[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"suicide-attempt\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:suicide-attempt":27},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,31,0,25,[9,45,77,105,139,162,189,209,230,242,270,297,319,344,372,411,438,464,489,517,540,567,590,620,643],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100054164","a-randomized-controlled-trial-of-a-smartphone-delivered-treatment-for-suicidal-thoughts-and-behavior-100054164",false,"NCT06686901","A Randomized Controlled Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior","Inclusion Criteria:\n\n* Adults ages 18+\n* Relatively frequent and recent (≥5 days within the past-month) active suicidal thoughts as assessed via SITBI-R.\n* Willing and able to provide at least one emergency contact (name, phone number, relation).\n* Owns an Android or iOS smartphone.\n* Possesses at least occasional access to Wi-Fi-enabled internet for data down\u002Fuploads.\n* Fluent in English and willing to provide informed consent.\n* Living in the Boston metropolitan area (i.e., \\~50 mile radius around Boston, MA)\n\nExclusion Criteria:\n\n* Recent (past 3-month) hypo\u002Fmanic symptoms or homicidal ideation or lifetime psychosis spectrum diagnosis as assessed via MINI 7.0.2.\n* Recent acute suicide risk operationalized as affirmative responses to BOTH below items during structured clinical interview AND evaluation by the PI in consultation with Mentors\u002FAdvisor Drs. Wilhelm, Kleiman, and\u002For Bentley:\n* At any time in past week: ≥ 8\u002F10 current intent to act on suicidal thoughts (0 \\[\"not at all\"\\] to 10 \\[\"extremely strong\"\\]); AND\n* At any time in past week: thought of a specific suicide plan (i.e, known method\u002Fmeans and\u002For location) with access to lethal means\n* Impaired vision (e.g., legal blindness), technological illiteracy, or intellectual disability that might impair ability to provide valid data and\u002For informed consent.","ALL","18 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study aims to evaluate the acceptability, safety, and efficacy of a smartphone-delivered intervention called Therapeutic Evaluative Conditioning for Suicide (TEC-S) in reducing suicidal thoughts and behaviors (STB) among adults with recent and frequent suicide ideation.",[26,27],"Suicidal Ideation","Suicide Attempt",[29,30,31],"Suicide","ecological momentary assessment (EMA)","Therapeutic Evaluative Conditioning (TEC)","NOT_YET_RECRUITING","2026-07-10",{"date":35,"type":36},"2026-07-13","ACTUAL",{"date":38,"type":20},"2027-01-30",{"date":40,"type":20},"2029-08-31",{"name":42,"class":43},"Massachusetts General Hospital","OTHER",1,{"id":46,"slug":47,"hasResults":12,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":21,"phases":55,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":44},"100596878","recovery-through-inspiration-support-and-empowerment-100596878","NCT07051200","Recovery Through Inspiration, Support, and Empowerment","RISE","Inclusion Criteria:\n\n* Chief complaint of suicidal ideation, suicide attempt, depression, and\u002For anxiety\n* discharged from inpatient care or from emergency department\n* men and women ages 18-27\n\nExclusion Criteria:\n\n* primary diagnosis of: substance use disorder, schizophrenia spectrum, intellectual development disorder, autism spectrum disorder (level II or III)","27 Years",{"count":54,"type":20},40,[23],"The goal of this pilot study is to test the effectiveness of a novel intervention for young adults (ages 18-27) with mental health conditions who have been released from an acute care psychiatric facility. The intervention aims to reduce suicidality, depression, anxiety, re-hospitalization, and improve mental health recovery by using outpatient services.\n\nThe current standard of care (SOC) for these patients at discharge includes a discharge plan with a list of their medications, anticipated outpatient appointments, and information on when and where to find community resources.\n\nThe intervention being tested involves the implementation of a mental health recovery education and support program, involving one-on-one and small group meetings led by Peer Support Specialists (PSS) and Recovery Community Organizations (RCO).\n\nParticipants will be assigned to either Cohort A or B for 8 weeks.\n\nCohort A will be the intervention group with PSS and RCOs.\n\n* Weeks 1-4: One-on-one meetings with PSS for education and support. Assessments will be completed at weeks 2 and 4.\n* Weeks 5 and 7: One-on-one meetings with PSS for education and support.\n* Week 6 and 8: Group meetings with PSS and other participants from RCOs. Assessments will be completed during these weeks.\n\nCohort B will be the SOC group with no PSS or RCOs.\n\n* Weeks 1-4: Weekly check in phone calls with a member of the research team. Assessments will be completed at weeks 2 and 4.\n* Weeks 5-8: Check in phone calls with a member of the research team every other week. Assessments will be completed at weeks 6 and 8.\n\nData collected from participant assessments, adherence to medication, and re-admittance to a psychiatric facility will be used to compare the intervention to the SOC.",[26,27,58,59],"Anxiety","Depression Disorders",[61,62,63,64,65,66],"Peer Support Specialist (PSS)","Recovery Community Organization (RCO)","Mental Health Recovery","Transitional Age Youth (TAY)","UT Southwestern Medical Center","Young Adult","RECRUITING","2026-06-22",{"date":70,"type":36},"2026-06-25",{"date":72,"type":36},"2025-04-01",{"date":74,"type":20},"2027-12-01",{"name":76,"class":43},"University of Texas Southwestern Medical Center",{"id":78,"slug":79,"hasResults":12,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":84,"targetDuration":4,"studyType":21,"phases":86,"briefSummary":87,"conditions":88,"keywords":89,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":102,"locationsCount":44},"100624065","evaluation-of-a-telehealth-case-management-intervention-to-prevent-suicide-among-soldiers-discharged-from-psychiatric-hospitalization-100624065","NCT07404787","Evaluation of a Telehealth Case Management Intervention to Prevent Suicide Among Soldiers Discharged From Psychiatric Hospitalization","SAFEGUARD Phase 2 Pathfinding Study","Inclusion Criteria:\n\n* Active duty Regular Army soldiers recently discharged from inpatient psychiatric care at a military treatment facility in the US\n* Access to telephone and computer (including smartphone)\n\nExclusion Criteria:\n\n* Impaired ability to provide informed consent\n* Terminal illness\n* Failure to complete baseline survey within 30 days of discharge\n* Positive screen for post-discharge suicide-related behaviors",{"count":85,"type":20},1500,[23],"This study evaluates the effectiveness of Pathfinding, a 6-month, remotely-delivered case management intervention designed to decrease suicidal behavior among active-duty Regular Army soldiers recently discharged from inpatient psychiatric treatment. Soldiers discharged from military treatment facilities across the U.S. will be identified and recruited to participate. Those who consent will be randomly assigned to receive either Treatment As Usual (TAU), which is the Army's standard post-discharge care, or TAU plus Pathfinding. Participants will complete a baseline assessment and follow-up assessments 6 months and 12 months later. The 6- and 12-month follow-up periods will also include examination of participants' electronic healthcare data and Army administrative data. The overall goals of the study are: (1) to evaluate whether Pathfinding decreases suicidal behaviors among soldiers transitioning from psychiatric hospitalization back to the community; and (2) to determine which discharged soldiers are most likely to benefit from the Pathfinding intervention versus TAU alone.",[29,27],[90,91,92,93,94,95],"suicide","suicide attempt","hospital discharge","military","intervention","case management","2026-06-08",{"date":98,"type":36},"2026-06-11",{"date":100,"type":36},"2026-02-24",{"date":40,"type":20},{"name":103,"class":104},"Uniformed Services University of the Health Sciences","FED",{"id":106,"slug":107,"hasResults":12,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":4,"eligibilityCriteria":111,"healthyVolunteers":12,"sex":16,"minAge":112,"maxAge":113,"enrollmentInfo":114,"targetDuration":4,"studyType":21,"phases":116,"briefSummary":117,"conditions":118,"keywords":122,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":130,"lastUpdatePostDateStruct":131,"startDateStruct":133,"completionDateStruct":135,"leadSponsor":137,"locationsCount":44},"100640620","youth-suicide-prevention-cams-bi-vs-safety-planning-in-a-randomized-trial-100640620","NCT07628192","Youth Suicide Prevention: CAMS-BI vs. Safety Planning in a Randomized Trial","Innovating Suicide Preventative Care for Youth; A Randomized Trial of CAMS- BI Versus Stanley- Brown Safety Planning Intervention in Preventing Suicide Driven Readmission","Inclusion Criteria:\n\n* Adolescents aged 12-17 years.\n* Admitted to inpatient psychiatry for suicide attempt or active suicidal ideation.\n* English-speaking patient and parent\u002Fguardian.\n* Ability to understand and the willingness to sign a written informed assent document with a parent\u002Fguardian willing and able to sign a written informed consent.\n\nExclusion Criteria:\n\n* Moderate or severe intellectual disability (IQ less than 70 and those patients in special education classes full time).\n* Schizophrenia or history of any type of psychosis including mood related psychosis and brief reactive psychosis.\n* In custody of Children's Services.","12 Years","17 Years",{"count":115,"type":20},118,[23],"This study outlines a randomized controlled trial evaluating two brief suicide-specific interventions for adolescents aged 12-17 who are hospitalized for suicidal ideation or attempts. Suicide remains a leading cause of death among youth, and many adolescents are discharged from inpatient care without targeted, suicide-focused treatment, contributing to high rates of readmission and ongoing risk. This study seeks to address that gap by comparing the effectiveness of the Collaborative Assessment and Management of Suicidality-Brief Intervention (CAMS-BI) with the Stanley-Brown Safety Planning Intervention (SPI), both delivered as single-session interventions during inpatient hospitalization.