[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"sudden-death\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:sudden-death":33},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":26,"conditions":27,"keywords":34,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100606394","phase-2-early-double-sequential-defibrillation-in-out-of-hospital-cardiac-arrest-100606394",false,"NCT07174986","Early Double Sequential Defibrillation in Out of Hospital Cardiac Arrest","\"A Randomized Trial Assessing the Effect of Early Double Sequential Defibrillation With Anterior-posterior and Anterior Lateral Pad Placement and Sequential Defibrillation Compared to Standard Pad Placement and Single Defibrillation in Patients With Out of Hospital Cardiac Arrest With Initial Shockable Rhythm and at Least One Failed Standard Defibrillation\"","DOUBLE D","Inclusion Criteria:\n\n* OHCA patients with VT\u002FVF at first rhythm analysis and at least one defibrillation performed in standard (A-L) position\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years\n* Obvious pregnancy\n* Known preexisting Do Not Attempt Resuscitation order","ALL","18 Years",{"count":20,"type":21},916,"ESTIMATED","INTERVENTIONAL",[24,25],"PHASE2","PHASE3","Some of the patients affected by Out-of-hospital cardiac arrest (OHCA) with ventricular fibrillation (VF)\u002Fventricular tachycardia (VT) do not respond to initial defibrillation. The survival decreases with number of defibrillations required to terminate VF\u002FVT. In 2022, one prospective cluster randomized trial showed increased survival among (OHCA) patients in refractory VF using Double Sequential Defibrillation (DSD). If DSD can increase survival among all patients in VF that dont respond to one defibrillation, i.e. before it has become refractory is not known.\n\nThe aim of this trial is to assess survival with a double defibrillation strategy initiated as soon as possible among patients with Out of Hospital Cardiac Arrest with initial shockable rhythm and at least one failed standard defibrillation, compared with continued resuscitation using standard defibrillation.",[28,29,30,31,32,33],"Out of Hospital Cardiac Arrest","Ventricular Fibrillation","Defibrillation","CPR","ACLS","Sudden Death",[35,36,32],"Double sequential defibrillation","Double sequential external defibrillation","RECRUITING","2026-02-12",{"date":40,"type":41},"2026-02-17","ACTUAL",{"date":43,"type":41},"2025-09-08",{"date":45,"type":21},"2029-12",{"name":47,"class":48},"Gabriel Riva","OTHER",14]