[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"taste-altered\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:taste-altered":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100567532","taste-alterations-study-100567532",false,"NCT06669416","Taste Alterations Study","Effects of Patient Education and Self-Management in Cancer Patients Who Experience Chemotherapy-Induced Taste Alterations","TAS","Inclusion Criteria:\n\n* Medical diagnosis of cancer with types limited to the top cancer types \\[Note: Cancer types that are rare will be excluded\\]\n* Initiating chemotherapy (first day\u002Ffirst cycle) at participating clinics\n* English speaking\u002Freading (without an interpreter)\n\nExclusion Criteria:\n\n* Substitute decision-maker (activated)\n* History of head\u002Fneck cancer or irradiation\n* Known genetic\u002Fmetabolic disorder impacting taste (preexisting dysgeusia)\n* Known eating disorder\n* Receiving enteral or parenteral nutrition (special nutritional needs)\n* Pregnant women (unique needs)\n* Patients with medical orders for end of life\u002Fhospice care","ALL","18 Years",{"count":20,"type":21},400,"ESTIMATED","INTERVENTIONAL",[24],"NA","The main questions it aims to answer are:\n\n1. Does completing a standard assessment increase the detection of chemotherapy induced taste changes compared with usual care (no assessment)? What TA are experienced? Are there any patterns in TA symptom occurrence based on age, sex, race\u002Fethnicity, cancer type, chemotherapy agent, etc.\n2. Do patients take action to deal with the TA? What strategies are used? Do patients in the intervention group use the assessments to select interventions?\n3. Do the interventions lessen TA symptoms and maintain food intake? Is the treatment (in-depth assessment and education) more effective in lessening the intensity of TA than usual care? Which level of assessment is needed to support symptom management to reduce symptom severity?\n\nParticipants will:\n\nComplete baseline assessment before starting their initial chemotherapy infusion (all patients) Participate in baseline patient education based on assigned intervention (usual care vs. treatment) Engage in TA management between chemotherapy infusion clinic visits based on education Visit the clinic for chemotherapy infusions as scheduled; Complete TA assessments and reporting based on intervention; Work with nurse coaches to answer questions and help with the intervention.\n\nComplete study data collection on the 4th chemotherapy cycle (but continue intervention) Complete final data collection at 6 months",[27,28],"Chemotherapy Side Effects","Taste, Altered",[30,31],"self-management","cluster randomized control trial","RECRUITING","2026-05-20",{"date":35,"type":36},"2026-05-22","ACTUAL",{"date":38,"type":36},"2024-12-01",{"date":40,"type":21},"2026-09",{"name":42,"class":43},"Wake Forest University Health Sciences","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":53,"phases":4,"briefSummary":54,"conditions":55,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":44},"100538166","an-investigation-into-taste-problems-associated-with-xerostomia-in-patients-with-advanced-cancer-100538166","NCT06287294","An Investigation Into Taste Problems Associated With Xerostomia in Patients With Advanced Cancer","Inclusion Criteria:\n\n* 18 years of age\n* Diagnosis of locally advanced or metastatic cancer\n* Referred to palliative care\u002Foncology services\n* Dry mouth rated 'moderate' or worse over previous 2-week period\n* Taste problems rated 'moderate' or worse over previous 2-week period\n* Good understanding of English\n\nExclusion Criteria:\n\n* Cognitive impairment (unable to provide consent \u002F complete questionnaire)\n* Dry mouth precedes cancer diagnosis.\n* Taste problems precedes cancer diagnosis.\n* Head and neck surgery\n* Head and neck radiotherapy\n* Salivary gland disorders (e.g., Sjogren's Syndrome)\n* In the 'Deteriorating' or 'Terminal' Phase of illness",{"count":52,"type":21},120,"OBSERVATIONAL","Taste problems and xerostomia (dry mouth) are common among patients with advanced cancer. These symptoms can affect the pleasure of eating and drinking, reduce dietary intake, cause low mood, and a lower quality of life. This study will explore the relationship between dry mouth and taste problems in patients with advanced cancer.",[28,56,57],"Xerostomia","Neoplasms","2024-09-05",{"date":60,"type":36},"2024-09-19",{"date":62,"type":36},"2023-08-30",{"date":64,"type":21},"2025-12-31",{"name":66,"class":43},"Our Lady's Hospice and Care Services"]