[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"suicide-prevention\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:suicide-prevention":27},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,42,0,25,[9,44,70,106,131,153,175,197,222,248,276,300,320,343,362,385,419,447,476,505,532,558,583,608,631],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100602205","phase-4-esketamine-versus-crisis-response-planning-versus-optimized-treatment-as-usual-for-suicide-prevention-a-pragmatic-controlled-trial-in-two-brazilian-cities-100602205",false,"NCT07120477","Esketamine Versus Crisis Response Planning Versus Optimized Treatment as Usual for Suicide Prevention: A Pragmatic Controlled Trial in Two Brazilian Cities","SAVE","Inclusion Criteria:\n\n1. Age 14 years or older\n2. Presentation to a public emergency service (ED\u002FUEU) within the study municipality\n3. Recent suicide attempt within the past 30 days (actual, interrupted, or aborted attempt)\n4. Current severe suicidal ideation, defined as endorsement of items 4 or 5 on the Columbia-Suicide Severity Rating Scale (C-SSRS) screening version, indicating active suicidal ideation with specific plan and\u002For method, or active suicidal ideation with intent to act\n5. Residency in the catchment area of the study municipality (Indaiatuba, São Paulo, Brazil), enabling completion of follow-up assessments\n6. Ability to provide written informed consent (for participants aged 18 years or older) or written assent with written informed consent from a parent or legal guardian (for participants aged 14-17 years)\n7. No clinical decision for involuntary or voluntary hospitalization in a psychiatric inpatient unit following the index emergency department evaluation\n\nExclusion Criteria:\n\n1. Contraindications to esketamine, including: aneurysmal vascular disease, arteriovenous malformation, history of intracerebral hemorrhage, or known hypersensitivity to esketamine or ketamine\n2. Current pregnancy or breastfeeding (confirmed by rapid pregnancy test in the emergency setting for female participants of childbearing potential)\n3. Medical instability requiring intensive care unit (ICU) admission without feasible study follow-up\n4. Primary psychotic disorder (e.g., schizophrenia, schizoaffective disorder), current acute psychosis, or current acute manic episode precluding informed participation\n5. Severe substance use disorder compromising capacity for treatment adherence, as assessed by the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST)\n6. Inability to maintain contact for follow-up assessments, including participants whose residential address is located outside the study municipality","ALL","14 Years",{"count":20,"type":21},468,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","Suicide is one of the leading causes of early death worldwide. In Brazil, suicide rates have been rising steadily over the past two decades, and most suicides occur in low- and middle-income countries where access to specialized care is limited. There is an urgent need for fast-acting, practical interventions that can be delivered in public emergency settings. Two promising approaches have emerged: esketamine, a medication that can rapidly reduce suicidal thoughts within hours, and Crisis Response Planning (CRP), a brief session in which a trained clinician works with the person to create a personalized written plan for managing future suicidal crises.\n\nThe goal of this clinical trial is to learn if esketamine or Crisis Response Planning (CRP), each added to enhanced treatment as usual (eTAU), can prevent future suicide-related events compared to eTAU alone in adolescents and adults aged 14 years or older who recently attempted suicide or have severe suicidal thoughts. The main questions it aims to answer are:\n\nDoes a single esketamine infusion plus eTAU lower the risk of a new suicide-related event compared to eTAU alone over 12 months? Does a single session of Crisis Response Planning plus eTAU lower the risk of a new suicide-related event compared to eTAU alone over 12 months? Which approach leads to faster or more lasting improvements in suicidal thoughts, depression, anxiety, sleep, well-being, hopelessness, and quality of life? Are these interventions feasible, acceptable, and cost-effective within a public health system?\n\nResearchers will compare three groups to see which approach works best to prevent suicide attempts, suicide-related hospitalizations, and suicide deaths over one year.\n\nA total of 468 participants will be randomly assigned in equal numbers (156 per group) to one of three groups:\n\nEsketamine group: receive a single intravenous esketamine infusion (0.50 mg\u002Fkg given over 40 minutes) in a monitored medical setting with continuous heart rate, blood pressure, and oxygen monitoring, plus eTAU. A physician will be present throughout. Participants will be observed for up to 24 hours before discharge.\n\nCrisis Response Planning group: complete one 20-to-45-minute session with a trained clinician to build a personal crisis plan that includes warning signs, coping strategies, reasons for living, support contacts, and emergency resources. Participants will leave with a written and digital copy of their plan, plus eTAU.\n\nEnhanced treatment as usual (eTAU) group: receive standard emergency care, safety counseling about access to lethal means, connection to the local mental health network (including Psychosocial Care Centers and primary care), and a scheduled psychiatric follow-up appointment within 7 days.\n\nParticipants will:\n\nComplete health questionnaires about suicidal thoughts, depression, anxiety, sleep, well-being, hopelessness, and quality of life at 11 time points over one year (at enrollment, 24 hours, 7 days, 2 weeks, 4 weeks, 8 weeks, 16 weeks, 24 weeks, 32 weeks, 40 weeks, and 1 year) Provide a blood sample at the start of the study for exploratory analyses of biological markers that may be related to treatment response Use a smartphone app to report their mood, thoughts, and emotions four times a day for four weeks after enrollment Be monitored for safety and adverse events throughout the entire study period\n\nThe study takes place in the public emergency network of Indaiatuba, São Paulo, Brazil (population approximately 256,000), and is designed to reflect real-world clinical conditions. Participants who experience a new suicide-related event during the study will be offered an open-label rescue treatment combining esketamine and Crisis Response Planning, and will continue to be followed for the remainder of the year. The study also includes an evaluation of how well these interventions can be adopted and sustained within Brazil's public mental health system, including assessments of acceptability, feasibility, and cost-effectiveness.",[27,28,29],"Suicide Prevention","Ketamine","Crisis Response Plan",[27,28,29],"RECRUITING","2026-06-28",{"date":34,"type":35},"2026-06-30","ACTUAL",{"date":37,"type":35},"2026-06-01",{"date":39,"type":21},"2029-12",{"name":41,"class":42},"University of Sao Paulo","OTHER",1,{"id":45,"slug":46,"hasResults":12,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":12,"sex":17,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":43},"100645259","peer-delivered-youth-suicide-prevention-in-nepal-100645259","NCT07680179","Peer Delivered Youth Suicide Prevention in Nepal","Innovations for Peer-delivered and Family-engaged Brief Interventions for Youth Suicide in Nepal: A Pilot Hybrid Type 2 Implementation Study","Inclusion Criteria:\n\nPeer Volunteers\n\n* Age ≥18 years\n* No current untreated mental disorder or suicide risk, as assessed and confirmed by a Nepali mental health specialist (MD or PhD)\n* Meets hiring and eligibility criteria of the local implementing partner NGO\n* Fluent in spoken Nepali\n\nTrial Youth Patient Participants\n\n* Age 12-24 years\n* Resident of the study site\n* Screens positive to the Nepali Ask Suicide Screening Questions or a lifetime history of a suicide attempt\n* Ability to provide informed consent or assent\n* For participants under 18 years of age, written informed consent from a legal guardian\n* Fluent in Nepali\n\nFamily Members (intervention group only)\n\n* Family member (defined as any individual that is a parent, grandparent, aunt\u002Funcle, or cousin as well as significant others) selected by the youth participants enrolled in the study\n* Resident of the study site\n* Over 18 years of age\n* Ability to provide informed consent or assent\n* Fluent in Nepali\n\nExclusion Criteria:\n\nPeer Volunteers\n\n* Plans to leave the peer volunteer role within the next 6 months\n* Unable to provide voluntary informed consent for any reason\n\nTrial Youth Patient Participants\n\n* Requires immediate psychiatric hospitalization at the time of assessment\n* Unable to provide informed consent or assent due to impaired decision-making capacity\n* Participants under 18 years of age without written informed consent from a legal guardian\n* Planning to leave the study area in the next 6 months\n\nFamily Members\n\n* Requires immediate psychiatric hospitalization at the time of assessment\n* Unable to provide informed consent or assent due to impaired decision-making capacity\n* Planning to leave the study area in the next 6 months","12 Years","24 Years",{"count":54,"type":21},160,[56],"NA","South Asia has the highest suicide rate in the world with important risk profile differences from high-income settings. Investigators will conduct formative research to co-design a package of brief interventions and implementation strategies to prevent youth-suicide and then test the package in a pilot feasibility hybrid type 2 cluster randomized controlled trial in Nepal. Potential health impacts may be substantial as results can be applied not only in similar South Asian primary healthcare contexts, but also in low-resource settings in the US and abroad, where the suicide burden remains high.