\n\nParticipants (N=118) will be randomly assigned to receive either CAMS-BI or SPI. CAMS-BI is a therapeutic, collaborative framework that focuses on identifying and addressing the underlying psychological drivers of suicidality, while SPI is a structured, practical approach that emphasizes immediate safety through coping strategies, support systems, and means restriction. Following the intervention, participants will be monitored for 90 days post-discharge, with follow-ups at 30, 60, and 90 days.\n\nThe primary outcome is the rate of psychiatric readmissions and suicide-related emergency department visits within 90 days of discharge. Secondary outcomes include changes in suicidal ideation, measured by the Beck Scale for Suicide Ideation, and caregiver confidence in managing their child's safety. Additional measures include distress levels, hopelessness, treatment satisfaction, and engagement.\n\nThe study hypothesizes that CAMS-BI will result in lower readmission rates, greater reductions in suicidal ideation, and improved caregiver confidence compared to SPI. Both interventions produce individualized safety or stabilization plans that are shared with patients and caregivers and incorporated into discharge planning to support continuity of care.\n\nSafety protocols are emphasized throughout the study, given the high-risk population. Participants receive standard clinical care, crisis resources, and close monitoring, with procedures in place to address any escalation in suicide risk. Data will be collected using secure systems, and confidentiality will be maintained through de-identification and controlled access.\n\nOverall, this study aims to determine whether a rapid, inpatient, suicide-focused intervention can improve short-term outcomes for high-risk youth and reduce the likelihood of rehospitalization, ultimately informing scalable approaches to suicide prevention in clinical settings.",[26,27,119,120,121],"Safety Plan","Depression \u002F Major Depressive Disorder","Hopelessness",[123,124,125,126,127,128,129,121],"Youth suicide","Suicide ideation","Suicide attempt","Suicidal behavior","Depression","CAMS therapy","Safety plan","2026-06-03",{"date":132,"type":36},"2026-06-04",{"date":134,"type":20},"2026-08-01",{"date":136,"type":20},"2027-03-01",{"name":138,"class":43},"The Cleveland Clinic",{"id":140,"slug":141,"hasResults":12,"nctId":142,"briefTitle":143,"officialTitle":144,"acronym":4,"eligibilityCriteria":145,"healthyVolunteers":12,"sex":16,"minAge":146,"maxAge":113,"enrollmentInfo":147,"targetDuration":4,"studyType":21,"phases":149,"briefSummary":150,"conditions":151,"keywords":152,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":157,"completionDateStruct":159,"leadSponsor":161,"locationsCount":44},"100622445","nudging-parental-actions-for-youth-suicide-prevention-100622445","NCT07383714","Nudging Parental Actions for Youth Suicide Prevention","Nudging Parental Action With A Randomized Controlled Trial of Text Messaging Intervention for Suicide Prevention","Inclusion Criteria:\n\n* Guardian must be able and willing to provide informed consent, and the participant must be able and willing to provide assent.\n* Parent and adolescent willingness and ability to participate in study procedures and complete assessments at baseline, 6 weeks, and 12 weeks.\n* Presentation to the ED for a suicide-related emergency, defined as suicidal ideation within the last 2 weeks or a suicide attempt within the past month.\n* Adolescents aged 12-17 years during the consent.\n* Access to a mobile phone with text messaging capability for the parent\u002Flegal guardian.\n* Ability to communicate in English.\n\nExclusion Criteria:\n\n* Absence of a legal guardian capable of providing consent.\n* Parents\u002Flegal guardians without access to a mobile phone with texting capability.\n* Inability to communicate in English.\n* Adolescents in state custody or under legal restrictions that prevent study participation.\n* Adolescents involved in the justice system in a manner that would interfere with study participation.\n* Adolescents with autism spectrum disorder or intellectual development disorder needing substantial or very substantial support","13 Years",{"count":148,"type":20},129,[23],"The goal of the study is to determine effectiveness of a behaviorally informed text messaging intervention to help parents increase safety practices and reduce their teens' access to lethal means following a suicide-related emergency department visit.",[29,27],[90,153,154],"digital health","lethal means restriction","2026-06-01",{"date":130,"type":36},{"date":158,"type":20},"2026-06-15",{"date":160,"type":20},"2027-08-31",{"name":76,"class":43},{"id":163,"slug":164,"hasResults":12,"nctId":165,"briefTitle":166,"officialTitle":167,"acronym":4,"eligibilityCriteria":168,"healthyVolunteers":169,"sex":16,"minAge":170,"maxAge":171,"enrollmentInfo":172,"targetDuration":4,"studyType":21,"phases":173,"briefSummary":174,"conditions":175,"keywords":178,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":181,"lastUpdatePostDateStruct":182,"startDateStruct":184,"completionDateStruct":186,"leadSponsor":188,"locationsCount":44},"100636620","neural-correlates-of-suicidal-behavior-in-youth-100636620","NCT07568054","Neural Correlates of Suicidal Behavior in Youth","Neural Correlates of Suicidal Behavior in Youth: a Pre and Post CAMS Therapy Neuroimaging Study","Inclusion Criteria:\n\n* Subjects must be 14-24 years old\n* Subjects must be:\n\n  * High Risk Subjects: Psychiatrically admitted due to a suicide attempt or history of 2 previous suicide attempts\n  * Medium Risk Subjects: Suicide ideation for the past year with no suicide attempt\n  * Minimal Risk Subjects: No previous history of suicidal ideation or behavior, not taking any psychiatric history or medication, and no family history of suicide\n* Subjects must have the ability to understand and the willingness to sign a written informed consent\u002Fassent document\n* Subjects must be English speaking\n\nExclusion Criteria:\n\n* Subjects with known history of Autism Spectrum Disorder; non-verbal patients\n* Subjects with moderate or severe intellectual disability (IQ less than 70 and those patients in special education classes full time)\n* Subjects with Schizophrenia or history of any type of psychosis including mood related psychosis and brief reactive psychosis\n* Within 6 months before initial screening, urine toxicology positive for phencyclidine, cocaine or amphetamines (subjects prescribed amphetamines for the management of ADHD will not be excluded)\n* Subjects with a history of moderate or severe substance or alcohol use per DSM-5 criteria in the past 6 months\n* Subjects who are currently pregnant or breastfeeding\n* Subjects in custody of Children's Services\n* Subjects with recent bone, tendon, spine or joint surgery\n* Subjects with recent metallic dental implants\n* Subjects weighing less than 30 kg or more than 200 kg",true,"14 Years","24 Years",{"count":19,"type":20},[23],"This study, titled \"Neural Correlates of Suicidal Behavior in Youth: a Pre and Post CAMS Therapy Neuroimaging Study,\" aims to better understand the brain mechanisms underlying suicidal thoughts and behaviors in adolescents and young adults (ages 14-24). Suicide is a leading cause of death in this population, and current clinical approaches often fail to accurately predict or prevent suicidal behavior. This study seeks to identify objective neurobiological markers associated with suicide risk and treatment response.\n\nParticipants will be divided into three groups: (1) high-risk individuals recently hospitalized following a suicide attempt, (2) medium-risk individuals with chronic suicidal ideation but no attempts, and (3) low-risk healthy controls. All participants will undergo advanced neuroimaging, including magnetoencephalography (MEG) and magnetic resonance imaging (MRI), along with comprehensive psychiatric assessments.\n\nThe study focuses on brain regions and networks implicated in suicidality, including the anterior cingulate cortex and salience network, as well as neurochemical markers such as glutamate. It also examines electrophysiological activity and functional connectivity patterns associated with suicidal thoughts and behaviors.\n\nHigh-risk participants will receive an evidence-based psychotherapy called the Collaborative Assessment and Management of Suicidality (CAMS). This therapeutic approach emphasizes collaboration between patient and clinician to identify and address the underlying drivers of suicidal thoughts, with a focus on increasing hope and reducing psychological distress. Neuroimaging and clinical assessments will be repeated after completion of CAMS to evaluate treatment-related changes.\n\nThe study's primary goals are to:\n\n* Identify neural and electrophysiological correlates of suicide risk.\n* Distinguish biological differences between individuals with suicidal ideation and those who have attempted suicide.\n* Determine how CAMS therapy affects brain function and neurochemistry.