[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"symptom-management\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:symptom-management":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,11,0,[8,47,79,121,143,176,208,230,256,292,317],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100641485","nurse-led-integrated-home-service-to-support-parents-in-symptom-management-for-children-requiring-respiratory-support-100641485",false,"NCT07652268","Nurse-led Integrated Home Service to Support Parents in Symptom Management for Children Requiring Respiratory Support","Nurse-led Integrated Home Health Service to Support Parents in Symptom Management for Children With Respiratory Support: an Effectiveness-implementation Hybrid 2 Study","Inclusion Criteria:\n\n1. parent of a child with respiratory support aged 6-month to 22 years old\n2. having a Smartphone\n3. able to communicate in Chinese or in English\n4. living with his\u002Fher child at home.\n\nExclusion Criteria:\n\n1. a reported mental health disorder\n2. engaging in other structured programs related to symptom management\n3. living in an area with no internet coverage","ALL","6 Months","22 Years",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"NA","The aims of this study are to test the effectiveness of a nurse-led integrated home health service to enhance parental self-efficacy in symptom management for children requiring respiratory support, and alongside identify factors facilitating or deterring the program implementation.\n\nA single group pre-post quasi-experimental study on parents of CMC requiring respiratory support.\n\nParents will be recruited from non-government organizations, with an estimated sample size of 80 parents. Self-administrated questionnaire, and semi-structured interview guide will be used for data collection.",[27,28,29,30,31],"Children With Medical Complexity (CMC)","Symptom Management","Nurse-led Supportive Care","Self Efficacy","Home Care Services",[33],"Children requiring respiratory support","NOT_YET_RECRUITING","2026-06-16",{"date":37,"type":38},"2026-06-18","ACTUAL",{"date":40,"type":21},"2026-07-27",{"date":42,"type":21},"2029-06-30",{"name":44,"class":45},"Dr Winsome Lam","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":46},"100585491","nurse-parental-support-using-a-proactive-mobile-app-in-symptom-management-for-children-with-mechanical-ventilation-100585491","NCT06903052","Nurse Parental Support Using a Proactive Mobile App in Symptom Management for Children With Mechanical Ventilation","Nurse Parental Support Using a Proactive Mobile App in Symptom Management for Children With Medical Complexity Requiring Mechanical Ventilation: an Effectiveness-implementation Hybrid 2 Study","The inclusion criteria for parents are:\n\n1. parent of a child with mechanical ventilation aged 2-18\n2. having a Smartphone\n3. able to communicate in Chinese and read Chinese\n4. living with his\u002Fher child at home.\n\nThe exclusion criteria for parents are:\n\n1. a reported mental health disorder\n2. engaging in other structured programs related to symptom management 3) living in an area with no internet coverage.","2 Years","18 Years",{"count":57,"type":21},52,[24],"The aims of this study are to test the effectiveness of a nurse support using a proactive mobile app to enhance parental self-efficacy in symptom management for children using mechanical ventilations, and alongside identify factors facilitating or deterring the program implementation.\n\nA single group pre-post quasi-experimental study on parents of CMC requiring mechanical ventilation.