\n\nUsing experience-based co-design and equity-focused implementation frameworks, this study will assess the feasibility and acceptability of a Youth-focused, Peer-delivered, Family-engaged Suicide Prevention Package (YPF-SuPP) integrated within existing mhGAP services in Nepal's decentralized primary healthcare system. This pilot trial will generate preliminary data to inform the design of a future fully powered effectiveness trial and potential scale-up of youth suicide prevention strategies.",[59,27],"Suicide","NOT_YET_RECRUITING","2026-06-25",{"date":63,"type":35},"2026-07-02",{"date":65,"type":21},"2026-06",{"date":67,"type":21},"2028-06",{"name":69,"class":42},"Yale University",{"id":71,"slug":72,"hasResults":12,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":4,"eligibilityCriteria":76,"healthyVolunteers":77,"sex":17,"minAge":78,"maxAge":4,"enrollmentInfo":79,"targetDuration":4,"studyType":22,"phases":81,"briefSummary":82,"conditions":83,"keywords":89,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":43},"100609805","virtual-reality-lethal-means-safety-training-100609805","NCT07219355","Virtual Reality Lethal Means Safety Training","Expanding Provider Capacity to Prevent Rural Veteran Suicide: Virtual Reality Lethal Means Safety Training","Inclusion Criteria:\n\n* Age 18 or older\n* healthcare providers serving rural Veterans in Texas (e.g., physicians, physician assistants, nurse practitioners, nurses, pharmacists, social workers, healthcare case managers)\n* English-speaking\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Self-reported pregnancy\n* History of motor or balance disorders\n* Color blindness\n* Neurological or cognitive disorders\n* Cardiovascular issues that may be worsened by VR use\n* Use of cardiac pacemakers, defibrillators, or hearing aids incompatible with VR equipment\n* Significant discomfort in virtual reality environments (e.g., severe motion sickness, vertigo)",true,"18 Years",{"count":80,"type":21},36,[56],"The goal of this randomized clinical trial is to determine whether a virtual reality (VR) training program can help healthcare providers improve their skills in discussing suicide prevention and safe storage of firearms and medications with Veterans. The study will test whether VR training increases providers' self-efficacy, confidence, and comfort in conducting lethal means safety counseling, and whether it improves their intention to use these counseling practices in their clinical work. Researchers will compare healthcare providers who complete the VR training to those who complete a 2D video training to determine whether the VR approach is more effective. Participants will complete online surveys before and after the training and again three months later. They will be randomly assigned to one of two groups: VR training group: Participants use a VR headset to interact with a virtual Veteran patient in a simulated rural clinic and practice suicide prevention counseling skills; Video training group: Participants use the same headset to watch a \\~10-minute 2D video depicting the lethal means safety counseling session. After the training, participants will also provide feedback about their experience, including how realistic and useful they found the training.",[84,85,27,86,87,88],"Suicide, Attempted","Suicide, Completed","Mental Health Training","Rural Health","Veterans",[88,90,27,91,92,93,94,95,96,87],"Rural Veterans","Suicide Risk","Firearm Safety","Medication Safety","Lethal Means Safety Counseling","Virtual Reality (VR)","VR Training Simulation","2026-06-23",{"date":99,"type":35},"2026-06-24",{"date":101,"type":35},"2026-02-23",{"date":103,"type":21},"2026-09-30",{"name":105,"class":42},"The University of Texas at Arlington",{"id":107,"slug":108,"hasResults":12,"nctId":109,"briefTitle":110,"officialTitle":111,"acronym":4,"eligibilityCriteria":112,"healthyVolunteers":12,"sex":17,"minAge":51,"maxAge":113,"enrollmentInfo":114,"targetDuration":4,"studyType":22,"phases":116,"briefSummary":117,"conditions":118,"keywords":119,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":127,"leadSponsor":129,"locationsCount":43},"100596308","caring-contacts-via-text-message-for-suicidal-adolescents-after-emergency-department-discharge-100596308","NCT07043764","Caring Contacts Via Text Message for Suicidal Adolescents After Emergency Department Discharge","Caring Texts for Adolescents to Reduce Suicide Risk","Inclusion Criteria:\n\n* 12 to \\\u003C18 years of age\n* Present to the emergency department with suicidal thoughts or behaviors as indicated by the Ask Suicide-Screening Questions (ASQ)\n* Have a cell phone that can receive text messages\n* Proficient in English\n* Anticipated disposition of discharge from the emergency department\n\nExclusion Criteria:\n\n* In care of the Department of Children and Family Services\n* Unable to participate meaningfully in assent, assessments, or the intervention, as determined by the treating clinician, including any of the following: acute or chronic cognitive impairment, acute psychosis, current severe agitation, current alcohol or drug intoxication","17 Years",{"count":115,"type":21},56,[56],"The goal of this pilot clinical trial is to learn if Caring Contacts (brief, hopeful, supportive text messages) can be delivered to adolescents with suicidal thoughts or behaviors after discharge from the emergency department, and to understand if adolescents find it acceptable to receive Caring Contacts. Researchers will also begin to explore how suicidal thoughts and behaviors change over time among participants who receive Caring Contacts along with treatment as usual, compared to participants who only receive treatment as usual.\n\nAll participants will be invited to answer survey questions when they first enroll in the study and 1, 3, 6, and 12 months after their emergency department visit. Some participants will receive Caring Contacts (brief, hopeful, supportive text messages) after their emergency department visit. Some participants will be invited to complete an interview about their experiences receiving Caring Contacts.",[27],[120,121],"Adolescent","Text Messaging","2026-06-16",{"date":124,"type":35},"2026-06-18",{"date":126,"type":21},"2026-07",{"date":128,"type":21},"2028-08",{"name":130,"class":42},"Ann & Robert H Lurie Children's Hospital of Chicago",{"id":132,"slug":133,"hasResults":12,"nctId":134,"briefTitle":135,"officialTitle":136,"acronym":4,"eligibilityCriteria":137,"healthyVolunteers":77,"sex":17,"minAge":78,"maxAge":4,"enrollmentInfo":138,"targetDuration":4,"studyType":140,"phases":4,"briefSummary":141,"conditions":142,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":148,"completionDateStruct":149,"leadSponsor":151,"locationsCount":43},"100642300","user-evaluation-think-life-100642300","NCT07654127","User Evaluation Think Life","Evaluation of User Experiences With the Online Self-help Course Think Life","Inclusion Criteria:\n\n* age: 18 years or older\n* user of the online self-help course Think Life\n\nExclusion Criteria:\n\n* not meeting the inclusion criteria",{"count":139,"type":21},1000,"OBSERVATIONAL","This study aims to evaluate user experiences with the online self-help course Think Life, a suicide prevention intervention for individuals experiencing suicidal thoughts. Think Life was developed by the Flemish Centre of Expertise in Suicide Prevention (VLESP) and is freely available via Zelfmoord1813.be. The course was originally developed in 2014 and updated in 2025 to improve its look and feel, usability, and inclusiveness, without fundamental changes to its core content.\n\nThe researchers seek to better understand how users experience the updated version of Think Life, including perceived strengths, usability, and overall satisfaction with the course.\n\nUsers of the Think Life self-help course will be invited through a call displayed on the course homepage to voluntarily participate in an online user evaluation study. Interested individuals can access an online informed consent form via a public internet link hosted on REDCap. Participants who provide online informed consent and meet the inclusion criteria will automatically be redirected to the online questionnaire, which is also hosted on REDCap.