\n\nBy integrating clinical and neurobiological data, this research aims to improve understanding of suicidality, enhance risk prediction, and inform more effective, personalized interventions for at-risk youth.",[26,27,176,120,121,177],"Suicidal Behavior","Neurobiological",[179,125,126,123,127,121,128,180],"Suicidal ideation","Neuroimaging","2026-04-29",{"date":183,"type":36},"2026-05-05",{"date":185,"type":20},"2026-04-13",{"date":187,"type":20},"2031-10-01",{"name":138,"class":43},{"id":190,"slug":191,"hasResults":12,"nctId":192,"briefTitle":193,"officialTitle":193,"acronym":194,"eligibilityCriteria":195,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":196,"targetDuration":4,"studyType":21,"phases":198,"briefSummary":199,"conditions":200,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":201,"lastUpdatePostDateStruct":202,"startDateStruct":203,"completionDateStruct":205,"leadSponsor":207,"locationsCount":4},"100636607","brief-cognitive-behaviour-therapy-to-prevent-suicide-reattempts-a-feasibility-study-in-swedish-psychiatric-inpatient-care-100636607","NCT07567885","Brief Cognitive Behaviour Therapy to Prevent Suicide Reattempts: A Feasibility Study in Swedish Psychiatric Inpatient Care","BCBT","Inclusion Criteria:\n\n* admitted following a suicide attempt within one week of admission or presenting with suicidal ideation with a plan and a prior suicide attempt within the last two years\n* 18 years or older\n\nExclusion Criteria:\n\n* current mania, current acute psychosis, or cognitive impairment\n* expected inpatient stay shorter than four working days\n* ongoing or planned electroconvulsive therapy\n* psychiatric or somatic conditions leading to inability to provide informed consent",{"count":197,"type":20},32,[23],"The goal of this study is to determine whether Brief Cognitive Behaviour Therapy (BCBT), a four-session psychological treatment aimed at reducing suicide attempts, is acceptable and feasible to deliver during psychiatric inpatient care for adults who have been hospitalised following a suicide attempt or who are at high risk of suicide. The main questions it aims to answer are:\n\n1. Is BCBT acceptable among suicidal psychiatric inpatients, and in what ways can the treatment and its delivery be improved to enhance patient engagement and adherence?\n2. Is BCBT feasible from the perspectives of treating clinicians, clinic managers, and other relevant personnel, and what are the key facilitators and barriers to its implementation within routine inpatient psychiatric care in Sweden?\n\nParticipants will:\n\n* Receive four structured BCBT therapy sessions delivered during hospitalisation, in addition to usual care\n* Be contacted for follow-up assessments at 1 and 3 months after completing treatment\n* Take part in an interview about the participants' experience with the treatment 1 month after completing it\n\nClinical staff, treating psychologists, and managers will also be interviewed to explore the participants' experiences, as well as barriers and facilitators to implementation. Overall, the findings from this study will inform the design of a future randomised trial to test the effectiveness of BCBT in reducing suicide attempts after discharge from inpatient psychiatric care.",[27],"2026-04-28",{"date":183,"type":36},{"date":204,"type":20},"2026-04-27",{"date":206,"type":20},"2027-12-14",{"name":208,"class":43},"Karolinska Institutet",{"id":210,"slug":211,"hasResults":12,"nctId":212,"briefTitle":213,"officialTitle":213,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":214,"targetDuration":4,"studyType":21,"phases":216,"briefSummary":217,"conditions":218,"keywords":220,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":222,"lastUpdatePostDateStruct":223,"startDateStruct":225,"completionDateStruct":227,"leadSponsor":229,"locationsCount":44},"100590448","a-one-arm-open-trial-of-a-smartphone-delivered-treatment-for-suicidal-thoughts-and-behavior-100590448","NCT06967545","A One-Arm Open Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior",{"count":215,"type":20},20,[23],"This study aims to evaluate the acceptability, safety, and preliminary efficacy of a smartphone-delivered intervention called Therapeutic Evaluative Conditioning for Suicide (TEC-S) in reducing suicidal thoughts and behaviors (STB) among adults with recent and frequent suicide ideation.",[27,219],"Suicide Ideation",[29,221,31],"Ecological momentary assessment (EMA)","2026-04-15",{"date":224,"type":36},"2026-04-16",{"date":226,"type":36},"2026-01-20",{"date":228,"type":20},"2026-12-31",{"name":42,"class":43},{"id":231,"slug":4,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":232,"targetDuration":4,"studyType":21,"phases":233,"briefSummary":24,"conditions":234,"keywords":235,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":222,"lastUpdatePostDateStruct":236,"startDateStruct":238,"completionDateStruct":240,"leadSponsor":241,"locationsCount":44},"100568874",{"count":19,"type":20},[23],[26,27],[29,30,31],{"date":237,"type":36},"2026-04-20",{"date":239,"type":20},"2027-04-01",{"date":40,"type":20},{"name":42,"class":43},{"id":243,"slug":244,"hasResults":12,"nctId":245,"briefTitle":246,"officialTitle":247,"acronym":4,"eligibilityCriteria":248,"healthyVolunteers":12,"sex":16,"minAge":249,"maxAge":113,"enrollmentInfo":250,"targetDuration":4,"studyType":21,"phases":252,"briefSummary":253,"conditions":254,"keywords":258,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":261,"lastUpdatePostDateStruct":262,"startDateStruct":264,"completionDateStruct":266,"leadSponsor":268,"locationsCount":269},"100587688","suicide-preventive-psychosocial-treatment-for-youths-100587688","NCT06931639","Suicide Preventive Psychosocial Treatment for Youths","Suicide Preventive Psychosocial Treatment for Youths: A Randomized Controlled Trial","Inclusions criteria:\n\n1. Suicide attempt in the last 3 months\n2. Age 10-17 years\n3. At least one primary caregiver (multiple is allowed) willing to participate in treatment\n\nExclusion criteria:\n\n1. Symptoms obstructing participation in assessments or treatment\n2. Insufficient understanding of the Swedish language in youth and\u002For caregiver\n3. Enrolled in Dialectical Behavioral Therapy","10 Years",{"count":251,"type":20},282,[23],"Suicide is the leading cause of death amongst 10-18-year-olds in Sweden. Suicide attempts are the strongest predictor of subsequent death by suicide, often lead to inpatient care, and are associated with substantial societal costs, making suicide attempts a critical target in psychiatric intervention research. Although youths attempting suicide are typically assessed and treated for potential comorbid psychiatric conditions, there is currently no trans-diagnostic evidence-based treatment specifically targeting suicidal behavior. To fill this gap, the Safe Alternatives for Teens and Youths (SAFETY) was developed. SAFETY is a transdiagnostic family-based cognitive-behavioral suicide prevention program that has shown promise but more studies are needed.\n\nThe overall objective of this project is to evaluate the efficacy, durability, and cost-effectiveness of the SAFETY intervention, a scalable suicide prevention intervention that can be offered immediately following a youth suicide attempt, in a fully powered single-blind randomized controlled superiority trial. Our primary hypothesis is that the SAFETY intervention will be superior to Enhanced Treatment As Usual (enhanced with the evidence-based intervention safety planning) in reducing the proportion of suicide reattempts. Moreover, we predict that these improvements will be maintained for up to 60 months post-treatment. Finally, we expect that SAFETY will be cost-effective compared to the control intervention, both at the primary endpoint and in the longer term.",[27,255,256,257],"Suicidal and Self-injurious Behavior","Suicide Attempted","Suicide, Attempted",[259,260,27,176],"Safe Alternatives for Teens and Youths","Self-injurious Behavior","2026-04-14",{"date":263,"type":36},"2026-04-17",{"date":265,"type":36},"2025-05-28",{"date":267,"type":20},"2032-09",{"name":208,"class":43},5,{"id":271,"slug":272,"hasResults":12,"nctId":273,"briefTitle":274,"officialTitle":275,"acronym":276,"eligibilityCriteria":277,"healthyVolunteers":12,"sex":16,"minAge":146,"maxAge":4,"enrollmentInfo":278,"targetDuration":4,"studyType":21,"phases":280,"briefSummary":281,"conditions":282,"keywords":284,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":288,"lastUpdatePostDateStruct":289,"startDateStruct":291,"completionDateStruct":293,"leadSponsor":295,"locationsCount":44},"100543272","caring-connections-youth-suicide-detection-and-intervention-study-100543272","NCT06353711","Caring Connections Youth Suicide Detection and Intervention Study","CA-LINC Randomized Control Trial Study","CA-LINC","Inclusion Criteria:\n\nYouth:\n\n* 13 - 19 years old\n* Current or recent history (\\\u003C90 days) of suicide ideation, planning, or attempts or nonsuicidal self-injurious behaviors per youth or caregiver self-report or positive screen on the Patient Health Questionnaire Adolescent (PHQ-A), C-SSRS, or Ask Suicide-Screening Questions (ASQ).\n* Able to fluently speak and read English\n* Youth with a prior history of difficulty accessing services.\n* Written assent to participate in the study (\\\u003C18 years old)\n* Written consent from a parent\u002Flegal guardian\u002Fcaregiver to participate in the study (\\\u003C18 years old)\n* Written consent if the youth is ages 18-19\n\nParents\u002FLegal Guardians\u002FCaregivers:\n\n* The primary caregiver of a youth who meets the above inclusion criteria for the study\n* Over the age of 18\n* Able to fluently speak and read English\n* Without intellectual disabilities\n* Provide written consent to participate\n\nMental Healthcare and\u002For Healthcare Providers and\u002For Community Stakeholders:\n\n* Mental Health, behavioral health, substance use and\u002For health-related professionals who screen\u002Fassess for mental health and\u002For suicide risk or provide referrals, treatment, or follow-up care to youth with a prior history of difficulty accessing services in the surrounding treatment areas based on this risk or community stakeholder (i.e., faith-based leaders, agency directors, advocates, school administrators, hospital\u002Fcrisis directors, topical experts, etc.).\n* Over the age of 18\n* Able to fluently speak and read English\n* Without intellectual disabilities\n* Provide written consent to participate\n\nCare Coordinators:\n\n* Care coordinators who screen\u002Fassess for mental health and\u002For suicide risk or provide referrals, treatment, or follow-up care to underserved youth in the surrounding treatment areas.