages of 18-64.5 at the time of recruitment and 18 to \\\u003C65 at the time of study participation\n\nExclusion Criteria:\n\n1. Major neurological disorder (e.g. seizure disorder) or cognitive impairment (e.g., moderate to severe Autism Spectrum Disorder, Intellectual Disability)\n2. Exclusion criteria for the MRI scan only: MRI contraindications (e.g., irremovable metal on the body, pacemaker, braces, etc.; pregnancy (while required by NYSPI).",true,"ALL","11 Years","14 Years",{"count":21,"type":22},72,"ESTIMATED","OBSERVATIONAL","The goal of this observational study, which has a pilot phase (R61) and a second, larger phase (R33), is to learn about the impact of indicators of structural racism (SR) on substance use risk in Puerto Rican adolescents living in the mainland US and in Puerto Rico. To do this, we will look at how indicators of SR relate to brain structure, brain function during reward-related choices, belief in a just world, and substance use risk indicators in Puerto Rican adolescents living in the mainland US (mostly in New York) and in Puerto Rico (mostly in San Juan). We are currently focused on the R61 (pilot) phase. This pilot phase aims to answer the question: Is there a relationship between indicators of SR and brain structure, brain function during reward-related decision making, and belief in a just world? If we are able to establish a relationship between SR indicators and outcomes, we will continue to the second phase of the study at that time.\n\nWe will be collecting data from a total of 72 adolescents and their parents; n=36 in NY; n=36 in PR). Participation in the research study will include: 1. an interview with the parent or caregiver (approximately 2.5 hours) regarding the child's demographics, mental health symptoms, past experiences, the parent or caregiver's relationship with the child, as well as cultural values and acculturation; 2. an interview with the child (approximately 2.5 hours) regarding the child's past experiences, their current beliefs, personality traits and mental health symptoms; 3. an MRI scan for the child including task-based, structural and resting-state functional connectivity (approximately 1 hour).",[26,27],"Structural Racism","Substance Use Risk",[29,30,31],"Adolescent Behavior","Reward Related Decision Making","fMRI","RECRUITING","2026-02-18",{"date":35,"type":36},"2026-02-20","ACTUAL",{"date":38,"type":36},"2026-02-03",{"date":40,"type":22},"2027-07",{"name":42,"class":43},"Columbia University","OTHER",2,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":16,"sex":17,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":77},"100587002","protocol-study-on-addiction-trauma-and-immigration-among-vulnerable-young-adults-in-grand-est-100587002","NCT06922721","Protocol Study on Addiction, Trauma and Immigration Among Vulnerable Young Adults in Grand Est","ATICC: A Mixed-Methods Study on Addiction, Trauma, and Immigration Among Vulnerable Young Adults in the Grand Est Youth Network","ATICC","Inclusion Criteria:\n\n* Resident in a Housing center, speak and read french, adult participants who are not under guardianship or curatorship, any cultural background.\n\nExclusion Criteria:\n\n* minors, don't speak and read french, adults under guardianship and curatorship.","18 Years","25 Years",{"count":56,"type":22},182,"The ATICC study (Addiction, Trauma, and Immigration, Prevention and Cross-Cultural Support for Care) investigates the complex relationships between trauma, substance use, migration experiences, and mental health perceptions among vulnerable young adults in Transitional Housing (Foyers de Jeunes Travailleurs) in France. Using a tripartite methodology, the study includes: (1) a cross-sectional survey to identify risk factors, (2) qualitative interviews to explore individual experiences, and (3) a longitudinal intervention using focus groups to assess psychological well-being and attitudes toward care. The findings will contribute to developing culturally adapted prevention and support programs.",[59,60,27],"Trauma and Stress-related Disorders","Substance Use Disorder (SUD)",[62,63,64,65,66,67],"addiction","trauma","Immigration","Mental health","young adults","Substance use","2025-04-03",{"date":70,"type":36},"2025-04-10",{"date":72,"type":36},"2025-01-06",{"date":74,"type":22},"2025-12",{"name":76,"class":43},"University of Lorraine",7,{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":16,"sex":17,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":4,"studyType":90,"phases":91,"briefSummary":93,"conditions":94,"keywords":100,"overallStatus":104,"whyStopped":4,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":4},"100574072","options-for-navigating-talking-about-risk-and-adolescent-choices-100574072","NCT06754527","Options for Navigating Talking About Risk and Adolescent Choices","Emotion Regulation Intervention to Prevent Substance Use Among Youth in the Child Welfare System","ON-TRAC","Inclusion Criteria:\n\n* Contact with the Rhode Island child welfare system\n* Caregiver who is a parent\u002Fguardian of a child who experienced maltreatment\n* Caregiver who speaks English or Spanish\n* Caregiver who does not have developmental delays\n* Adolescent who is between 12-15 years of age\n* Adolescent who is fluent in English\n* Adolescent who has active follow-up with the Rhode Island child welfare system due to an indicated finding of abuse or neglect in the past year\n\nExclusion Criteria:\n\n* Adolescent who cannot read at a 4th grade level\n* Adolescent who has a sibling who has participated in the program\n* Adolescent who has developmental delays\n* Adolescent who lacks parental consent for the study","12 Years","15 Years",{"count":89,"type":22},200,"INTERVENTIONAL",[92],"NA","This study will examine the effectiveness of ON-TRAC (Options for Navigating Talking about Risk and Adolescent Choices), which is an online substance use prevention program that also teaches emotion regulation skills. 200 adolescents, 12-15 years of age, will be randomized to ON-TRAC or a wait list comparison group (who will be offered the intervention at the end of their study participation) to determine impact on substance use, emotion regulation abilities, mental health symptoms, and other risk behavior outcomes.",[95,27,96,97,98,99],"Substance Use (Drugs, Alcohol)","Substance Use","Emotion Regulation","Risk Reduction Behavior","Risk Reduction",[101,102,103],"adolescent substance use","emotion regulation","risk reduction","NOT_YET_RECRUITING","2024-12-30",{"date":107,"type":36},"2025-01-01",{"date":109,"type":22},"2026-03-01",{"date":111,"type":22},"2029-02-01",{"name":113,"class":43},"Rhode Island Hospital"]