\n\nApproximately 1000 participants aged 18 years or older can be included in this study. Participants are invited to complete a one-time online questionnaire with an estimated completion time of approximately 10 minutes.",[143,27,144],"Suicidal Ideation","mHealth Intervention","2026-06-11",{"date":147,"type":35},"2026-06-17",{"date":37,"type":21},{"date":150,"type":21},"2031-06-01",{"name":152,"class":42},"University Ghent",{"id":154,"slug":155,"hasResults":12,"nctId":156,"briefTitle":157,"officialTitle":158,"acronym":4,"eligibilityCriteria":159,"healthyVolunteers":12,"sex":17,"minAge":78,"maxAge":4,"enrollmentInfo":160,"targetDuration":4,"studyType":22,"phases":162,"briefSummary":163,"conditions":164,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":165,"lastUpdatePostDateStruct":166,"startDateStruct":168,"completionDateStruct":170,"leadSponsor":172,"locationsCount":174},"100554996","syncing-screening-and-services-for-suicide-prevention-across-health-and-jail-systems-100554996","NCT06506344","Syncing Screening and Services for Suicide Prevention Across Health and Jail Systems","Project 1 (Signature): Syncing Screening and Services for Suicide Prevention Across Health and Jail Systems","Inclusion Criteria:\n\n* 18 years of age or older\n* Released from jail between February 2021 and July of 2028\n* Had a prior primary care visit or behavioral health visit at a participating health system in the past 3 years\n\nExclusion Criteria:\n\n* Does not currently reside in the same state as the study site (i.e.- Michigan, Minnesota)\n* Would require a translator to participate in the research according to EHR data\n* Previously requested to be excluded from research",{"count":161,"type":21},5250,[56],"This study aims to harmonize jail release record data with electronic health record data in order to connect patients to an evidence-based suicide prevention and clinical care pathway upon jail release.",[27],"2026-06-02",{"date":167,"type":35},"2026-06-04",{"date":169,"type":35},"2024-06-24",{"date":171,"type":21},"2027-07",{"name":173,"class":42},"Henry Ford Health System",2,{"id":176,"slug":177,"hasResults":12,"nctId":178,"briefTitle":179,"officialTitle":179,"acronym":4,"eligibilityCriteria":180,"healthyVolunteers":12,"sex":17,"minAge":181,"maxAge":4,"enrollmentInfo":182,"targetDuration":4,"studyType":22,"phases":184,"briefSummary":185,"conditions":186,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":187,"lastUpdatePostDateStruct":188,"startDateStruct":190,"completionDateStruct":192,"leadSponsor":194,"locationsCount":196},"100554488","adapting-a-brief-suicide-intervention-for-pediatric-primary-care-enhancing-uptake-and-impact-100554488","NCT06499740","Adapting a Brief Suicide Intervention for Pediatric Primary Care: Enhancing Uptake and Impact","Adolescent Inclusion Criteria:\n\n* adolescent between the ages of 10 and 18 years old\n* speaks fluent English\n* current or past low to moderate suicide risk (denies current plan with intent to kill self)\n\nAdolescent Exclusion Criteria:\n\n* high suicide risk (endorses current plan and intent)\n* does not speak fluent English\n* does not have a primary care provider\n\nCaregiver Inclusion Criteria:\n\n* has a child who meets inclusion criteria\n* Age 18 years or older\n\nCaregiver Exclusion Criteria:\n\n* does not have a child who meets inclusion criteria\n* does not speak English\n\nProvider Inclusion Criteria:\n\n* Age 18 years or older\n* works in primary care\u002Foutpatient healthcare setting","10 Years",{"count":183,"type":21},48,[56],"Suicide is a leading cause of death among adolescents in the United States and improving access to high quality just-in-time suicide interventions to reduce risk has important public health implications. Integrating such interventions into routinely accessed settings, such as pediatric primary care, holds promise; however, many clinicians in these settings fail to adequately screen or intervene in youth suicidal thoughts and behaviors, representing a key barrier to reducing suicide. The proposed study is a pre-post quasi-experimental pilot feasibility and preliminary efficacy trial of a suicide prevention intervention informed by evidence based interventions including the SAFETY-Acute suicide prevention intervention implemented in 3 pediatric primary care clinics.",[27],"2026-05-22",{"date":189,"type":35},"2026-05-27",{"date":191,"type":35},"2026-05-04",{"date":193,"type":21},"2028-03",{"name":195,"class":42},"University of Washington",3,{"id":198,"slug":199,"hasResults":12,"nctId":200,"briefTitle":201,"officialTitle":201,"acronym":4,"eligibilityCriteria":202,"healthyVolunteers":12,"sex":17,"minAge":51,"maxAge":52,"enrollmentInfo":203,"targetDuration":4,"studyType":22,"phases":204,"briefSummary":205,"conditions":206,"keywords":208,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":213,"lastUpdatePostDateStruct":214,"startDateStruct":215,"completionDateStruct":217,"leadSponsor":219,"locationsCount":221},"100527699","preventing-suicidal-behavior-with-diverse-high-risk-youth-in-acute-care-settings-100527699","NCT06151158","Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings","Inclusion Criteria:\n\n* Suicide Risk During Acute Care Visit (At least one item in risk assessment is required; check all that apply): \\_\\_\\_ Chief complaint of suicide-related concern (via Medical Record\u002FOther), \\_\\_\\_ Active suicidal ideation endorsed in past 1 month on validated suicide screener, \\_\\_\\_ Suicidal behavior in the past 3 months on validated suicide screener, \\_\\_\\_ Clinician indicated SI in past month or SA in past 3 months.\n* Have access to a cellular phone with the ability to receive phone calls and text messages over the 12-month follow- up period\n* Adolescent must be verbally fluent and can communicate, understand, and read in either English or Spanish\n* Adolescent has been\u002Fwill be discharged from a higher level of care (i.e. inpatient, day hospital, partial hospitalization program (PHP), or residential treatment program) and back in the community within 4 weeks of their acute care visit. \\[Note: this criterion does not apply to all patients - select N\u002FA if this is the case.\n\nExclusion Criteria:\n\n* Significant cognitive or developmental delays that prevent understanding or using SPI+ or IPT-A-SCI (includes inability to communicate verbally)\n* Altered mental status (acute psychosis, intoxication, or mania)\n* Unable or unwilling to provide informed consent (adults), assent (minors), or permission (parents\u002Fcaregivers)\n* The services offered through the study are not in the best clinical interest of the patient (e.g., presenting problem requires a different level of care or treatment approach).",{"count":139,"type":21},[56],"The study will compare the effectiveness of two relatively brief and scalable evidence-based interventions: the Stanley Brown Safety Planning Intervention and Follow-up Contacts (SPI+), a suicide-specific intervention that helps people prevent suicidal crises from escalating, and Interpersonal Psychotherapy for Adolescents Ultra Short Crisis Intervention (IPT-A SCI), a psychotherapeutic crisis intervention treatment for suicidal adolescents that teaches youth skills to prevent suicidal crises and addresses interpersonal problems that lead to suicidal crises. The results will inform the future standard of care for youth at risk for suicide presenting in the ED setting. This project focuses on suicidal youth ages 12-24 in five ethnically and racially diverse urban areas: Philadelphia, Pennsylvania; Baltimore, Maryland; Chapel Hill, North Carolina; St. Petersburg, Florida; and Northern Manhattan\u002Flower Bronx\u002Feastern Queens communities in New York City, New York.",[84,207,59,27],"Suicide Ideation",[209,210,211,212,27],"Safety Planning Intervention","Ultra-Brief Crisis","Interpersonal Psychotherapy for Adolescents","Emergency Department","2026-04-28",{"date":191,"type":35},{"date":216,"type":35},"2025-03-10",{"date":218,"type":21},"2028-10-14",{"name":220,"class":42},"Johns Hopkins University",6,{"id":223,"slug":224,"hasResults":12,"nctId":225,"briefTitle":226,"officialTitle":227,"acronym":228,"eligibilityCriteria":229,"healthyVolunteers":77,"sex":17,"minAge":51,"maxAge":113,"enrollmentInfo":230,"targetDuration":4,"studyType":22,"phases":232,"briefSummary":233,"conditions":234,"keywords":235,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":239,"lastUpdatePostDateStruct":240,"startDateStruct":242,"completionDateStruct":244,"leadSponsor":246,"locationsCount":43},"100583782","bridge-the-gap-btg---black-youth-group-100583782","NCT06880809","Bridge the Gap (BTG) - Black Youth Group","Bridging the Gap: A Collaborative Intervention Group for Black Youth at Risk for Suicide","Bridge the Gap","Inclusion Criteria:\n\n* 12-17 years old\n* Identify as Black or African American or being of African descent\n* Have current suicidal ideation or suicidal ideation within the last 30 days\n* Have assent from the adolescent participant and consent from an individual's caregiver or guardian to participate.\n\nExclusion Criteria:\n\n* An active psychotic disorder or current psychosis symptoms\n* No history of suicide attempt(s) or suicide ideation in the past 30 days\n* Cognitive deficits or a medical condition diagnosed from a medical provider that precludes full understanding of study materials as assessed through an inability to complete the pre-treatment CAMS SSF \\& SSP\n* Caregivers, guardians, and\u002For the patient refuse to participate.",{"count":231,"type":21},16,[56],"The goal of this clinical trial is to develop and preliminarily test a culturally adapted suicide intervention specifically for black youth. The main question it aims to answer:\n\n-To evaluate the feasibility and acceptability of the group, as well as the preliminary efficacy of the group for decreasing suicidal thoughts and behaviors and increasing protective factors such as hope, positive ethnic identity, and family and peer support.