\n\nParents will be recruited from a non-government office, with an estimated sample size of 52 parents. Self-administrated questionnaire, and semi-structured interview guide will be used for data collection.",[61,28,30,62,29],"Child With Medical Complexity","Mobile Application",[64,65,66,67,68],"parental self-efficacy","children requiring mechanical ventilation","symptom management","mobile application","nurse-led parental support","RECRUITING","2026-06-11",{"date":72,"type":38},"2026-06-15",{"date":74,"type":38},"2025-05-06",{"date":76,"type":21},"2028-04-30",{"name":78,"class":45},"The Hong Kong Polytechnic University",{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":11,"sex":87,"minAge":55,"maxAge":4,"enrollmentInfo":88,"targetDuration":4,"studyType":22,"phases":90,"briefSummary":91,"conditions":92,"keywords":99,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":46},"100613993","evaluating-an-ai-based-mobile-application-for-chemotherapy-support-in-breast-cancer-patients-100613993","NCT07273812","Evaluating an AI-Based Mobile Application for Chemotherapy Support in Breast Cancer Patients","Evaluating an AI-Based Mobile Application for Chemotherapy Support in Breast Cancer Patients: A Randomized Controlled Trial","AI-ChemoApp","Inclusion Criteria:\n\n* Confirmed diagnosis of breast cancer stages I, II, or III.\n* Patients must be currently scheduled to initiate their first-ever cycle of chemotherapy.\n* Age 18 years or older.\n* Ability to understand and provide informed consent.\n* Possession of a smartphone (Android or iOS) and functional digital literacy, defined as the ability to independently navigate mobile applications, read on-screen text in Arabic, and input daily health data. (for the intervention group).\n* Willingness to comply with study procedures and follow-up schedules.\n* Ability to communicate in Arabic, as the mobile application and chatbot will be developed in Arabic.\n\nExclusion Criteria:\n\n* Patients with Stage IV (Metastatic) breast cancer.\n* Patients receiving concurrent hormonal therapy during the chemotherapy phase, to isolate chemotherapy-induced adverse events.\n\nPatients with cognitive impairment or severe psychiatric disorders that would preclude effective interaction with the mobile application or questionnaire completion.\n\n* Patients receiving palliative care where symptom management is the sole focus and active chemotherapy is not being administered with curative or life prolonging intent.\n* Patients participating in other interventional clinical trials that might confound the outcomes of this study.\n* Patients with severe comorbidities that could significantly impact their ability to participate or bias outcome measures.","FEMALE",{"count":89,"type":21},130,[24],"The goal of this clinical trial is to learn if an Arabic-language mobile application that uses artificial intelligence (AI) can help women with breast cancer during chemotherapy. The app is designed to give personalized support by reminding participants about their medications, teaching them how to manage treatment side effects, and alerting their healthcare team about serious symptoms.\n\nThe main questions this study aims to answer are:\n\n1. Does the AI-based mobile app provide accurate and safe recommendations for the patients?\n2. Does using the AI-based mobile app help lower treatment-related symptoms and side effects compared to usual care?\n3. Does the app help participants take their medications more regularly?\n4. Does it increase participants' understanding and satisfaction with the information they receive about their treatment?\n\nResearchers will compare two groups:\n\nGroup 1: Participants who use the AI-based mobile app plus usual oncology care. Group 2: Participants who receive usual care only.\n\nParticipants will:\n\n1. Use the mobile app daily for 12 weeks while receiving chemotherapy.\n2. Complete short questionnaires about symptoms, medication use, and quality of life at the start and end of the study.\n3. Report any problems or feedback about using the app. The AI app is for support and education only. It does not make treatment decisions. All information from the app will be reviewed by oncologists and pharmacists to ensure participant safety.",[93,94,95,96,97,98,28],"Breast Cancer","Breast Neoplasm","Chemotherapy-Related Toxicities","Medication Adherence","Quality of Life in Cancer Patients","Accuracy of AI App",[100,62,101,102,103,104,105,106,107,108,109,110,111],"Artificial Intelligence","digital health","supportive care","chemotherapy","patient education","Symptom Monitoring","Human-in-the-Loop AI","Breast Cancer Chemotherapy","Oncology","Arabic Language App","Pharmacy Iraq","Randomized