[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"suicidal\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:suicidal":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,56,79,105,133,167],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":34,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":44,"lastUpdatePostDateStruct":45,"startDateStruct":48,"completionDateStruct":50,"leadSponsor":52,"locationsCount":55},"100642005","reward-sensitivity-digital-intervention-for-suicide-risk-100642005",false,"NCT07661901","Reward Sensitivity Digital Intervention for Suicide Risk","Pilot Development of a Youth-Focused Digital Just-in-Time Adaptive Intervention to Enhance Reward Sensitivity and Reduce Suicidal Ideation","DIGIReward","Inclusion Criteria:\n\nADOLESCENTS\n\n* Aged 13-17 years old\n* Recent suicidal ideation\n* Access to a smartphone device\n* Residing in the Philadelphia metropolitan area\n\nLEGALGUARDIANS\n\n* They are the legal guardian of an adolescent that meets all study criteria (see above)\n* They can read, write, and speak English\n\nExclusion Criteria:\n\nADOLESCENTS\n\n* Psychotic disorder, including schizophrenia, schizoaffective disorder, or psychotic disorder not otherwise specified, with a past year psychotic episode prior to baseline\n* Bipolar disorder I diagnosis, with a past year manic episode prior to baseline\n* Imminent suicide risk (e.g., active suicidal ideation with a specific plan and intent)\n\nLEGALGUARDIANS\n\n\\- There are no exclusion criteria for legal guardians","ALL","13 Years","17 Years",{"count":21,"type":22},20,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to develop and test an app designed to reduce suicide risk and improve emotional well-being in adolescents. The study will test if the app's daily check ins and recommended mood boosting skills will improve the adolescent's overall mood and suicidality. The main question it aims to answer is:\n\n• Is the app practical and acceptable to use daily?\n\nIn the study, adolescents will:\n\n* Participate in a focus group with other adolescents and provide feedback on the app itself (design, ease of use, etc.).\n* Complete surveys and assessments on their mood, thoughts, and experiences.\n* Complete assessments about their app experience.\n\nIn the study, the legal guardian of the adolescent will:\n\n* Participate in a focus group with other adolescents and provide feedback on the app itself (design, ease of use, etc.).\n* Complete assessments about their app experience.",[28,29,30,31,32,33],"Suicidal Ideation","Suicidal","Suicidal Thoughts","Digital Health Intervention","Reward Sensitivity","Anhedonia",[35,36,37,38,39,40,41,42,32,33],"Adolescents","Legal Guardians","Digital","Philadelphia","Suicide","Intervention","Prevention","Dyads","RECRUITING","2026-06-16",{"date":46,"type":47},"2026-06-22","ACTUAL",{"date":49,"type":22},"2026-06",{"date":51,"type":22},"2027-09",{"name":53,"class":54},"University of Pennsylvania","OTHER",1,{"id":57,"slug":58,"hasResults":11,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":4,"eligibilityCriteria":62,"healthyVolunteers":11,"sex":17,"minAge":63,"maxAge":4,"enrollmentInfo":64,"targetDuration":4,"studyType":23,"phases":66,"briefSummary":68,"conditions":69,"keywords":4,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":55},"100626774","phase-1-testing-a-digital-mindfulness-program-to-support-people-experiencing-suicidal-thoughts-100626774","NCT07440004","Testing a Digital Mindfulness Program to Support People Experiencing Suicidal Thoughts","An Initial Feasibility and Acceptability Study of the Healthy Minds Program: A Digital Mindfulness-Based Intervention for Individuals Experiencing Suicidal Thoughts","Inclusion Criteria:\n\n* age 18 or older\n* past month history of active suicidal ideation\n* English speaking\n* primary owner of smartphone\n* has regular access to the internet\n* able to validate their identity with a valid form of legal ID (via driver's license, student ID, state-issued ID, etc.)\n* able to understand the nature of the study, provide informed consent, and complete study procedures\n\nExclusion Criteria:\n\n* unable to understand the study procedures\n* not fluent in English\n* being unable to verify their identity","18 Years",{"count":65,"type":22},50,[67],"PHASE1","The purpose of this clinical trial is to see whether the Healthy Minds Program (HMP) is practical to use, well-received, and shows early signs of helping people who have recently experienced suicidal thoughts or behaviors.