[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"symptomatic-epilepsy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:symptomatic-epilepsy":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100545575","placebo-optimization-of-the-presurgical-long-term-video-eeg-monitoring-100545575",false,"NCT06383689","Placebo Optimization of the Presurgical Long-term Video-EEG Monitoring","Placebo Optimization of the Presurgical Long-term Video-EEG Monitoring (OPERA)","OPERA","Inclusion Criteria:\n\n* eligibility for presurgical epilepsy diagnostics\n\nExclusion Criteria:\n\n* inclusion criterion implies all exclusion criteria for this procedure\n* legal guardian\n* lack of consent or lack of capability to provide informed consent","ALL","18 Years",{"count":20,"type":21},90,"ESTIMATED","INTERVENTIONAL",[24],"NA","The notion of genuine placebo effects on epileptic seizure events (i.e., effects beyond methodological study artifacts) is incompatible with the standard model of epilepsy seizure genesis. In this single-blind controlled study, the effectiveness of a covered placebo on (1) the timing of the occurrence of a first epileptic seizure (\"seizure pill\") versus (2) the subjective well-being (\"comfort pill\") during pre-surgical video-EEG monitoring will be examined. It is hypothesized that a placebo effect on subjective well-being can be demonstrated, but that epileptic seizure events are not influenced by placebo.",[27],"Symptomatic Epilepsy",[29,30,31,32,33],"epilepsy","emotional well-being","placebo","video-EEG long-term monitoring","presurgical epilepsy diagnostics","RECRUITING","2024-06-07",{"date":37,"type":38},"2024-06-10","ACTUAL",{"date":40,"type":38},"2024-05-13",{"date":42,"type":21},"2026-12-31",{"name":44,"class":45},"University Hospital, Bonn","OTHER"]