\n\nParticipants will be asked to attend 10-week group intervention and complete pre-treatment and post-treatment assessment measures.",[27],[27,236,237,238],"Black Youth","Collaborative Assessment & Management of Suicidality (CAMS)","Group Intervention","2026-04-27",{"date":241,"type":35},"2026-04-30",{"date":243,"type":35},"2025-06-01",{"date":245,"type":21},"2027-06-01",{"name":247,"class":42},"Children's Hospital Los Angeles",{"id":249,"slug":250,"hasResults":12,"nctId":251,"briefTitle":252,"officialTitle":253,"acronym":4,"eligibilityCriteria":254,"healthyVolunteers":12,"sex":17,"minAge":78,"maxAge":4,"enrollmentInfo":255,"targetDuration":4,"studyType":22,"phases":257,"briefSummary":258,"conditions":259,"keywords":260,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":266,"lastUpdatePostDateStruct":267,"startDateStruct":269,"completionDateStruct":271,"leadSponsor":273,"locationsCount":43},"100561890","suicide-prevention-after-community-care-discharge-100561890","NCT06596044","Suicide Prevention After Community Care Discharge","Suicide Prevention In Department of Veterans Affairs Community Care Network Mental Health Settings","Inclusion Criteria:\n\n* Veteran who is eligible to receive VA services;\n* 18 years or older;\n* able to speak English;\n* received acute psychiatric treatment in a non-VA setting affiliated with VA in Northern New England;\n* endorse recent suicidal ideation (score 2+ on Beck Scale for Suicidal Ideation).\n\nExclusion Criteria:\n\n* Unable to provide informed consent;\n* Currently receiving assertive community treatment;\n* Potentially vulnerable populations including prisoners, institutionalized patients, or patients currently admitted on involuntary commitment status;\n* Study physician deems the patient is not clinically appropriate because of clinical status such as presence of active psychosis or dementia.",{"count":256,"type":21},120,[56],"The study is of high importance to Veterans' health because it will study a suicide prevention intervention in a Veteran population that is at high risk of suicide but has not been a specific focus of the Veteran Affairs' (VA's) suicide prevention efforts. Specifically, a growing number of Veterans are now receiving acute mental health treatment in VA-purchased settings (commonly referred to as Community Care). While these Veterans are at high risk of suicide after discharge, very little is known about how to prevent suicide in these Veterans. This study will directly address this problem by looking at whether a promising suicide prevention strategy called the VA Brief Intervention and Contact Program (VA BIC) can decrease the risk of suicide in Veterans after they are discharged from a non-VA mental health treatment setting. The proposed research is highly pertinent to the VA's top clinical priority-to prevent suicide in Veterans.",[27],[261,262,263,264,265,59,27],"Mental health education","Clinical trial","Suicidal ideation","Suicide, attempted","Self-injurious Behavior","2026-04-21",{"date":268,"type":35},"2026-04-24",{"date":270,"type":35},"2025-10-01",{"date":272,"type":21},"2028-09-30",{"name":274,"class":275},"VA Office of Research and Development","FED",{"id":277,"slug":278,"hasResults":12,"nctId":279,"briefTitle":280,"officialTitle":281,"acronym":282,"eligibilityCriteria":283,"healthyVolunteers":12,"sex":17,"minAge":78,"maxAge":4,"enrollmentInfo":284,"targetDuration":4,"studyType":22,"phases":285,"briefSummary":286,"conditions":287,"keywords":288,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":292,"lastUpdatePostDateStruct":293,"startDateStruct":294,"completionDateStruct":296,"leadSponsor":298,"locationsCount":43},"100602143","feasibility-study-of-a-combined-intervention-for-suicidal-inpatients-in-psychiatric-crisis-units-100602143","NCT07119671","Feasibility Study of a Combined Intervention for Suicidal Inpatients in Psychiatric Crisis Units.","Peer-Aid and Hope Box: A Feasibility Study of a Combined Intervention for Suicidal Patients Hospitalized in a Psychiatric Crisis Unit","HOPAIR","Inclusion Criteria:\n\n* Major ;\n* Hospitalized in a psychiatric crisis unit;\n* Having attempted suicide in the month preceding hospitalisation;\n* Able to give free and informed consent;\n* Having given consent;\n* French-speaking person with at least B1 level (reading and writing);\n* With access to the technical resources required for the study;\n* With a postal address.\n\nExclusion Criteria:\n\n* Presenting a relational modality incompatible with the proposed intervention (agitation, acute delirium, major cognitive disorders or psychic disorganisation, etc.);\n* Included in another research protocol related to suicide prevention.",{"count":5,"type":21},[56],"Since 2014, suicide prevention has been a national priority and is one of the 3 priority areas of the mental health plan's roadmap .\n\nHospitalization offers a crucial opportunity for life-preserving intervention . Brief health interventions and contacts are reputed to be easy to implement, effective and inexpensive .\n\nThe Hope Box is a practical emotional management tool that aims to encourage the expression of reasons for living by materializing them in a customizable box, filled with objects, photos, writings and memories in order to find comfort and hope .\n\nPeer support use their experiential knowledge of disorders and recovery to accompany people and help humanize care . They can play a decisive role in suicide prevention .\n\nIn contrast to an approach focusing only on risk factors, peer support and the Hope Box are both focus on protective factors, the strengths of the people concerned and hope.\n\nThe primary objective of this study is to evaluate the feasibility of the HOPAIR intervention (peer-support and Hope Box, completed by a reminder postcard) with suicidal people hospitalized in psychiatric crisis units. Its secondary objective is to assess the potential effectiveness on intensity of hopelessness, sense of self-efficacy, reasons for living, perceived social support and suicidal recurrence at 3 months.\n\nThis is a mixed-methods study involving 40 patients and 2 peer support in two crisis hospitalization units.",[27],[289,290,291],"Suicide prevention","Hope box","Pair aid","2026-04-16",{"date":266,"type":35},{"date":295,"type":35},"2025-09-24",{"date":297,"type":21},"2029-10-15",{"name":299,"class":42},"Hôpital le Vinatier",{"id":301,"slug":302,"hasResults":12,"nctId":303,"briefTitle":304,"officialTitle":305,"acronym":4,"eligibilityCriteria":306,"healthyVolunteers":77,"sex":17,"minAge":51,"maxAge":113,"enrollmentInfo":307,"targetDuration":4,"studyType":22,"phases":309,"briefSummary":310,"conditions":311,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":312,"lastUpdatePostDateStruct":313,"startDateStruct":314,"completionDateStruct":316,"leadSponsor":318,"locationsCount":43},"100578223","nimh-clinical-pathway-in-rural-appalachian-school-based-health-clinics-100578223","NCT06808503","NIMH Clinical Pathway in Rural Appalachian School-based Health Clinics","Implementing the NIMH Clinical Pathway in Rural Appalachian School-based Health Clinics","Inclusion Criteria:\n\n* Youth who are receiving services at the school-based health centers to participate\n* Parents must be able to give legal consent for themselves and their children to participate\n* Youth and Parent must be English-speaking\n* Youth must also be able to give signed assent to participate\n* Youth must be cognitively and medically able to participate in study activities\n\nExclusion Criteria:\n\n* Youth in state custody will be excluded from study participation due to challenges related to obtaining legal consent.",{"count":308,"type":21},30,[56],"This study will adapt and evaluate an evidence-based suicide risk screening and follow-up program in two school-based health centers in West Virginia. The suicide screening program is titled the \"NIMH Clinical Pathway\" and provides tools and procedures for routinely screening adolescents for suicide risk, completing risk assessments, safety planning, lethal means restriction, follow-up referrals, and other disposition planning as appropriate.\n\nInvestigators aim to do the following:\n\n1. Gather formative data from providers, parents, and youth to inform ways to adapt and implement the NIMH Clinical Pathway so that it can be effectively implemented in rural, Appalachian School-Based Health Centers (SBHCs).\n2. Gather preliminary data regarding the feasibility, acceptability, and effectiveness of the adapted intervention.",[27,59],"2026-04-15",{"date":266,"type":35},{"date":315,"type":35},"2024-10-02",{"date":317,"type":21},"2027-05",{"name":319,"class":42},"West Virginia University",{"id":321,"slug":322,"hasResults":12,"nctId":323,"briefTitle":324,"officialTitle":324,"acronym":4,"eligibilityCriteria":325,"healthyVolunteers":12,"sex":17,"minAge":51,"maxAge":326,"enrollmentInfo":327,"targetDuration":4,"studyType":22,"phases":329,"briefSummary":330,"conditions":331,"keywords":332,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":312,"lastUpdatePostDateStruct":336,"startDateStruct":337,"completionDateStruct":339,"leadSponsor":341,"locationsCount":43},"100563716","practice-facilitation-to-enhance-implementation-of-a-pediatric-suicide-prevention-pathway-100563716","NCT06619782","Practice Facilitation to Enhance Implementation of a Pediatric Suicide Prevention Pathway","Inclusion Criteria:\n\nYouth\n\n* between the ages of 12 and 24 years\n* present to a participating PCP and practice for a well visit\n* receive a positive ASQ screen during their well visit. Providers\n* All staff in enrolled Primary Care practices (e.g., physicians, physician assistants nurses, administrative staff) will be eligible to participate and complete relevant measures.