Controlled Trial","2026-06-10",{"date":114,"type":38},"2026-06-12",{"date":116,"type":38},"2026-06-01",{"date":118,"type":21},"2026-11-06",{"name":120,"class":45},"Dena h. Al-Tameemi",{"id":122,"slug":123,"hasResults":11,"nctId":124,"briefTitle":125,"officialTitle":125,"acronym":4,"eligibilityCriteria":126,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":4,"enrollmentInfo":127,"targetDuration":4,"studyType":22,"phases":129,"briefSummary":130,"conditions":131,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":134,"lastUpdatePostDateStruct":135,"startDateStruct":137,"completionDateStruct":139,"leadSponsor":141,"locationsCount":4},"100643269","construction-and-feasibility-study-of-a-home-based-intelligent-symptom-management-program-for-lung-cancer-patients-receiving-combined-drug-therapy-based-on-symptom-journey-profiling-100643269","NCT07632703","Construction and Feasibility Study of a Home-Based Intelligent Symptom Management Program for Lung Cancer Patients Receiving Combined Drug Therapy Based on Symptom Journey Profiling","Inclusion Criteria:\n\n* Diagnosed with primary lung cancer confirmed by histology or cytology\n* First-time recipient of combination drug therapy, with an expected treatment course of at least 4 cycles; the combination regimen is not restricted\n* Aged 18 years or older\n* Able to use a smartphone\n* Eastern Cooperative Oncology Group performance status score of 2 or lower\n* Aware of their own diagnosis and medication regimen\n* Voluntarily agree to participate in this study\n\nExclusion Criteria:\n\n* History of mental illness or currently receiving mental health treatment\n* Diagnosis of malignancy in another organ site\n* Presence of cognitive impairment, indicated by 3 or more errors on the Short Portable Mental Status Questionnaire",{"count":128,"type":21},60,[24],"The goal of this clinical trial is to develop and evaluate a home-based intelligent symptom management program based on symptom journey profiles for patients with lung cancer receiving combination drug therapy. The program will be delivered through the \"Zhihu Feifang\" WeChat mini-program and is designed to help patients monitor symptoms, receive personalized symptom management recommendations, and obtain timely support during treatment intervals at home.\n\nThe study will assess the feasibility, acceptability, and preliminary effectiveness of this intelligent symptom management program.\n\nThe main research questions are as follows: (1) Is the intelligent symptom management program feasible and acceptable for patients with lung cancer receiving combination drug therapy? (2) Compared with usual care, can the program reduce symptom burden and improve symptom self-management ability? (3) Can the program improve quality of life and help patients identify and manage symptoms more promptly during treatment intervals? Researchers will compare the intelligent symptom management program with usual care to evaluate its preliminary effectiveness. Participants will be randomly assigned to either the intervention group or the usual care group.\n\nParticipants in the intervention group will: (1) Receive usual care plus the \"Zhihu Feifang\" WeChat mini-program intervention; (2) Use the mini-program during four consecutive treatment intervals, lasting approximately 4 months; (3) Complete regular symptom assessments through the mini-program; (4) Receive personalized symptom management education, coping strategies, and risk alerts based on their symptom severity and symptom changes; (5) Receive nurse monitoring and follow-up support when needed; (6) Complete questionnaires at baseline and at follow-up time points during the study; (7) Some participants may also take part in an interview after the intervention to share their experience and suggestions.