[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"suicide-ideation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:suicide-ideation":412},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,14,0,[8,51,80,105,134,158,186,214,242,270,297,327,355,386],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":32,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100614420","deaf-cbt-ts-to-reduce-suicide-risk-100614420",false,"NCT07279363","Deaf CBT-TS to Reduce Suicide Risk","Cognitive Behavioral Therapy for Treatment-Seeking to Improve Treatment Engagement and Reduce Suicide Risk Among Deaf Individuals","Inclusion criteria:\n\n* adult (aged 18 years or older)\n* Self-identify as Deaf or hard of hearing (any degree of hearing loss)\n* Primary method of communication is American Sign Language\n* Positive screen for one or more mental health disorders including depression (PHQ-9 \\> 10), anxiety (GAD-7 \\> 10), posttraumatic stress disorder (PCL-5 \\> 31), insomnia (ISI \\> 15), or alcohol use disorder (AUDIT \\> 16)\n* No current professional mental health or alcohol specialty treatment (e.g., counseling, psychiatric services) per standardized self-report\n* Access to video chat technology with internet and webcam.\n\nExclusion criteria:\n\n* unable to communicate with the researcher in American Sign Language\n* current alcohol withdrawal necessitating medical evaluation\n* current psychiatric impairment necessitating emergency services or inpatient admission (i.e., imminent danger of harm to self or others)\n* unable to comprehend the nature of the study","ALL","18 Years",{"count":19,"type":20},110,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical trial is to learn if a short, Zoom-based intervention, Cognitive Behavioral Therapy for Treatment-Seeking for Deaf Individuals (Deaf CBT-TS) can change beliefs about mental health treatment and increase treatment-seeking behaviors in Deaf adults with untreated mental health or alcohol use problems. It will also see if Deaf CBT-TS may reduce suicide risk and explore factors that may increase the effectiveness of Deaf CBT-TS. The main questions it aims to answer are:\n\n* Does Deaf CBT-TS increase positive beliefs about treatment and increase treatment-seeking behaviors?\n* Does Deaf CBT-TS increase hope and reduce mental health symptoms, suicide ideation, and alcohol use?\n* Is Deaf CBT-TS more effective for individuals with less cultural stress compared to those with high levels of cultural stress?\n* Is Deaf CBT-TS more effective for Deaf individuals in residential areas with more Deaf resources than those with less Deaf resources? Researchers will compare individuals who complete Deaf CBT-TS to those on a waitlist to see if Deaf CBT-TS works to increase positive beliefs about treatment and treatment-seeking behaviors.\n\nParticipants will:\n\n* Complete a baseline assessment including demographic information, measures of hope, general mental health and functioning, alcohol use, suicide ideation, cultural stress, and beliefs about treatment.\n* Receive Deaf CBT-TS (2 sessions) or be placed on a waitlist with the option of receiving Deaf CBT-Ts after 4 months\n* Complete two follow-up assessments in 2 and 4 months.",[26,27,28,29,30,31],"Depression - Major Depressive Disorder","Anxiety","PTSD - Post Traumatic Stress Disorder","Insomnia","Alcohol Use Disorder (AUD)","Suicide Ideation",[33,34,35,36,37],"Deaf","Mental Health","Treatment-Seeking","Suicide","Cognitive Behavioral Therapy for Treatment-Seeking","NOT_YET_RECRUITING","2026-06-17",{"date":41,"type":42},"2026-06-22","ACTUAL",{"date":44,"type":20},"2026-09",{"date":46,"type":20},"2029-05",{"name":48,"class":49},"University of Rochester","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":21,"phases":60,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":4},"100639344","phase-3-brief-cognitive-behavioral-therapy-for-suicide-prevention-in-a-brazilian-sample-a-study-protocol-of-a-randomized-clinical-trial-100639344","NCT07574658","Brief Cognitive Behavioral Therapy for Suicide Prevention in a Brazilian Sample: a Study Protocol of a Randomized Clinical Trial","Study participants meet inclusion criteria if they are (1) Between the ages of 18-65; (2) Treatment-seeking status in outpatient mental health and\u002F or inpatient psychiatry discharge; (3) Report current (within the past week) suicide ideation (e.g., score greater than 2 on the Scale for Suicide Ideation) and\u002For a suicide attempt within the past month (e.g., as assessed by the Beck Scale for Suicide Ideation (BSI); (4) Able to understand and speak Portuguese; (5) Able to complete the informed consent process.","60 Years",{"count":59,"type":20},150,[61],"PHASE3","The vast majority of suicides occur in low-and middle-income countries (LMICs), and evidence on effective psychotherapeutic interventions to prevent suicide that are culturally adapted to these contexts is limited. This scenario implies an urgent need for evidence-based suicide prevention strategies in Brazil. This research aims to evaluate the effectiveness of brief cognitive-behavioral therapy in preventing suicide in an outpatient setting of a Brazilian university. A randomized, controlled clinical trial with two arms, whose participants are adults who have attempted suicide or have had suicidal ideation with intent to die, will be designed. Inclusion criteria will be suicidal ideation with intent to die in the last week and\u002For suicide attempt in the last month. Patients will be randomly assigned to receive either a weekly 12-session supportive therapy or brief cognitive-behavioral therapy. The duration of treatment will be approximately 3 months. Both groups will have weekly individual therapy. Follow-up contact will be made 1 month and 6 months after treatment. If necessary, patients are entitled to two booster sessions during the follow-up period. The outcomes to be assessed, a priori, are suicide attempts, self-harm without suicidal intent and suicidal ideation, assessed by the Beck Scale for Suicide Ideation (BSI). Linear mixed models will be used to assess the outcomes