\n\nParticipants will:\n\n* complete questionnaires\n* use HMP app for 4 weeks",[29],"2026-05-19",{"date":72,"type":47},"2026-05-22",{"date":74,"type":47},"2026-04-10",{"date":76,"type":22},"2026-12-15",{"name":78,"class":54},"University of Wisconsin, Madison",{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":17,"minAge":63,"maxAge":86,"enrollmentInfo":87,"targetDuration":4,"studyType":23,"phases":89,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":95,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":55},"100563344","improving-coping-to-reduce-suicide-risk-following-ed-discharge-100563344","NCT06614946","Improving Coping to Reduce Suicide Risk Following ED Discharge","Facilitating Effective Coping to Reduce Suicide Risk Following ED Discharge: A Micro-randomized Trial to Develop an Adaptive Text-based Intervention","Inclusion Criteria:\n\nIndividuals presenting to an ED with either:\n\n1. actual, interrupted, or aborted attempt in the last 4 weeks\n2. suicidal ideation within the last week\n\nExclusion Criteria:\n\n* Severe cognitive impairment or altered mental status (psychosis, manic state)\n* Severe aggression\u002Fagitation,\n* Being admitted or transferred into inpatient care,\n* Patient not owning a cell phone with text messaging capability","65 Years",{"count":88,"type":22},120,[25],"The researchers hope to learn whether an electronic safety plan (ESP) and a supportive text messaging program are feasible and acceptable to adult patients with recent suicidal thoughts or behavior after emergency department (ED) discharge. From this study, the researchers also hope to learn how to best carry out the ESP and text messaging program to improve outcomes for patients after ED discharge.",[29,92,28],"Suicide, Attempted",[94],"Emergency Department","NOT_YET_RECRUITING","2026-03-30",{"date":98,"type":47},"2026-03-31",{"date":100,"type":22},"2026-05",{"date":102,"type":22},"2027-02",{"name":104,"class":54},"University of Michigan",{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":111,"eligibilityCriteria":112,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":113,"enrollmentInfo":114,"targetDuration":4,"studyType":23,"phases":116,"briefSummary":118,"conditions":119,"keywords":121,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":132},"100462622","phase-2-safe-treatment-for-emergency-presentation-for-suicidal-ideation-and-behavior-in-youth-100462622","NCT05304065","Safe Treatment for Emergency Presentation for Suicidal Ideation and Behavior in Youth","Youth Partners in Care for Suicide Prevention","SAFE STEPS","Inclusion Criteria:\n\n* age 13-24;\n* past-week suicidal behavior or ideation with plan or intent\n\nExclusion Criteria:\n\n* symptoms or illness that precludes informed consent or engagement in study procedures (e.g., active psychosis; drug dependence, no locator information);\n* youth not fluent in English\n* parent not fluent in English or Spanish.","24 Years",{"count":115,"type":22},1600,[117],"PHASE2","This randomized comparative effectiveness trial will compare two evidence-based approaches to emergency care for youth ages 13-24 who present to the Emergency Department (ED) with suicidal ideation or behavior. Outcomes will be monitored at baseline and at 3, 6 \\& 12 month follow-up assessments.",[39,29,120],"Self-Harm",[122],"self-harm","2025-12-24",{"date":125,"type":47},"2025-12-31",{"date":127,"type":47},"2022-10-17",{"date":129,"type":22},"2026-12-31",{"name":131,"class":54},"University of California, Los Angeles",5,{"id":134,"slug":135,"hasResults":11,"nctId":136,"briefTitle":137,"officialTitle":138,"acronym":4,"eligibilityCriteria":139,"healthyVolunteers":140,"sex":17,"minAge":18,"maxAge":141,"enrollmentInfo":142,"targetDuration":4,"studyType":144,"phases":4,"briefSummary":145,"conditions":146,"keywords":148,"overallStatus":95,"whyStopped":4,"lastUpdateSubmitDate":158,"lastUpdatePostDateStruct":159,"startDateStruct":161,"completionDateStruct":163,"leadSponsor":165,"locationsCount":4},"100590344","co-producing-lgbtq-affirmative-dbt-protocols-100590344","NCT06966193","Co-Producing LGBTQ-Affirmative DBT Protocols.","Co-Producing LGBTQ-Affirmative Intervention Protocols for LGBTQ+ People at Risk of Self-Harm and Suicide: A Co-Production Study","DBT Cohort Young Person Sample 1\n\nInclusion criteria will include that the young person:\n\n1. Is aged 13 to 21 years old;\n2. has completed at least four months of comprehensive DBT (i.e. inclusive of all four modes of intervention; Linehan, 1993; Miller et al., 2006; Rathus \\& Miller, 2015) in the past 24 months or have completed at least four months of DBT and are still in a comprehensive DBT programme;\n3. identifies as LGBTQ+ (including those questioning or unsure about their orientation\u002Fidentity);\n4. is willing and able to participate in the study. While no specific inclusion or exclusion criteria will be placed on other variables, typically to be eligible for a DBT programme, young people would need to have a history of self-harm and\u002For suicidal behaviours, difficulties with emotion regulation, and potentially difficulties with the remaining symptom list within borderline\u002Femotionally unstable personality disorder. Recruitment size is based on PPI recommendations regarding effective group sizes, with allowances for sample attrition.