\n\nParticipants in the usual care group will receive routine follow-up care, including health education, telephone follow-up, and medical visit guidance.",[132,28,133],"Lung Neoplasms","mHealth Intervention","2026-06-02",{"date":136,"type":38},"2026-06-08",{"date":138,"type":21},"2026-05-25",{"date":140,"type":21},"2027-06-30",{"name":142,"class":45},"Feifei Huang",{"id":144,"slug":145,"hasResults":11,"nctId":146,"briefTitle":147,"officialTitle":148,"acronym":4,"eligibilityCriteria":149,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":150,"enrollmentInfo":151,"targetDuration":4,"studyType":22,"phases":153,"briefSummary":154,"conditions":155,"keywords":160,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":167,"lastUpdatePostDateStruct":168,"startDateStruct":170,"completionDateStruct":172,"leadSponsor":174,"locationsCount":4},"100631332","the-effects-of-circadian-rhythm-based-progressive-relaxation-exercises-in-hemodialysis-patients-100631332","NCT07499297","THE EFFECTS OF CIRCADIAN RHYTHM-BASED PROGRESSIVE RELAXATION EXERCISES IN HEMODIALYSIS PATIENTS","THE EFFECTS OF CIRCADIAN RHYTHM-BASED PROGRESSIVE RELAXATION EXERCISES ON SYMPTOM MANAGEMENT, SLEEP QUALITY, COMFORT, AND MENTAL WELL-BEING IN HEMODIALYSIS PATIENTS","Inclusion Criteria:\n\n* 18 and 65 years of age,\n* have no mental or physical disabilities that would prevent them from answering the questions,\n* have no problems related to touch, temperature perception, hearing, or vision,\n* are relatively independent in performing daily activities,\n* do not use any pharmacological or non-pharmacological methods to facilitate sleep,\n* have been receiving hemodialysis (HD) treatment for at least 3 months,\n* are able to communicate and cooperate.\n\nExclusion Criteria:\n\n* are bedridden,\n* have physical limitations preventing them from performing relaxation exercises,\n* have been practicing relaxation exercises (such as breathing exercises, meditation, yoga, etc.) within the last 6 months,\n* are classified as intermediate type (neither type) according to the Morningness-Eveningness Questionnaire,\n* engage in regular exercise,\n* have been diagnosed with psychiatric disorders such as depression or schizophrenia,\n* do not consent to participate in the study.","65 Years",{"count":152,"type":21},75,[24],"The aim of this study is to determine the effect of Progressive Relaxation Exercise (PGE) applied according to the circadian rhythms of hemodialysis (HD) patients on symptom management, sleep quality, comfort and mental well-being levels and to examine the experiences of HD patients regarding PGE application. A sequential mixed method research design will be used in the study. The quantitative part of the study was planned as a randomized controlled double-blind experimental study. The qualitative part will be conducted as a qualitative research to be carried out with individual in-depth interview method in order to examine the opinions of the individuals in the intervention group regarding the 8-week PGE applied according to the circadian rhythm. In the collection of research data, the Introductory Information Form, Morningness-Eveningness Questionnaire (MEQ), Dialysis Symptom Index, Hemodialysis Comfort Scale - Version II, Pittsburg Sleep Quality Index (PSQI), Warwick-Edinburgh Mental Well-Being Scale (WEMIOÖ), Individual Follow-up Form, Progressive Relaxation Exercise Application Guideline (PGEUY) and In-Depth Interview Form with Individuals in the Intervention Group will be used.",[156,157,158,159,28],"Nursing","Hemodialysis Patient","Circadian Rhythm","Relaxation Exercise",[156,161,162,163,66,164,165,166],"hemodialysis","circadian rhythm","relaxation exercise","sleep quality","comfort","mental well-being","2026-04-02",{"date":169,"type":38},"2026-04-08",{"date":171,"type":21},"2026-04-01",{"date":173,"type":21},"2026-09-22",{"name":175,"class":45},"Karamanoğlu Mehmetbey University",{"id":177,"slug":178,"hasResults":11,"nctId":179,"briefTitle":180,"officialTitle":181,"acronym":182,"eligibilityCriteria":183,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":4,"enrollmentInfo":184,"targetDuration":4,"studyType":22,"phases":186,"briefSummary":187,"conditions":188,"keywords":192,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":199,"lastUpdatePostDateStruct":200,"startDateStruct":202,"completionDateStruct":204,"leadSponsor":206,"locationsCount":46},"100618496","mhealth-intervention-for-pain-self-management-100618496","NCT07332377","mHealth Intervention for Pain Self