[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"supplements\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:supplements":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,56],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":33,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":44,"lastUpdatePostDateStruct":45,"startDateStruct":48,"completionDateStruct":50,"leadSponsor":52,"locationsCount":55},"100638836","whey-protein-and-adaptogenic-supplementation-in-physically-active-females-100638836",false,"NCT07594444","Whey Protein and Adaptogenic Supplementation in Physically Active Females","Whey Protein and Adaptogenic Herb Supplementation in Physically Active Females: A Randomised Controlled Trial","Inclusion Criteria:\n\n* Female, aged 18-45 years\n* Currently participating in regular structured athletic or physical training (≥3 sessions per week)\n* Free from musculoskeletal injury that would prevent testing\n* Willing to maintain usual diet and training habits during the study\n* Not currently using protein supplements or adaptogenic supplements\n\nExclusion Criteria:\n\n* Pregnant, breastfeeding, or planning pregnancy during the study period\n* Known allergy or sensitivity to dairy, pea protein, pumpkin seed, chia seed, ashwagandha, shatavari, or nightshades\n* Current use of prescribed medication that may interact with the supplements\n* Thyroid disorders, autoimmune conditions, hormone-sensitive conditions, or other medical conditions that may be affected by supplementation\n* Diagnosed eating disorder or condition affecting protein metabolism\n* Current musculoskeletal injury preventing participation in testing\n* Current use of other protein supplements or adaptogens",true,"FEMALE","18 Years","45 Years",{"count":21,"type":22},60,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to learn whether whey protein or plant protein supplements, with or without an adaptogenic herb blend, can improve strength, recovery, stress, and wellbeing in active females. The adaptogenic blend contains ashwagandha root extract and shatavari root extract.\n\nThe main questions the study aims to answer are:\n\n* Do whey protein and plant protein supplements improve muscle strength and recovery in physically active females?\n* Does adding ashwagandha and shatavari improve stress, recovery, sleep, and wellbeing compared with protein alone?\n* Are there differences between whey protein and plant protein when combined with the adaptogenic blend?\n\nResearchers will compare four supplement groups:\n\n* Whey protein\n* Whey protein with ashwagandha and shatavari\n* Plant protein\n* Plant protein with ashwagandha and shatavari\n\nParticipants will:\n\n* Take their assigned supplement daily for 6 weeks\n* Attend testing sessions before and after the intervention\n* Complete questionnaires about recovery, sleep, stress, soreness, and digestive health\n* Provide saliva samples to measure stress, hormone, immune, and inflammation markers\n* Complete muscle strength tests, including handgrip strength and push-up testing\n* Complete a 24-hour dietary recall. The study includes physically active females aged 18 to 45 years who regularly participate in structured training.",[28,29,30,31,32],"Sports Nutritional Sciences","Recovery","Muscle Strength Recovery","Muscle Strength","Supplements",[34,35,36,37,38,39,40,41,42],"Whey Protein","Plant protein","Ashwagandha","Shatavari","Adaptogens","Sports","Exercise","Active females","physically active females","RECRUITING","2026-06-03",{"date":46,"type":47},"2026-06-05","ACTUAL",{"date":49,"type":22},"2026-07-01",{"date":51,"type":22},"2026-09-20",{"name":53,"class":54},"Sports Performance and Applied Research in Trials and Analysis","NETWORK",1,{"id":57,"slug":58,"hasResults":11,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":4,"eligibilityCriteria":62,"healthyVolunteers":11,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":4,"studyType":23,"phases":68,"briefSummary":69,"conditions":70,"keywords":84,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":55},"100592604","dietary-supplements-in-patients-with-coronary-artery-bypass-grafting-for-improving-the-quality-of-healthcare-delivery-100592604","NCT06995586","Dietary Supplements in Patients With Coronary Artery Bypass Grafting for Improving the Quality of Healthcare Delivery.","The Synergistic Action of Vitamins and Dietary Supplements in Patients With Coronary Artery Bypass Grafting for Improving the Quality of Healthcare Delivery.","Inclusion Criteria:\n\n* The subjects will be people 40-80 years old, with coronary artery disease, and mental clarity who will undergo Coronary Aortic Bypass (CABG) in our clinic (Public Cardiothoracic Surgery clinic in Nicosia General Hospital) and will be randomized into 2 groups (intervention group and control group).