\n\nNon-DBT Cohort Young Person Sample 2\n\nInclusion criteria will follow similar to sample 1. The young person:\n\n1. Is aged 13 to 21 years old;\n2. has not accessed and is not currently enrolled in a comprehensive DBT programme;\n3. has experienced difficulties with LGBTQ-related identity confusion, managing stigma experiences, and connecting with similar others;\n4. identifies as LGBTQ+ (including those questioning or unsure about their orientation\u002Fidentity);\n5. is willing and able to participate in the study (i.e. are based in the UK and can attend the in-person and online groups).\n\nNo other inclusion or exclusion criteria will be systematically implemented for this group.\n\nDBT Therapist Sample\n\nInclusion criteria:\n\n1. Currently practicing or having completed (or recently finished, within the past 12 months) a comprehensive DBT programme as a DBT therapist. In order to practice as a DBT therapist, they must hold a professional qualification recognised by appropriate healthcare regulators.\n2. Having experience working with at least one LGBTQ+ client in DBT, who was aged between 13 and 21 years at the time.\n3. Being willing and able to participate in the study.",true,"21 Years",{"count":143,"type":22},32,"OBSERVATIONAL","Aims:\n\n1. To co-produce new intervention parts that meet the needs of LGBTQ+ people at risk of self-harm or suicidal thoughts, with LGBTQ+ people and DBT therapists. These intervention parts will be integrated into a Dialectical Behaviour Therapy (DBT) intervention, that is provided earlier in a persons mental health care journey, than DBT is usually targeted at.\n2. To assess how acceptable and feasible the co-production process was for participants, and how well it achieved co-production principles (e.g. participants feel supported, that the aims were transparent, etc).\n\nWhy is This Important? Young people who identify as lesbian, gay, bisexual, transgender, queer, and with other minoritised gender and sexual identities (LGBTQ+) are much more likely to self-harm and experience suicidal thoughts than cisgender-heterosexual (non-LGBTQ+) people. They also experience barriers when accessing mental health support. Some of these barriers come from a lack of support tailored towards their needs as an LGBTQ+ person. This often means that things get worse before they access the right support, and so are often seen in higher-intensity interventions (tier 4 or tertiary care), like DBT.\n\nWhat The Investigators Plan to Do:\n\nThe investigators plan to hold some focus groups with three different groups of people to co-produce the new intervention parts. The three groups include:\n\n1. A group of LGBTQ+ young people (13-21 years old) who have completed a at full DBT programme recently.\n2. A group of LGBTQ+ young people (13-21 years old) who have never been in a full DBT programme but experienced similar difficulties.\n3. A group of DBT therapists who have supported LGBTQ+ young people before.\n\nThe investigators will seek feedback from participants about how acceptable they found the study (e.g. how satisfied they were with the process), how feasible it was (e.g. were they able to attend and was it practice?), and how well they stuck to the coproduction principles (e.g. how supported they felt).",[120,29,147],"Emotional Dysregulation",[149,150,120,151,152,153,154,155,156,35,157],"LGBTQ+","DBT","Suicidal Behaviours","Emotion Dysregulation","Young People","Sexual Minorities","Gender Minorities","Co-Production","Therapists","2025-05-12",{"date":160,"type":47},"2025-05-15",{"date":162,"type":22},"2025-10-01",{"date":164,"type":22},"2026-07-30",{"name":166,"class":54},"King's College London",{"id":168,"slug":169,"hasResults":11,"nctId":170,"briefTitle":171,"officialTitle":172,"acronym":173,"eligibilityCriteria":174,"healthyVolunteers":11,"sex":17,"minAge":175,"maxAge":176,"enrollmentInfo":177,"targetDuration":4,"studyType":144,"phases":4,"briefSummary":179,"conditions":180,"keywords":183,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":186,"lastUpdatePostDateStruct":187,"startDateStruct":189,"completionDateStruct":191,"leadSponsor":193,"locationsCount":55},"100493655","eco-anxiety-and-suicide-100493655","NCT05707975","Eco-anxiety and Suicide","Eco-anxiety and Severity of Suicide Risk in Adolescents","EcoAnx","Inclusion Criteria:\n\n\\- Adolescents aged 12 to 16, hospitalized at the Hopital Femme Mère Enfant, in the child and adolescent psychopathology department\n\nExclusion Criteria:\n\n* Patient who does not speak French\n* Patient unable to read or write.\n* Patient with an intellectual development or oral comprehension disorder (eg severe dysphasia preventing understanding of the explanations given, or severe dyslexia preventing the reading of scale items).\n* Oral or written refusal by the parents or the child.