\n\nExclusion Criteria:\n\nYouth\n\n* Over 24 years\n* Do not receive a positive ASQ screen at well visit.","80 Years",{"count":328,"type":21},360,[56],"Suicide in youth is rapidly growing to where it is the second leading cause of death across the United States. Use of available tools have shown the potential to boost primary care providers' (PCPs) detection of suicide risk and confidence and knowledge around addressing it; however, ways that work to address clinic and provider barriers that influence the ongoing implementation of a pathway to manage at-risk patients remain under researched. The proposed study will assess the impact of the investigators Facilitated Suicide Prevention program--which provides support to assist practices in integrating screening, assessment, data analysis and management procedures into routine care through feedback and coaching--on clinic use of the suicide prevention pathway and youth suicide.\n\nThe project hypothesizes that compared to PCPs in Training Only (TO) practices, those in TO+Practice Facilitation (PF) may rate the care pathway as more able to be carried out and acceptable; demonstrate greater use of the pathway components (screening, risk assessment, safety planning, lethal means safety counseling, referrals and follow-up); demonstrate higher levels of use of the pathway suicide prevention skills ; and report higher levels of confidence putting the care pathway into use.\n\nAlso we predict that, compared to youth who screen positive for suicide risk and are followed by PCPs in TO practices, those who screen positive and are followed by PCPs in TO+PF practices will be less likely to attempt suicide during the next six months; less likely to have suicidal ideation during the next 6 months; more likely to see a behavioral health provider during the next 6 months; and less likely to be sent to Emergency Departments during the next 6 months .",[27],[333,334,335],"suicide prevention","pediatric primary care","practice facilitation",{"date":292,"type":35},{"date":338,"type":35},"2025-01-28",{"date":340,"type":21},"2027-03-31",{"name":342,"class":42},"University of Colorado, Denver",{"id":344,"slug":345,"hasResults":12,"nctId":346,"briefTitle":347,"officialTitle":347,"acronym":4,"eligibilityCriteria":348,"healthyVolunteers":77,"sex":17,"minAge":349,"maxAge":52,"enrollmentInfo":350,"targetDuration":4,"studyType":22,"phases":352,"briefSummary":353,"conditions":354,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":312,"lastUpdatePostDateStruct":355,"startDateStruct":356,"completionDateStruct":358,"leadSponsor":360,"locationsCount":43},"100515677","suicide-prevention-for-substance-using-youth-experiencing-homelessness-100515677","NCT05994612","Suicide Prevention for Substance Using Youth Experiencing Homelessness","Inclusion Criteria:\n\n* 15-24 years\n* SSI-W score \\> 4 or at least one suicide attempt in prior 12 months\n* Meets criteria for homelessness\n* At least four uses of alcohol\u002Fdrugs in prior 30 days\n\nExclusion Criteria:\n\n* Youth requires psychiatric hospitalization","15 Years",{"count":351,"type":21},300,[56],"Suicide is the leading cause of death among YEH and most youth do not access services that may be available to them. Therefore, this study seeks to address this gap in the research literature with the goal to identify an effective intervention that can be readily adopted by communities that serve these youth. We will test the effects of outreach-worker delivered Cognitive Therapy for Suicide Prevention (CTSP)+Services as Usual (SAU) versus SAU alone on suicidal ideation (primary outcome), substance use and depressive symptoms (secondary outcomes) at 3, 6, 9 and 12- months.",[27],{"date":292,"type":35},{"date":357,"type":35},"2023-11-20",{"date":359,"type":21},"2030-01-01",{"name":361,"class":42},"Ohio State University",{"id":363,"slug":364,"hasResults":12,"nctId":365,"briefTitle":366,"officialTitle":367,"acronym":4,"eligibilityCriteria":368,"healthyVolunteers":77,"sex":17,"minAge":78,"maxAge":4,"enrollmentInfo":369,"targetDuration":4,"studyType":22,"phases":371,"briefSummary":372,"conditions":373,"keywords":375,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":377,"lastUpdatePostDateStruct":378,"startDateStruct":380,"completionDateStruct":382,"leadSponsor":384,"locationsCount":43},"100632034","crisis-interventions-for-pediatric-providers---autism-version-100632034","NCT07508436","Crisis Interventions for Pediatric Providers - Autism Version","Safety Planning for Autistic Youth: A Randomized Controlled Trial With Providers in Pediatric Clinics","Inclusion Criteria:\n\n* Pediatric healthcare providers serving autistic youth in a DBP clinic in the U.S.\n* Willing and able to participate in the study and its activities, including remote training in either SPI or CIPP-A (depending on randomization)\n* Willing and able to provide informed consent\n* Comfortable speaking or communicating in English\n\nExclusion Criteria:\n\n* Pediatric healthcare providers not serving autistic youth\n* Pediatric healthcare providers not practicing in a DBP clinic in the U.S.\n* Unwilling and unable to participate in the study and its activities\n* Unwilling and unable to provide informed consent\n* Not comfortable speaking or communicating in English",{"count":370,"type":21},70,[56],"The goal of this clinical trial is to examine the initial feasibility, acceptability, and effectiveness of Crisis Interventions for Pediatric Providers - Autism version (CIPP-A) for providers serving autistic youth in outpatient settings. The main question aims to answer:\n\n* Assess whether CIPP-A is feasible and acceptable to providers in development behavioral pediatric clinics?\n* Assess whether CIPP-A shows initial effectiveness in increasing providers confidence in managing suicide risk in autistic youth?\n\nIf there is a comparison group: Researchers will compare CIPP-A to general safety planning intervention (SPI) on feasibility, acceptability, and initial effectiveness.\n\nParticipants will be randomized to receive training in SPI or CIPP-A and complete online surveys and interviews over 6-months to measure feasibility, acceptability, and initial effectiveness.",[374,27],"Autism",[374,27,209,376],"Pediatric Clinics","2026-04-08",{"date":379,"type":35},"2026-04-13",{"date":381,"type":21},"2026-12-01",{"date":383,"type":21},"2028-12-31",{"name":247,"class":42},{"id":386,"slug":387,"hasResults":12,"nctId":388,"briefTitle":389,"officialTitle":390,"acronym":4,"eligibilityCriteria":391,"healthyVolunteers":12,"sex":17,"minAge":51,"maxAge":4,"enrollmentInfo":392,"targetDuration":4,"studyType":22,"phases":394,"briefSummary":395,"conditions":396,"keywords":400,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":410,"lastUpdatePostDateStruct":411,"startDateStruct":413,"completionDateStruct":415,"leadSponsor":417,"locationsCount":174},"100631882","integrating-the-youth-nominated-support-team-yst-with-cbt-for-black-youth-with-acute-suicide-risk-aim-2b-100631882","NCT07506460","Integrating the Youth Nominated Support Team (YST) With CBT for Black Youth With Acute Suicide Risk: Aim 2b","Integrating the Youth Nominated Support Team (YST) With CBT for Black Youth With Acute Suicide Risk","Youth Inclusion Criteria:\n\n* Patients that are able to provide at least one verifiable contact for emergency or tracking purposes\n* Willing to receive care at MiSide\n* Present to an acute emergency care setting with suicide risk (per protocol)\n* Self-identify as Black\n* Willing and able to complete enrollment procedures\n* Willing and able to provide signed and dated informed assent\n\nYouth Exclusion Criteria:\n\n* Unable to be consented in English\n* Do not have a parent\u002Flegal guardian available to provide consent\n* Are not able to provide informed assent or to participate in the assessment due to significant agitation, psychosis, cognitive impairment, learning disability, or medical trauma\n* Actively engaged in specialty mental health treatment\n* Participated in the Aim 2a open trial\n\nParent\u002FGuardian Inclusion Criteria:\n\n* Adults 18 years and older\n* The parent or legal guardian of a youth participating in this Aim\n* Understand written and spoken English\n* Willing and able to complete enrollment procedures\n* Willing and able to provide signed and dated informed consent\n* Need to have access to technology, either cell or an email address\n\nParent\u002FGuardian Exclusion Criteria:\n\n\\- Do not understand written and spoken English\n\nSupport Person Inclusion Criteria:\n\n* Adults 18 years and older\n* Understand written and spoken English\n* Approved to serve as a support person by the parent\u002Flegal guardian\n\nSupport Person Exclusion Criteria:\n\n* Do not understand written and spoken English\n* Not approved to serve as a support person by the parent\u002Fguardian",{"count":393,"type":21},90,[56],"This is a second pilot study being completed based on lessons learned from the Aim 2a feasibility pilot study (NCT06941311). Following modifications, the investigators are testing the acceptability, feasibility, and preliminary effectiveness of the combination of two psychosocial interventions, Cognitive Behavioral Therapy for Suicide Prevention (CBT-SP) and the computer-assisted version of the Youth-Nominated Support Team (eYST).