of continuous variables, logistic regression models for categorical outcomes and survival analysis for the analysis of suicide attempts.",[31,64],"Suicide Attempts",[36,66,67,68,69,70],"Suicide prevention","Brief Cognitive Behavioral Therapy (BCBT)","Randomized clinical trial","Evidence-based psychotherapy","Low- and middle-income countries (LMICs)","2026-05-04",{"date":73,"type":42},"2026-05-08",{"date":75,"type":20},"2026-05-10",{"date":77,"type":20},"2028-07-10",{"name":79,"class":49},"University of Sao Paulo",{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":86,"targetDuration":4,"studyType":21,"phases":88,"briefSummary":89,"conditions":90,"keywords":93,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":50},"100540601","examining-the-efficacy-of-a-digital-therapeutic-to-prevent-suicidal-behaviors-100540601","NCT06318962","Examining the Efficacy of a Digital Therapeutic to Prevent Suicidal Behaviors","Inclusion Criteria:\n\n* at least 18 years old\n* suicidal ideation within the past week and\u002For a suicide attempt within the past 30 days\n* ability to complete the informed consent process\n* ownership of either an Apple iPhone iOS 11 or higher or an Android smartphone OS 8.1 or higher\n\nExclusion Criteria:\n\n* an inability to complete informed consent procedures (e.g., acute intoxication, altered consciousness)\n* experiencing active psychosis or mania requiring hospitalization; (3) and inability to use a smartphone.",{"count":87,"type":20},400,[23],"The primary aim of the project is to test the efficacy of BCBT delivered via a digital platform (i.e., smartphone) to Servicemembers with recent suicidal ideation and\u002For suicide attempts presenting to primary care clinics. Given existing challenges of scaling empirically-supported treatments\u002Finterventions for suicidality with fidelity, this project could lead to markedly expanded access to BCBT, along with improving our understanding about what intervention strategies are most effective and how they can be delivered with meaningful fidelity. Aviva, the digital version of BCBT, was developed for use with patients across the full spectrum of healthcare settings, including primary care. Aviva is not an emergency alert system, rather a digital platform for delivery of the full scope of BCBT treatment components. An open-label single group Phase I clinical trial has demonstrated the safety, tolerability, feasibility, fidelity, and potential efficacy of Aviva, with participants completing modules over 8 weeks, and follow-up assessments at weeks 1, 4, and 8. Subsequent refinements included the addition of technical features that would allow patients to revisit and\u002For repeat previously completed modules, along with integration of more characters for delivering video vignettes and greater opportunities for skills practice and treatment engagement. These modifications have further enhanced Aviva safety, tolerability, and fidelity, consistent with the original BCBT protocol. Not only is it hypothesized that Aviva will result in significantly larger reductions in severity of suicidal ideation than participants randomized to the control condition, but also that greater app engagement will be negatively correlated with severity of suicidal thinking. Moderators and mediators (i.e. suicidal beliefs, wish to live, impulsive decision-making) of intervention effects will also be examined. The study will be conducted at the primary care clinics at Fort Carson, with a goal of enrolling 720 patients across a two-year timeframe. Participants will be identified using each clinic's existing suicide risk assessment methods, including the PHQ-9 suicide risk item and a score of 1 or higher on the CSSRS Screener (Recent). Participants will be randomly assigned to one of two treatment conditions, Aviva or control (i.e., development of a safety plan consistent with local procedures and policies, along with referral for standard mental health care and suicide risk management in accordance with local policies and procedures). In an effort to address potential performance bias specific to smartphone use, participants in the control condition will download the Suicide Safety Plan app to their smartphones. Those in the Aviva condition will also complete weekly check-ins with Project 2 research clinicians to review treatment adherence, identify and respond to any logistical\u002Foperational problems, and respond to any unexpected emergencies and\u002For participant safety concerns. Participants will have up to five data points: baseline, 3, 6, 9, and 12 months. All data available from all participants and all time points will be included in the analyses, consistent with the intent-to-treat principle. Across our two previous clinical trials and our in-progress RCT, attrition during the first 12 months postbaseline was \\<30% and we anticipate similar rates in this trial.",[91,31,92],"Suicidal Behaviors","Depression\u002FAnxiety",[94,31,64,95],"BCBT","Depression and Anxiety","RECRUITING",{"date":98,"type":42},"2026-05-05",{"date":100,"type":42},"2024-02-07",{"date":102,"type":20},"2027-08-01",{"name":104,"class":49},"University of Memphis",{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":109,"acronym":4,"eligibilityCriteria":110,"healthyVolunteers":11,"sex":16,"minAge":111,"maxAge":112,"enrollmentInfo":113,"targetDuration":4,"studyType":21,"phases":115,"briefSummary":116,"conditions":117,"keywords":120,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":133},"100527699","preventing-suicidal-behavior-with-diverse-high-risk-youth-in-acute-care-settings-100527699","NCT06151158","Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings","Inclusion Criteria:\n\n* Suicide Risk During Acute Care Visit (At least one item in risk assessment is required; check all that apply): \\_\\_\\_ Chief complaint of suicide-related concern (via Medical Record\u002FOther), \\_\\_\\_ Active suicidal ideation endorsed in past 1 month on validated suicide screener, \\_\\_\\_ Suicidal behavior in the past 3 months on validated suicide screener, \\_\\_\\_ Clinician indicated SI in past month or SA in past 3 months.