\n* Child not affiliated to a social security system and under legal protection","12 Years","16 Years",{"count":178,"type":22},261,"Suicide is a major public health problem. About 9,000 suicides per year are retrieved by year in France. Between 15,000 and 20,0000 suicide attempts give rise to contact with the healthcare system.\n\nAmong young people aged 15 to 24 years old, suicide is the second main cause of death. In this way, suicide among adolescents is a major public health priority, due to its seriousness, its frequency, and its potentially preventable nature.\n\nThe severity of suicide risk can be assessed by different scales, and the Columbia-Suicide Severity Rating Scale (C-SSRS) is the most widely used in the international literature for adolescents, assessing four dimensions: suicidal ideation, severity of ideation, suicidal behavior and lethality. The measurement of the seriousness of the suicide risk is therefore defined as the measurement of the importance of the direct and indirect negative consequences associated with this risk. It can be catch up in the four factors mentioned above.\n\nAnxiety is one of the central pillars influencing the suicidal risk of adolescents. Very few studies have identified operationalizable and generalizable risk factors for anxiety. However, in adolescents, one of the risk factors for anxiety seems particularly important, because it is a factor that is both generic (i.e., it can be found in different profiles of adolescents), related to the projection in the future (which characterizes this population), and relatively specific to this age group, while being operational through validated questionnaires. This important risk factor is the eco-anxiety, which corresponds to anxiety related to climate change.\n\nThe theme of climate change is certainly a central social issue, but also an important public health issue. First, climate change raises direct risks to human health, and indirectly some risks for mental health. For instance, the direct consequences of a drought or natural disaster can cause material hardship that impacts indirectly mental health (Thoma et al., 2021). Secondly, climate change can also raise direct risk for mental health, and especially the eco-anxiety which is not the consequence of a direct risk from the environment on an individual, but rather constitutes mental distress related to the fear of such changes.\n\nEco-anxiety can be identified and measured in a valid and reliable way thanks to a scale used in the international literature, the \"Climate Anxiety Scale\" (CAS), which was validated in 2020 with 22 items with 4 factors by Clayton and Karazsia (Clayton and Karazsia, 2020), and translated and validated in French in 2022 by Mouguiama-Daouda (Mouguiama-Daouda et al., 2022), retaining as the most appropriate model the version with the first 13 items. This scale is suitable for adolescents from the age of 12 years old.\n\nThis 13-item scale is composed of two subscales that assess cognitive and emotional difficulties in response to climate change and functional impairment. Two subscales are added to this 13-item scale (and thus are part of the 22-item CAS also validated), which assess 1) direct or indirect personal experience of climate change, and 2) behavioral commitment and the tendency to deploy adaptive behavioral responses to climate change.\n\nThe literature reports a correlation between eco-anxiety and depression (Mouguiama-Daouda et al., 2022). Indeed, depressive symptoms can influence how people worry about climate change. The correlation between eco-anxiety and anxiety is variable in the literature and has been studied using questionnaires focusing on generalized anxiety (Mouguiama-Daouda et al., 2022). Higher suicide rates have certainly been shown in populations affected by climate change (Dumont et al., 2020), related to the direct consequences of climate change, e.g., due to pollution, increased temperature or drought.\n\nHowever, to the knowledge of the investigators and despite the major public health impact in adolescents, no study has investigated the relationships between eco-anxiety and the severity of suicide risk.\n\nThis study therefore seeks to examine the association between eco-anxiety in adolescents, assessed using the French version of the CAS, and the severity of suicide risk, assessed using the French version of the C-SSRS. We hypothesize that there would be a relationship between eco-anxiety and the severity of suicide risk in adolescents. Such results would allow both to refine the understanding of the risk of suicide, in its relationship with a central theme of society and public health, and to better identify and prevent behaviors at risk of suicide among adolescents.",[39,181,29,182],"Suicide Attempt","Anxiety",[184,185,35],"Suicide risk","Eco-Anxiety","2025-01-03",{"date":188,"type":47},"2025-01-06",{"date":190,"type":47},"2023-04-27",{"date":192,"type":22},"2026-11-27",{"name":194,"class":54},"Hospices Civils de Lyon"]