[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"syndrome\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:syndrome":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100637901","comparison-of-gluteal-muscle-activation-and-core-strengthening-in-dead-butt-syndrome-syndrome-100637901",false,"NCT07576114","Comparison of Gluteal Muscle Activation and Core Strengthening in Dead Butt Syndrome Syndrome","Comparison of Gluteal Muscle Activation and Core Strengthening in Dead Butt Syndrome","Inclusion Criteria:\n\n* Symptoms persisting for more than 6 weeks (subacute or chronic cases).\n* Sedentary to moderately active individuals (i.e., not involved in heavy gluteal-strengthening or core training for at least 3 months prior to the study). vParticipants will be diagnosed with Dead Butt Syndrome based on the presence of at least two out of three of the following criteria:\n* Self-reported dull ache, discomfort, or tightness in the gluteal region worsened with prolonged sitting or walking.\n* Positive Trendelenburg Test\n* ≤ 4\u002F5 on the standard MRC grading scale\n\nExclusion Criteria:\n\n* Pregnancy or plans to become pregnant during the study period.\n* Diagnosed hip labral tears, piriformis syndrome, or sciatica unrelated to gluteal amnesia.\n* Degenerative or neurological conditions such as osteoarthritis, multiple sclerosis, stroke, or spinal cord injury.\n* History of significant spinal trauma or surgery in the past 12 months.\n* Engagement in regular physical exercise or participation in rehabilitation programs within the last 6 months.","ALL","18 Years","55 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"NA","The study design would be a Randomized Controlled Trial.This study would include a total 40 participants. 20 participants in each group. Sample size is obtained through G-power. The study duration will be 12 months after the approval from the research board. Non-probability convenience sampling will be used. Randomization will be done through sealed envelope method. The study will be conducted from Quaid-e-Azam Hospital Rawalpindi and Margalla Rehabilitation Centre.",[27],"Syndrome",[29,30,31],"Dead Butt Syndrome","Gluteal Muscle Activation","Core Strengthening","RECRUITING","2026-05-04",{"date":35,"type":36},"2026-05-08","ACTUAL",{"date":38,"type":36},"2025-12-05",{"date":40,"type":21},"2026-05-28",{"name":42,"class":43},"Riphah International University","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":57,"conditions":58,"keywords":60,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":4},"100631029","development-and-usability-evaluation-of-a-knowledge-graph-based-symptom-management-system-for-patients-with-breast-cancer-undergoing-chemotherapy-100631029","NCT07495358","Development and Usability Evaluation of a Knowledge Graph-Based Symptom Management System for Patients With Breast Cancer Undergoing Chemotherapy","Development and Usability Evaluation of a Knowledge Graph-Based Symptom Management Recommendation System for Patients With Breast Cancer Undergoing Chemotherapy","KG-SMR-BC","Inclusion Criteria:\n\n* Aged 18 to 80 years\n* Pathologically confirmed breast cancer\n* Stage I-III breast cancer\n* Planning to initiate or currently receiving neoadjuvant or adjuvant chemotherapy\n* Expected to continue chemotherapy during the study period and complete at least two treatment time points\u002Fcycles\n* Able and willing to provide informed consent\n* Able to complete basic smartphone operations and system tasks independently or with guidance from the research staff\n\nExclusion Criteria:\n\n* Recurrent or metastatic breast cancer (stage IV)\n* Significant cognitive impairment or communication barriers that preclude informed consent or completion of study procedures\n* Severe psychiatric disorders or unstable psychiatric symptoms that may interfere with study participation\n* Considered unsuitable for participation by the clinical or research team because of unstable medical condition or need for acute management","80 Years",{"count":55,"type":21},30,[24],"Patients with breast cancer patients undergoing chemotherapy commonly experience multiple co-occurring symptoms that are dynamic, interrelated, and difficult to manage using conventional approaches. Existing symptom management strategies often fail to address the complexity and evolving nature of symptom experiences during treatment.\n\nThis study aims to develop a knowledge graph-based symptom management recommendation system for patients with breast cancer undergoing chemotherapy and to evaluate its usability and preliminary effectiveness among both patients and nurses. The system integrates evidence-based guidelines, clinical expertise, and patient-reported data to provide personalized recommendations for symptom management.\n\nIn this study, patients will use the system to report symptoms and receive tailored management recommendations, while nurses will use it to support clinical decision-making and symptom management. Usability, acceptability, and user experience will be assessed for both patients and nurses, and changes in symptom burden and management outcomes will be evaluated.\n\nThe findings are expected to inform the feasibility and optimization of multi-user digital health interventions for comprehensive symptom management in oncology care.",[59,27],"Breast Neoplasms",[61,62,63,64],"breast cancer","symptom management","chemotherapy","recommender system","NOT_YET_RECRUITING","2026-03-27",{"date":68,"type":36},"2026-04-01",{"date":70,"type":21},"2026-04-15",{"date":72,"type":21},"2026-12-15",{"name":74,"class":43},"Capital Medical University"]