\n* Have access to a cellular phone with the ability to receive phone calls and text messages over the 12-month follow- up period\n* Adolescent must be verbally fluent and can communicate, understand, and read in either English or Spanish\n* Adolescent has been\u002Fwill be discharged from a higher level of care (i.e. inpatient, day hospital, partial hospitalization program (PHP), or residential treatment program) and back in the community within 4 weeks of their acute care visit. \\[Note: this criterion does not apply to all patients - select N\u002FA if this is the case.\n\nExclusion Criteria:\n\n* Significant cognitive or developmental delays that prevent understanding or using SPI+ or IPT-A-SCI (includes inability to communicate verbally)\n* Altered mental status (acute psychosis, intoxication, or mania)\n* Unable or unwilling to provide informed consent (adults), assent (minors), or permission (parents\u002Fcaregivers)\n* The services offered through the study are not in the best clinical interest of the patient (e.g., presenting problem requires a different level of care or treatment approach).","12 Years","24 Years",{"count":114,"type":20},1000,[23],"The study will compare the effectiveness of two relatively brief and scalable evidence-based interventions: the Stanley Brown Safety Planning Intervention and Follow-up Contacts (SPI+), a suicide-specific intervention that helps people prevent suicidal crises from escalating, and Interpersonal Psychotherapy for Adolescents Ultra Short Crisis Intervention (IPT-A SCI), a psychotherapeutic crisis intervention treatment for suicidal adolescents that teaches youth skills to prevent suicidal crises and addresses interpersonal problems that lead to suicidal crises. The results will inform the future standard of care for youth at risk for suicide presenting in the ED setting. This project focuses on suicidal youth ages 12-24 in five ethnically and racially diverse urban areas: Philadelphia, Pennsylvania; Baltimore, Maryland; Chapel Hill, North Carolina; St. Petersburg, Florida; and Northern Manhattan\u002Flower Bronx\u002Feastern Queens communities in New York City, New York.",[118,31,36,119],"Suicide, Attempted","Suicide Prevention",[121,122,123,124,119],"Safety Planning Intervention","Ultra-Brief Crisis","Interpersonal Psychotherapy for Adolescents","Emergency Department","2026-04-28",{"date":71,"type":42},{"date":128,"type":42},"2025-03-10",{"date":130,"type":20},"2028-10-14",{"name":132,"class":49},"Johns Hopkins University",6,{"id":135,"slug":136,"hasResults":11,"nctId":137,"briefTitle":138,"officialTitle":138,"acronym":4,"eligibilityCriteria":139,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":140,"targetDuration":4,"studyType":21,"phases":142,"briefSummary":143,"conditions":144,"keywords":146,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":149,"lastUpdatePostDateStruct":150,"startDateStruct":152,"completionDateStruct":154,"leadSponsor":156,"locationsCount":50},"100590448","a-one-arm-open-trial-of-a-smartphone-delivered-treatment-for-suicidal-thoughts-and-behavior-100590448","NCT06967545","A One-Arm Open Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior","Inclusion Criteria:\n\n* Adults ages 18+\n* Relatively frequent and recent (≥5 days within the past-month) active suicidal thoughts as assessed via SITBI-R.\n* Willing and able to provide at least one emergency contact (name, phone number, relation).\n* Owns an Android or iOS smartphone.\n* Possesses at least occasional access to Wi-Fi-enabled internet for data down\u002Fuploads.\n* Fluent in English and willing to provide informed consent.\n* Living in the Boston metropolitan area (i.e., \\~50 mile radius around Boston, MA)\n\nExclusion Criteria:\n\n* Recent (past 3-month) hypo\u002Fmanic symptoms or homicidal ideation or lifetime psychosis spectrum diagnosis as assessed via MINI 7.0.2.\n* Recent acute suicide risk operationalized as affirmative responses to BOTH below items during structured clinical interview AND evaluation by the PI in consultation with Mentors\u002FAdvisor Drs. Wilhelm, Kleiman, and\u002For Bentley:\n* At any time in past week: ≥ 8\u002F10 current intent to act on suicidal thoughts (0 \\[\"not at all\"\\] to 10 \\[\"extremely strong\"\\]); AND\n* At any time in past week: thought of a specific suicide plan (i.e, known method\u002Fmeans and\u002For location) with access to lethal means\n* Impaired vision (e.g., legal blindness), technological illiteracy, or intellectual disability that might impair ability to provide valid data and\u002For informed consent.",{"count":141,"type":20},20,[23],"This study aims to evaluate the acceptability, safety, and preliminary efficacy of a smartphone-delivered intervention called Therapeutic Evaluative Conditioning for Suicide (TEC-S) in reducing suicidal thoughts and behaviors (STB) among adults with recent and frequent suicide ideation.",[145,31],"Suicide Attempt",[36,147,148],"Ecological momentary assessment (EMA)","Therapeutic Evaluative Conditioning (TEC)","2026-04-15",{"date":151,"type":42},"2026-04-16",{"date":153,"type":42},"2026-01-20",{"date":155,"type":20},"2026-12-31",{"name":157,"class":49},"Massachusetts General Hospital",{"id":159,"slug":160,"hasResults":11,"nctId":161,"briefTitle":162,"officialTitle":163,"acronym":4,"eligibilityCriteria":164,"healthyVolunteers":11,"sex":16,"minAge":57,"maxAge":4,"enrollmentInfo":165,"targetDuration":4,"studyType":21,"phases":167,"briefSummary":168,"conditions":169,"keywords":173,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":178,"lastUpdatePostDateStruct":179,"startDateStruct":181,"completionDateStruct":183,"leadSponsor":185,"locationsCount":4},"100630506","engage-coaching-r33-phase-100630506","NCT07488559","Engage Coaching (R33 Phase)","Engage Coaching to Reduce Social Isolation and Loneliness to Prevent Suicide in Later Life","Inclusion criteria:\n\n* Age 60 or older\n* Access to social activities outside the home, including through living in senior living communities\n* Clinically-significant loneliness over the prior month.