\n* Over the age of 18\n* Able to fluently speak and read English\n* Without intellectual disabilities\n\nExclusion Criteria:\n\nYouth:\n\n* Youth at imminent suicide risk (reported verbally and\u002For indicated on C-SSRS)\n* Youth who exhibit severe cognitive, language, or developmental delays\n* Youth not meeting inclusion criteria\n\nParents\u002FLegal Guardians\u002FCaregivers:\n\n* Not meeting the inclusion criteria listed above.\n\nMental Healthcare and\u002For Healthcare Providers and\u002For Community Stakeholders:\n\n* Not meeting the inclusion criteria listed above.",{"count":279,"type":20},180,[23],"The goal of this pilot randomized control trial (RCT) is to test the feasibility of Caring Connections, a Culturally Adapted Linking Individuals Needing Care (CA-LINC) suicide prevention care coordination intervention for high-risk suicidal youth. This consumer-, community-, and theory-driven care coordination intervention is designed to reduce suicide ideation and behavior (SIB) by improving service engagement. Connections is a 90-day intervention that integrates engagement and follow-up strategies to assess\u002Fmonitor suicide risk, facilitate service use referrals\u002Flinkages, develop\u002Frefine safety plans, and create villages of care. The intervention incorporates cultural promotive factors, empowerment, and motivational strategies aimed at supporting youth, enhancing strengths, promoting hope, improving family relationships, and reinforcing caring messages. Primary research questions include:\n\nIs Caring Connections feasible to use for suicidal high-risk youth? Does Caring Connections have the potential to reduce suicide ideation and behaviors among high-risk suicidal youth?\n\nFor the pilot RCT, 80 youth participants ages 13-19 who meet the inclusion criteria will be randomly assigned to one of two conditions: Caring Connections (n=40) or Treatment as Usual (n=40). Additionally, investigators will enroll 80 caregivers of youth meeting inclusion criteria and 20 Mental Healthcare, Healthcare Providers, Community Stakeholders, and\u002For Care Coordinators with experience working with suicidal youth. Researchers will compare those receiving Caring Connections with treatment as usual to see if suicidal ideation and behaviors, and engagement.",[29,283,219,27],"Suicide Prevention",[285,90,286,287],"Black youth","ideation","attempts","2026-03-13",{"date":290,"type":36},"2026-03-17",{"date":292,"type":36},"2025-08-14",{"date":294,"type":20},"2026-10",{"name":296,"class":43},"University of North Carolina, Chapel Hill",{"id":298,"slug":299,"hasResults":12,"nctId":300,"briefTitle":301,"officialTitle":301,"acronym":4,"eligibilityCriteria":302,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":303,"targetDuration":4,"studyType":21,"phases":305,"briefSummary":306,"conditions":307,"keywords":308,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":310,"lastUpdatePostDateStruct":311,"startDateStruct":312,"completionDateStruct":314,"leadSponsor":316,"locationsCount":318},"100629074","safety-planning-intervention-in-swedish-healthcare-a-multisite-study-for-suicide-prevention-100629074","NCT07469917","Safety Planning Intervention in Swedish Healthcare: A Multisite Study for Suicide Prevention","Inclusion Criteria:\n\nPatients presenting to psychiatric services with suicidal ideation, suicidal planning, or a suicide attempt\n\nPatients receiving care in participating adult psychiatric emergency or inpatient units\n\nExclusion Criteria:\n\nAge under 18 years",{"count":304,"type":20},8000,[23],"Suicide is one of the leading causes of premature death and a prioritized public health concern.\n\nSafety Planning Intervention (SPI) is a method with strong international research support for reducing suicidal behaviour by enhancing individuals' strategies for crisis management and improving access to support. SPI is a single-session intervention lasting approximately 45 minutes, which any healthcare provider can deliver after a brief training. Despite promising results, the implementation of SPI in Swedish healthcare remains limited. This project examines how SPI can be integrated into various healthcare settings and evaluates its impact on suicide-related emergency visits, psychiatric hospitalizations, and healthcare utilization. Data and Methods Stepped-Wedge implementation study in specialist psychiatry, where SPI is gradually introduced in psychiatric units. This study design allows for a robust evaluation of effects while ensuring all units eventually receive the intervention. As part of this study, a survey among healthcare professionals will be conducted to assess their experiences with feasibility, usability, and implementation barriers.\n\nData will be collected from QlikView healthcare utilization data. Poisson regression models with mixed effects will be used to analyze the impact of SPI on emergency visits and psychiatric hospitalizations. A health economic analysis will be conducted to evaluate the cost-effectiveness of SPI. Societal Relevance and Impact\n\nThe project contributes to Sweden's national suicide prevention strategy by:\n\n1. Scientifically evaluating the feasibility and effects of SPI in Swedish healthcare.\n2. Developing training programs for healthcare professionals in suicide prevention.\n3. Informing policy decisions and national guidelines.\n4. Analyzing the cost-effectiveness of SPI from a societal perspective. Implementation The research team includes experts in suicide prevention, psychiatry, epidemiology, patient safety, and health economics, creating a strong multidisciplinary foundation. The Stepped-Wedge design ensures an ethically and methodologically sound evaluation of SPI.\n\nGradual implementation allows for time-based comparisons, minimizes selection bias, and ensures all patients receive the intervention. The project is conducted in close collaboration with healthcare providers and policymakers to ensure that research findings can be integrated into clinical practice and strengthen suicide prevention efforts in Sweden.",[27],[309],"prevention of suicidality","2026-03-09",{"date":288,"type":36},{"date":313,"type":36},"2025-10-01",{"date":315,"type":20},"2029-07-01",{"name":317,"class":43},"Region Skane",4,{"id":320,"slug":321,"hasResults":12,"nctId":322,"briefTitle":323,"officialTitle":323,"acronym":324,"eligibilityCriteria":325,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":326,"targetDuration":4,"studyType":21,"phases":328,"briefSummary":329,"conditions":330,"keywords":332,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":336,"lastUpdatePostDateStruct":337,"startDateStruct":338,"completionDateStruct":340,"leadSponsor":342,"locationsCount":44},"100611254","augmenting-massed-cognitive-processing-therapy-cpt-to-prevent-suicide-risk-among-patients-with-ptsd-100611254","NCT07238192","Augmenting Massed Cognitive Processing Therapy (CPT) to Prevent Suicide Risk Among Patients With PTSD","mCPT+CRP","Inclusion Criteria:\n\n1. Active duty service member or veteran aged 18 or older eligible for military medical care.\n2. Able to read, write, and speak English.\n3. Meeting diagnostic criteria for PTSD or subthreshold PTSD (i.e., meeting diagnostic threshold for 3 of 4 symptom criteria within the past month) on the Clinician Administered PTSD Scale for DSM-5 (CAPS-5).\n4. Active suicidal ideation within the past week as assessed by scoring ≥ 1 on Scale for Suicidal Ideation (SSI) item 4 (i.e., active suicidal ideation within the past month) or report an interrupted, aborted, or actual suicide attempt within the preceding month on the Self-Injurious Thoughts and Behaviors Interview-Revised (SITBI-R).\n5. Regular use of an iPhone or Android smartphone.\n\nExclusion Criteria:\n\n1. Inability to comprehend and complete the consent and baseline screening questionnaires.\n2. Current suicide or homicide risk meriting crisis intervention.\n3. Serious mental health symptoms, such as mania, psychosis, alcohol or substance use disorders warranting immediate clinical attention based on interviewer assessment and clinical judgement.\n4. Currently engaged in evidence-based psychotherapy for PTSD (e.g., Cognitive Processing Therapy, Prolonged Exposure Therapy, Written Exposure Therapy).",{"count":327,"type":20},190,[23],"The purpose of this research is to see if Crisis Response Planning (CRP), a brief strategy designed to help people cope effectively with emotional crises, combined with Cognitive Processing Therapy (CPT), a talk treatment for posttraumatic stress disorder (PTSD), will reduce suicidal thoughts and behaviors.",[331,26,27],"Posttraumatic Stress Disorder (PTSD)",[333,334,93,90,335],"PTSD","Cognitive Processing Therapy","Crisis Response Planning","2026-02-23",{"date":100,"type":36},{"date":339,"type":36},"2026-01-28",{"date":341,"type":20},"2028-08-31",{"name":343,"class":43},"Ohio State University",{"id":345,"slug":346,"hasResults":12,"nctId":347,"briefTitle":348,"officialTitle":349,"acronym":350,"eligibilityCriteria":351,"healthyVolunteers":12,"sex":16,"minAge":112,"maxAge":4,"enrollmentInfo":352,"targetDuration":4,"studyType":354,"phases":4,"briefSummary":355,"conditions":356,"keywords":357,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":364,"lastUpdatePostDateStruct":365,"startDateStruct":367,"completionDateStruct":368,"leadSponsor":370,"locationsCount":44},"100625396","preventing-suicide-with-digital-phenotyping-and-pharmacogenetics-based-interventions-100625396","NCT07422090","Preventing Suicide With Digital Phenotyping and Pharmacogenetics-Based Interventions","Prevention of Suicidal Behavior Through Therapeutic Interventions Guided by Digital Phenotype and Pharmacogenetics: The SMARTomicS Study Protocol","SMARTomicS-R","Inclusion Criteria:\n\n1. At least one suicide attempt in their lifetime.\n2. The attempt must have occurred when the participant was older than 12 years old.