\n\nIn this phase of the study, CBT-SP + eYST will be tested in an open trial (number of youth = 15). Investigators will recruit Black adolescents (ages 12-17) that come to an urban acute care setting for suicidal thoughts and\u002For self-injurious behaviors to receive the intervention in an outpatient community mental health agency. Participants will receive 12-14 sessions of CBT-SP in addition to YST. Participants will nominate up to 5 caring adults in their lives to serve as support persons. These support persons will attend an education\u002Forientation session to learn more about their role and how to support the youth. Support persons will have weekly contact with the youth and weekly follow up contacts from the youth's clinician\u002FYST intervention specialist.\n\nYouth will be assessed at baseline, 6 weeks, and 14 weeks. Parents will be assessed at baseline and 14 weeks. Support persons will be assessed at baseline and 14 weeks.\n\nFidelity assessments will be completed by clinicians after each session, after the YST psycho-ed session, and weekly to document contact with the support team.",[27,59,397,398,399],"Self-Injurious Behavior","Behavioral Symptoms","Behavior",[401,402,403,404,405,289,406,407,408,409],"Black youth","Acute suicide risk","Youth Nominated Support Team","Cognitive Behavioral therapy for Suicide Prevention","Community Mental Health","Behavior Therapy","Psychotherapy","Behavioral Disciplines and Activities","Cognitive Behavioral Therapy","2026-03-26",{"date":412,"type":35},"2026-04-01",{"date":414,"type":35},"2026-03-23",{"date":416,"type":21},"2026-08",{"name":418,"class":42},"University of Michigan",{"id":420,"slug":421,"hasResults":12,"nctId":422,"briefTitle":423,"officialTitle":424,"acronym":425,"eligibilityCriteria":426,"healthyVolunteers":12,"sex":17,"minAge":427,"maxAge":4,"enrollmentInfo":428,"targetDuration":4,"studyType":22,"phases":430,"briefSummary":431,"conditions":432,"keywords":434,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":438,"lastUpdatePostDateStruct":439,"startDateStruct":441,"completionDateStruct":443,"leadSponsor":445,"locationsCount":43},"100543272","caring-connections-youth-suicide-detection-and-intervention-study-100543272","NCT06353711","Caring Connections Youth Suicide Detection and Intervention Study","CA-LINC Randomized Control Trial Study","CA-LINC","Inclusion Criteria:\n\nYouth:\n\n* 13 - 19 years old\n* Current or recent history (\\\u003C90 days) of suicide ideation, planning, or attempts or nonsuicidal self-injurious behaviors per youth or caregiver self-report or positive screen on the Patient Health Questionnaire Adolescent (PHQ-A), C-SSRS, or Ask Suicide-Screening Questions (ASQ).\n* Able to fluently speak and read English\n* Youth with a prior history of difficulty accessing services.\n* Written assent to participate in the study (\\\u003C18 years old)\n* Written consent from a parent\u002Flegal guardian\u002Fcaregiver to participate in the study (\\\u003C18 years old)\n* Written consent if the youth is ages 18-19\n\nParents\u002FLegal Guardians\u002FCaregivers:\n\n* The primary caregiver of a youth who meets the above inclusion criteria for the study\n* Over the age of 18\n* Able to fluently speak and read English\n* Without intellectual disabilities\n* Provide written consent to participate\n\nMental Healthcare and\u002For Healthcare Providers and\u002For Community Stakeholders:\n\n* Mental Health, behavioral health, substance use and\u002For health-related professionals who screen\u002Fassess for mental health and\u002For suicide risk or provide referrals, treatment, or follow-up care to youth with a prior history of difficulty accessing services in the surrounding treatment areas based on this risk or community stakeholder (i.e., faith-based leaders, agency directors, advocates, school administrators, hospital\u002Fcrisis directors, topical experts, etc.).\n* Over the age of 18\n* Able to fluently speak and read English\n* Without intellectual disabilities\n* Provide written consent to participate\n\nCare Coordinators:\n\n* Care coordinators who screen\u002Fassess for mental health and\u002For suicide risk or provide referrals, treatment, or follow-up care to underserved youth in the surrounding treatment areas.\n* Over the age of 18\n* Able to fluently speak and read English\n* Without intellectual disabilities\n\nExclusion Criteria:\n\nYouth:\n\n* Youth at imminent suicide risk (reported verbally and\u002For indicated on C-SSRS)\n* Youth who exhibit severe cognitive, language, or developmental delays\n* Youth not meeting inclusion criteria\n\nParents\u002FLegal Guardians\u002FCaregivers:\n\n* Not meeting the inclusion criteria listed above.\n\nMental Healthcare and\u002For Healthcare Providers and\u002For Community Stakeholders:\n\n* Not meeting the inclusion criteria listed above.","13 Years",{"count":429,"type":21},180,[56],"The goal of this pilot randomized control trial (RCT) is to test the feasibility of Caring Connections, a Culturally Adapted Linking Individuals Needing Care (CA-LINC) suicide prevention care coordination intervention for high-risk suicidal youth. This consumer-, community-, and theory-driven care coordination intervention is designed to reduce suicide ideation and behavior (SIB) by improving service engagement. Connections is a 90-day intervention that integrates engagement and follow-up strategies to assess\u002Fmonitor suicide risk, facilitate service use referrals\u002Flinkages, develop\u002Frefine safety plans, and create villages of care. The intervention incorporates cultural promotive factors, empowerment, and motivational strategies aimed at supporting youth, enhancing strengths, promoting hope, improving family relationships, and reinforcing caring messages. Primary research questions include:\n\nIs Caring Connections feasible to use for suicidal high-risk youth? Does Caring Connections have the potential to reduce suicide ideation and behaviors among high-risk suicidal youth?\n\nFor the pilot RCT, 80 youth participants ages 13-19 who meet the inclusion criteria will be randomly assigned to one of two conditions: Caring Connections (n=40) or Treatment as Usual (n=40). Additionally, investigators will enroll 80 caregivers of youth meeting inclusion criteria and 20 Mental Healthcare, Healthcare Providers, Community Stakeholders, and\u002For Care Coordinators with experience working with suicidal youth. Researchers will compare those receiving Caring Connections with treatment as usual to see if suicidal ideation and behaviors, and engagement.",[59,27,207,433],"Suicide Attempt",[401,435,436,437],"suicide","ideation","attempts","2026-03-13",{"date":440,"type":35},"2026-03-17",{"date":442,"type":35},"2025-08-14",{"date":444,"type":21},"2026-10",{"name":446,"class":42},"University of North Carolina, Chapel Hill",{"id":448,"slug":449,"hasResults":12,"nctId":450,"briefTitle":451,"officialTitle":452,"acronym":453,"eligibilityCriteria":454,"healthyVolunteers":12,"sex":17,"minAge":78,"maxAge":4,"enrollmentInfo":455,"targetDuration":4,"studyType":22,"phases":456,"briefSummary":457,"conditions":458,"keywords":460,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":468,"lastUpdatePostDateStruct":469,"startDateStruct":470,"completionDateStruct":472,"leadSponsor":474,"locationsCount":4},"100629539","adapting-a-telehealth-intervention-for-suicide-prevention-among-patients-with-alcohol-use-disorder-in-tanzania-100629539","NCT07475988","Adapting a Telehealth Intervention for Suicide Prevention Among Patients With Alcohol Use Disorder in Tanzania","Adapting a Telehealth Intervention for Suicide Prevention Among Patients With Alcohol Use Disorder in Tanzania: IDEAS-AUD","IDEAS-AUD","Inclusion Criteria:\n\n* 18 years of age or older\n* screen positive for alcohol use disorder (AUDIT \\>=8)\n* have had suicidal thinking (C-SSRS item indicating \"actual thoughts of suicide\") in last 30 days\n* clinically sober\n* medically stable\n* have the physical and cognitive capacity to provide consent and complete study procedures\n* able to communicate in Swahili or English\n\nExclusion Criteria:\n\n* prisoners\n* decline or unable to complete informed consent",{"count":308,"type":21},[56],"Together, alcohol use and suicide account for approximately 4 million deaths per year, with a considerable burden on low and middle-income countries. Tanzania is among the world's most underserved nations for mental health treatment, with very little capacity to treat suicidality or alcohol use disorders. In this study, the researchers will adapt an evidence-based intervention for suicide prevention to address the unique needs of people with alcohol use disorders in Tanzania, and rigorously pilot test