\n\nExclusion criteria:\n\n* Current problem drinking\n* Psychosis\n* Significant cognitive impairment\n* Hearing problems that preclude engagement with S-ENG and research assessors.",{"count":166,"type":20},120,[23],"The purpose of this study is to test whether an individual coaching program helps adults age 60 and older feel more connected to other people in ways that matter to them.",[170,171,31,172],"Social Connection","Loneliness","Social-emotional Quality of Life",[171,174,175,176,177],"Older adults","Ecological momentary assessment","Engage Psychotherapy","Late-life suicide","2026-03-23",{"date":180,"type":42},"2026-03-27",{"date":182,"type":20},"2026-05-15",{"date":184,"type":20},"2028-12-31",{"name":48,"class":49},{"id":187,"slug":188,"hasResults":11,"nctId":189,"briefTitle":190,"officialTitle":191,"acronym":192,"eligibilityCriteria":193,"healthyVolunteers":11,"sex":16,"minAge":194,"maxAge":4,"enrollmentInfo":195,"targetDuration":4,"studyType":21,"phases":197,"briefSummary":198,"conditions":199,"keywords":200,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":205,"lastUpdatePostDateStruct":206,"startDateStruct":208,"completionDateStruct":210,"leadSponsor":212,"locationsCount":50},"100543272","caring-connections-youth-suicide-detection-and-intervention-study-100543272","NCT06353711","Caring Connections Youth Suicide Detection and Intervention Study","CA-LINC Randomized Control Trial Study","CA-LINC","Inclusion Criteria:\n\nYouth:\n\n* 13 - 19 years old\n* Current or recent history (\\\u003C90 days) of suicide ideation, planning, or attempts or nonsuicidal self-injurious behaviors per youth or caregiver self-report or positive screen on the Patient Health Questionnaire Adolescent (PHQ-A), C-SSRS, or Ask Suicide-Screening Questions (ASQ).\n* Able to fluently speak and read English\n* Youth with a prior history of difficulty accessing services.\n* Written assent to participate in the study (\\\u003C18 years old)\n* Written consent from a parent\u002Flegal guardian\u002Fcaregiver to participate in the study (\\\u003C18 years old)\n* Written consent if the youth is ages 18-19\n\nParents\u002FLegal Guardians\u002FCaregivers:\n\n* The primary caregiver of a youth who meets the above inclusion criteria for the study\n* Over the age of 18\n* Able to fluently speak and read English\n* Without intellectual disabilities\n* Provide written consent to participate\n\nMental Healthcare and\u002For Healthcare Providers and\u002For Community Stakeholders:\n\n* Mental Health, behavioral health, substance use and\u002For health-related professionals who screen\u002Fassess for mental health and\u002For suicide risk or provide referrals, treatment, or follow-up care to youth with a prior history of difficulty accessing services in the surrounding treatment areas based on this risk or community stakeholder (i.e., faith-based leaders, agency directors, advocates, school administrators, hospital\u002Fcrisis directors, topical experts, etc.).\n* Over the age of 18\n* Able to fluently speak and read English\n* Without intellectual disabilities\n* Provide written consent to participate\n\nCare Coordinators:\n\n* Care coordinators who screen\u002Fassess for mental health and\u002For suicide risk or provide referrals, treatment, or follow-up care to underserved youth in the surrounding treatment areas.\n* Over the age of 18\n* Able to fluently speak and read English\n* Without intellectual disabilities\n\nExclusion Criteria:\n\nYouth:\n\n* Youth at imminent suicide risk (reported verbally and\u002For indicated on C-SSRS)\n* Youth who exhibit severe cognitive, language, or developmental delays\n* Youth not meeting inclusion criteria\n\nParents\u002FLegal Guardians\u002FCaregivers:\n\n* Not meeting the inclusion criteria listed above.\n\nMental Healthcare and\u002For Healthcare Providers and\u002For Community Stakeholders:\n\n* Not meeting the inclusion criteria listed above.","13 Years",{"count":196,"type":20},180,[23],"The goal of this pilot randomized control trial (RCT) is to test the feasibility of Caring Connections, a Culturally Adapted Linking Individuals Needing Care (CA-LINC) suicide prevention care coordination intervention for high-risk suicidal youth. This consumer-, community-, and theory-driven care coordination intervention is designed to reduce suicide ideation and behavior (SIB) by improving service engagement. Connections is a 90-day intervention that integrates engagement and follow-up strategies to assess\u002Fmonitor suicide risk, facilitate service use referrals\u002Flinkages, develop\u002Frefine safety plans, and create villages of care. The intervention incorporates cultural promotive factors, empowerment, and motivational strategies aimed at supporting youth, enhancing strengths, promoting hope, improving family relationships, and reinforcing caring messages. Primary research questions include:\n\nIs Caring Connections feasible to use for suicidal high-risk youth? Does Caring Connections have the potential to reduce suicide ideation and behaviors among high-risk suicidal youth?\n\nFor the pilot RCT, 80 youth participants ages 13-19 who meet the inclusion criteria will be randomly assigned to one of two conditions: Caring Connections (n=40) or Treatment as Usual (n=40). Additionally, investigators will enroll 80 caregivers of youth meeting inclusion criteria and 20 Mental Healthcare, Healthcare Providers, Community Stakeholders, and\u002For Care Coordinators with experience working with suicidal youth. Researchers will compare those receiving Caring Connections with treatment as usual to see if suicidal ideation and behaviors, and engagement.",[36,119,31,145],[201,202,203,204],"Black youth","suicide","ideation","attempts","2026-03-13",{"date":207,"type":42},"2026-03-17",{"date":209,"type":42},"2025-08-14",{"date":211,"type":20},"2026-10",{"name":213,"class":49},"University of North Carolina, Chapel