\n* Signed consent form\n* Ability to adhere to the protocol\n\nExclusion Criteria:\n\n* Any psychiatric, neurological or motor disorder.\n* Hypersensitivity to the components of the supplement.\n* Combined Cardiac Surgery other than CABG and valve or aortic\n* Concurrent participation in other clinical trials.\n* Previous use of any probiotics, prebiotics, adsorbent dietary supplements, Vitamin C and\u002For Omega 3 fatty acids.","ALL","40 Years","80 Years",{"count":67,"type":22},108,[25],"Cardiovascular disease (CVD) remains the leading cause of death worldwide. Prevention of CAD by targeting modifiable factors remains a key public health priority. L-Ascorbic Acid (Vitamin C - Vit. C) and Omega 3 fatty acids, Eicosapentaenoic \u002F Docosahexaenoic Acid (EPO\u002FDHA), powerful but also necessary antioxidants for the human body, after observational studies as well as randomized studies seem to have a beneficial effect in the direction of the prevention of CVD with pleiotropic mechanisms. Lignin, a polymer of plant origin that is considered a dietary fiber, has a developed porous structure and can retain exogenous and endogenous toxins, and pathogenic microorganisms. Lactulose considered a prebiotic provides a selective substrate for the metabolism of saccharolytic bacteria with bifidogenic activity and multiple benefits to the host's gut health. Coronary artery bypass grafting (CABG) is an established surgical intervention and treatment of symptoms of myocardial ischemia that improves patient survival Optimal Medical Therapy (OMT) after coronary arterial bypass grafting (CABG) as described in current clinical practice could be made even better by the addition of these beneficial food supplements.\n\nA randomized controlled trial is proposed in an intervention group of 54 post-CABG patients who will be given daily orally in addition to the usual medication, 1000 mg Vitamin C, 840 mg EPO\u002FDHA, 2130 mg Lignin \\& 720 mg Lactulose and a control group of 54 patients (Control Group) in which only usual medication will be administered. The intervention will take place from the 15th postoperative day when CAGB patients are discharged and lasts for 2.5 months (10 weeks) postoperatively. The data will be collected on the 15th, 80-90th postop day in 6 months and 12 months postop and then the statistical analysis of the data will be performed. Considering the number of CABG surgeries performed electively in our clinic, this study is expected to be completed in approximately 2-3 years from the day of initiation.\n\nThe expected knowledge through the expected results such as these will emerge from this study is the potentially beneficial effect of our food supplements administration (intervention), i.e. Vitamin C, EPO\u002FDHA, Lignin \\& Lactulose, on the postoperative course of our patients. Some degree of improvement in the well-being and clinical picture of our patients postoperatively is expected, which will be thoroughly investigated in each phase of the study.",[71,72,73,74,75,32,76,77,78,79,80,81,82,83],"Cardio-pulmonary Bypass","Cardiovascular Diseases","Omega-3 Polyunsaturated Fatty Acids","Omega-3 Supplementation","Vitamin C","Postoperative Depression","Antioxidants","Lactulose","Postoperative","Optimal Medical Therapy","CABG","Coronary Artery Bypass Grafting","Prebiotics",[71,72,85,75,77,78,86,32,87,80,81,82,88,89,90,91],"Omega-3 polyunsaturated fatty acids","Omega-3 supplementation","postoperative","postoperative depression","Lignin","adsorbent","prebiotics","NOT_YET_RECRUITING","2026-05-09",{"date":95,"type":47},"2026-05-13",{"date":97,"type":22},"2026-09-01",{"date":99,"type":22},"2028-12-01",{"name":101,"class":102},"Nicosia General Hospital","OTHER"]