\n3. Participants must be at least 18 years old or have parental consent if aged 12-17.\n\nExclusion Criteria:\n\n* medical contraindication prevents blood sample collection\n* unable to provide informed consent to participate in the study",{"count":353,"type":20},5000,"OBSERVATIONAL","The goal of this protocol for an observational retrospective multi-site cohort study is to develop a predictive algorithm for suicidal behavior integrating genetic risk markers, digital phenotypes, and exposomic data in people with a lifetime history of suicide attempt. Participants will be aged from 12 onwards (requiring parental consent if under 18) and only be excluded if they are unable to provide a genetic sample or do not consent to the study. The main question\\[s\\] it aims to answer is:\n\n\\- Can genotyping\u002Fomics analysis of individuals with a history of suicidal behaviuor reveal potential genetic factors associated with suicide risk?\n\nSecondary questions include:\n\n1. Can behavioral factors associated with suicide risk be explored through data obtained from Google Takeout?\n2. Is there an association between medication changes and suicidal behavior, as identified through the Unified Prescription Module and the Digital Health Record?\n3. Do different suicidal phenotypes differ based on the collected variables?\n4. Can the investigators construct an exposome using geolocated and time-stamped data from Google Takeout, combined anonymously with data from the National Statistics and Meteorology Institutes?\n\nThe investigators hypothesize that:\n\n1. Individuals with a history of suicidal behavior will show significant genotypic differences compared to the general population (based on Spanish Genome Project data).\n2. Suicidal phenotypes-especially between single and multiple attempters-will differ across collected variables, including genotype, omics, and exposome data.\n\nparticipants will complete genetic assessments, digital phenotypes, clinical questionnaires and exposomic data",[27],[90,91,358,359,360,361,362,363],"suicidal ideation","phenotyping","digital medicine","eHealth","genetic","exposome","2026-02-18",{"date":366,"type":36},"2026-02-19",{"date":72,"type":36},{"date":369,"type":20},"2028-01",{"name":371,"class":43},"Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz",{"id":373,"slug":374,"hasResults":12,"nctId":375,"briefTitle":376,"officialTitle":377,"acronym":378,"eligibilityCriteria":379,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":380,"targetDuration":4,"studyType":21,"phases":382,"briefSummary":383,"conditions":384,"keywords":386,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":364,"lastUpdatePostDateStruct":403,"startDateStruct":405,"completionDateStruct":407,"leadSponsor":409,"locationsCount":44},"100533288","efficacy-effectiveness-and-implementation-of-jaspr-health-in-emergency-department--part-a-100533288","NCT06223867","Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part A","Evaluation of Efficacy, Effectiveness, and Implementation of Jaspr Health's Digital Platform in Emergency Department for Patients With Suicidal Risk- Part A: Randomized Controlled Trial","Jaspr-PartA","Inclusion Criteria:\n\n* Positive for suicide risk on the Patient Safety Screener in the ED (active suicidal ideation int the past 2 weeks, or suicidal attempt in the past 6 months)\n* Cognitively and emotionally capable of consent and engaging in Jaspr app.\n* Reads English at 6th grade level.\n* Reliable telephone access.\n* Owns a smart phone\n* Lives in Massachusetts\n\nExclusion Criteria:\n\n* Prisoners or in state custody\n* Adults unable to consent\n* Patient \\\u003C18 yeas\n* Enrolled subjects during the 12 month follow-up period",{"count":381,"type":20},670,[23],"This Study will comprehensively evaluate a multi-component suicide prevention technology (Jaspr Health) that facilitates delivery of suicided-related evidence-based practices (EBPs) while replacing wasted waiting time with productive time in the Emergency Departments (EDs). The EBPs satisfy several key performance elements for systems adopting Zero Suicide.\n\nA Complementary Randomized Controlled Trial and Real-World Study for Efficacy, Effectiveness, and Implementation Study Design (CREID) will be used",[26,27,385],"Self Harm",[29,387,388,389,390,391,392,393,394,395,396,397,398,399,400,401,119,402],"Self-Harm","Attempt","Ideation","Suicidal thought","Suicidal plan","Crisis intervention","Suicide prevention","Emotional support","Mental Health","Behavioral Health","Psychiatry","Emergency Department","Technology","Mobile Application","Implementation","Lethal Means",{"date":404,"type":36},"2026-02-20",{"date":406,"type":36},"2024-02-23",{"date":408,"type":20},"2028-03-31",{"name":410,"class":43},"University of Massachusetts, Worcester",{"id":412,"slug":413,"hasResults":12,"nctId":414,"briefTitle":415,"officialTitle":416,"acronym":417,"eligibilityCriteria":418,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":419,"targetDuration":4,"studyType":21,"phases":421,"briefSummary":422,"conditions":423,"keywords":424,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":429,"lastUpdatePostDateStruct":430,"startDateStruct":432,"completionDateStruct":434,"leadSponsor":436,"locationsCount":44},"100545180","smartphone-app-enhanced-facilitation-among-veterans-in-a-mental-health-inpatient-setting-project-hope-100545180","NCT06378541","Smartphone App Enhanced Facilitation Among Veterans in a Mental Health Inpatient Setting (Project HOPE)","Virtual Hope Box Enhanced Facilitation in High-Risk Suicidal Veterans","Project HOPE","Inclusion Criteria:\n\nThose enrolled in the RCT component of this study must be:\n\n* 1\\) Veterans aged 18 or older\n* 2\\) admitted to the inpatient psychiatric unit for a recent suicidal crisis\n* 3\\) medically stable (the patient's medical and psychological fitness \\[including aggression\\] to provide informed consent will be determined by a member of the patient's treatment team)\n* 4\\) A score of 3 or greater on the Callahan 6-item cognitive screening.\n* 5\\) report current suicidal ideation (Scale for Suicidal Ideation \\[SSI\\]; sum of items 4 and 5 \\> 0, referencing the week prior to their hospitalization) as reported during the screening interview\n* 6\\) no reported use of the VHB within the past 12-months\n* 7\\) access to a smartphone to download the VHB app\n\nExclusion Criteria:\n\nVeterans will be found ineligible for the program if:\n\n* 1\\) do not understand English\n* 2\\) are prisoners\n* 3\\) are unable to provide informed consent\n* 4\\) have profound psychotic symptoms and\u002For cognitive deficits that would prevent patients from understanding the content of the intervention and\u002For assessments\n* 5\\) to not have access to a smartphone",{"count":420,"type":20},928,[23],"This study will test whether a novel intervention, Virtual Hope Box Enhanced Facilitation (VHB-EF), reduces suicide risk in Veterans after discharge from inpatient psychiatric hospitalization. Additionally, this study will also conduct interviews with Veterans and healthcare providers to explore barriers and facilitators to future adoption of the VHB-EF intervention in healthcare settings.",[283,27,219],[425,426,427,428],"smartphone application","suicide prevention","virtual hope box","veterans","2026-02-04",{"date":431,"type":36},"2026-02-09",{"date":433,"type":36},"2025-03-26",{"date":435,"type":20},"2029-05-31",{"name":437,"class":104},"VA Office of Research and Development",{"id":439,"slug":440,"hasResults":12,"nctId":441,"briefTitle":442,"officialTitle":443,"acronym":444,"eligibilityCriteria":445,"healthyVolunteers":12,"sex":16,"minAge":446,"maxAge":17,"enrollmentInfo":447,"targetDuration":4,"studyType":21,"phases":448,"briefSummary":449,"conditions":450,"keywords":451,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":339,"lastUpdatePostDateStruct":457,"startDateStruct":459,"completionDateStruct":461,"leadSponsor":463,"locationsCount":44},"100606062","teen-recovery-through-inspiration-support-and-empowerment-100606062","NCT07170657","Teen Recovery Through Inspiration, Support, and Empowerment","Teen Recovery Through Inspiration, Support, and Empowerment (RISE)","Teen RISE","Inclusion Criteria:\n\n* Chief complaint of suicidal ideation, suicide attempt, depression, and\u002For anxiety\n* recently discharged from inpatient care or from emergency department\n* men and women ages 15-18 years old\n\nExclusion Criteria:\n\n\\- primary diagnosis of: substance use disorder, schizophrenia spectrum, intellectual development disorder, autism spectrum disorder (level II or III)","15 Years",{"count":54,"type":20},[23],"The goal of this pilot study is to test the effectiveness of a novel intervention for teenagers (ages 15-18) with mental health conditions who have been released from an acute care psychiatric facility. The intervention aims to reduce suicidality, depression, anxiety, re-hospitalization, and to improve mental health recovery by using an online recovery education and support program.\n\nThe current standard of care (SOC) for these patients at discharge includes a discharge plan with a list of their medication(s), anticipated outpatient appointment(s), and corresponding information on when and where to find community resources.\n\nThe intervention being tested involves the implementation of an online recovery education and support (RES) program, involving one-on-one and small group meetings led by trained teen peers (TPs) and peer support specialists (PSS).\n\nParticipants will be assigned to either Cohort A or B for 8 weeks.\n\nCohort A will be the intervention group with online access to an RES, TP, and PSS.\n\n* Week 1-4: One-on-one meetings with PSS and TP for education and support. Assessments will be completed at week 2 and 4.\n* Week 5 and 7: one-one meetings with PSS and TP for education and support.\n* Week 6 and 8: small group meetings with PSS, TP, and other participants. Assessments will be completed during Weeks 6 and 8.\n\nCohort B will be the SOC group with no PSS, TP, or RES.