Hill",{"id":215,"slug":216,"hasResults":11,"nctId":217,"briefTitle":218,"officialTitle":219,"acronym":220,"eligibilityCriteria":221,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":222,"targetDuration":4,"studyType":21,"phases":224,"briefSummary":225,"conditions":226,"keywords":227,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":232,"lastUpdatePostDateStruct":233,"startDateStruct":235,"completionDateStruct":237,"leadSponsor":239,"locationsCount":50},"100545180","smartphone-app-enhanced-facilitation-among-veterans-in-a-mental-health-inpatient-setting-project-hope-100545180","NCT06378541","Smartphone App Enhanced Facilitation Among Veterans in a Mental Health Inpatient Setting (Project HOPE)","Virtual Hope Box Enhanced Facilitation in High-Risk Suicidal Veterans","Project HOPE","Inclusion Criteria:\n\nThose enrolled in the RCT component of this study must be:\n\n* 1\\) Veterans aged 18 or older\n* 2\\) admitted to the inpatient psychiatric unit for a recent suicidal crisis\n* 3\\) medically stable (the patient's medical and psychological fitness \\[including aggression\\] to provide informed consent will be determined by a member of the patient's treatment team)\n* 4\\) A score of 3 or greater on the Callahan 6-item cognitive screening.\n* 5\\) report current suicidal ideation (Scale for Suicidal Ideation \\[SSI\\]; sum of items 4 and 5 \\> 0, referencing the week prior to their hospitalization) as reported during the screening interview\n* 6\\) no reported use of the VHB within the past 12-months\n* 7\\) access to a smartphone to download the VHB app\n\nExclusion Criteria:\n\nVeterans will be found ineligible for the program if:\n\n* 1\\) do not understand English\n* 2\\) are prisoners\n* 3\\) are unable to provide informed consent\n* 4\\) have profound psychotic symptoms and\u002For cognitive deficits that would prevent patients from understanding the content of the intervention and\u002For assessments\n* 5\\) to not have access to a smartphone",{"count":223,"type":20},928,[23],"This study will test whether a novel intervention, Virtual Hope Box Enhanced Facilitation (VHB-EF), reduces suicide risk in Veterans after discharge from inpatient psychiatric hospitalization. Additionally, this study will also conduct interviews with Veterans and healthcare providers to explore barriers and facilitators to future adoption of the VHB-EF intervention in healthcare settings.",[119,145,31],[228,229,230,231],"smartphone application","suicide prevention","virtual hope box","veterans","2026-02-04",{"date":234,"type":42},"2026-02-09",{"date":236,"type":42},"2025-03-26",{"date":238,"type":20},"2029-05-31",{"name":240,"class":241},"VA Office of Research and Development","FED",{"id":243,"slug":244,"hasResults":11,"nctId":245,"briefTitle":246,"officialTitle":247,"acronym":4,"eligibilityCriteria":248,"healthyVolunteers":11,"sex":16,"minAge":111,"maxAge":249,"enrollmentInfo":250,"targetDuration":4,"studyType":21,"phases":252,"briefSummary":253,"conditions":254,"keywords":255,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":260,"lastUpdatePostDateStruct":261,"startDateStruct":263,"completionDateStruct":265,"leadSponsor":267,"locationsCount":269},"100617965","plan-and-protect-safety-planning-for-teens-in-rural-emergency-departments-100617965","NCT07325474","Plan and Protect: Safety Planning for Teens in Rural Emergency Departments","Development & Implementation of Culturally Sensitive Safety Planning to Reduce Suicide Risk in Adolescents Seeking Care in Rural Emergency Departments","Inclusion criteria for children:\n\n* 12-17 years of age (and their parent\u002Fcaregiver(s))\n* Ability to speak and complete surveys in English\n* History of emergency department visit for suicidality, self-harm or mental health crisis\n* Medically stable\n\nExclusion criteria for children:\n\n* Cognitive or developmental delays that preclude program participation based on clinical team assessment\n* Diagnosis of psychosis\n* Primary diagnosis of an eating disorder\n* Parent\u002Fguardian not able to provide consent in English\n* Clinical team concern for patient or staff safety based upon active behavioral concerns\n* Parent\u002Fguardian not available to provide consent (e.g youth is in child protective custody\u002Fward of the state)\n\nInclusion criteria for parents\u002Fcaregivers:\n\n* Parent or caregiver of an eligible child\n* 18 years old or older\n* Ability to speak and complete surveys in English\n\nExclusion criteria for parents\u002Fcaregivers:\n\n-Inability to understand key aspects of the study","17 Years",{"count":251,"type":20},550,[23],"The goal of this observational study is to determine whether implementing a culturally sensitive, tablet-based safety planning program called Plan \\& Protect (P\\&P) within rural emergency departments can improve home safety and reduce suicide risk in adolescents presenting with suicidality.\n\nThe main questions it aims to answer are:\n\n* Will implementing P\\&P increase caregiver-reported home safety (reduce access to firearms and unsafe medication storage) for adolescents 12-17 years old presenting to rural EDs with suicidal ideation, self-harm, or mental health crisis?\n* Will implementing P\\&P decrease adolescent-reported perceived suicide risk and related outcomes (e.g., suicide events, and attendance at follow-up mental healthcare)?\n\nResearchers will compare outcomes for adolescents and caregivers receiving P\\&P (implemented as the new standard of care at sites during the intervention periods) to those receiving usual care (prior to P\\&P implementation at those hospitals) to see if P\\&P increases home safety and decreases suicide risk and related healthcare utilization.