[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"sweet-cooling-ec\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:sweet-cooling-ec":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100608475","electronic-cigarettes-as-a-harm-reduction-strategy-among-people-with-opioid-use-disorder-on-buprenorphine-100608475",false,"NCT07202039","Electronic Cigarettes as a Harm Reduction Strategy Among People With Opioid Use Disorder on Buprenorphine","SWITCH","Inclusion Criteria\n\n* Age ≥21 years\n* Smoke ≥5 CPD for ≥1 year\n* Daily CC smoker\n* Willing to switch to EC\n* Exhaled CO ≥6 ppm\n* Diagnosed with OUD\n* Stable on bupropion treatment\n* In good physical and mental health\n* Able to use a smartphone\n* Willing to participate in all study components\n* Able to provide informed consent Exclusion Criteria\n* Interested in quitting CC (contemplation stage of change)\n* Use of EC on ≥4 of the past 30 days\n* Use of other tobacco products (e.g., cigars, smokeless tobacco) on ≥9 days of the past 30 days\n* Use of nicotine replacement therapy, smoking cessation medication, or a cessation attempt in the past 30 days\n* Hypertension\n* Medical condition that would contraindicate participation\n* Meet DSM-V criteria for major depressive episode, psychotic episode, or manic episode\n* Current suicidal ideation or suicide attempt in the past year\n* Psychiatric hospitalization in the past year\n* Contemplating pregnancy, currently pregnant, or breastfeeding\n* Unable to speak and\u002For read English","ALL","21 Years",{"count":19,"type":20},90,"ESTIMATED","INTERVENTIONAL",[23],"NA","This project aims to investigate the impact of e-cigarette flavors and usage patterns on achieving harm-reduction milestones in a sample of cigarette smokers with opioid use disorder who are taking buprenorphine",[26,27,28],"Tobacco-flavored EC","Sweet-Cooling EC","Sweet Non-cooling EC",[30,31,32,33,34,35],"Cigarette Smoking","Opioid use disorder","Burprenorphine","Electronic cigarettes","Switching","Flavors","RECRUITING","2026-05-11",{"date":39,"type":40},"2026-05-12","ACTUAL",{"date":42,"type":40},"2026-04-29",{"date":44,"type":20},"2029-06-29",{"name":46,"class":47},"Prisma Health-Upstate","OTHER"]