Management","PsyMINT: Mobile Health (mHealth) Intervention to Support Self-Management of Pain and Symptoms for Cancer Survivors","PsyMINT","Inclusion Criteria:\n\n* In a post-treatment stage with no evidence of disease (complete remission)\n* Diagnosed with cancer in the past three years\n* Experiencing cancer\u002Ftreatment-related pain\n* ≥ 18 years of age at the time of first diagnosis\n* Cognitively able to actively participate in an online-based study\n* Able to read, write, and understand English\n\nExclusion Criteria:\n\n* Individuals who currently use any medication for psychiatric reasons (including stimulants, and mood stabilizers)\n* Patients with major psychotic disorders (bipolar disorder or schizophrenia) and\u002For substance use disorders.\n* Those who are currently pregnant or plan to become pregnant in the next three months",{"count":185,"type":21},25,[24],"This is a feasibility pilot test of a single-arm intervention to evaluate the beta version of an mHealth app-based behavioral intervention prior to scaling for a randomized controlled trial (RCT). This mHealth intervention is designed to enhance self-efficacy and support pain and symptom self-management among post-treatment cancer survivors.",[189,190,105,28,191],"Pain","Pain Management","Cancer Survivorship",[193,194,195,196,197,198,101],"cancer survivorship","pain management","mHealth","behavioral intervention","nonpharmacologic intervention","app","2026-03-16",{"date":201,"type":38},"2026-03-18",{"date":203,"type":38},"2026-02-23",{"date":205,"type":21},"2027-03-31",{"name":207,"class":45},"Virginia Commonwealth University",{"id":209,"slug":210,"hasResults":11,"nctId":211,"briefTitle":212,"officialTitle":213,"acronym":4,"eligibilityCriteria":214,"healthyVolunteers":11,"sex":87,"minAge":55,"maxAge":4,"enrollmentInfo":215,"targetDuration":4,"studyType":22,"phases":217,"briefSummary":218,"conditions":219,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":221,"lastUpdatePostDateStruct":222,"startDateStruct":224,"completionDateStruct":226,"leadSponsor":228,"locationsCount":4},"100608379","the-effect-of-mobile-application-assisted-nursing-services-on-symptom-control-in-breast-cancer-patients-100608379","NCT07200791","The Effect of Mobile Application-Assisted Nursing Services on Symptom Control in Breast Cancer Patients","Effect of Mobile Application-Supported Nursing Service on Symptom Management in Breast Cancer Patients During Chemotherapy: A Randomized Controlled Trial","Inclusion Criteria:\n\n* 18 yaş ve üzerinde olan,\n* Çalışmaya katılmayı kabul eden,\n* Meme kanseri tanısı alan kadınlar,\n* 4AC-12 Paklitaksel tedavi protokolü uygulana,\n* Okuma yazma bilen ve iletişim problemi olmayan,\n* Akıllı telefonu olan bireyler\n* Akıllı telefonu kullanabilen bireyler\n* Verileri eksiksiz olarak dolduran bireyler\n\nExclusion Criteria:\n\n* Kardiyak problemi olan bireyler\n* Karaciğer ve böbrek yetmezliği olan bireyler\n* Mobil uygulama kullanamayan bireyler\n* Akıllı telefon kullanamayan bireyler\n* Araştırmadan ayrılmak isteyen bireyler\n* Araştırmada çeşitli sebeplerle eksik veri toplanan bireyler",{"count":216,"type":21},74,[24],"Breast cancer is the most common type of cancer in women, accounting for approximately one-quarter of all female cancers in Turkey. Chemotherapy is widely used in treatment, but it also affects healthy cells, leading to numerous side effects such as fatigue, nausea, hair loss, sleep problems, and skin and nail changes. These side effects complicate symptom management and negatively impact patients' self-efficacy and quality of life.\n\nMobile health applications allow patients to track their symptoms, communicate with healthcare professionals, and implement recommended non-pharmacological methods. Literature demonstrates that these applications reduce symptoms, improve quality of life, and enhance self-efficacy.\n\nThis research is a randomized controlled experimental trial designed to evaluate the effect of mobile app-assisted nursing services on symptom management in women diagnosed with breast cancer and undergoing chemotherapy. The research will be conducted in the chemotherapy unit of a training and research hospital in Istanbul.