\n\nParticipants will, if clinically appropriate:\n\n* Complete the tablet-based P\\&P modules during their ED visit\n* Complete self-report measures at baseline, \\~30 days, and \\~3 months post-discharge\n* A subset will also participate in semi-structured interviews",[31,145],[36,256,257,258,259],"Safety Planning","Adolescent","Mental Health Services","Emergency Services","2026-01-27",{"date":262,"type":42},"2026-01-29",{"date":264,"type":20},"2026-06-01",{"date":266,"type":20},"2028-09-30",{"name":268,"class":49},"Dartmouth-Hitchcock Medical Center",4,{"id":271,"slug":272,"hasResults":11,"nctId":273,"briefTitle":274,"officialTitle":275,"acronym":276,"eligibilityCriteria":277,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":278,"targetDuration":4,"studyType":21,"phases":280,"briefSummary":281,"conditions":282,"keywords":4,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":288,"lastUpdatePostDateStruct":289,"startDateStruct":291,"completionDateStruct":293,"leadSponsor":295,"locationsCount":50},"100536352","differences-between-suicide-attempters-and-suicide-ideators-influence-of-the-brief-therapy-attempted-suicide-short-intervention-program-assip-on-neuropsychological-correlates-and-psychological-process-factors---project-2-100536352","NCT06263712","Differences Between Suicide Attempters and Suicide Ideators. Influence of the Brief Therapy Attempted Suicide Short Intervention Program (ASSIP) on Neuropsychological Correlates and Psychological Process Factors - Project 2","Differences Between Suicide Attempters and Suicide Ideators. Influence of the Brief Therapy ASSIP on Neuropsychological Correlates and Psychological Process Factors (NePsyASSIP HT) - Project 2","NePsyAssip HT","Inclusion Criteria for Project 2:\n\nSubjects fulfilling the following inclusion criteria are eligible for the study:\n\n* Informed consent as documented by signature\n* Age ≥ 18 years\n* At least one previous suicide attempt\n* Willingness to attend the ASSIP brief therapy\n* Owns a smartphone\n\nExclusion Criteria for Project 2:\n\nThe presence of any one of the following exclusion criteria will lead to exclusion of the subject:\n\n* Serious cognitive impairment\n* Any psychotic disorder\n* Any current medication, which substantially impairs the attention span, reaction, rate or any other relevant cognitive functions\n* Inability to follow the procedures of the study (e.g., insufficient mastery of the German language, previous enrolment into the current study)",{"count":279,"type":20},156,[23],"The present study consists of 3 projects in total and aims to investigate the (neuro-) psychological patterns from suicidal ideation to suicidal behavior as well as the effects and feasibility of ASSIP Home Treatment.\n\nThe overall aim of project 2 is to investigate how the (neuro-) psychological patterns are modulated by the Attempted Suicide Short Intervention Program (ASSIP). Therefore, suicide attempters participating in this project 2 will be randomly assigned to either the intervention group ASSIP or a standard care plus resource interview (STAR) group. The ASSIP and STAR interventions take place at the University Hospital of Psychiatry and Psychotherapy Bern (Switzerland).\n\nAt the end of the assessment in project 1 participants who reported a history of past suicide attempt (SUAT) will be informed about project 2.\n\nOnly if participants agreed to take part in project 2 and have signed the informed consent, they are randomized into two conditions: The ASSIP intervention (ASSIP) versus standard of care plus resource interview (STAR). Participants of both groups will be assessed again 4 weeks and 12 months after their first baseline assessment of project 1.",[283,284,31,118,285,286,287],"Inhibitory Control","Self Efficacy","Locus of Control","Process Factors","Movement Synchrony","2026-01-19",{"date":290,"type":42},"2026-01-22",{"date":292,"type":42},"2024-03-25",{"date":294,"type":20},"2026-12",{"name":296,"class":49},"University of Bern",{"id":298,"slug":299,"hasResults":11,"nctId":300,"briefTitle":301,"officialTitle":302,"acronym":303,"eligibilityCriteria":304,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":305,"targetDuration":307,"studyType":308,"phases":4,"briefSummary":309,"conditions":310,"keywords":312,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":318,"lastUpdatePostDateStruct":319,"startDateStruct":321,"completionDateStruct":323,"leadSponsor":325,"locationsCount":50},"100614795","suicidal-ideation-framework-grounded-theory-study-catalonia-100614795","NCT07284238","Suicidal Ideation Framework: Grounded Theory Study, Catalonia","Process of Configuring the Suicidal Ideation Framework: A Grounded Theory Study in Catalonia, Spain","SUIF-GT-CAT","Inclusion Criteria:\n\n* Adults ≥18 years of age.\n* Usual residence in Catalonia (Spain).\n* Ability to understand, speak, read, and write in Catalan or Spanish.\n* Belonging to one of the three defined analytical groups:\n\n(A) Individuals who have attempted suicide within the past 6 months to 3 years. (B) Members of their family, social, or community support networks. (C) Healthcare professionals directly involved in the care of individuals who have attempted suicide.\n\n* Demonstrated clinical\u002Femotional stability ensuring safe participation, as confirmed by the referring clinician.\n* For individuals with lived experience (Group A): at least 6 months since the last suicide attempt or acute clinical crisis.\n* For support networks (Group B): having maintained meaningful proximity or involvement during or after the suicide attempt.\n* For healthcare professionals (Group C): minimum of 1 year of professional experience in mental health care.\n\nExclusion Criteria:\n\n* Presence of acute clinical decompensation preventing safe participation.\n* Active suicidal risk or acute crisis at the time of recruitment.\n* Acute vulnerability identified during screening.\n* Inability to provide informed consent.\n* Direct hierarchical dependence or conflict of interest with the research team (for Group C).",{"count":306,"type":20},45,"1 Day","OBSERVATIONAL","This doctoral project aims to develop a comprehensive theoretical model of the process through which the suicidal ideation framework is configured as a symbolic, narrative, and relational expression, adopting a multiperspective approach that spans the suicide attempt and the stages of care and recovery. Moving away from biomedical reductionisms, this investigation seeks to identify shared meaning-making nuclei and discursive fractures that reflect the inherent conflictuality of the suicidal act.