the intervention to assess its feasibility and acceptability in a Tanzanian emergency department.",[459,27],"Alcohol Use Disorder",[461,462,463,464,289,465,466,467],"Telehealth","Nurse-delivered interventions","Stigma reduction","Care engagement","Health behavior","Alcohol use disorder","Harm reduction","2026-03-12",{"date":440,"type":35},{"date":471,"type":21},"2027-08",{"date":473,"type":21},"2029-03",{"name":475,"class":42},"Duke University",{"id":477,"slug":478,"hasResults":12,"nctId":479,"briefTitle":480,"officialTitle":481,"acronym":4,"eligibilityCriteria":482,"healthyVolunteers":12,"sex":17,"minAge":78,"maxAge":4,"enrollmentInfo":483,"targetDuration":4,"studyType":22,"phases":485,"briefSummary":486,"conditions":487,"keywords":489,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":498,"lastUpdatePostDateStruct":499,"startDateStruct":500,"completionDateStruct":502,"leadSponsor":504,"locationsCount":43},"100628252","ideas-for-hope-to-reduce-suicide-risk-and-improve-hiv-care-engagement-in-tanzania-100628252","NCT07459218","IDEAS for Hope to Reduce Suicide Risk and Improve HIV Care Engagement in Tanzania","IDEAS for Hope: A Brief Telehealth Intervention to Reduce Suicide Risk and Improve HIV Care Engagement in Tanzania","Inclusion Criteria:\n\n* Adult\n* Living with HIV\n* Attending HIV care appointments\n* Self-report experiencing thoughts of suicide in the last 30 days\n\nExclusion Criteria:\n\n* Physically or cognitively unable to provide informed consent or complete study procedures",{"count":484,"type":21},600,[56],"In this project, the investigators will conduct a clinical trial to test the effectiveness and implementation of IDEAS for Hope, a 3-session telehealth counseling intervention delivered by nurses, to reduce suicidality and improve HIV care engagement among PLWH in Tanzania. The investigators will also examine mechanisms of change and implementation outcomes of the intervention, including cost-effectiveness, to disseminate a feasible, scalable, and sustainable intervention and implementation package to address a critical mental health comorbidity in HIV care.",[488,27],"HIV - Human Immunodeficiency Virus",[490,491,492,333,493,494,495,496,497],"task-shifting","task-sharing","stigma reduction","health behavior","care engagement","HIV","telehealth","nurse-led intervention","2026-03-10",{"date":468,"type":35},{"date":501,"type":21},"2026-08-01",{"date":503,"type":21},"2031-06-30",{"name":475,"class":42},{"id":506,"slug":507,"hasResults":12,"nctId":508,"briefTitle":509,"officialTitle":509,"acronym":510,"eligibilityCriteria":511,"healthyVolunteers":77,"sex":17,"minAge":78,"maxAge":512,"enrollmentInfo":513,"targetDuration":4,"studyType":22,"phases":514,"briefSummary":515,"conditions":516,"keywords":521,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":524,"lastUpdatePostDateStruct":525,"startDateStruct":527,"completionDateStruct":529,"leadSponsor":531,"locationsCount":43},"100515759","a-mixed-methods-pilot-trial-of-the-step-home-workshop-to-improve-reintegration-and-reduce-suicide-risk-for-recently-transitioned-veterans-100515759","NCT05995678","A Mixed Methods Pilot Trial of the STEP Home Workshop to Improve Reintegration and Reduce Suicide Risk for Recently Transitioned Veterans","SH-SP","Inclusion Criteria:\n\n* Recently transitioned Veterans within three years of separation from military service\n* Self-reported functional impairment or reintegration difficulties as measured by the Military-to-Civilian Questionnaire (any item score \\> 1 indicating \"some difficulty\"; M2CQ; \\[71\\])\n* Sufficient English fluency\n* Agree to participate (informed consent\u002FHIPAA)\n\nExclusion Criteria:\n\n* Active psychosis\n* Imminent or acute high suicide risk requiring immediate crisis intervention (low-moderate non-imminent risk for suicide is allowed)\n* Current moderate or severe substance use disorder\n* Neurological diagnosis excluding TBI\n\n  * Participants with mild substance use disorder will be allowed\n  * Substance use is a common behavior that may contribute to reintegration difficulties and suicide risk","65 Years",{"count":256,"type":21},[56],"Risk of Veteran suicide is elevated during the first year of transition from military service to civilian life. Most Veteran suicides occur among Veterans who are not connected to VA healthcare. Suicide prevention and connection to care are therefore critical for recently transitioning Veterans. Transitioning Veterans require services to provide them with suicide prevention education, skills to manage their transition effectively, and support in their access to VA healthcare. Convenient, accessible, palatable, patient-centered care options that are cost-effective, easy to implement nationwide, and target domains known to mitigate suicide risk are needed during this critical transition period. This proposal would bridge this important healthcare gap using STEP-Home-SP, a transdiagnostic, non-stigmatizing, skills-based workshop. STEP-Home-SP will provide Veterans with suicide prevention education, skills to improve transition, support to access VA care, and a platform to decrease social isolation early in their military to civilian transition, thereby reducing suicide risk downstream.",[517,27,88,518,519,520],"TBI","PTSD","Transdiagnostic","Anger",[88,517,519,522,27,518,523],"Intervention","Reintegration","2026-03-04",{"date":526,"type":35},"2026-03-06",{"date":528,"type":35},"2024-03-01",{"date":530,"type":21},"2027-05-31",{"name":274,"class":275},{"id":533,"slug":534,"hasResults":12,"nctId":535,"briefTitle":536,"officialTitle":537,"acronym":4,"eligibilityCriteria":538,"healthyVolunteers":77,"sex":17,"minAge":78,"maxAge":4,"enrollmentInfo":539,"targetDuration":4,"studyType":22,"phases":541,"briefSummary":542,"conditions":543,"keywords":545,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":549,"lastUpdatePostDateStruct":550,"startDateStruct":552,"completionDateStruct":554,"leadSponsor":556,"locationsCount":43},"100626192","online-suicide-prevention-and-intervention-training-for-secondary-school-counselors-100626192","NCT07432438","Online Suicide Prevention and Intervention Training for Secondary School Counselors","Development and Examination of the Efficacy of an Online Suicide Prevention and Intervention Training Program for Psychological Counselors in Secondary Education Institutions","Inclusion Criteria:\n\n* Currently working as a psychological counselor in secondary education institutions affiliated with the Ministry of National Education in Izmir, Turkey.\n* Hold a bachelor's degree in Psychology or Psychological Counseling and Guidance (PDR) from a higher education institution.\n* Possess the appropriate technical infrastructure to participate in online training (e.g., a stable internet connection, computer\u002Ftablet, and a private environment).\n* Willing to participate in the study voluntarily.\n\nExclusion Criteria:\n\n* Having lost a relative or close friend to suicide within the last year.\n* Having participated in a similar suicide prevention training program within the last 6 months.\n* Failure to attend a total of two or more training sessions during the intervention phase.",{"count":540,"type":21},60,[56],"The aim of this study is to develop and evaluate the effectiveness of the Online Suicide Prevention and Intervention Training Program (Çevrimiçi İntihar Önleme ve Müdahale Eğitim Programı - ÇİÖMEP) for school counselors working in secondary education. Suicide is a major public health concern among adolescents, and school counselors play a vital role in early identification and intervention. This research uses a randomized controlled trial (RCT) design to determine if the training improves counselors' knowledge, perceived competence, and attitudes toward suicide prevention while reducing the stigma associated with suicidal behavior.",[27,143,544],"School Counseling",[546,547,548],"Suicide Intervention Training","School Counselors","Secondary Education","2026-02-21",{"date":551,"type":35},"2026-02-25",{"date":553,"type":35},"2026-01-01",{"date":555,"type":21},"2026-11",{"name":557,"class":42},"Aydin Adnan Menderes University",{"id":559,"slug":560,"hasResults":12,"nctId":561,"briefTitle":562,"officialTitle":563,"acronym":564,"eligibilityCriteria":565,"healthyVolunteers":12,"sex":17,"minAge":78,"maxAge":4,"enrollmentInfo":566,"targetDuration":4,"studyType":22,"phases":568,"briefSummary":569,"conditions":570,"keywords":571,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":575,"lastUpdatePostDateStruct":576,"startDateStruct":578,"completionDateStruct":580,"leadSponsor":582,"locationsCount":43},"100545180","smartphone-app-enhanced-facilitation-among-veterans-in-a-mental-health-inpatient-setting-project-hope-100545180","NCT06378541","Smartphone App Enhanced Facilitation Among Veterans in a Mental Health Inpatient Setting (Project HOPE)","Virtual Hope Box Enhanced Facilitation in High-Risk Suicidal Veterans","Project HOPE","Inclusion Criteria:\n\nThose enrolled in the RCT component of this study must be:\n\n* 1\\) Veterans aged 18 or older\n* 2\\) admitted to the inpatient psychiatric unit for a recent suicidal crisis\n* 3\\) medically stable (the patient's medical and psychological fitness \\[including aggression\\] to provide informed consent will be determined by a member of the patient's treatment team)\n* 4\\) A score of 3 or greater on the Callahan 6-item cognitive screening.