\n\nThe study will consist of two groups: an intervention group and a control group. Randomization will be conducted using a computer-assisted method (random.org). Based on the power analysis, 74 patients will be included in the sample for 85% power at a 95% confidence interval, a significance level of p\\\u003C0.05, and a medium effect size.\n\nInclusion criteria include individuals aged 18 years and older, female, diagnosed with breast cancer, undergoing the 4AC-12 Paclitaxel protocol, owning and using a smartphone, and consenting to participate in the study. Exclusion criteria include patients with cardiac problems, liver or kidney failure, inability to use the mobile app, or providing incomplete data.\n\nStudy data will be collected online via a mobile app. The results of the study will demonstrate the effectiveness of mobile health apps in symptom management, increasing self-efficacy, and improving quality of life.",[28,220],"Quality of Life","2025-12-02",{"date":223,"type":38},"2025-12-09",{"date":225,"type":21},"2025-12",{"date":227,"type":21},"2026-08",{"name":229,"class":45},"Fenerbahce University",{"id":231,"slug":232,"hasResults":11,"nctId":233,"briefTitle":234,"officialTitle":235,"acronym":4,"eligibilityCriteria":236,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":4,"enrollmentInfo":237,"targetDuration":4,"studyType":22,"phases":239,"briefSummary":240,"conditions":241,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":247,"lastUpdatePostDateStruct":248,"startDateStruct":250,"completionDateStruct":252,"leadSponsor":254,"locationsCount":4},"100604118","virtual-reality-intervention-for-symptom-management-in-stem-cell-transplantation-100604118","NCT07145359","Virtual Reality Intervention for Symptom Management in Stem Cell Transplantation","Development and Evaluation of A Virtual Reality Intervention for Symptoms Management During Hematopoietic Stem Cell Transplantation","Inclusion Criteria:\n\n* Patients aged 18 years or older\n* Able to speak and understand Turkish\n* Scheduled to undergo allogeneic hematopoietic stem cell transplantation (HSCT)\n* Receiving stem cell products collected from peripheral blood\n* Voluntarily agree to participate in the study and provide informed consent\n\nExclusion Criteria:\n\n* Undergoing autologous hematopoietic stem cell transplantation\n* Receiving stem cell products collected from bone marrow\n* Diagnosed with medical or psychiatric comorbidities that could interfere with participation, as reported by the healthcare team\n* Presenting infection symptoms (e.g., respiratory, gastrointestinal) that may contaminate study equipment, as identified by the healthcare team\n* Having visual, auditory, verbal, or cognitive impairments that may prevent interaction with the VR equipment\n* Previously received any form of hematopoietic stem cell transplantation",{"count":238,"type":21},30,[24],"The goal of this clinical trial is to evaluate whether a virtual reality (VR) intervention based on the Symptom Management Model can reduce physical and psychosocial symptoms during hematopoietic stem cell transplantation (HSCT) in adult patients undergoing allogeneic transplantation.\n\nThe main questions it aims to answer are:\n\nDoes the VR intervention reduce distress levels during HSCT?\n\nDoes the VR intervention decrease state anxiety and symptom severity compared to standard care?\n\nDoes the VR intervention positively affect physiological outcomes and engraftment times?\n\nResearchers will compare a group receiving standard clinical care plus a VR nature-themed video during HSCT to a group receiving standard care only to see if the VR intervention improves symptom management outcomes.\n\nParticipants will:\n\nBe randomly assigned to either the intervention or control group.\n\nIn the intervention group:\n\nWatch a 15-minute nature-themed VR video during stem cell infusion using Meta Quest 3.\n\nThe video content will be specifically created by the research team based on the principles of Attention Restoration Theory (ART).