\n\nGrounded in the integration of the theoretical frameworks previously outlined, this study adopts an interpretive-constructivist approach. Phase 1 will include studies conducted in OECD countries, providing a broad and conceptually diverse interpretive foundation. Phase 2, conducted in Catalonia, will deepen situated configurations, assuming that local sociocultural frameworks act as interpretive prisms for globally relevant phenomena.\n\nOverall, this theoretical-methodological architecture not only ensures conceptual robustness and coherence, but also articulates an ethical and epistemic commitment to understanding suicide through the complexity of its human textures. By centering suffering, listening to historically silenced voices, honoring the singularity of each life trajectory, and grounding the inquiry in an ethics of care, this study aims to transcend a merely technical-instrumental logic of knowledge.",[36,145,31,311,119],"Suicide Risk",[313,36,314,315,316,317],"Suicidal Ideation","Meta-synthesis","Grounded Theory","Mental Health Nursing","High-Income Countries","2025-12-02",{"date":320,"type":42},"2025-12-16",{"date":322,"type":20},"2026-03",{"date":324,"type":20},"2027-09",{"name":326,"class":49},"Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau",{"id":328,"slug":329,"hasResults":11,"nctId":330,"briefTitle":331,"officialTitle":332,"acronym":4,"eligibilityCriteria":333,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":334,"targetDuration":4,"studyType":21,"phases":336,"briefSummary":337,"conditions":338,"keywords":339,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":346,"lastUpdatePostDateStruct":347,"startDateStruct":349,"completionDateStruct":351,"leadSponsor":353,"locationsCount":50},"100603098","randomized-suicide-prevention-trial-using-assip-and-act-in-suicide-attempters-100603098","NCT07132099","Randomized Suicide Prevention Trial Using ASSIP and ACT in Suicide Attempters","RCT Comparing ASSIP and ACT on Mental Pain and Suicidal Ideation in Individuals With Suicide Attempts","Inclusion Criteria:\n\n* Being 18 years of age or older\n* Having the ability to read and write\n* Providing informed consent to participate in the study\n* Having at least one suicide attempt in the past 4 months\n\nExclusion Criteria:\n\n* Having a severe psychiatric or physical illness that interferes with the treatment process\n* Receiving concurrent structured psychological interventions (other than TAU) that may interfere with the study's treatment process.\n* Lack of informed consent to participate in the study\n* Substance abuse based on DSM-5 criteria",{"count":335,"type":20},60,[23],"This is a randomized controlled trial that aims to compare the effectiveness of two psychological treatment approaches: the Attempted Suicide Short Intervention Program (ASSIP) and Acceptance and Commitment Therapy (ACT). The study seeks to determine which of these two methods is more effective in reducing suicidal ideation and mental pain in individuals who have recently attempted suicide.\n\nIn this study, 60 participants with a history of suicide attempts will be randomly assigned to three groups. One group will receive ASSIP in addition to treatment as usual (TAU), the second group will receive ACT alongside TAU, and the third group will be a control group receiving TAU only. The results will be assessed using the Beck Scale for Suicide Ideation (BSSI) and the Orbach \\& Mikulincer Mental Pain Scale (OMMP) at three stages: pre-test, post-test, and follow-up.\n\nThe ultimate goal of this research is to provide valuable insights into the comparative effectiveness of ASSIP and ACT interventions for suicide attempters and to contribute to evidence-based suicide prevention strategies. The findings are expected to inform clinical practice and guide future research in this field.",[36,31],[340,341,313,342,343,344,345],"Attempted Suicide Short Intervention Program","Acceptance and Commitment Therapy","Mental Pain","Suicide attempt","ASSIP","ACT","2025-08-18",{"date":348,"type":42},"2025-08-20",{"date":350,"type":42},"2025-08-01",{"date":352,"type":20},"2025-10",{"name":354,"class":49},"Ardakan University",{"id":356,"slug":357,"hasResults":11,"nctId":358,"briefTitle":359,"officialTitle":360,"acronym":4,"eligibilityCriteria":361,"healthyVolunteers":11,"sex":16,"minAge":111,"maxAge":17,"enrollmentInfo":362,"targetDuration":4,"studyType":21,"phases":363,"briefSummary":364,"conditions":365,"keywords":367,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":377,"lastUpdatePostDateStruct":378,"startDateStruct":380,"completionDateStruct":382,"leadSponsor":384,"locationsCount":50},"100583935","a-new-clinical-model-for-the-engagement-of-latinx-youth-with-suicidal-behavior-100583935","NCT06882798","A New Clinical Model for the Engagement of Latinx Youth With Suicidal Behavior","A New Clinical Model for the Engagement of Latinx Youth With Suicidal Behavior and Their Families in a Culturally Centered CBT Treatment","Inclusion Criteria:\n\n* Latinx, defined as have been born in a Latin country or having at least one biological parent, grandparent or an ancestor that was born in a Latin country\n* Severe Suicidal Ideation (SI), defined as one of the following:\n* SIQ-JR \\> 22 or endorsing any critical items (2, 3, 4, 7, 8, 9) with at least \"about 1x\u002Fmonth\"\n* CDI-II \\> 15 and endorsing \"I think about killing myself but would not do it\" OR \"I think about killing myself.\"\n* PHQ-9 \\> 10 \\& endorsing the item \"Thoughts that you would be better off dead, or of hurting yourself in some way\" with a frequency of \"several days\" or greater or endorsing the item \"Has there been a time in the past month when you have had serious thoughts about ending your life?