[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"swallowing-function\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:swallowing-function":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,48,76,108],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100639039","ddk-acoustic-analysis-and-swallowing-indicators-100639039",false,"NCT07626749","DDK Acoustic Analysis and Swallowing Indicators","Acoustic Analysis of Performance in Diadochokinetic (DDK) Tasks and Swallowing Function Indicators Among Adults Across Different Age Groups","AAP-DDK","Inclusion Criteria:\n\n* 1.Community-dwelling adults aged 18 years or older, with no upper age limit.\n* 2.Ability to communicate in Mandarin or Taiwanese and understand the study procedures.\n* 3.Willingness to provide written informed consent.\n* 4 .Ability to complete the DDK tasks and RSST.\n\nExclusion Criteria:\n\n* 1.Presence of acute respiratory infection, upper respiratory inflammation, or other acute conditions that may significantly affect speech or swallowing.\n* 2.Impaired consciousness, significant cognitive deficits, or inability to understand the study procedures.\n* 3.Recent surgery or radiotherapy involving the oral cavity or pharynx that affects speech or swallowing.\n* 4.Severe hearing impairment that prevents understanding of instructions.\n* 5.Any other condition deemed unsuitable for participation by the investigators.",true,"ALL","18 Years",{"count":21,"type":22},720,"ESTIMATED","OBSERVATIONAL","This study examines whether simple speech tasks and a swallowing screening test can help identify swallowing risk in adults of different ages. Participants will complete basic questions, a swallowing self-assessment, a saliva swallowing test, and short voice recordings of rapid syllables. The study is non-invasive, takes about 75 minutes, and may help develop an easy, low-cost screening tool for early swallowing problems.",[26,27,28],"Swallowing Function","Swallowing Risk","Dysphagia",[28,26,30,31,32,33,34],"diadochokinetic","Acoustic Analysis","Repetitive Saliva Swallowing Test","EAT-10","Older Adults","NOT_YET_RECRUITING","2026-05-29",{"date":38,"type":39},"2026-06-04","ACTUAL",{"date":41,"type":22},"2026-06-15",{"date":43,"type":22},"2030-04-09",{"name":45,"class":46},"Kaohsiung Medical University","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":56,"targetDuration":58,"studyType":23,"phases":4,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":4},"100617607","quality-of-life-and-functional-outcomes-in-laryngeal-cancer-patients-100617607","NCT07320820","Quality of Life and Functional Outcomes in Laryngeal Cancer Patients","Assessment of Quality of Life, Patient Satisfaction, Swallowing Function, Voice Outcomes, Pain, and Anxiety-Depression at Baseline and at 3-, 6-, and 12-Month Follow-Up in Patients Diagnosed With Laryngeal Squamous Cell Carcinoma: A Prospective Questionnaire-Based Study","QoL in LSSC","Inclusion Criteria:\n\n* Age ≥ 18 years at the time of enrollment.\n* Histopathologically confirmed diagnosis of laryngeal squamous cell carcinoma.\n* Planned to undergo surgical treatment or radiotherapy\u002Fchemoradiotherapy as part of standard oncological care.\n* Willing and able to participate in the study and to provide written informed consent.\n* No history of psychiatric or neurological disorders that could impair comprehension, questionnaire completion, or study participation.\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years.\n* Presence of comorbid conditions that may independently affect swallowing or voice functions.\n* Patients who withdraw consent or request to discontinue participation during or after the treatment period.\n* History of psychiatric disorders or use of psychiatric medications that may interfere with study participation or completion of patient-reported outcome measures.",{"count":57,"type":22},120,"12 Months","Laryngeal squamous cell carcinomas are head and neck malignancies that directly affect both swallowing and voice functions and are associated with a significant deterioration in patients' quality of life throughout the treatment process.