\n\n* Weeks 1-4: Weekly check in phone calls with a member of the research team. Assessments will be completed at Weeks 2 and 4.\n* Weeks 5-8: Check in phone calls with a member of the research team every other week. Assessments will be completed at weeks 6 and8.\n\nData collected from participant assessments, adherence to medication, and re-admittance to a psychiatric facility will be used to compare the intervention to the SOC.",[26,27,58,59],[61,452,453,454,65,63,455,456],"Recovery Education and Support (RES) Program","Teenage","High School Teen","Online","Virtual",{"date":458,"type":36},"2026-01-30",{"date":460,"type":36},"2025-11-05",{"date":462,"type":20},"2026-11",{"name":76,"class":43},{"id":465,"slug":466,"hasResults":12,"nctId":467,"briefTitle":468,"officialTitle":469,"acronym":4,"eligibilityCriteria":470,"healthyVolunteers":12,"sex":16,"minAge":112,"maxAge":113,"enrollmentInfo":471,"targetDuration":4,"studyType":21,"phases":473,"briefSummary":474,"conditions":475,"keywords":476,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":481,"lastUpdatePostDateStruct":482,"startDateStruct":484,"completionDateStruct":485,"leadSponsor":487,"locationsCount":318},"100617965","plan-and-protect-safety-planning-for-teens-in-rural-emergency-departments-100617965","NCT07325474","Plan and Protect: Safety Planning for Teens in Rural Emergency Departments","Development & Implementation of Culturally Sensitive Safety Planning to Reduce Suicide Risk in Adolescents Seeking Care in Rural Emergency Departments","Inclusion criteria for children:\n\n* 12-17 years of age (and their parent\u002Fcaregiver(s))\n* Ability to speak and complete surveys in English\n* History of emergency department visit for suicidality, self-harm or mental health crisis\n* Medically stable\n\nExclusion criteria for children:\n\n* Cognitive or developmental delays that preclude program participation based on clinical team assessment\n* Diagnosis of psychosis\n* Primary diagnosis of an eating disorder\n* Parent\u002Fguardian not able to provide consent in English\n* Clinical team concern for patient or staff safety based upon active behavioral concerns\n* Parent\u002Fguardian not available to provide consent (e.g youth is in child protective custody\u002Fward of the state)\n\nInclusion criteria for parents\u002Fcaregivers:\n\n* Parent or caregiver of an eligible child\n* 18 years old or older\n* Ability to speak and complete surveys in English\n\nExclusion criteria for parents\u002Fcaregivers:\n\n-Inability to understand key aspects of the study",{"count":472,"type":20},550,[23],"The goal of this observational study is to determine whether implementing a culturally sensitive, tablet-based safety planning program called Plan \\& Protect (P\\&P) within rural emergency departments can improve home safety and reduce suicide risk in adolescents presenting with suicidality.\n\nThe main questions it aims to answer are:\n\n* Will implementing P\\&P increase caregiver-reported home safety (reduce access to firearms and unsafe medication storage) for adolescents 12-17 years old presenting to rural EDs with suicidal ideation, self-harm, or mental health crisis?\n* Will implementing P\\&P decrease adolescent-reported perceived suicide risk and related outcomes (e.g., suicide events, and attendance at follow-up mental healthcare)?\n\nResearchers will compare outcomes for adolescents and caregivers receiving P\\&P (implemented as the new standard of care at sites during the intervention periods) to those receiving usual care (prior to P\\&P implementation at those hospitals) to see if P\\&P increases home safety and decreases suicide risk and related healthcare utilization.\n\nParticipants will, if clinically appropriate:\n\n* Complete the tablet-based P\\&P modules during their ED visit\n* Complete self-report measures at baseline, \\~30 days, and \\~3 months post-discharge\n* A subset will also participate in semi-structured interviews",[219,27],[29,477,478,479,480],"Safety Planning","Adolescent","Mental Health Services","Emergency Services","2026-01-27",{"date":483,"type":36},"2026-01-29",{"date":155,"type":20},{"date":486,"type":20},"2028-09-30",{"name":488,"class":43},"Dartmouth-Hitchcock Medical Center",{"id":490,"slug":491,"hasResults":12,"nctId":492,"briefTitle":493,"officialTitle":494,"acronym":495,"eligibilityCriteria":496,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":497,"targetDuration":499,"studyType":354,"phases":4,"briefSummary":500,"conditions":501,"keywords":503,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":508,"lastUpdatePostDateStruct":509,"startDateStruct":511,"completionDateStruct":513,"leadSponsor":515,"locationsCount":44},"100614795","suicidal-ideation-framework-grounded-theory-study-catalonia-100614795","NCT07284238","Suicidal Ideation Framework: Grounded Theory Study, Catalonia","Process of Configuring the Suicidal Ideation Framework: A Grounded Theory Study in Catalonia, Spain","SUIF-GT-CAT","Inclusion Criteria:\n\n* Adults ≥18 years of age.\n* Usual residence in Catalonia (Spain).\n* Ability to understand, speak, read, and write in Catalan or Spanish.\n* Belonging to one of the three defined analytical groups:\n\n(A) Individuals who have attempted suicide within the past 6 months to 3 years. (B) Members of their family, social, or community support networks. (C) Healthcare professionals directly involved in the care of individuals who have attempted suicide.\n\n* Demonstrated clinical\u002Femotional stability ensuring safe participation, as confirmed by the referring clinician.\n* For individuals with lived experience (Group A): at least 6 months since the last suicide attempt or acute clinical crisis.\n* For support networks (Group B): having maintained meaningful proximity or involvement during or after the suicide attempt.\n* For healthcare professionals (Group C): minimum of 1 year of professional experience in mental health care.\n\nExclusion Criteria:\n\n* Presence of acute clinical decompensation preventing safe participation.\n* Active suicidal risk or acute crisis at the time of recruitment.\n* Acute vulnerability identified during screening.\n* Inability to provide informed consent.\n* Direct hierarchical dependence or conflict of interest with the research team (for Group C).",{"count":498,"type":20},45,"1 Day","This doctoral project aims to develop a comprehensive theoretical model of the process through which the suicidal ideation framework is configured as a symbolic, narrative, and relational expression, adopting a multiperspective approach that spans the suicide attempt and the stages of care and recovery. Moving away from biomedical reductionisms, this investigation seeks to identify shared meaning-making nuclei and discursive fractures that reflect the inherent conflictuality of the suicidal act.\n\nGrounded in the integration of the theoretical frameworks previously outlined, this study adopts an interpretive-constructivist approach. Phase 1 will include studies conducted in OECD countries, providing a broad and conceptually diverse interpretive foundation. Phase 2, conducted in Catalonia, will deepen situated configurations, assuming that local sociocultural frameworks act as interpretive prisms for globally relevant phenomena.\n\nOverall, this theoretical-methodological architecture not only ensures conceptual robustness and coherence, but also articulates an ethical and epistemic commitment to understanding suicide through the complexity of its human textures. By centering suffering, listening to historically silenced voices, honoring the singularity of each life trajectory, and grounding the inquiry in an ethics of care, this study aims to transcend a merely technical-instrumental logic of knowledge.",[29,27,219,502,283],"Suicide Risk",[26,29,504,505,506,507],"Meta-synthesis","Grounded Theory","Mental Health Nursing","High-Income Countries","2025-12-02",{"date":510,"type":36},"2025-12-16",{"date":512,"type":20},"2026-03",{"date":514,"type":20},"2027-09",{"name":516,"class":43},"Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau",{"id":518,"slug":519,"hasResults":12,"nctId":520,"briefTitle":521,"officialTitle":522,"acronym":4,"eligibilityCriteria":523,"healthyVolunteers":12,"sex":16,"minAge":524,"maxAge":4,"enrollmentInfo":525,"targetDuration":4,"studyType":21,"phases":527,"briefSummary":528,"conditions":529,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":530,"lastUpdatePostDateStruct":531,"startDateStruct":533,"completionDateStruct":534,"leadSponsor":536,"locationsCount":539},"100580026","attempted-suicide-short-intervention-program-for-older-adults-assip-oa-an-evaluation-of-a-psychosocial-intervention-for-suicidal-adults-aged-65-100580026","NCT06831942","Attempted Suicide Short Intervention Program for Older Adults (ASSIP-OA): An Evaluation of a Psychosocial Intervention for Suicidal Adults Aged 65+","Attempted Suicide Short Intervention Program for Older Adults (ASSIP-OA): An RCT and a Qualitative Evaluation of a Psychosocial Intervention for Suicidal Adults Aged 65+","Inclusion Criteria:\n\n1. Age 65 and above at time of index suicide attempt or hospitalisation for serious suicidal plans.\n2. A mental health care contact during the active treatment period.\n3. Capable of understanding study procedures and providing informed consent.\n\nExclusion Criteria:\n\n1. Clinical diagnosis of dementia or MoCa score less than -2 standard deviations from the normative score for education and age (Borland et al., 2017). Ongoing delirium, or any other condition impeding the comprehension of the study's procedures and implications that hinder the provision of informed consent.\n2. Severe ongoing psychosis, severe ongoing substance use disorder, emotionally instable personality syndrome and any other condition that would require longer specialized treatment to reduce future suicidal behaviour (e.g. DBT).\n3. Terminal illness.\n4. Insufficient knowledge of the Swedish language (requires interpreter).