\n* Suicidal crisis within the past 12 months\n* Caregivers and adolescents fluent in Spanish or English language and legal guardian willing to participate\n\nExclusion Criteria:\n\n* Participants will be referred to a different treatment program if their main clinical complaint is any of the following:\n* Behavioral (e.g., conduct disorder, or substance use disorder)\n* An eating disorder\n* Obsessive-compulsive disorder\n* A developmental issue (e.g., speech, occupational, families looking for assessments, treatment for autism) or a significant cognitive delay that may require specialized treatment adjustments.",{"count":59,"type":20},[23],"This study will test a model of providing treatment to Latinx\u002FHispanic youth, who experience suicidal thoughts and behavior, and their caregivers. An affirmative and culturally relevant treatment will be provided to all youth and half of the families will be assigned to the additional support of a community health worker (CHW). Youth symptoms and family engagement to treatment will be followed for nine months. The potential benefit of adding the CHW intervention will be assessed.",[31,91,366],"Depressive Symptoms",[313,145,368,369,370,371,372,373,374,375,376],"Randomized controlled trial","adolescents","Latinx","Latina","Latino","Hispanic","cognitive behavioral therapy","depressive symptoms","community health workers","2025-03-17",{"date":379,"type":42},"2025-03-19",{"date":381,"type":42},"2024-03-28",{"date":383,"type":20},"2027-01",{"name":385,"class":49},"Bradley Hospital",{"id":387,"slug":388,"hasResults":11,"nctId":389,"briefTitle":390,"officialTitle":391,"acronym":392,"eligibilityCriteria":393,"healthyVolunteers":11,"sex":16,"minAge":194,"maxAge":249,"enrollmentInfo":394,"targetDuration":4,"studyType":21,"phases":396,"briefSummary":397,"conditions":398,"keywords":399,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":403,"lastUpdatePostDateStruct":404,"startDateStruct":406,"completionDateStruct":408,"leadSponsor":410,"locationsCount":50},"100582830","electronic-self-guided-safety-plan-in-adolescents-project-safer-100582830","NCT06868407","Electronic, Self-Guided Safety Plan in Adolescents: Project SAFER","Randomized Control Trial of Electronic, Self-Guided Safety Plan in Adolescents: Project SAFER","Project SAFER","Inclusion Criteria:\n\n* Able to read and write in English\n* Internet access,\n* Past-month suicidal thoughts AND a past-year suicide attempt OR at least 5 days of suicidal thoughts in the past year.\n\nExclusion Criteria:\n\n* disability that interferes with the ability to complete the study on a computer\n* not in US\n* response that indicates bot or fraudulent",{"count":395,"type":20},300,[23],"Suicide is a leading cause of death for youth 10-24, and nearly ¼ of adolescents report nonfatal suicidal thoughts and behaviors (STB). However, traditional interventions (e.g., multi-session therapy protocols) are contingent upon (1) access to treatment, (2) involvement of parents\u002Fguardians (hereafter parents), and (3) disclosure of risk to treatment providers. Unfortunately, adolescents are frequently hesitant to disclose STB to healthcare providers and parents for reasons including shame, stigma, and fear of hospitalization, with even lower rates of disclosure among queer youth-including those with diverse genders and sexualities- who are at disproportionately high risk for STB. Related to these concerns, most youth at risk for suicide, as well as other mental health challenges, do not access any mental healthcare. Self-guided, brief digital interventions may be a powerful adolescent suicide prevention tool. With their relative accessibility-they can be completed privately, at home, for at no cost-such interventions are well-suited for youth not accessing traditional care. Thus, effective digital adaptation of brief suicide prevention interventions is a promising frontier for adolescent suicide prevention.\n\nA strong candidate for digital adaptation is the Safety Planning Intervention (SPI), a brief (\\~5-10 minute) single-session intervention shown to significantly reduce STB in adults. In the SPI, people at risk for suicide receive brief education about suicidal thoughts and crises before developing a personalized, one-page plan with skills and resources to use during future suicide crises, when it is difficult to think clearly. There is strong evidence across several randomized control trials (RCTs) that SPI reduce suicidal behaviors in adults compared to those who received treatment as usual. Despite widespread use in outpatient and acute clinical settings across ages, there is a paucity of adequately-powered RCTs testing whether the SPI (in any format) reduces STB in adolescents.\n\nEmerging evidence supports the SPI can work well in digital format among adolescents. In qualitative studies, adolescents with a history of STBs reported that they would be comfortable using a digital safety plan and feel it would be helpful to them in a crisis, emphasizing easy access and customizability as useful features. Building on this work, I created a digital, self-guided SPI specifically for use in online studies of high-risk adolescents. Preliminary research (approved by DU IRB# 1505797) suggests that youth find this self-guided digital SPI \"very helpful\" and nearly half actually use the safety plan in the next month. Moreover, using a standardized coding system, quality of self-guided safety plans mirrored the quality seen in clinician-guided, adult SPI. However, it remains unclear whether the SPI in any format can reduce STB in adolescents.\n\nThis project will test the ability of a self-guided SPI, compared to a suicide psychoeducational control intervention, to increase self-efficacy to avoid suicidal behaviors and to reduce suicidal thoughts and suicidal behaviors in adolescents over a 3-month follow-up period. The investigators hypothesize that compared to the control condition, adolescents who receive the SPI will report greater self-efficacy to avoid suicidal action and reduced STB at the 3-month follow-up assessment. If hypotheses are supported, this study will provide strong, high-quality evidence in favor of the potential of highly accessible, digital self-guided SPIs to prevent suicidal behavior in adolescents. In this case, distribution of such an intervention at scale could be a powerful tool for reducing STBs in adolescents.",[145,31],[400,202,401,402],"adolescent","safety plan intervention","RCT","2025-03-06",{"date":405,"type":42},"2025-03-11",{"date":407,"type":20},"2025-03-08",{"date":409,"type":20},"2025-08-05",{"name":411,"class":49},"University of Denver","Suicide, Ideation"]