[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"surgical-site-infection-prevention\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:surgical-site-infection-prevention":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,54],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":53},"100644078","phase-4-investigation-of-the-preventia-irrigation-solution-for-reducing-bacteria-in-spinal-surgery-with-implants---a-comparative-study-100644078",false,"NCT07667036","Investigation of the PREVENTIA® Irrigation Solution for Reducing Bacteria in Spinal Surgery With Implants - A Comparative Study","Prevention of Bacterial Contamination in Spinal Fusion Surgery Using Polyhexanide-Poloxamer Wound Irrigation - a Randomized Clinical Trial","PROTECT-SPINE","Inclusion Criteria:\n\n* Age more than 18 years\n* Plan to undergo elective spinal fusion surgery (including thoracic and lumbar vertebrae, and sacrum and coccyx)\n* Informed consent as documented by signature\n\nExclusion Criteria:\n\n* Emergency spine surgery\n* Previous spine fusion surgery\n* Unable to follow the comply with the study procedure or provide informed consent\n* Known allergies to any of the products used in the trial\n* Female gender\n* Current or recent (last 14 days) antibiotic therapy\n* Participation in another trial with an antimicrobial substance within the 30 days preceding and during the present trial\n* Known or suspected drug or alcohol abuse\n* Inability to follow the procedures of the investigation, e.g. due to language problems, psychological disorders, dementia, etc. of the subject\n* Evidence or suspicion of preexisting infection, defined as:\n\nCurrent local infection (or active treatment) involving the spine or adjacent soft tissues (e.g. spondylodiscitis, epidural or paravertebral abscess, cellulitis at the intervention site) diagnosed clinically or by imaging prior to intervention; Active systemic bacterial\u002Ffungal infection requiring antimicrobial therapy","MALE","18 Years",{"count":20,"type":21},114,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","Spinal surgery carries a risk of surgical wound infections (i.e., the entry of bacteria). Despite various preventive measures, such infections continue to occur, particularly in operations involving implants. In this study, we would like to investigate whether rinsing the surgical wound with a special irrigation solution called PREVENTIA® can reduce the number of bacteria in the wound during the operation.",[27,28,29],"Surgical Site Infection (SSI)","Spine Surgery","Surgical Site Infection Prevention",[31,32,33,34,35,36,37,38,39,40],"SSI","surgical site infection","spinal surgery","spinal fusion surgery","preventia","polyhexanide","poloxamer","biofilm","infection prevention","spondylodesis","NOT_YET_RECRUITING","2026-06-24",{"date":44,"type":45},"2026-06-29","ACTUAL",{"date":47,"type":21},"2027-01-01",{"date":49,"type":21},"2028-12-31",{"name":51,"class":52},"Universität Luzern","OTHER",1,{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":62,"sex":63,"minAge":18,"maxAge":4,"enrollmentInfo":64,"targetDuration":4,"studyType":22,"phases":66,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":77,"whyStopped":4,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":53},"100625520","effectiveness-of-digital-game-based-learning-in-teaching-surgical-site-infection-prevention-to-nursing-students-100625520","NCT07423702","Effectiveness of Digital Game-Based Learning in Teaching Surgical Site Infection Prevention to Nursing Students","Effectiveness of Digital Game-Based Learning for Teaching Surgical Site Infection Prevention Interventions: A Mixed-Methods Randomized Controlled Trial","PreSSI-DGBL","Inclusion Criteria:\n\n* Undergraduate nursing students Students who voluntarily agree to participate and provide written informed consent Students who have not previously received formal education on surgical site infection prevention Students who are able to participate in the digital game-based learning intervention and outcome assessments\n\nExclusion Criteria:\n\n* Students who have previously received advanced or certified training on surgical site infection prevention Students who fail to complete any of the assessment time points (pre-test, post-test, or retention test) Students who do not complete the digital game-based learning intervention",true,"ALL",{"count":65,"type":21},88,[67],"NA","This study aims to evaluate the effectiveness of digital game-based learning in teaching evidence-based surgical site infection prevention interventions to second-year nursing students. Using a mixed-methods randomized controlled design, students will be assigned to either a digital game-based learning group or a traditional theoretical education group.\n\nQuantitative outcomes will assess changes in students' knowledge levels and cognitive load across three measurement points (baseline, 4-week post-intervention, and 8-week follow-up). In addition, qualitative data will be collected through semi-structured interviews with students in the intervention group to explore their learning experiences and perceptions of the digital learning approach.\n\nThe findings of this study are expected to contribute to evidence-based educational strategies in nursing education, particularly in the teaching of surgical site infection prevention.",[29,70],"Nursing Education",[72,73,74,75,76],"Digital Game-Based Learning","Surgical Site Infection","Nursing Students","Educational Intervention","Infection Prevention","RECRUITING","2026-02-19",{"date":80,"type":45},"2026-02-23",{"date":82,"type":45},"2026-02-16",{"date":84,"type":21},"2026-05",{"name":86,"class":52},"hatice akaltun"]