\n\nIn both groups:\n\nComplete pre- and post-intervention assessments including:\n\nDistress Thermometer\n\nState-Trait Anxiety Inventory\n\nEdmonton Symptom Assessment Scale\n\nPhysiological measures (vital signs)\n\nEngraftment tracking\n\nSatisfaction and open-ended feedback forms",[242,243,244,28,245,246],"Cancer and \u002F or Hematological Malignancy","Hematopoetic Stem Cell Transplantation","Nursing Interventions","Virtual Reality","ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION","2025-08-21",{"date":249,"type":38},"2025-08-28",{"date":251,"type":21},"2025-09-10",{"date":253,"type":21},"2026-09-10",{"name":255,"class":45},"Halic University",{"id":257,"slug":258,"hasResults":11,"nctId":259,"briefTitle":260,"officialTitle":261,"acronym":4,"eligibilityCriteria":262,"healthyVolunteers":11,"sex":87,"minAge":55,"maxAge":150,"enrollmentInfo":263,"targetDuration":4,"studyType":22,"phases":265,"briefSummary":266,"conditions":267,"keywords":275,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":284,"lastUpdatePostDateStruct":285,"startDateStruct":287,"completionDateStruct":289,"leadSponsor":290,"locationsCount":46},"100603856","yoga-in-women-with-surgical-menopause-after-gynecological-cancer-100603856","NCT07141953","Yoga in Women With Surgical Menopause After Gynecological Cancer","The Effect of Yoga on Quality of Life, Sleep Quality, and Spiritual Well-Being in Women Who Undergo Surgical Menopause Following Gynecological Cancer Surgery: A Randomized Controlled Trial","Inclusion Criteria:\n\nAge between 18-65 years Diagnosis of primary gynecological cancer (ovarian, endometrial, cervical, vaginal, or vulvar) (Stage I-III) Ability to read, understand, and speak Turkish Completion of all adjuvant treatments (surgery, chemotherapy, and\u002For radiotherapy) at least 6 months prior Access to the internet Having a computer\u002Ftablet\u002Fphone with a camera Willingness and ability to attend at least 80% of the yoga sessions Voluntary participation in the study\n\nExclusion Criteria:\n\nAny condition that prevents communication Cognitive, sensory, or physical impairment that prevents yoga practice Diagnosis of metastatic gynecological cancer Regular yoga practice within the last 6 months (at least once a week for 8 consecutive weeks)",{"count":264,"type":21},46,[24],"This randomized controlled trial investigates the effects of yoga on quality of life, sleep quality, and spiritual well-being in women who have entered surgical menopause after gynecological cancer surgery. Yoga is expected to be a supportive intervention for symptom management and to improve overall well-being in this patient population.",[268,269,108,270,28,220,271,272,273,274],"Gynecological Oncology","Gynecology","Surgical Menopause","Sleep Quality","Well-being","Yoga","Yoga for Cancer",[276,277,278,279,66,280,164,281,282,283],"gynecological oncology","gynecology","oncology","surgical menopause","quality of life","well-being","yoga","yoga for cancer","2025-08-19",{"date":286,"type":38},"2025-08-26",{"date":288,"type":21},"2025-09-01",{"date":116,"type":21},{"name":291,"class":45},"Dokuz Eylul University",{"id":293,"slug":294,"hasResults":11,"nctId":295,"briefTitle":296,"officialTitle":297,"acronym":4,"eligibilityCriteria":298,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":4,"enrollmentInfo":299,"targetDuration":4,"studyType":22,"phases":301,"briefSummary":302,"conditions":303,"keywords":306,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":308,"lastUpdatePostDateStruct":309,"startDateStruct":311,"completionDateStruct":313,"leadSponsor":315,"locationsCount":46},"100570469","the-effectiveness-of-self-management-education-and-telephone-follow-up-in-patient-with-copd-exacerbation-100570469","NCT06707649","The Effectiveness of Self-Management Education and Telephone Follow-up in Patient with COPD Exacerbation","The Effectiveness of Self-Management Education and Telephone Follow-up on Self-Care Agency and Symptom Management in Patients with COPD Exacerbation: a Randomized Controlled Study","Inclusion Criteria:\n\n* Diagnosed with COPD for the last 1 year\n* Diagnosis of Global Initiative for Chronic Obstructive Lung Disease (GOLD) stage III or IV COPD documented by pulmonary function