\n5. Aphasia or other severe communication issue or severe hearing and\u002For severe visual impairment that render the intervention unfeasible despite corrective aids.","65 Years",{"count":526,"type":20},132,[23],"Older adults are sorely underrepresented in suicide prevention research, despite the fact that suicide rates are higher in this age group than in any other age group in Sweden and in many countries worldwide. There are extremely few clinical intervention studies that target this age group, with to date no published studies in Europe. The overall aim is to develop and test a modified version of the Attempted Suicide Short Intervention Program (ASSIP), which the investigators will adapt specifically for older adults (65+). The original ASSIP was developed in Switzerland where it has shown an 80% decrease in risk of new suicide attempts compared to ordinary treatment. In Sweden, ASSIP is currently being tested for persons aged 18+ . The investigators now propose a randomised controlled trial (RCT) to evaluate a modification of ASSIP specifically designed to meet the needs of suicidal persons aged 65 and above, the ASSIP-Older Adult program (ASSIP-OA).\n\nMain study questions\n\n1. Compared to treatment as usual (TAU), will the addition of the ASSIP-OA to ordinary treatment have a preventive effect on suicide and suicide attempts within 6, 12, and 24 months following the index episode?\n2. Compared to TAU, do ASSIP-OA participants show better improvement in coping skills and psychiatric symptoms a) after the last session and b) at 6-,12- and 24- month follow-up?\n3. Is a brief preventive intervention (ASSIP-OA) for older adults feasible, based on its acceptability, appropriateness, deliverability and fidelity? Do participants experience side effects? Do they have fewer days of inpatient care?\n4. What kind of challenges and opportunities do a) older adults and b) ASSIP-OA therapists experience in relation to implementing a brief preventive intervention like ASSIP-OA? Are the modifications that the investigators made in ASSIP-OA relevant for older adults?",[26,27,29],"2025-11-17",{"date":532,"type":36},"2025-11-18",{"date":313,"type":36},{"date":535,"type":20},"2031-06",{"name":537,"class":538},"Vastra Gotaland Region","OTHER_GOV",2,{"id":541,"slug":542,"hasResults":12,"nctId":543,"briefTitle":544,"officialTitle":545,"acronym":4,"eligibilityCriteria":546,"healthyVolunteers":12,"sex":16,"minAge":112,"maxAge":113,"enrollmentInfo":547,"targetDuration":4,"studyType":21,"phases":549,"briefSummary":550,"conditions":551,"keywords":554,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":559,"lastUpdatePostDateStruct":560,"startDateStruct":562,"completionDateStruct":564,"leadSponsor":566,"locationsCount":318},"100604539","efficacy-of-the-i-care-digital-health-intervention-100604539","NCT07150832","Efficacy of the I-CARE Digital Health Intervention","I-CARE: Efficacy of a Digital Health Intervention to Reduce Suicidal Ideation During Psychiatric Boarding","Inclusion Criteria:\n\n* Adolescents of any sex and gender, aged 12-17 years at ED visit or hospital encounter\n* Presenting with suicide attempt or ideation, or self-harm\n* Medically stable\n* English-speaking\n* Awaiting transfer for inpatient psychiatric care or disposition.\n\nExclusion Criteria:\n\n* Cognitive or developmental delays precluding participation (intellectual functioning \\\u003C12 years of age)\n* Behavioral limitations that preclude program participation\n* Active psychosis\n* Legal parent\u002Fcaregiver unable to speak English or unavailable to provide consent (e.g. Wards of the State)",{"count":548,"type":20},173,[23],"When presenting to an ED with suicide, self-harm or other mental health crises, youth may also experience \"boarding\", which is defined by the Joint Commission as \"the practice of holding patients in the ED or another temporary location after the decision to admit or transfer has been made.\" A recent national survey of 88 US acute care hospitals conducted by our research team found that 98.9% of hospitals were boarding youth awaiting psychiatric hospitalization, for an average of 2-3 days. However, as illustrated in a systemic review, little research has focused on developing interventions to support youth during this highly vulnerable time. 3\n\nI-CARE is a modular, blended digital health intervention facilitated by individuals who are not mental health clinical staff to teach youth evidence-based psychosocial skills during the boarding period. This study will evaluate I-CARE's efficacy using a patient-level randomized clinical trial (RCT), randomizing youth to receive standard safety supervision or I-CARE in addition to standard safety supervision. If found to the efficacious, I-CARE could be scaled-up in new settings with limited resources and has the potential to significantly improve the quality of care received by youth experiencing boarding.",[552,27,26,553],"Mental Health Disorder","Emergency Psychiatric",[555,556,398,557,558],"Children","Adolescents","Mental Health Boarding","Psychosocial Skills","2025-10-29",{"date":561,"type":36},"2025-10-31",{"date":563,"type":36},"2025-10-06",{"date":565,"type":20},"2027-06-30",{"name":488,"class":43},{"id":568,"slug":569,"hasResults":12,"nctId":570,"briefTitle":571,"officialTitle":572,"acronym":573,"eligibilityCriteria":574,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":575,"targetDuration":4,"studyType":21,"phases":577,"briefSummary":578,"conditions":579,"keywords":580,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":581,"lastUpdatePostDateStruct":582,"startDateStruct":584,"completionDateStruct":586,"leadSponsor":588,"locationsCount":44},"100605280","efficacy-of-a-smartphone-suicide-prevention-app-100605280","NCT07160465","Efficacy of a Smartphone Suicide Prevention App","Efficacy of a Smartphone Suicide Prevention App: A Single-blind, Randomized, Controlled Multicenter Study","PreventS","Inclusion Criteria:\n\n* Subject aged 18 or over\n* Subject benefiting from the VigilanS program (after an admission to an emergency ward following a suicide attempt)\n* Subject with his own smartphone (iOS\u002FAndroïd)\n* Subject able to understand the nature, purpose and methodology of the study\n* Subject must be covered by public health insurance\n* Signed informed consent form\n\nExclusion Criteria:\n\n* Subject unable to read or\u002Fand write French\n* Planned longer stay outside the region that prevents compliance with the visit plan\n* Being protected by the law (tutorship or curatorship)\n* Being deprived of liberty by administrative decision\n* Being in a period of exclusion compared to another protocol\n* Pregnant and breastfeeding women",{"count":576,"type":20},632,[23],"It is an interventional research, single-blind, randomized, controlled, multicenter, which involves only minimal risks and constraints.\n\nPatients who attend to the emergency department following a SA (Suicidal Attempt) represent a key group of patients with an extremely high risk of suicide in the short term.\n\nA main problem in suicide prevention is that the increase of symptoms and suicidal risk occurs most often in the natural environment of patients, away from the system of care. Thus, the main goal in allowing real-time risk detection would facilitate immediate interventions, probably the best way to prevent a suicidal act. Additionally, the evolution of the suicidal crisis is very variable from one subject to another, in duration and symptoms, and often very brief. In contrast, the tools used to assess suicidal thoughts have so far been limited to intermittent assessments separated by weeks, months or years, which does not take into account the fact that suicidal thoughts can be highly variable over a few hours and that suicide attempts can occur in response to a rapid increase in thoughts over periods as short as the day. Mobile health (mHealth) interventions are the only that can respond to these fluctuations over time.\n\nWe have developed the first French app (emma) for EMA (Ecological Momentary Assessment) , customised EMI (Ecological Momentary Intervention) and prediction of SB (suicidal behaviour). It was designed by integrating evidence-based suicide prevention strategies and recommendations for the development of apps in the field of mental health. Emma helps to strengthen the patient's connection to his healthcare system and social network. This study led to the development and subsequent deployment of VigilanS. VigilanS is a multi-regional innovative care program for the prevention of suicide relapse, which has been implemented in several emergencies departments in France.\n\nOur hypothesis is that emma offers an unprecedented opportunity to increase the efficiency of VigilanS, both for patients, by restoring their social connections, and for health professionals, in a simple, fast and efficient way. Thanks to emma, the patient will have daily support adapted to his condition (emotion management modules, safety plan, calls in case of emergency). Emma will fit easily into the daily practice of health professionals (little binding, little time consuming) and will complete the range of care organized by VigilanS.