\n* 5\\) report current suicidal ideation (Scale for Suicidal Ideation \\[SSI\\]; sum of items 4 and 5 \\> 0, referencing the week prior to their hospitalization) as reported during the screening interview\n* 6\\) no reported use of the VHB within the past 12-months\n* 7\\) access to a smartphone to download the VHB app\n\nExclusion Criteria:\n\nVeterans will be found ineligible for the program if:\n\n* 1\\) do not understand English\n* 2\\) are prisoners\n* 3\\) are unable to provide informed consent\n* 4\\) have profound psychotic symptoms and\u002For cognitive deficits that would prevent patients from understanding the content of the intervention and\u002For assessments\n* 5\\) to not have access to a smartphone",{"count":567,"type":21},928,[56],"This study will test whether a novel intervention, Virtual Hope Box Enhanced Facilitation (VHB-EF), reduces suicide risk in Veterans after discharge from inpatient psychiatric hospitalization. Additionally, this study will also conduct interviews with Veterans and healthcare providers to explore barriers and facilitators to future adoption of the VHB-EF intervention in healthcare settings.",[27,433,207],[572,333,573,574],"smartphone application","virtual hope box","veterans","2026-02-04",{"date":577,"type":35},"2026-02-09",{"date":579,"type":35},"2025-03-26",{"date":581,"type":21},"2029-05-31",{"name":274,"class":275},{"id":584,"slug":585,"hasResults":12,"nctId":586,"briefTitle":587,"officialTitle":588,"acronym":589,"eligibilityCriteria":590,"healthyVolunteers":77,"sex":17,"minAge":427,"maxAge":591,"enrollmentInfo":592,"targetDuration":4,"studyType":22,"phases":594,"briefSummary":595,"conditions":596,"keywords":597,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":599,"lastUpdatePostDateStruct":600,"startDateStruct":602,"completionDateStruct":604,"leadSponsor":606,"locationsCount":174},"100623846","haven-connect-youth-suicide-prevention-100623846","NCT07401940","HAVEN-Connect Youth Suicide Prevention","A Multi-Generational Suicide Prevention Program in African American Churches","HAVEN","Inclusion Criteria: For churches:\n\n1. 75% of members self-identify as Black or African American,\n2. 75% are fluent in English.\n\nExclusion Criteria for Youth:\n\n1. self-identify as Black\u002FAfrican American,\n2. 13-19 years old, are fluent in English\n\nExclusion Criteria: Churches:\n\n1. 25%+ of members self-identify as non-Black or African American\n2. 25%+ are not fluent in English.\n\nExclusion Criteria for Youth:\n\n1. do not self-identify as Black\u002FAfrican American,\n2. are younger than 13 or older than 19.","19 Years",{"count":593,"type":21},240,[56],"HAVEN=CONNECT is a comprehensive depression and suicide prevention intervention that is designed to be integrated into predominantly Black churches, a strategically ideal location for mental health intervention for Black youth. HAVEN=CONNECT has three components: (1) Church Community Engagement: an interactive process of introducing the program to key church leaders and stakeholder groups. (2) Faith-Based Curriculum: educational overview for pastors, other ministerial staff and youth lay leaders on how to integrate the program into the church using communication mediums that have cultural and religious relevance in the Black Church context. (3) Youth-Connect Intervention: The goals of this project are to test the impact of HAVEN=CONNECT (HAVEN) on key intervention targets, hypothesized mediators, and build a research-informed implementation strategy for future large-scale testing.",[27],[333,401,598],"church based prevention","2026-02-03",{"date":601,"type":35},"2026-02-11",{"date":603,"type":35},"2023-06-01",{"date":605,"type":21},"2026-05-31",{"name":607,"class":42},"George Washington University",{"id":609,"slug":610,"hasResults":12,"nctId":611,"briefTitle":612,"officialTitle":613,"acronym":4,"eligibilityCriteria":614,"healthyVolunteers":12,"sex":17,"minAge":78,"maxAge":4,"enrollmentInfo":615,"targetDuration":4,"studyType":22,"phases":617,"briefSummary":618,"conditions":619,"keywords":621,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":623,"lastUpdatePostDateStruct":624,"startDateStruct":626,"completionDateStruct":628,"leadSponsor":629,"locationsCount":43},"100560036","brief-skills-for-safer-living-brief-sfsl-100560036","NCT06571916","Brief Skills for Safer Living (Brief-SfSL)","Investigating the Efficacy of a Novel Therapy for Suicide Risk in Adults: A Randomized Controlled Trial of an Intensive Single Session of \"Brief Skills for Safer Living\"","Inclusion Criteria:\n\n* Suicidal ideation in the past week\n* Access to a computer or phone with a camera\n* Access to internet\n* Access to an emergency contact and hospital within commuting distance\n* Not receiving other psychotherapy\u002Fcounselling services concurrently\n* Willing to have the session recorded to determine therapy fidelity\n* Any psychiatric diagnosis is allowed\n* Follow-up visits with a psychiatrist and\u002For family doctor where a psychotherapeutic modality (e.g., Dialectical Behavioural Therapy, psychodynamic therapy, etc.) is not being used are allowable\n\nExclusion Criteria:\n\n* Inability to undergo psychotherapy in English\n* Presence of cognitive impairment that would limit consent and understanding of Brief Skills for Safer Living\n* Active psychosis\n* Unwilling or unable to provide informed consent\n* Previously enrolled in the Brief-SfSL pilot study\n* Unwilling or unable to communicate verbally",{"count":616,"type":21},150,[56],"The goal of this project is to assess the efficacy of Brief-Skills for Safer Living (Brief-SfSL) in a randomized control trial. The investigators will be testing 150 participants Canada-wide, half of which will be randomized to receive Brief-SfSL (B-TAU) and the other half will be randomized to receive Brief-SfSL after a 3 month waitlist (WL-TAU). The main questions this study seeks to answer are:\n\n* Is B-TAU more efficacious than WL-TAU for reducing suicidal thoughts at 3 months?\n* Is B-TAU more efficacious than WL-TAU at 3 months for reducing depression severity, anxiety, and anhedonia?\n* Is B-TAU more efficacious than WL-TAU at 3 months for improving social connectedness, emotional regulation, functioning (work, life, social), executive control and social problem-solving?\n* Are adverse events equivalent between B-TAU and WL-TAU at 3 months?",[27,59,620],"Suicide and Self-harm",[435,622],"psychotherapy","2026-01-20",{"date":625,"type":35},"2026-01-22",{"date":627,"type":35},"2025-11-17",{"date":383,"type":21},{"name":630,"class":42},"Unity Health Toronto",{"id":632,"slug":633,"hasResults":12,"nctId":634,"briefTitle":635,"officialTitle":636,"acronym":4,"eligibilityCriteria":637,"healthyVolunteers":77,"sex":17,"minAge":78,"maxAge":4,"enrollmentInfo":638,"targetDuration":4,"studyType":22,"phases":640,"briefSummary":641,"conditions":642,"keywords":648,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":657,"lastUpdatePostDateStruct":658,"startDateStruct":660,"completionDateStruct":662,"leadSponsor":664,"locationsCount":43},"100615004","life-skills-training-for-soldiers-arriving-at-their-first-duty-location-100615004","NCT07286955","Life Skills Training for Soldiers Arriving at Their First Duty Location","SAFEGUARD: Life Skills Training for Soldiers Arriving at Their First Duty Location","Inclusion Criteria:\n\n* Active duty Soldiers arriving at a military installation located in the South Central U.S. for their first duty location who are attending reception center activities\n\nExclusion Criteria:\n\n* Soldiers who are not available to attend the in-person training\n* Soldiers who are under the age of 18 years old\n* Soldiers who do not have a smart phone that supports installation of the mobile app",{"count":639,"type":21},5000,[56],"This project will evaluate the effectiveness of Level Up: Boost Your Life Skills (\"Level Up\"), a strengths based, military-specific life skills training program. The goal is to determine whether Level Up can decrease suicidal-related behaviors (SRBs) and other harmful behaviors, improve mental health, enhance job performance, and reduce early military separation. The Level Up program components will be made available to participants through an online platform or mobile app that can be downloaded onto their personal mobile devices. These training materials will help Soldiers learn and practice skills. The Level Up program will also involve personalized messages from a Level Up trainer and virtual booster sessions. Soldiers arriving at their first duty location will be randomized to receive either Level Up or a single session Army bystander intervention program. Participants will complete baseline and follow up surveys 1, 3, and 6 months post-baseline.",[643,27,644,645,646,647],"Risk Reduction Behavior","Risky Behavior","Mental Health","Resilience","Performance at Work",[649,27,650,651,652,653,654,655,656],"Military Health","Harmful Behaviors","Life Skills Training","First Duty Location","Active-duty Military","Risk Reduction","Prevention","Level Up","2026-01-09",{"date":659,"type":35},"2026-01-13",{"date":661,"type":35},"2025-12-10",{"date":663,"type":21},"2029-07-01",{"name":665,"class":275},"Uniformed Services University of the Health Sciences"]