\n\nThe aim of this study is to evaluate quality of life, voice and swallowing functions, pain, anxiety-depression levels, and patient satisfaction at the pre-treatment period and at the 3rd, 6th, and 12th months post-treatment in patients with laryngeal malignancies, using validated questionnaires, in order to:\n\nElucidate the course of functional recovery following treatment,\n\nIndividualize rehabilitation and follow-up strategies, and\n\nExamine the relationship between functional outcomes and oncological survival.",[61,62,63,64,26,65,66],"Laryngeal Carcinoma","Quality of Life (QOL)","Patient Satisfaction","Voice Quality","Pain Management","Anxiety Depression","2026-04-21",{"date":69,"type":39},"2026-04-22",{"date":71,"type":22},"2026-04-02",{"date":73,"type":22},"2027-12-31",{"name":75,"class":46},"Saglik Bilimleri Universitesi",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":17,"sex":18,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":86,"studyType":23,"phases":4,"briefSummary":87,"conditions":88,"keywords":91,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":47},"100627949","surface-electromyographic-analysis-of-normal-swallowing-in-children-an-exploratory-study-100627949","NCT07455279","Surface Electromyographic Analysis of Normal Swallowing in Children: An Exploratory Study","Inclusion Criteria:\n\n* Children aged 2 to under 10 years\n* Children without a diagnosis of dysphagia\n* Children without congenital brain lesions or respiratory conditions (e.g., bronchopulmonary dysplasia \\[BPD\\], respiratory distress syndrome \\[RDS\\]) that may affect the swallowing process\n* Children whose legal guardians provide informed consent for participation\n* Participants who meet all of the above inclusion criteria\n\nExclusion Criteria:\n\n* Refusal to provide consent for participation in the study\n* Refusal to undergo the study procedures or assessments\n* Determined by the principal investigator to be unsuitable for participation -Meeting any of the above exclusion criteria -","2 Years","10 Years",{"count":85,"type":22},30,"1 Day","This exploratory clinical trial aims to investigate the mechanism of sequential muscle contractions during normal swallowing processes, including spoon, straw, and cup feeding, in children aged 2 to under 10 years without swallowing disorders. Surface electromyography (sEMG) will be used to evaluate activation patterns of the orbicularis oris, submental, and hyoid muscles during liquid, semi-solid, and solid intake.\n\nThe study seeks to characterize the timing, duration, amplitude, and coordination of swallowing-related muscle activity in typically developing children. Findings from this study are expected to provide foundational physiological data to inform the development of pediatric-specific neuromuscular electrical stimulation (NMES) protocols for dysphagia treatment.",[89,90,26],"Normal Pediatric Swallowing Physiology","Swallowing Muscle Activation Patterns in Children",[92,93,94,95,96,97,98],"Pediatric Swallowing","Swallowing Physiology","Surface Electromyography","Swallowing Muscle Activation","Normative Data","Deglutition","Developmental Physiology","2026-03-02",{"date":101,"type":39},"2026-03-06",{"date":103,"type":22},"2026-03-09",{"date":105,"type":22},"2028-01-31",{"name":107,"class":46},"Seoul National University Bundang Hospital",{"id":109,"slug":110,"hasResults":11,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":4,"eligibilityCriteria":114,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":115,"enrollmentInfo":116,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":118,"conditions":119,"keywords":120,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":4},"100573509","dysphagia-in-head-and-neck-cancer-with-radiation-100573509","NCT06747208","Dysphagia in Head and Neck Cancer With Radiation","The Impact of Swallowing and Nutrition in Head and Neck Cancer Patients Undergoing Chemo or Chemo-radiotherapy.","Inclusion Criteria:\n\n* Patients scheduled to undergo radiotherapy or concurrent chemoradiotherapy ;\n* Aged between 18 and 80 years;\n* Able to perform self-care independently (ECOG ≤ 2);\n* All patients provide written informed consent.\n\nExclusion Criteria:\n\n* Patients scheduled to undergo surgical treatment;\n* Patients with neuromuscular diseases, such as stroke or Parkinson's disease;\n* Patients with other diseases or complications, including heart disease classified as NYHA functional class ≥ 2 with thrombotic conditions, or lung disease classified as Hugh-Jones grade ≥ 4;\n* Patients with psychological disorders that may affect their ability to provide informed consent or comply with the study protocol;\n* Patients who do not consent to undergo high-resolution impedance manometry.","80 Years",{"count":117,"type":22},50,"This study focuses on swallowing dysfunction, a common issue affecting 60-75% of head and neck cancer patients due to tumor damage, treatment complications, and chemoradiotherapy side effects, which can lead to malnutrition and reduced quality of life. With limited research on the effects of radiation doses on swallowing muscles and nutrition, this study aims to evaluate these impacts in non-surgical patients undergoing radiotherapy, conducting assessments before treatment, three months after, and within one year post-treatment.",[26],[121,122,123],"dysphagia","head and neck cancer","radiation therapy","2024-12-18",{"date":126,"type":39},"2024-12-24",{"date":128,"type":22},"2025-01-01",{"date":130,"type":22},"2031-12-31",{"name":132,"class":46},"National Taiwan University Hospital"]