\n\nThe main objective is to evaluate over a 6-months follow-up the efficacy of a smartphone app (emma) in addition to the VigilanS program on the prevention of a suicidal event (suicide, SA, hospitalization or emergency department for suicidal ideation) compared to the VigilanS program only.",[29,27],[29,125],"2025-08-29",{"date":583,"type":36},"2025-09-08",{"date":585,"type":20},"2025-09",{"date":587,"type":20},"2028-03",{"name":589,"class":43},"University Hospital, Montpellier",{"id":591,"slug":592,"hasResults":12,"nctId":593,"briefTitle":594,"officialTitle":595,"acronym":596,"eligibilityCriteria":597,"healthyVolunteers":169,"sex":16,"minAge":598,"maxAge":446,"enrollmentInfo":599,"targetDuration":4,"studyType":21,"phases":601,"briefSummary":602,"conditions":603,"keywords":604,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":611,"lastUpdatePostDateStruct":612,"startDateStruct":614,"completionDateStruct":616,"leadSponsor":618,"locationsCount":44},"100602563","piloting-a-culturally-adapted-suicide-prevention-for-black-students-in-chicago-100602563","NCT07125144","Piloting a Culturally Adapted Suicide Prevention for Black Students in Chicago","Piloting a Culturally Adapted Multilevel Suicide Prevention Intervention in Schools for Black Youth and Their Families","SP-BSC","Inclusion Criteria:\n\n* Enrolled in 6th, 7th, or 8th grade at a participating school\n\nExclusion Criteria:\n\n* Not enrolled in 6th, 7th, or 8th grade at a participating school","11 Years",{"count":600,"type":20},300,[23],"Suicide has been the third leading cause of death for Black youth in the U.S since the 1980s and persists as a leading cause of death for Black youth today. For example, in 2018 suicide was reported as the 2nd leading cause of death among Black Americans ages 10 to14 years old. Findings yielded from recent queries indicate that the gap in suicides among Black males and female youth has narrowed in recent years. Despite these disturbing trends, a dearth persists in our understanding of the factors that contribute to and prevent against suicide in Black youth, thus diminishing researchers' ability to effectively detect suicide risk in this particular population. This project aims to redress this gap by proposing the cultural adaptation of an existing suicide prevention intervention, the Signs of Suicide (SOS) prevention program, for Black middle school students. Our team will conduct a pilot randomized controlled trial among a sample of Black middle school students to assess feasibility and\n\nexamine underlying mechanisms that contribute to suicidality among Black youth. Intervention content will be adapted to assess how topics of racial identity, racial socialization, and racial discrimination uniquely impact Black youth's mental health experiences and risk for suicide. Measures of suicidal ideation, planning, and attempt will be assessed at pre-test, post-test, and 3-months after the intervention. Findings derived from this project will contribute to public health priorities by offering unique insight into the factors that either prevent or promote suicide among Black youth and could be replicated in other schools serving Black students across the nation.",[29,26,27],[605,606,90,426,94,607,608,609,610,478],"Black","youth","Signs of Suicide","Cultural Adaptation","Chicago","African American","2025-08-08",{"date":613,"type":36},"2025-08-15",{"date":615,"type":36},"2025-01-30",{"date":617,"type":20},"2026-07-31",{"name":619,"class":43},"University of Chicago",{"id":621,"slug":622,"hasResults":12,"nctId":623,"briefTitle":624,"officialTitle":624,"acronym":625,"eligibilityCriteria":626,"healthyVolunteers":12,"sex":16,"minAge":112,"maxAge":4,"enrollmentInfo":627,"targetDuration":499,"studyType":354,"phases":4,"briefSummary":629,"conditions":630,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":633,"lastUpdatePostDateStruct":634,"startDateStruct":636,"completionDateStruct":638,"leadSponsor":640,"locationsCount":642},"100594588","the-epidemiology-of-suicide-attempts-and-suicidal-thoughts-in-flanders-100594588","NCT07021404","The Epidemiology of Suicide Attempts and Suicidal Thoughts in Flanders","BC-03869","Inclusion Criteria:\n\n* Everyone who is admitted alive to the emergency department after a suicide attempt is included. All methods used during the suicide attempt are included. Regarding the method of suicide attempts, a distinction is made between self-injury (hanging, strangulation, drowning, stab and cut wounds, jumping from a height, etc.) and self-poisoning (ingestion of (psycho)pharmaceuticals, drugs, alcohol, chemicals, or other harmful substances).\n* Everyone who is admitted with suicidal thoughts\n\nExclusion Criteria:\n\n* Accidental overdose, e.g., someone taking medication for a medical condition without any intent to harm themselves\n* Alcohol intoxication without any intent to harm oneself\n* Accidental overdose involving party drugs\n* Individuals who were deceased upon arrival at the hospital due to suicide",{"count":628,"type":20},50000,"The objective of this study is to collect data in Flanders on the incidence of suicide attempts and suicidal ideation across various healthcare settings. The study also aims to assess the proportion of individuals who receive adequate aftercare following a suicide attempt and to systematically document the methods and means used in suicidal behavior.",[26,27,631,632,176],"Multicenter Study","Epidemiological Study","2025-06-05",{"date":635,"type":36},"2025-06-15",{"date":637,"type":36},"2006-12-31",{"date":639,"type":20},"2033-03-31",{"name":641,"class":43},"University Hospital, Ghent",33,{"id":644,"slug":645,"hasResults":12,"nctId":646,"briefTitle":647,"officialTitle":648,"acronym":4,"eligibilityCriteria":649,"healthyVolunteers":169,"sex":16,"minAge":112,"maxAge":650,"enrollmentInfo":651,"targetDuration":4,"studyType":21,"phases":653,"briefSummary":654,"conditions":655,"keywords":658,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":671,"lastUpdatePostDateStruct":672,"startDateStruct":674,"completionDateStruct":676,"leadSponsor":678,"locationsCount":4},"100592640","effects-of-a-multifaceted-school-based-intervention-to-protect-mental-health-and-prevent-suicidal-behaviour-in-adolescents-in-spain-100592640","NCT06996054","Effects of a Multifaceted School-Based Intervention to Protect Mental Health and Prevent Suicidal Behaviour in Adolescents in Spain","DEVELOPMENT AND EVALUATION OF A MULTIFACETED SCHOOL-BASED INTERVENTION TO PROTECT MENTAL HEALTH AND PREVENT SUICIDAL BEHAVIOR AMONG ADOLESCENTS IN SPAIN","Inclusion Criteria:\n\n* Students enrolled in the 2nd or 3rd year of compulsory secondary education during the 2026-2027 academic year in the Balearic Islands, Spain.\n* Aged between 12 and 16 years at the time of recruitment.\n* Provision of written informed consent from both the student and at least one parent\u002Flegal guardian.\n* Attending school centres with a student population composed of no more than 75% of a single gender.\n* Enrollment in a participating classroom randomly selected for the study.\n\nExclusion Criteria:\n\n* Presence of cognitive, developmental, or language impairments that, in the judgment of school staff or study personnel, would prevent the student from understanding the intervention content or completing the study assessments reliably.\n* Students currently receiving intensive psychological or psychiatric treatment for acute suicidality or severe mental health conditions that require individualized clinical management beyond the scope of a school-based programme.\n* Students or parents who explicitly decline participation in specific intervention components, such as group discussions on suicide or mental health.\n* Participation in a concurrent school-based mental health programme that could confound the effects of the intervention.","16 Years",{"count":652,"type":20},2280,[23],"What is this study about? This study aims to find out if a school-based program can help improve mental health and prevent suicidal thoughts and behaviors in teenagers in Spain. Suicide is one of the leading causes of death among young people. Many teens who think about or attempt suicide are also struggling with mental health problems like depression. Schools offer a unique opportunity to help because almost all adolescents attend school regularly.\n\nWhat will happen in the study?\n\nThe study will include about 2,280 students aged 12 to 16 years from 38 secondary schools in the Balearic Islands, Spain. Schools will be randomly assigned to one of two groups:\n\nIntervention group: Students will participate in four weekly classroom sessions led by trained psychologists. These sessions will help students learn about mental health, manage their emotions, recognize signs of distress in themselves or others, and ask for help when needed. At the same time, parents and teachers will follow a digital training program with videos and resources to help them support students' mental health and recognize warning signs.\n\nControl group: Students will receive a minimal intervention, which includes educational posters displayed in classrooms.\n\nWhat is the purpose of this program? The main goal is to reduce suicidal thoughts and behaviors. The program also aims to improve students' overall mental well-being, reduce depression symptoms, and encourage help-seeking behaviors. It also helps parents and teachers feel more confident in supporting teens who may be at risk.\n\nHow will the study be evaluated? Students will complete questionnaires at the start of the study and again after six months. These surveys will ask about mental health, suicidal thoughts, emotional well-being, self-harm, substance use, and experiences with bullying. Parents and teachers will also complete surveys about their knowledge and confidence in supporting students.\n\nWhy is this study important? There is an urgent need to find effective ways to prevent suicide and support young people's mental health. This program involves students, families, and schools in working together to create a safe and supportive environment. If the program works, it could be used in schools throughout Spain and possibly in other countries too.\n\nWho is funding this study? The study is funded by Fundación Mutua Madrileña.",[27,127,656,387,657],"Adolescent Mental Health","Suicidal Ideation and Behavior",[659,393,179,126,127,556,660,661,662,663,664,665,666,667,668,669,670],"School-based intervention","Mental health promotion","Psychoeducation","Gatekeeper training","Teachers","Parents","Digital health","Cluster randomized controlled trial","Spain","Secondary education","Emotional regulation","Self-harm","2025-05-21",{"date":673,"type":36},"2025-05-30",{"date":675,"type":20},"2025-10",{"date":677,"type":20},"2027-06",{"name":679,"class":538},"Fundació d'investigació Sanitària de les Illes Balears"]