testing\n* Patients hospitalized for acute exacerbation of COPD;\n* Hospitalized for at least 3 days\n* Having a personal mobile phone and the ability to use it,\n* Being enough conscious and oriented to answer the questions,\n* Voluntary patients\n\nExclusion Criteria:\n\n* Under 18 years old\n* Withdrawal from the study at any phase\n* Inability to be contacted by phone\u002Fmobile phone,\n* Patient death",{"count":300,"type":21},150,[24],"According to the 2024 GOLD guidelines, Chronic Obstructive Pulmonary Disease (COPD) is defined as heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea, cough, sputum production, and\u002For exacerbations) due to abnormalities of the airways (bronchitis, bronchiolitis) and\u002For alveoli (emphysema) that cause persistent, often progressive, airflow obstruction. COPD is one of the leading causes of mortality and morbidity in Turkey and worldwide. Since COPD is an incurable and lifelong disease, it is important for patients to have high levels of self-management.\n\nThe main questions it aims to answer are:\n\n1. Does self-management education and telephone follow-up intervention effect self-care agency and symptom management in people with COPD exacerbation?\n2. Does self-management education effect self-care agency and symptom management in people with COPD exacerbation? This study will evaluate the effect of self-management education and telephone follow-up on self-care agency and symptom management. Patients hospitalized with COPD exacerbation will be trained in the hospital and will be followed up by phone call after discharge. During the study, 3 groups were planned; Group 1 will be educated and followed up by telephone Group 2 will only receive education and no telephone follow-up. Group 3 will not receive education and telephone follow-up, only standard care. It is planned to collect the data from the patients at the beginning of the study, at 1, 3 and 6 months.\n\nMain outcomes:\n\n* Level of self-care agency\n* Level of symptom management The results obtained will be interpreted by comparing between 3 groups.",[304,28,305],"COPD (Chronic Obstructive Pulmonary Disease)","Self-care Agency",[304,28,307,305],"Telephone Follow-up","2024-11-25",{"date":310,"type":38},"2024-11-27",{"date":312,"type":38},"2024-09-01",{"date":314,"type":21},"2025-10-01",{"name":316,"class":45},"Kirsehir Ahi Evran Universitesi",{"id":318,"slug":319,"hasResults":11,"nctId":320,"briefTitle":321,"officialTitle":322,"acronym":4,"eligibilityCriteria":323,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":324,"targetDuration":54,"studyType":326,"phases":4,"briefSummary":327,"conditions":328,"keywords":329,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":334,"lastUpdatePostDateStruct":335,"startDateStruct":337,"completionDateStruct":339,"leadSponsor":341,"locationsCount":46},"100340781","starlight-therapy-in-palliative-care-100340781","NCT03716999","Starlight Therapy in Palliative Care","Starlight Therapy as a Non-Pharmacological Nursing Intervention in Palliative Care","Inclusion Criteria:\n\n1\\. ESAS indicates at least one of the following symptoms:\n\n* Insomnia\n* Anxiety\n* Restlessness\n* Dyspnea\n* Pain\n\nExclusion Criteria:\n\n1. Clinical Diagnosis of blindness\n2. ESAS does not include any of the flowing symptoms:\n\n   * Insomnia\n   * Anxiety\n   * Restlessness\n   * Dyspnea\n   * Pain",{"count":325,"type":21},100,"OBSERVATIONAL","Starlight Therapy™ has been shown to help alleviate end-of-life symptoms in Palliative Care patients and reduce the need for PRN or \"as needed\" medications. This study will investigate the efficacy of this intervention on the symptom of anxiety using a mixed-method analysis.\n\nThe primary investigator hypothesizes that any anti-anxiolytic effects could be caused by the Intrinsically Photosensitive Retinal Ganglion Cell neural pathway to the amygdala.",[28],[330,331,332,333],"palliative","starlight","end-of-life symptoms","non-pharmacological","2024-08-21",{"date":336,"type":38},"2024-08-23",{"date":338,"type":21},"2026-12-15",{"date":340,"type":21},"2027-11-30",{"name":342,"class":45},"Nova Scotia Health Authority"]